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| 1 | Correlation of E-selectin gene polymorphisms with risk of ischemic stroke A meta-analysis显示文摘OBJECTIVE: To investigate the association of E-selectin S128R polymorphisms with ischemic stroke. DATA SOURCES: A computer-based online search was conducted in PubMed, Elsevier, Ovid Database, the China National Knowledge Infrastructure, and Wanfang Database between January 1998 and December 2010. STUDY SELECTION: Case-controlled studies addressing the association of the E-selectin polymorphism and ischemic stroke were included in this review. The genotype distribution complied with the Hardy-Weinberg genetic equilibrium. The included reports were evaluated by two authors for strict quality screening. Meta-analysis software, REVMAN 5.1, was used to investigate heterogeneity, pooled odds ratio (OR) and 95% confidence interval (CI) in individual studies. MAIN OUTCOME MEASURES: Genotype and allele distributions at the E-selectin S128R site. RESULTS: Six case-controlled studies were included after screening and application of inclusion and exclusion criteria. There was no heterogeneity in the genotype and allele frequencies, and no publication bias was found. Meta-analysis of the pooled data showed that the OR value of the (AC+CC)/AA genotype was 1.93 (95% CI: 1.55-2.41, Z = 5.80, P < 0.000 01), and the OR for the C/A allele was 1.80 (95% CI: 1.47-2.22, Z = 5.59, P < 0.000 01) in the ischemic stroke group, compared with control group. Results of pooled data in Chinese subjects showed that the OR value of (AC+CC)/AA was 2.36 (95% CI: 1.68-3.31, Z = 4.99, P < 0.000 01), and the OR value of the C/A allele was 2.25 (95% CI: 1.63-3.12, Z = 4.89, P < 0.000 01). CONCLUSION: Polymorphism of E-selectin S128R was significantly associated with susceptibility to ischemic stroke; the AC and CC genotypes as well as the C allele may be factors associated with susceptibility to ischemic stroke. | Qingli Sun Yu Fu Aping Sun Yanhong Shou Mei Zheng Xiaogang Li Dongsheng Fan | 2011 | Neural Regeneration Research2011，6，22： | 46 |
| 2 | Cell–cell contact with proinflammatory macrophages enhances the immunotherapeutic effect of mesenchymal stem cells in two abortion models显示文摘Mesenchymal stem cells(MSCs),which are pluripotent cells with immunomodulatory properties,have been considered good candidates for the therapy of several immune disorders,such as inflammatory bowel diseases,concanavalin A-induced liver injury,and graft-versus-host disease.The embryo is a natural allograft to the maternal immune system.A successful pregnancy depends on the timely extinction of the inflammatory response induced by embryo implantation,followed by the switch to a tolerant immune microenvironment in both the uterus and the system.Excessive infiltration of immune cells and serious inflammatory responses are triggers for embryo rejection,which results in miscarriage.Here,we demonstrated that adoptive transfer of MSCs could prevent fetal loss in a lipopolysaccharide(LPS)-induced abortion model and immune response-mediated spontaneous abortion model.The immunosuppressive MSCs alleviated excessive inflammation by inhibiting CD4+T cell proliferation and promoting the decidual macrophage switch to M2 in a tumor necrosis factor-stimulated gene-6(TSG-6)-dependent manner.Cell-tocell contact with proinflammatory macrophages increased the TSG-6 production by the MSCs,thereby enhancing the suppressive regulation of T cells and macrophages.Moreover,proinflammatory macrophages in contact with the MSCs upregulated the expression of CD200 on the stem cells and facilitated the reprogramming of macrophages towards an anti-inflammatory skew through