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| 1 | Development and Application of Hydrocracking Catalysts RHC-1/RHC-5 for Maximizing High Quality Chemical Raw Materials Yield显示文摘To adapt to the change in the demand of the oil refining market,two hydrocracking catalysts,RHC-1 and RHC-5,were developed to improve the quality of tail oil.The catalysts were designed based on the theory of selective ring-opening.By selecting more acidic molecular sieves,the problem of poor selectivity of conventional materials can be solved to properly match up to the hydrogenation performance of catalysts.Compared with the performance of previous catalysts,the quality of the tail oil achieved by the said catalysts is better,and the BMCI is reduced by 1—2 units.In the long cycle operation of the petroleum industry,the good quality of the tail oil has been verified and the adaptability of the process conditions is good.When the RHC-1 catalyst is used to process heavy feed under medium pressure,a BMCI value of about12 can be obtained along with a nearly 60%yield of tail oil.The total yield of chemical raw material(steaming cracking feed+catalytic reforming feed)can exceed 80%,and the hydrogen consumption has dropped by nearly 50%as compared to the conventional hydrocracking conversion rate.When processing a mixed CGO and VGO feed with the full conversion mode under a hydrogen pressure of 13.0 MPa,the RHC-5 catalyst can yield about 68.4%of heavy naphtha with a potential aromatic content of up to 50.6,while the total yield of chemical raw materials can reach more than 98%.The results of industrial application of these catalysts show that more than 30%of high quality tail oil can be obtained via processing of inferior quality feed,and its BMCI value can reach 10.7.The total yield of chemical raw materials can reach more than65%.The industrial operation process has implemented two operating cycles totaling 8 years. | Mao Yichao Nie Hong Li Mingfeng Hu Zhihai Zhao Guangle Zhao Yang | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，2： | 5 |
| 2 | Engineered trimeric ACE2 binds viral spike protein and locks it in'Thfee-up'conformation to potently inhibit SARS-CoV-2 infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in a severe global pandemic Following SARS-CoV,SARS-CoV-2 is yet another emerge nt beta-coronavirus threate ning human health.1 However,seventeen years after the SARS pandemic,no targeted vaccines or therapeutics have been approved for SARS,while some of them might have held promise for treating COVID-19.Many neutralizing antibodies against SARS-CoV-2 are currently being developed.However,RNA viruses are known to have high mutation rates. | Liang Guo Wenwen Bi Xinling Wang Wei Xu Renhong Yan Yuanyuan Zhang Kai Zhao Yaning Li Mingfeng Zhang Xia Cai Shibo Jiang Youhua Xie Qiang Zhou Lu Lu Bobo Dang | 2021 | Cell Research2021，31，1： | 5 |
| 3 | A DFT Study on the Adsorption Behavior of Sulfur and Nitrogen Compounds on the NiMoS Phase显示文摘The density functional theory(DFT)with dispersion corrections was used to study the adsorption behavior of sulfur and nitrogen compounds on NiMoS phase.The calculations were performed based on a hexagonal cluster model including the Mo-edge,the S-edge,and the rarely mentioned corner site.It was found that the adsorption of quinoline is stronger than that of benzothiophene at all the active sites.It indicated the origin of the inhibition effect of nitrogen compounds on HDS.And Ni atoms located around Mo-edge and corner site exhibit higher adsorption selectivity to sulfur compounds than the nitrogen ones.It means that the increase in Ni-promoting effect may weaken the inhibition effect of nitrogen compounds on HDS. | Wang Wei Li Huifeng Han Wei Zhang Le Zhao Xiaoguang Li Mingfeng | 2020 | China Petroleum Processing & Petrochemical Technology2020，22，1： | 5 |
