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| 1 | BUD2,encoding an S-adenosylmethionine decarboxylase,is required for Arabidopsis growth and development显示文摘Polyamines 在在植物,而是他们的准确角色调整各种各样的发展过程被含有并且他们怎么管理这些过程尚待逃犯。我们这里报导浓密的 Arabidopsis 和矮子异种, bud2,哪个从编码 S-adenosylmethionine decarboxylases (SAMDC ) 的小基因家庭的一个成员的完全的删除的结果为在 polyamine 简历的不可缺少的中介的形成必要合成小径。bud2 植物在开花期,根,和叶柄扩大了脉管的系统,并且 polyamines 的改变的动态平衡。bud2 和 samdc1 的双异种,另一个 SAMDC 成员的击倒的异种,是胚胎致命,证明 SAMDC 为植物胚胎开始是必要的。我们的结果建议 polyamines 为更高的植物的正常生长和发展被要求。 | Chunmin Ge Xia Cui Yonghong Wang Yuxin Hu Zhiming Fu Dongfen Zhang Zhukuan Cheng Jiayang Li | 2006 | Cell Research2006，16，5： | 14 |
| 2 | Association of KIR Genotypes and Haplotypes with Susceptibility to Chronic Hepatitis B Virus Infection in Chinese Han Population显示文摘Killer immunoglobulin-like receptor (KIR) genes can regulate the activation of NK and T cells upon interaction with HLA class I molecules. Hepatitis B virus (HBV) infection has been regarded as a multi-factorial disorder disease. Previous studies revealed that KIRs were involved in HCV and HIV infection or clearance. The aim of this study was to explore the possibility of the inheritance of KIR genotypes and haplotypes as a candidate for susceptibility to persistent HBV infection or HBV clearance. The sequence specific primer polymerase chain reaction (SSP-PCR) was employed to identify the KIR genes and pseudogenes in 150 chronic hepatitis B (CHB) patients, 251 spontaneously recovered (SR) controls, and 412 healthy controls. The frequencies of genotype G, M, FZ1 increased in CHB patients compared with healthy control subjects. The frequency of genotype AH was higher in SR controls than that in both CHB patients and healthy controls. The carriage frequencies of genotype G and AH were higher; while, the frequencies of AF and AJ were lower in SR controls than those in healthy control subjects. The frequency of A haplotype was lower, whereas, the frequency of B haplotype was higher in CHB patients and SR controls than those in healthy controls. In healthy controls, haplotype 4 was found lower compared with that in CHB patients and SR controls and the frequency of haplotype 5 was higher in SR controls than that in other two groups. Based on these findings, it seems that the genotypes M and FZ1 are HBV susceptive genotypes; AH, on the other hand, may be protective genotypes that facilitate the clearance of HBV. It appears that the haplotype 4 is HBV susceptive haplotype, whereas, haplotype 5 may be the protective haplotype that facilitates the clearance of HBV. | Zhiming Lu Bingchang Zhang Shijun Chen Zhongtao Gai Zhaolei Feng Xiangdong Liu Yiqing Liu Xin Wen Li Li Yulian Jiao Chunyan Ma Song Shao Xiangfa Cui Guojian Chen Jianfeng Li Yneran Zhao | 2008 | Cellular & Molecular Immunology2008，5，6： | 13 |
| 3 | The BUD2 mutation affects plant architecture through altering cytokinin and auxin responses in Arabidopsis显示文摘植物生长素和细胞激动素的比率在由支持或镇压调整天线建筑学起一个关键作用腋的芽长出。我们以前鉴别了显示的 Arabidopsis 变异的 bud2 改变了根和射击建筑学,它源于 S-adenosylmethionine decarboxylase 的 loss-of-function 4 (SAMDC4 ) 。在这研究,我们证明 BUD2 能被植物生长素导致,并且正式就职依赖于植物生长素发信号。BUD2 的变化导致弱敏到植物生长素和超敏性到细胞激动素,它被胼胝正式就职试金证实。我们的学习建议 polyamines 可以在通过影响细胞激动素和敏感的动态平衡到植物生长素和细胞激动素调整植物建筑学起他们的作用。 | Xia Cui Chunmin Ge Renxiao Wang Huanzhong Wang Weiqi Chen Zhiming Fu Xiangning Jiang Jiayang Li Yonghong Wang | 2010 | Cell Research2010，20，5： | 12 |
| 4 | Structural Surface Crack Monitoring Method Based on Electrical Potential Technique and Modern Surface Technology显示文摘Crack monitoring plays a great role in modern structural health monitoring, however, most of the conventional crack inspections have disadvantages in terms of the accuracy, expense, reliability, durability and level of instrumentation required. Thus, development of a simple and reliable crack inspection technique that allows continuous monitoring has been desired. In this paper, electrical potential technique and modern surface technology are employed together to develop a new structural surface crack monitoring method. A special crack monitoring coating sensor