the interaction of CD200 with CD200R on proinflammatory macrophages.Therefore,the results demonstrate that a TSG-6-mediated paracrine effect,reinforced by cell-to-cell contact between MSCs and proinflammatory macrophages,is involved in the mechanism of MSC-mediated abortion relief through the induction of immune tolerance.Our study also indicates the potential application of MSCs in clinical recurrent miscarriages. | Yanhong Li Di Zhang Ling Xu Lin Dong Ji Zheng Yikong Lin Jiefang Huang Yanyun Zhang Yu Tao Xingxing Zang Dajin Li Meirong Du | 2019 | Cellular & Molecular Immunology2019，16，12： | 23 |
| 3 | Bifurcation analysis for Hindmarsh-Rose neuronal model with time-delayed feedback control and application to chaos control显示文摘This paper is concerned with bifurcations and chaos control of the Hindmarsh-Rose(HR)neuronal model with the time-delayed feedback control.By stability and bifurcation analysis,we find that the excitable neuron can emit spikes via the subcritical Hopf bifurcation,and exhibits periodic or chaotic spiking/bursting behaviors with the increase of external current.For the purpose of control of chaos,we adopt the time-delayed feedback control,and convert chaos control to the Hopf bifurcation of the delayed feedback system.Then the analytical conditions under which the Hopf bifurcation occurs are given with an explicit formula.Based on this,we show the Hopf bifurcation curves in the two-parameter plane.Finally,some numerical simulations are carried out to support the theoretical results.It is shown that by appropriate choice of feedback gain and time delay,the chaotic orbit can be controlled to be stable.The adopted method in this paper is general and can be applied to other neuronal models.It may help us better understand the bifurcation mechanisms of neural behaviors. | WANG HaiXia WANG QingYun ZHENG YanHong | 2014 | Science China(Technological Sciences)2014，57，5： | 18 |
| 4 | Dynamics of firing patterns,synchronization and resonances in neuronal electrical activities:experiments and analysis显示文摘在 neuronal 的动力学的试验性、理论的学习的最近的进展电的开火活动被考察。第一, neuronal 的一些试验性的现象不规则的开火模式,特别混乱、随机的开火的模式,被介绍,并且实际非线性的时间分析方法被介绍及时区分确定、随机的机制系列。第二,也就是,在一个单个神经原的电的开火的活动的动力学被担心为为发射模式的转变的各种各样的爆炸模式,一个参数或二参数的分叉分析的分类和机制的快慢动力学分析,和发射活动的随机的动力学(随机并且连贯回声,多重的整数和另外的开火的模式由噪音导致了,等等)。第三,有电、化学的触处的联合神经原的同步的不同类型被讨论。因为噪音和时间延期在神经系统是不可避免的,它被发现延期可以导致或提高发射联合神经原的模式的同步和变化的那噪音和时间。在联合 neuronal 网络的导致噪音的回声和空间与时间的模式也被表明。最后,一些前景为未来研究被介绍。在后果,非线性的动力学的想法和方法具有在动态进程的探索和神经系统的生理的函数的大意义。 | Qishao Lu Huaguang Gu Zhuoqin Yang Xia Shi Lixia Duan Yanhong Zheng | 2008 | Acta Mechanica Sinica2008，24，6： | 14 |
| 5 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 6 | Comparison of cancer incidence and mortality in three GDP per capita levels in China, 2013显示文摘Objective:In this research,the patterns of cancer incidence and mortality in areas with different gross domestic product per capita(GDPPC)levels in China were explored,using data from population-based cancer registries in 2013,collected by the National Central Cancer Registry(NCCR).Methods:Data from 255 cancer registries were qualified and included in this analysis.Based on the GDPPC data of 2014,cities/counties were divided into 3 levels:high-,middle-and low-GDPPC areas,with 40,000 and 80,000 RMB per year as cut points.We calculated cancer incidences and mortalities in these three levels,stratified by gender and age group.The national population of the Fifth Census in 2000 and Segi’s population were applied for age-standardized rates.Results:The crude incidence and mortality rates as well as age-standardized incidence rate(ASIR)showed positive associations with GDPPC level.The age-standardized mortality rate(ASMR)nevertheless showed