| 4 | 2022 Chinese expert consensus and guidelines on clinical management of toxicity in anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma显示文摘Adoptive cellular immunotherapy with chimeric antigen receptor(CAR)T cells has emerged as a novel modality for treating relapsed and/or refractory B-cell non-Hodgkin lymphoma(B-NHL).With increasing approval of CAR T-cell products and advances in CAR T cell therapy,CAR T cells are expected to be used in a growing number of cases.However,CAR T-cell-associated toxicities can be severe or even fatal,thus compromising the survival benefit from this therapy.Standardizing and studying the clinical management of these toxicities are imperative.In contrast to other hematological malignancies,such as acute lymphoblastic leukemia and multiple myeloma,anti-CD19 CAR T-cell-associated toxicities in B-NHL have several distinctive features,most notably local cytokine-release syndrome(CRS).However,previously published guidelines have provided few specific recommendations for the grading and management of toxicities associated with CAR T-cell treatment for B-NHL.Consequently,we developed this consensus for the prevention,recognition,and management of these toxicities,on the basis of published literature regarding the management of anti-CD19 CAR T-cell-associated toxicities and the clinical experience of multiple Chinese institutions.This consensus refines a grading system and classification of CRS in B-NHL and corresponding measures for CRS management,and delineates comprehensive principles and exploratory recommendations for managing anti-CD19 CAR T-cell-associated toxicities in addition to CRS. | Ping Li Yang Liu Yun Liang Jian Bo Sujun Gao Yongxian Hu Yu Hu He Huang Xiaojun Huang Hongmei Jing Xiaoyan Ke Jianyong Li Yuhua Li Qifa Liu Peihua Lu Heng Mei Ting Niu Yongping Song Yuqin Song Liping Su Sanfang Tu Jianxiang Wang Depei Wu Zhao Wang Kailin Xu Zhitao Ying Qingming Yang Yajing Zhang Fengxia Shi Bin Zhang Huilai Zhang Xi Zhang Mingfeng Zhao Weili Zhao Xiangyu Zhao Liang Huang Jun Zhu Wenbin Qian Weidong Han Aibin Liang | 2023 | Cancer Biology & Medicine2023，20，2： | 3 |
| 5 | Current strategies in the diagnosis and management of chronic neutrophilic leukemia显示文摘 | Altangerel Otgonbat Zhao Mingfeng | 2014 | Chinese Medical Journal2014，，24： | 3 |
| 6 | An Experimentaland Modeling Study of Methyl Propanoate Pyrolysis At-low Pressure 显示文摘 | Zhao Long Xie Mingfeng Ye Lili | 2013 | Combustion and Flame2013，160，10： | 1 |
| 7 | Protective effect of flavonoids from Scutellaria baicalensis Georgi on cerebral ischemia injury显示文摘 | Yongyu Zhang Xiaoyan Wang Xiaorong Wang Zhaohui Xu Zhe Liu Qian Ni Xiangping Chu Mingfeng Qiu Aihua Zhao Wei Jia | 2006 | Journal of Ethnopharmacology2006，，3： | 1 |
| 8 | Efficient activation of peroxymonosulfate by hollow cobalt hydroxide for degradation of ibuprofen and theoretical study显示文摘Hollow microsphere structure cobalt hydroxide(h-Co(OH)2) was synthesized via an optimized solvothermal-hydrothermal process and applied to activate peroxymonosulfate(PMS) for degradation of a typical pharmaceutically active compound,ibuprofen(IBP).The material characterizations confirmed the presence of the microscale hollow spheres with thin nanosheets shell in h-Co(OH)2,and the crystalline phase was assigned to a-Co(OH)2.h-Co(OH)2 could efficiently activate PMS for radicals production,and 98.6% of IBP was degraded at 10 min.The activation of PMS by h-Co(OH)2 was a pHindependent process,and pH 7 was the optimum condition for the activation-degradation system.Scavenger quenching test indicated that the sulfate radical(SO4^·-) was the primary reactive oxygen species for IBP degradation,which contributed to 75.7%.Fukui index(f^-) based on density functional theory(DFT) calculation predicted the active sites of IBP molecule for SO4^·- attack,and then IBP degradation pathway was proposed by means of intermediates identification and theoretical calculation.The developed hollow Co(OH)2 used to efficiently activate PMS is promising and innovative alternative for organic contaminants removal from water and wastewater. | Mingfeng Ma Long Chen Jingzhu Zhao Wen Liu Haodong Ji | 2019 | Chinese Chemical Letters2019，30，12： | 1 |