based on electrical potential technique was deposited on the hot spot of the structure by modern surface technology. The sensor consists of three layers: the isolated layer, the sensing layer and the protective layer. The isolated layer is prepared by anodic oxidation technology, the sensing layer is made of ion plated copper, and the protective layer is made of silicone. The thickness of each layer is at micrometer magnitude. The electrical conductivity of the sensor is very stable, and the fatigue performance of the specimen with or without coating sensor is nearly unchanged. The crack monitoring experiment result shows that there are two sudden rises of the coating sensor electrical potential values, corresponding to different stages of the crack initiation and propagation. Since the width of the surface coating sensor is only 0.5 mm, this crack monitoring sensor can detect the propagation of cracks less than 0.5 mm long. The method proposed takes the simplicity of electrical potential technique and can monitor surface crack of nearly all kinds of structures precisely. The results of this paper may form the basis of a new crack monitoring system. | CUI Ronghong HE Yuting YU Zhiming LI Hongpeng SHU Wenjun DU Jinqiang | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 7 |
| 5 | A vertically integrated eutrophication model and its application to a river-style reservoir-Fuchunjiang,China显示文摘Based on a 2-D hydrodynamic model,a vertically integrated eutrophication model was developed.The physical sub-model can be used for calculation of water density at different depths,and the water quality sub-model was used for calculation of algal growth.The cohesive and non-cohesive sediments were simulated separately with different methods.The light extinction coeffcient used in the underwater light regime sub-model was linearly related to the sum of sediment and phytoplankton biomass.Some components less important to the model were simplified to improve practicability and calculation effciency.Using field data from Fuchunjiang Reservoir,we calculated the sensitivity of ecological parameters included in this model and validated the model.The results of sensitivity analysis showed that the parameters strongly inffuenced the phytoplankton biomass,including phytoplankton maximum growth rate,respiration rate,non-predatory mortality rate,settling rate,zooplankton maximum filtration rate,specific extinction coeffcient for suspended solids and sediment oxygen demand rate.The model was calibrated by adjusting these parameters.Total chlorophyll a(chl-a) concentrations at different layers in the water column were reproduced very well by the model simulations.The simulated chl-a values were positively correlated to the measured values with Pearson correlation coeffcient of 0.92.The mean difference between measured and simulated chl-a concentrations was 12% of the measured chl-a concentration.Measured and simulated DO concentrations were also positively correlated(r = 0.74) and the mean difference was 4% of measured DO concentrations.The successful validation of model indicated that it would be very useful in water quality management and algal bloom prediction in Fuchunjiang Reservoir and a good tool for water quality regulation of other river-style reservoirs. | WU Tingfeng LUOLiancong QIN Boqiang CUI Guangbai YUZuoming YAO Zhiming | 2009 | Journal of Environmental Sciences2009，21，3： | 6 |
| 6 | Activation of Piezo1 contributes to matrix stiffness-induced angiogenesis in hepatocellular carcinoma显示文摘Background:Despite integrin being highlighted as a stiffness-sensor molecule in matrix stiffness-driven angiogenesis,other stiffness-sensor molecules and their mechanosensory pathways related to angiogenesis in hepatocellular carcinoma(HCC)remain obscure.Here,we explored the interplay between Piezo1 and integrinβ1 in the mechanosensory pathway and their effects on HCC angiogenesis to better understand matrix stiffness-induced angiogenesis.Methods:The role of Piezo1 in matrix stiffness-induced angiogenesis was investigated using