a negative association with GDPPC level.The ASMR in high-,middle-and low-GDPPC areas was 103.12/100,000,112.49/100,000 and 117.43/100,000,respectively.Lung cancer was by far the most common cancer in all three GDPPC levels.It was also the leading cause of cancer death,regardless of gender and GDPPC level.Negative associations with GDPPC level were found for the ASIRs of lung,stomach,esophageal and liver cancer,whereas colorectal and breast cancer showed positive associations.Except for breast cancer,the ASMRs of the other five cancers were always higher in middle-and low-GDPPC areas than in high-GDPPC areas.Conclusions:The economic development is one of the main factors of the heavy cancer burden on Chinese population.It would be reasonable to implement cancer control strategies referring to the local GDPPC level. | Zhixun Yang Rongshou Zheng Siwei Zhang Hongmei Zeng Changfa Xia He Li Li Wang Yanhong Wang Wanqing Chen | 2017 | Chinese Journal of Cancer Research2017，29，5： | 13 |
| 7 | Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis显示文摘 | Wenling Zhang Zhaoyang Zeng Yanhong Zhou Wei Xiong Songqing Fan Lan Xiao Donghai Huang Zheng Li Dan Li Minghua Wu Xiaoling Li Shourong Shen Rong Wang Li Cao Ke Tang Guiyuan Li | 2009 | Acta Biochimica et Biophysica Sinica2009，41，5： | 11 |
| 8 | Highly efficient solution-processed CZTSSe solar cells based on a convenient sodium-incorporated post-treatment method显示文摘In CZTSSe solar cells,a simple sodium-incorporation post-treatment method toward solution-processed Cu2Zn Sn S4precursor films is presented in this work.An ultrathin NaCl film is deposited on Cu2Zn Sn S4precursor films by spin-coating NaCl solution.In subsequent selenization process,the introduction of Na Cl is found to be benefacial for the formation of Cu2-xSe,which can further facilitate the element transportation,leading to dense and smooth CZTSSe films with large grains and less impurity Cu2Sn(S,Se)3phase.SIMS depth profiles confirm the gradient distribution of the sodium element in Na-doped absorbers.Photoluminescence spectra show that the introduction of appropriate sodium into the absorber can inhibit the band tail states.As high as 11.18% of power conversion efficiency(PCE)is achieved for the device treated with 5 mg mL^-1 NaCl solution,and an average efficiency of Na-doped devices is 10.71%,13%higher than that of the control groups(9.45%).Besides,the depletion width and the charge recombination lifetime can also have regular variation with sodium treatment.This work offers an easy modification method for high-quality Na-doped CZTSSe films and high-performance devices,in the meantime,it can also help to further understand the effects of sodium in CZTSSe solar cells. | Biwen Duan Linbao Guo Qing Yu Jiangjian Shi Huijue Wu Yanhong Luo Dongmei Li Sixin Wu Zhi Zheng Qingbo Meng | 2020 | Journal of Energy Chemistry2020，29，1： | 8 |
| 9 | Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration显示文摘Hyperhomocysteinemia (HHcy ) 由增加增长并且在 T 房间刺激 cytokine 分泌物加速动脉粥样硬化。然而, homocysteine (Hcy ) 是否调停了 T 房间激活与新陈代谢的 reprogramming 被联系是不清楚的。这里,我们的在里面 vivo 并且在研究显示出的 vitro,在老鼠的那刺激 Hcy 的脾的 T 房间激活被 mitochondrial 的增加的层次伴随反应的氧种类(ROS ) 和钙, mitochondrial 团和呼吸。禁止 mitochondrial ROS 生产和钙信号或堵住 mitochondrial 呼吸大部分弄钝导致 Hcy 的 T 房间干扰素(IFN-) 分泌物和增长。Hcy 也提高了 endoplasmic 蜂窝胃(嗯) 在 T 房间的应力,和抑制嗯有 4-phenylbutyric 酸的应力堵住了导致 Hcy 的 T 房间激活。机械学地, Hcy 增加了联合,并且解开的嗯线粒体由微导管禁止者 nocodazole 的嗯线粒体在 T 房间稀释了刺激 Hcy 的 mitochondrial reprogramming, IFN- 分泌物和增长,建议那并排嗯并且线粒体为支持 Hcy 的 mitochondrial 被要求功能和 T 房间激活。在结论, Hcy 由增加联合并且调整新陈代谢的 reprogramming 的嗯线粒体支持 T 房间激活。 | Juan Feng Silin Lu Yanhong Ding Ming Zheng Xian Wang | 2016 | Protein & Cell2016，7，6： | 6 |