| 9 | DFT Study of H_2 Dissociation on Mo_xS_y Clusters显示文摘A DFT study of H2 dissociation on a series of Mo x S y clusters was performed, including homolytic and heterolytic dissociation. The preference for the two pathways on these models show much difference, as the Mo coordination number increases, the homolytic dissociation becomes easier, whereas the heterolytic dissociation becomes more difficult. Furthermore, frontier orbital theory was used to analyze the dissociation mechanisms of these two pathways. It was found that the symmetry and energy gap of Mo x S y's HOMO and H2's LUMO are the decisive factors in H2 activation. | Wang Wei Zhao Xiaoguang Li Huifeng Zhou Han Li Mingfeng | 2015 | China Petroleum Processing & Petrochemical Technology2015，17，1： | 1 |
| 10 | A New Method to Detect Useless Service Failure Model in SPN 显示文摘 | Zhao Mingfeng Zhou Yajian Yang Yixian | 2010 | Journal of Convergence Information Technology2010，5，3： | 1 |
| 11 | A high-density intervarietal map of the wheat genome enriched with markers derived from expressed sequence tags显示文摘 | Shulin Xue Zhengzhi Zhang Feng Lin Zhongxin Kong Yong Cao Chunjun Li Hongying Yi Mingfeng Mei Huilan Zhu Jizhong Wu Haibin Xu Dongmei Zhao Dagang Tian Caiqin Zhang Zhengqiang Ma | 2008 | Theoretical and Applied Genetics2008，，2： | 1 |
| 12 | Gender differences in the bioavailability and pharmacokinetics ofγ-schisandrin from a Wurenchun-PVPk30soliddispersioninrats显示文摘 | Tie Zhao Mingfeng Qiu Guoxiang Xie | 2010 | Asian Journal of Traditional Medcines2010，5，6： | 1 |
| 13 | Laboratory Diagnosis and Monitoring the Viral Shedding of SARS-CoV-2 Infection显示文摘The worldwide epidemic of coronavirus disease 2019(COVID-19)is ongoing.Rapid and accurate detection of the causative virus SARSCoV-2 is vital for the treatment and control of COVID-19.In this study,the comparative sensitivity of different respiratory specimen types were retrospectively analyzed using 3,552 clinical samples from 410 COVID-19 patients confirmed by Guangdong CDC(Center for Disease Control and Prevention).Except for bronchoalveolar lavage fluid(BALF),the sputum possessed the highest positive rate(73.4%–87.5%),followed by nasal swabs(53.1%–85.3%)for both severe and mild cases during the first 14 days after illness onset(d.a.o.).Viral RNA could be detected in all BALF samples collected from the severe group within 14 d.a.o.and lasted up to 46 d.a.o.Moreover,although viral RNA was negative in the upper respiratory samples,it was also positive in BALF samples in most cases from the severe group during treatment.Notably,no viral RNA was detected in BALF samples from the mild group.Despite typical ground-glass opacity observed via computed tomographic scans,no viral RNA was detected in the first three or all upper respiratory tract specimens from some COVID-19 patients.In conclusion,sputum is most sensitive for routine laboratory diagnosis of COVID-19,followed by nasal swabs.Detection of viral RNA in BALF improves diagnostic accuracy in severe COVID-19 patients. | Yang Yang Minghui Yang Jing Yuan Fuxiang Wang Zhaoqin Wang Jinxiu Li Mingxia Zhang Jinli Wei Ling Peng Gary Wong Haixia Zheng Weibo Wu Chenguang Shen Mingfeng Liao Kai Feng Jianming Li Qianting Yang Juanjuan Zhao Lei Liu Yingxia Liu | 2020 | The Innovation2020，1，3： | 1 |
| 14 | A high-density intervarietal map of the wheat genome enriched with markers derived from expressed sequence tags显示文摘 | Shulin Xue Zhengzhi Zhang Feng Lin Zhongxin Kong Yong Cao Chunjun Li Hongying Yi Mingfeng Mei Huilan Zhu Jizhong Wu Haibin Xu Dongmei Zhao Dagang Tian Caiqin Zhang Zhengqiang Ma | 2008 | Theoretical and Applied Genetics2008，，2： | 1 |
| 15 | Fingerprint analysis of Flos Carthami by pressurized CEC and LC显示文摘 | XIE Guoxiang QIU Mingfeng ZHAO Aihua | 2006 | Chromatographia2006，64，1112： | 1 |