orthotopic liver cancer SD rat models with high liver stiffness background,and its clinical significance was evaluated in human HCC tissues.Matrix stiffness-mediated Piezo1 upregulation and activation were assayed using an in vitro fibronectin(FN)-coated cell culture system with different stiffness,Western blotting and Ca^(2+)probe.The effects of shPiezo1-conditioned medium(CM)on angiogenesis were examined by tube formation assay,wound healing assay and angiogenesis array.The underlying mechanism by which Piezo1 participated in matrix stiffness-induced angiogenesis was analyzed by microRNA quantitative real-time polymerase chain reaction(qRT-PCR),matrix stiffness measurement,dual-luciferase reporter assay,ubiquitination assay and co-immunoprecipitation.Results:Increased matrix stiffness significantly upregulated Piezo1 expression at both cellular and tissue levels,and high expression of Piezo1 indicated an unfavorable prognosis.High matrix stiffness also noticeably enhanced the activation level of Piezo1,similar to its expression level.Piezo1 knockdown significantly suppressed tumor growth,angiogenesis,and lung metastasis of HCC rat models with high liver stiffness background.shPiezo1-CM from HCC cells attenuated tube formation and migration abilities of vascular endothelial cells remarkably,and analysis of differentially expressed pro-angiogenic factors revealed that Piezo1 promoted the expression and secretion of vascular endothelial growth factor(VEGF),CXC chemokine ligand 16(CXCL16)and insulin-like growth factor binding protein 2(IGFBP2).Matrix stiffness-caused Piezo1 upregulation/activation restrained hypoxia inducible factor-1α(HIF-1α)ubiquitination,subsequently enhanced the expression of downstream pro-angiogenic factors to accelerate HCC angiogenesis.Besides,collagen 1(COL1)-reinforced tissue stiffening resulted in more expression of Piezo1 via miR-625-5p.Conclusions:This study unravels a new mechanism by which the inte-grinβ1/Piezo1 activation/Ca2+influx/HIF-1αubiquitination/VEGF,CXCL16 and IGFBP2 pathway participates in matrix stiffness-driven HCC angiogenesis.Simultaneously,a positive feedback regulation loop as stiff matrix/integrinβ1/miR-625-5p/Piezo1 and COL1/stiffer matrix mediates matrix stiffness-caused Piezo1 upregulation. | Miao Li Xi Zhang Mimi Wang Yaohui Wang Jiali Qian Xiaoxia Xing Zhiming Wang Yang You Kun Guo Jie Chen Dongmei Gao Yan Zhao Lan Zhang Rongxin Chen Jiefeng Cui Zhenggang Ren | 2022 | Cancer Communications2022，42，11： | 3 |
| 7 | Effect of Interlayers on Microstructure and Properties of 2205/Q235B Duplex Stainless Steel Clad Plate显示文摘In this research,2205/Q235 B clad plates were prepared by a vacuum hot rolling composite process.The effects of adding Fe,Ni,and Nb interlayers on the bonding interface structures and the shear strengths of the clad steel plates were studied.The results showed that 2205 duplex stainless steel and the three interlayers produced a large amount of plastic deformation and low-angle boundaries,and the main structures were the recrystallized and deformed grains.There were many recrystallized grains in the microstructure of the Q235 B low-carbon steel due to the low deformation in the rolling process.The Fe interlayer had better wettability with the two kinds of steel,but the lower strength led to the reduction of shear strength by about14 MPa compared with the original clad steel plate.The C element in the Q235 B low-carbon steel easily diffused into the Fe interlayer,and the clad steel plate attained a poor corrosion resistance because a large decarburization area was formed.The Nb interlayer reacted with the Mo element in the 2205 duplex stainless steel to form an Nb-Mo binary alloy,which generated long-banded ferrite.The decarburization area was also produced because the Nb reacted with the C element in the Q235 B to form hard and brittle NbCx.As a result,the shear strength was significantly reduced by about 282 MPa,and the corrosion resistance of the bonding surface was deteriorated.The Ni interlayer did not react with the alloy elements in both sides,and therefore effectively prevented element diffusion and improved the corrosion resistance of the bonding surface.Due to the low strength of the Ni interlayer and the increased number of bonding surfaces of the clad steel plates,the shear strength was reduced to some extent(about 40 MPa),but it still met the engineering application standards. | Fengqiang Xiao Dongpo Wang Wenbin Hu Lei Cui Zhiming Gao Lanju Zhou | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，5： | 2 |