| 10 | Investigating changes in lake systems in the south-central Tibetan Plateau with multi-source remote sensing显示文摘在西藏的高原的湖被认为应答者敏感到全球温暖。在象表面区域和水水平那样的湖系统的物理特征的变化在理解地区性的回答到在最近的十年的全球温暖是很有用的。在这研究,多来源遥感数据被用来在过去的十年在西藏的高原的南方中央的部分检索表面区域和五个内陆湖的水水平时间系列。在水水平和湖的表面区域的变化被调查。结果证明水三铺平湖(美洲狮 Yumco,芋头公司, Zhari Namco ) 增加与扩展表面区域,当水另外的二个湖铺平时(Paiku 公司, Mapam Yumco ) 掉落,与缩小区域。湖的水层次作为与 1976-1999 相比在 2000-2012 经历了显著变化。空间地,在西藏的高原的南部的穗定位的湖在水水平变化显示出一致性,它与在中央西藏的高原的湖不同。 | WU Yanhong ZHANG Xin ZHENG Hongxing LI Junsheng WANG Zhiying | 2017 | Journal of Geographical Sciences2017，27，3： | 5 |
| 11 | Compositions of aliphatic des-A-triterpenes in the Hani peat deposit,Northeast China and its biological significance显示文摘Aliphatic des-A-triterpenes,the degradation products of pentacyclic triterpenes have been tentatively assigned in samples taken from a 963-cm-thick peat sequence from the Hani region of Northeast China using gas chromatography-mass spectrometry(GC-MS)in order to understand and identify these des-A-triterpenes response to climate and ecology.The study indicates that aliphatic des-A-triterpenes are abundant in the Hani peat bog.The high relative abundance of the total des-A-triterpenes mainly occurs at the Holocene periods and is corresponding to the low sedimentation rate.The mechanism of des-A-triterpenes accumulation is not consistent with the previous studies.It is proposed that the biological community is also one influence factor.The obvious stage variations of the total des-A-triterpenes in the whole sequence reveal the different biological(microbes and plants) processes and responses,possibly revealing the four large replacements of biological community and functional composition in the swamp environment over the 16000 cal a BP.The low total des-A-triterpenes values occur at about 10200,8700,7700,6600,4480-3940 and 3040 cal a BP,reflecting the multiple millennial micro-environment oscillations under the macro-environment of the swamp during the Holocene.The ratios of diene and monoene des-A-triterpenes(DT/MT),des-A-lupane and diene and monoene des-A-triterpenes(DL/(DT+MT)),ratios ofindividual compounds exhibit vertical opposite to the total des-A-triterpenes. Namely,these ratios are high during the last deglaciation and late Holocene whereas they are low at other periods,indicating different compounds have different responses to micro-environment and microbial activities.This study discusses the diversity of biological community and biological functional composition response to micro-environment,which not only provides the complement in Northeast China,but also bears important fundamental information for the implication to ecological environment in the future. | ZHENG YanHong ZHOU WeiJian LIU Zhao CHEN QingMin YU XueFeng LIU XiaoMin | 2010 | Chinese Science Bulletin2010，55，21： | 5 |
| 12 | Diversity of culturable heterotrophic bacteria from the Mariana Trench and their ability to degrade macromolecules显示文摘The Mariana Trench is the deepest location on earth and harbors unique microbial communities as evidenced by 16S rRNA gene amplicon and metagenomic sequencing.Obtaining culturable microorganisms from the Mariana Trench will contribute to a further understanding of hadal biogeochemical processes and act as a unique microbial reservoir with potential applications.Here,825 bacterial strains,identified by 16S rRNA gene sequencing,were isolated from 12 water depths(0-10,400 m)of the Mariana Trench with 2216E and R2A media at 4℃ or 28℃ on four cruises during 2015-2017.These bacteria belong to four phyla,nine classes,27 orders,45 families and 108 genera.Alphaproteobacteria,Gammaproteobacteria,Actinobacteria_c,Bacilli and Flavobacteriia were the most abundant classes,accounting for 