| 16 | Optimization Study on Regenerative Organic Rankine Cycle(ORC) with Heat Source of Low-Grade Steam显示文摘Aiming at improving the performance of Organic Rankine Cycle(ORC)system with low-grade steam as heat source,this work studied and optimized the main operating parameters of the ORC system.The effects of evapo-ration temperature,superheat degree,condensation temperature and regenerator pinch temperature difference on the system performance were obtained.The optimization for the operating parameters is based on the indicators of specific net power output,waste heat pollution,cycle exergy efficiency,and total UA value(the product of overall heat transfer coefficient and heat transfer area of heat exchanger).The results show that the increase of the evaporation temperature and the superheat degree,and the decrease of the condensation temperature and regenerator pinch temperature difference can improve general system performance but lead to weaker economic performance.The optimal evaporation temperature,superheat degree,condensation temperature and regenerator pinch temperature difference are determined as 139℃,4°C,36°C and 8°C,respectively,reaching net power output of 114.73 kW,exergy efficiency of 37.10%.Besides,it is indicated that the regenerative ORC system can reach 13.6%additional net power output compared to the ORC system without the regenerator. | Zhao Wang Su Yan Mingfeng Zhu Wen Zhu Han Zhang Xiang Gou | 2022 | Energy Engineering2022，119，6： | 0 |
| 17 | Adiabaticity in state preparation for spin squeezing of large atom ensembles显示文摘Spin-squeezed state is a many-body entangled state of great interest for precision measurements.Although the absolute sensitivity at the standard quantum limit is better for a larger atom number,the greater dominance of classical noises over atom projection noise makes it harder to achieve spin squeezing.Here,we show both theoretically and experimentally that adiabatic pulse control of the pump field in state preparation is indispensable to sufficient noise suppression,which is the prerequisite for spin squeezing.This technique is generally applicable to spin-squeezing experiments involving a large ensemble and is thus of significance for quantum metrolog yapplications. | SHENCHAO JIN HAN BAO JUNLEI DUAN XINGDA LU MINGFENG WANG KAI-FENG ZHAO HENG SHEN YANHONG XIAO | 2021 | Photonics Research2021，9，11： | 0 |
| 18 | Improvement of Control System for Two 120kW RF Generators of SSC显示文摘Improvement of Control System for Two 120kW RF Generators of SSC￥YuQi;YllMingfeng;ZhaoJianmingandJiangWeimoInthepasttwoyears,... | Yu Qi Yll Mingfeng Zhao Jianming and Jiang Weimo | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 19 | Electrochromism-induced adaptive fresh air pre-handling system for building energy saving显示文摘Building fresh air supply needs to meet certain regulations and fit people’s ever-growing indoor air quality de-mand.However,fresh air handling requires huge energy consumption that goes against the goal of net-zero energy buildings.Thus,in this work,an adaptive fresh air pre-handling system is designed to reduce the cool-ing and heating loads of HVAC system.The sky-facing surface of the system uses electrochromic mechanism to manipulate the optical properties and thus make full use of solar energy(solar heating)and deep space cold source(radiative cooling)by switching between heating and cooling modes.In the cooling mode,the sky-facing surface shows a transmittance of down to zero,while the reflectance is high at 0.89 on average.In the heating mode,the electrochromic glass is highly transparent,allowing the sunlight to reach the solar heat absorber.To obtain the energy-saving potential under different climates,six cities were selected from various climate regions in China.Results show that the adaptive fresh air pre-handling system can be effective in up to 55.4%time of a year.The maximum energy-saving ratios for medium office,warehouse,and single-family house can reach up to 11.52%,26.62%,and 18.29%,respectively.In addition,the system shows multi-climate adaptability and broad application scenarios,making it a potential solution to building energy saving. | Dikai Xu Mingfeng Sheng Xinpeng Zhao Hua Qian Wenqing Liang Xiaohong Zheng Dongliang Zhao | 2024 | Energy and Built Environment2024，5，2： | 0 |
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