| 8 | Activation of the bitter taste sensor TRPM5 prevents high saltinduced cardiovascular dysfunction显示文摘High salt intake is a known risk factor of cardiovascular diseases. Our recent study demonstrated that long-term high salt intake impairs transient receptor potential channel M5(TRPM5)-mediated aversion to high salt concentrations, consequently promoting high salt intake and hypertension;however, it remains unknown whether TRPM5 activation ameliorates cardiovascular dysfunction. Herein we found that bitter melon extract(BME) and cucurbitacin E(CuE), a major compound in BME, lowered high salt-induced hypertension. Long-term BME intake significantly enhanced the aversion to high salt concentrations by upregulating TRPM5 expression and function, eventually decreasing excessive salt consumption in mice. Moreover, dietary BME ameliorated high salt-induced cardiovascular dysfunction and angiotensin II-induced hypertension in vivo. The mechanistic evidence demonstrated that dietary BME inhibited high salt-induced RhoA/Rho kinase pathway overactivation, leading to reduced phosphorylation levels of myosin light chain kinase and myosin phosphatase targeting subunit 1. Furthermore, CuE inhibited vasoconstriction by attenuating L-type Ca^(2+) channel-induced Ca^(2+) influx in vascular smooth muscle cells. To summarize, our findings indicate that dietary BME has a beneficial role in antagonizing excessive salt consumption and thus appears promising for the prevention of high salt-induced cardiovascular dysfunction. | Hao Wu Yuanting Cui Chengkang He Peng Gao Qiang Li Hexuan Zhang Yanli Jiang Yingru Hu Xiao Wei Zongshi Lu Tianyi Ma Daoyan Liu Zhiming Zhu | 2020 | Science China(Life Sciences)2020，63，11： | 2 |
| 9 | Active transfer learning of matching query results across multiple sources显示文摘 | Jie XIN Zhiming CUI Pengpeng ZHAO Tianxu HE | 2015 | Frontiers of Computer Science2015，9，4： | 2 |
| 10 | Removal mechanisms of heavy metal pollution from urban runoff in wetlands显示文摘稳固的粒子,在城市的环境的特别地城市的表面灰尘包含污染物质的大数量。城市的表面灰尘是城市的 stormwater 流量的主要污染来源,这被考虑。stormwater 流量离开洗城市的表面灰尘并且溶解吸附到灰尘上的污染物质并且最后排出进收到水身体。收到水身体的质量能被灰尘和污染物质在它败坏。弄脏的水能被沼泽地与各种各样的物理、化学、生物学的过程净化。因为处理沼泽地的纯化是一个自然过程和一个便宜方法,这些过程被采用了在城市的 stormwater 流量对待污染物质许多年。在这份报纸,我们考察了在污染物质运输期间涉及城市的环境的过程。特别地,当城市的 stormwater 流量进入沼泽地时,他们包含各种各样的物理、化学、生物学的过程的移动机制应该被理解。沼泽地能由吸收和绑定移开重金属他们并且让他们形成沉积的部分。然而,当条件变化了时,重金属能被释放进水。这个信息为为污染物质搬迁并且再使用 stormwater 的沼泽地的使用是重要的[出版摘要] | Zhiming ZHANG Baoshan CUI Xiaoyun FAN | 2012 | Frontiers of Earth Science2012，6，4： | 2 |
| 11 | Up-regulation of carcinoembryonic antigen-related cell adhesion molecule 1 in gastrointestinal cancer and its clinical relevance显示文摘 | Muqing Zhou Zhiming Jin Yiwen Liu Yiqing He Yan Du Cuixia Yang Yingzhi Wang Jiajie Hu Lian Cui Feng Gao Manlin Cao | 2017 | Acta Biochimica et Biophysica Sinica2017，49，8： | 2 |
| 12 | Encapsulation of ultrafine Pd nanoparticles within the shallow layers of UiO-67 for highly efficient hydrogenation reactions显示文摘Metal-organic frameworks(MOFs)have been used to encapsulate active metal nanoparticles(MNPs)to fabricate MNPs@MOFs composites with high catalytic efficiencies.However,the diffusion of reactants and the accessibility of MNPs located in the center of MOFs may be hindered due to the inherent microporous structures of MOFs,which would affect the catalytic activities of MNPs.Herein,we report a solvent assisted ligand exchange-hydrogen reduction(SALE-HR)strategy to selectively encapsulate ultrafine MNPs(Pd or Pt)within the shallow layers of a MOF,i.e.,UiO-67.The particle sizes of the encapsulated MNPs and the thickness of