37.9%,33.0%,11.8%,8.6%and 8.0%of the total bacterial isolates,respectively.2216E and R2A media were found to have a better selectivity to Bacilli and Flavobacteriia,respectively.Fifty strains were potential novel bacterial species with a 16S rRNA gene similarity<98.65%,and a higher percentage of novel strains were obtained from R2A than 2216E medium.Additionally,301(150 species)out of 354 strains(178 species)selected from each depth could degrade at least one of the ten kinds of macromolecules tested.These results indicate that there is a high diversity of culturable bacteria in the Mariana Trench and they can produce a variety of extracellular enzymes.Our study provides a valuable resource of microorganisms for investigating their biogeochemical roles in the Mariana Trench and for industrial applications. | Xiuxiu Zhao Jiwen Liu Shun Zhou Yanfen Zheng Yanhong Wu Kazuhiro Kogure Xiao-Hua Zhang | 2020 | Marine Life Science & Technology2020，2，2： | 5 |
| 13 | Induction of Tetraploid Male Sterile Tagetes erecta by Colchicine Treatment and Its Application for Interspecific Hybridization显示文摘Tagetes erecta is an annual multifunctional plant which can be cultivated under a broad range of climatic conditions. Polyploidization and interspecific hybridization are applied to facilitate breeding cultivars of T. erecta with improved ornamental qualities. Colchicine treatment to the germinating seeds was proved to be a useful tool for chromosome doubling of the male sterile two-type line ‘M525AB', with the resulting frequency of polyploid seedlings ranging from 88.89%(following 0.05% w/v colchicine applied for a 3–6 h exposure period) to a maximum of100.00%(following 0.1% for 3–6 h, or 0.2% for 3 h). Morphological observation, stomatal size and density analysis, flow cytometric analysis and chromosome counting were conducted to identify the tetraploid plants. Distinctive morphological changes were observed in a notable proportion of polyploid plants. The colchicine-treated polyploid T. erecta plants showed dwarfed and more robust growth, thicker, larger and greener leaves, larger inflorescences and florets. The mutant plants identified through morphological observation all aligned as polyploid plants, thus morphological observation could be an effective method for the detection of polyploidy. The polyploid plants had significant larger stomata size over the abaxial leaf surface, whereas the density of stomata distribution was remarkably reduced. The survival rate of tetraploid cuttings(i.e. 38%)was greatly reduced compared to that of diploid plants. The fertility of tetraploid plants was also decreased, as shown by cross-pollination yields.Interspecific hybridizations between colchicine-induced tetraploid plants of a male sterile T. erecta line and the naturally tetraploid fully fertile Tagetes patula species resulted in hybrid progeny. Most of these hybrids displayed the dwarfed growth stature and compact, larger-flower morphology which is the typical ideotype of herbaceous flowers. Thus, polyploidization may be employed effectively as a means to facilitate interspecific hybridization, thereby contributing significantly to the improvement of quantitative traits of Tagetes spp. | HE Yanhong SUN Yalin ZHENG Riru AI Ye CAO Zhe BAO Manzhu | 2016 | Horticultural Plant Journal2016，2，5： | 5 |
