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| 1 | Clinical utility of Epstein-Barr virus DNA and other liquid biopsy markers in nasopharyngeal carcinoma显示文摘Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor ubiquitously associated with the Epstein-Barr virus(EBV),which is highly prevalent in South China,Southeast Asia,and North Africa.Despite being a highly radio-sensitive and treatable cancer,a majority of NPC patients are diagnosed in their advanced stage,and locoregional and distant relapses following definitive treatment contribute largely to cancer-specific mortality among these patients.Given that EBV-driven NPC is the predominant variant seen in endemic regions,various EBV detection methods have been developed and are utilized in screening,prognostication,and post-treatment surveillance of NPC patients.While the Immunoglobulin A(IgA)serology assay is the most extensively studied EBV detection method,the detection of plasma EBV DNA released during replication or cellular apoptosis has shown superior outcomes in endemic population screening,prognostication,and detection of distant relapse.Furthermore,there is emerging evidence on the use of circulating tumor cells,microRNAs,DNA hypermethylation,and combination assays in various clinical scenarios.Herein,this paper provides a comprehensive overview of the relevant studies using various EBV detection techniques in the management of NPC.Specifically,the recent advances,clinical evidence,and challenges associated with the clinical application of EBV liquid biopsies in population screening,prognostication,and surveillance of NPC are presented. | Rong Tan Sean Kean Ann Phua Yoke Lim Soong Lynette Lin Ean Oon Kian Sing Chan Sasidharan Swarnalatha Lucky Jamie Mong Min Han Tan Chwee Ming Lim | 2020 | Cancer Communications2020，40，11： | 8 |
| 2 | 基于多边形比例边界有限元的复合材料裂纹扩展模拟显示文摘该文采用近年提出的多边形比例边界有限元(Polygon Scaled Boundary Finite Elements,PSBFE),结合基于拓扑的局部网格重剖分方法,首次模拟了层状复合材料交界面、不同弹性模量的圆形夹杂对复合材料裂纹扩展的影响。结果表明,该文方法可以有效模拟复合材料的裂纹扩展,算例的结果同现有文献的实验数据和数值模拟结果吻合良好,采用不同网格密度和不同裂纹扩展步长对计算结果影响不大。基于SBFEM的PSBFE可以半解析求解裂纹尖端应力奇异性,具有比FEM更高的精度。另一方面,同现有基于SBFEM的裂纹扩展方法相比,基于拓扑的局部网格重剖分的PSBFE可以处理任意复杂的二维模型,具有更好的通用性。 | 施明光 徐艳杰 钟红 Ean Tat Ooi 张楚汉 | 2014 | 工程力学2014，31，7： | 7 |
| 3 | Effect of Cu(OH) 2 on electroless copper plating 显示文摘 | SHU J GRANDJ EAN B P A KALIAGUINE S | 1997 | Ind Eng Chem Res1997，36，5： | 1 |
| 4 | Pulmonary small lymphocytic lymphoma ( mucosa-associated lymphoid tissue type) associated with pulmonary hyalinizing granuloma 显示文摘 | Ren YF Raitz EAN Lee KR | 2001 | Chest2001，120，3： | 1 |
| 5 | Setting reac- tions and compressive strength of calcium phosphate cement 显示文摘 | FUKASE Y EANES E D TAKAGI S | 1990 | Journal of Dental Research1990，69，12： | 1 |
| 6 | Graduated Compression Stockings for the Prevention of Post-operatire Venous Thromboembolism显示文摘 | Eans D | 2001 | JBI Best Practice2001，2，5： | 1 |
| 7 | Improved properties of amorphous calcium phosphate fillers in reminerlizing resin composites显示文摘 | Skrtic D Antonucci J M Eanes E D | 1996 | Dent Mater1996，12，56： | 1 |
| 8 | Rapidly forming apatitic mineral in an osteoblastic cell line (UMR 106-01 BSP)显示文摘 | Stanford CM Jacobson PA Eanes ED | 1995 | J Biol Chem1995，270，16： | 1 |
| 9 | Temporal variations in low degree zonal harmonics from starlette orbit analysis显示文摘 | Cheng M K Eanes R J Shum C K | 1989 | Geophys Res Lett1989，16，： | 1 |
| 10 | Apparent anaylose content of milled rice by near-infrared reflectance spectrophotometry显示文摘 | Delwiche S R Ean M illler R E | 1995 | Cereal Chemistry1995，72，2： | 1 |
| 11 | Human Borna disease virus infection in Australia:serological markers of infection in multi-transfused patients显示文摘 | Flower RL Kamhieh S McL ean L | 2008 | APMIS Suppl2008，，124： | 1 |
| 12 | Global gravitational changes due to atmospheric mass redistribution as observed by the Lageos nodal residual显示文摘 | Chao B F Richard Eanes | 1995 | Geophysical Journal Int1995，122，： | 1 |
| 13 | The hydrolysis of anhydrous dicalcium phosphate into hydroxyapatite显示文摘 | Ishikawa K Eanes ED | 1993 | J Dent Res1993，72，2： | 1 |
| 14 | Identification and evaluation of bacteria isolated fromroots of maize显示文摘 | Pedrinho EAN Junior RFG Campanharo JC | 2010 | Bragantia2010，69，4： | 1 |
| 15 | An algebraic approach to IP traceback显示文摘 | EAN D FRANKLIN M STUBBLEFIELD A | 2002 | ACM Transactions on Information and System Security (TISSEC)2002，5，2： | 1 |
| 16 | Global Gravitational Changes due to Atmospheric Mass Redistribution as Observed by the Lageos Nodal Residual 显示文摘 | CHAO B F EANES R J | 1995 | Geophysical Journal International1995，122，3： | 1 |
| 17 | Tidal Deceleration of the Moon's Mean Motion显示文摘 | EANES R J TAPLEY B J | 1992 | Geophys J Int1992，，108： | 1 |
| 18 | Enamel apatite: Chemistry, structure and properties显示文摘 | Eanes E D | 1979 | J Dent Res1979，58，2： | 1 |
| 19 | 显示文摘 | Boogh Louis Pettersson Bo Ean Jananders | 1999 | Polymer1999，40，： | 1 |
| 20 | Long-period Perturbations in Starlette Orbit and Tide Solution显示文摘 | SHUM C K EANES R J | 1990 | J Geophys Res1990，95，6： | 1 |
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