the MNPs-embedded layers can be adjusted easily by controlling the SALE conditions(e.g.time and temperature).Crucially,the LE-Pd@UiO-80-0.5 composite with the thinnest Pd-embedded layers displays remarkable catalytic efficiency with a high turnover frequency(TOF)value of 600 h^-1towards hydrogenation of nitrobenzene under 1 atm H_2at room temperature.The results indicate that the catalytic efficiency and the utilization of MNPs can be enhanced by compactly encapsulating MNPs within the shallow layers of MOFs as close to their outer surfaces as possible,owing to the short masstransfer distance and enhanced accessibility of overall MNPs. | Zhiming Cui Ting Fan Liyu Chen Ruiqi Fang Chuanmao Li Yingwei Li | 2021 | Science China Chemistry2021，64，1： | 1 |
| 13 | Robust Gray Level Watermarking Method Based on Wavelet显示文摘 | Ge Weiwei Cui Zhiming Wu Jian | 2008 | Journal of Information and Com- putational Science2008，5，1： | 1 |
| 14 | Multifractal analysis to characterize urban surface dust volume-size distribution显示文摘 | Zhiming Zhang Baoshan Cui Fengman Fang Xiaoyun Fan Honggang Zhang | 2012 | Procedia Environmental Sciences2012，，： | 1 |
| 15 | Transient receptor potential vanilloid I activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel α subunit-mediated sodium reabsorption显示文摘 | Li Li Wang FeiiWei Xing Liang Yi Cui Yuanting Gao Feng Zhong Jian Pu Yunfei Zhao Yu Yan Zhencheng Arendshorst William J Nilius Bemd Chen Jing'Liu Daoyan Zhu Zhiming | 2014 | Hypertension2014，642，： | 1 |
| 16 | Realizing a“solid to solid”process via in situ cathode electrolyte interface(CEI)by solvent-in-salt electrolyte for Li-S batteries显示文摘Lithium-sulfur batteries(LSBs)are regarded as the most promising next-generation energy system due to their high theoretical energy density.However,LSBs suffer the“shuttle effect”if undergoing the solid-liquid-solid sulfur conversion process during cycling.Herein,we design a solvent-in-salt(SIS)electrolyte with co-solvent vinylene carbonate(VC)to synthesize an in situ dense cathode electrolyte interface(CEI)and successfully change sulfur conversion into a solid-solid way to avoid shuttle effect by separating the contact of sulfur and ether solvent.Dense CEI is formed at the beginning of first discharge by the combined action of SIS electrolyte and filmogen VC.Experiments and simulations show that SIS electrolyte controls the initial formed lithium polysulfides(LiPSs)to stay very closely on the cathode surface,and then converts them into a dense CEI film.As a result,Coulombic efficiency(above 99%)and cycling performance of LSBs are improved.Furthermore,the in situ dense CEI can nearly stop the self-discharge of LSBs,and enable the LSBs to work under a pretty lean electrolyte condition. | Jiajun Huang Mengli Tao Weifeng Zhang Guangli Zheng Li Du Zhiming Cui Xiujun Wang Zhenxing Liang Shijun Liao Huiyu Song | 2023 | Nano Research2023，16，4： | 1 |
| 17 | Random characteristics of the heterogeneous structure in gas-solid fluidization显示文摘 | Heping Cui Jinghai Li Hongzhi An Min Chen Zhiming Ma Guofu Wu | 1998 | Science in China Series B: Chemistry1998，，4： | 1 |
| 18 | Depressed mitochondrial biogenesis and dynamic remodeling in mouse tibialis anterior and gastrocnemius induced by 4‐week hindlimb unloading显示文摘 | Jing Liu Yunhua Peng Zhiwei Cui Zhiming Wu Airong Qian Peng Shang Lina Qu Yinghui Li Jiankang Liu Jiangang Long | 2012 | IUBMB Life2012，，11： | 1 |
| 19 | Elevated expression of CAPON and neuronal nitric oxide synthase in the sciatic nerve of rats following constriction injury显示文摘 | Zhiming Cui Qingshan Lv Meijuan Yan Chun Cheng Zhiqin Guo Junling Yang Mengling Chen Yinyin Xia Li Zhang Aiguo Shen | 2010 | The Veterinary Journal2010，，3： | 1 |
| 20 | Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin β1显示文摘 | Yinying Dong Xiaoying Xie Zhiming Wang Chao Hu Qiongdan Zheng Yaohui Wang Rongxin Chen Tongchun Xue Jie Chen Dongmei Gao Weizhong Wu Zhenggang Ren Jiefeng Cui | 2014 | Biochemical and Biophysical Research Communications2014，，： | 1 |
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