| 14 | Improving control effects of absence seizures using single-pulse alternately resetting stimulation (SARS) of corticothalamic circuit显示文摘Presently,we develop a simplified corticothalamic(SCT)model and propose a single-pulse alternately resetting stimulation(SARS)with sequentially applying anodic(A,“+”)or cathodic(C,“−”)phase pulses to the thalamic reticular(RE)nuclei,thalamus-cortex(TC)relay nuclei,and cortical excitatory(EX)neurons,respectively.Abatement effects of ACC-SARS of RE,TC,and EX for the 2 Hz-4 Hz spike and wave discharges(SWD)of absence seizures are then concerned.The m∶n on-off ACC-SARS protocol is shown to effectively reduce the SWD with the least current consumption.In particular,when its frequency is out of the 2 Hz-4 Hz SWD dominant rhythm,the desired seizure abatements can be obtained,which can be further improved by our proposed directional steering(DS)stimulation.The dynamical explanations for the SARS induced seizure abatements are lastly given by calculating the averaged mean firing rate(AMFR)of neurons and triggering averaged mean firing rates(TAMFRs)of 2 Hz-4 Hz SWD. | Denggui FAN Yanhong ZHENG Zecheng YANG Qingyun WANG | 2020 | Applied Mathematics and Mechanics(English Edition)2020，41，9： | 4 |
| 15 | High-efficiency extraction synthesis for high-purity copper nanowires and their applications in flexible transparent electrodes显示文摘Copper nanowires(Cu NWs)are considered an excellent alternative to indium tin oxide(ITO)in flexible transparency electrodes(FTEs).However,the mixed particles and surface oxidation of Cu NWs degrade the transmittance and conductivity of the electrodes.Therefore,highly purified Cu NWs without oxidation are vital for high-performance FTEs.Herein,a facile and effective purification process is introduced to purify Cu NWs in a water and n-hexane system,which takes advantage of the differences in hydrophilicity between Cu NWs and Cu NPs caused by their different adsorption affinities to octadecylamine(ODA).At the same sheet resistance,the transmittance of the purified Cu NW-based FTEs improved approximately 2%compared to that of non-purified Cu NW-based FTEs.Immersion of the electrode in glacial acetic acid removed the surface organics and oxides.After only 40 s of treatment,the sheet resistance dramatically decreased from 10^5 Ohm/sq to 31 Ohm/sq with a transmittance of 85%.In addition,the Cu NW-based FTE conductors showed excellent flexibility(remaining stable after 1000 bending cycles).The Cu NW-based FTEs were further applied to fabricate a flexible transparent heater.At a voltage of 10 V,the temperature of the heater reached 73℃,demonstrating the potential applications of this material in various fields. | He Zhang Shang Wang Yanhong Tian Jiayue Wen Chunjin Hang Zhen Zheng Yilong Huang Su Ding Chenxi Wang | 2020 | Nano Materials Science2020，2，2： | 4 |
| 16 | Green Synthesis of Nitrogen-to-Ammonia Fixation: Past, Present, and Future显示文摘The nitrogen(N2)-to-ammonia(NH3)fixation driven by renewable energy has an attractive prospect to relieve the global warming and reduce the consumption of fossil fuels.Ideally,photocatalytic,electrochemical,and photoelectrochemical approaches are developed as the next-generation NH3 synthesis technologies to substitute the Haber–Bosch method.However,the NH3 yield rate of nitrogen reduction reaction(NRR)by green approaches is extremely low,resulting in the current dilemma of NRR and contamination issues.Thus,in this mini review,the past advances on the sustainable NRR are briefly summarized in the three aspects as follows:the selectivity and adjustment of various catalysts,the type of electrolyte/solvent system,and the investigation of reaction conditions.Subsequently,the recent critical activities in the area of sustainable NH3 synthesis are analyzed and discussed deeply,and a perspective for rational and healthy development of this area is provided positively。 | Jianyun Zheng Li Jiang Yanhong Lyu San Ping Jiang Shuangyin Wang | 2022 | Energy & Environmental Materials2022，5，2： | 3 |
| 17 | Exceptional preservation of soft tissue in a new specimen of Eoconfuciusornis and its biological implications显示文摘We report on an exceptional specimen of Eoconfuciusornis preserving rare soft-tissue traces of the ovary and wing. Ovarian follicles preserve a greater hierarchy than observed in Jeholornis and enantiornithines,suggesting confuciusornithiforms evolved higher rates of yolk deposition in parallel with the neornithine lineage. The preserved soft tissues of the wing indicate the presence of a propatagium and postpatagium,whereas an alular patagium is absent. Preserved remnants of the internal support network of the propatagium bear remarkable similarity to that of living birds. Soft tissue suggests the confuciusornithiform propatagium could maintain a cambered profile and generate lift. The feathers of the wing preserve remnants of their original patterning; however, this is not strongly reflected by observable differences under scanning electron microscopy(SEM). The tail plumage lacks elongate rectrices, suggesting that the earliest known confuciusornithiforms were sexually dimorphic in their plumage. | Xiaoting Zheng Jingmai K. O'Connor Xiaoli Wang Yanhong Pan Yan Wang Min Wang Zhonghe Zhou | 2017 | National Science Review2017，4，3： | 3 |
| 18 | Microstructural Evolution of a Ni-base Alloy DZ468 Joint Bonded with a New Co-base Filler显示文摘Ni-base alloy DZ468 has been joined by transient liquid phase bonding technique with a newly developed Co-based filler.The microstructures of the Co-base filler and the joint,the effects of heat treatment on microstructure and hardness of the joint have been investigated by various experimental methods.Results show that the Co-base filler consists ofγ,M_2B,M_5B_3 and M_(23)B_6 phases.Because of the interdiffusion between the base metal and the filler,y,MC,M_5B_3 and M_(23)B_6 phases are formed in the bonding zone.And localized liquidation of substrate occurs in the diffusion affected zone,with MC and M_3B_2 precipitating in this area.During heat treatment,the volume of the intermetallic phases in the bonding zone resulting from incomplete isothermal solidification decreases obviously.On the contrary,the width of the diffusion affected zone increases at the solution stage and subsequently decreases at the aging stages. | Yanhong Jing Zhi Zheng Enze Liu Yi Guo | 2014 | Journal of Materials Science & Technology2014，30，5： | 3 |
| 19 | CPTA treatment reveals potential transcription factors associated with carotenoid metabolism in flowers of Osmanthus fragrans显示文摘Osmanthus fragrans is one of the top ten traditional flowers in China.It is divided into three different groups according to its color.α-Carotene and β-carotene are the main determinants to distinguish the color differences between three groups.However,the dominant genes and transcription factors involved in carotenoid metabolism remain unclear.CPTA treatment(0.7mmol·L−1)remarkably promoted lycopene,α-carotene and β-carotene contents in flowers.Transcriptome sequencing analysis revealed that CPTA treatment could trigger chain reactions in carotenoid metabolism pathway genes.Four up-regulated and 10 down-regulated transcription factors which have close association with carotenoid variation were significantly induced by CPTA treatment.The up-regulated TFs such as MYB43,MYB123,HSF,were further subjected to transcript expression determination in different cultivars with drastic colors.Among them,transcript expression of four up-regulated TFs coincided with the carotenoid accumulation in different cultivars.We selected up-regulated OfMYB43 to verify its function,which is related to stress tolerance and transcriptional regulation.Transient overexpression of OfMYB43 in O.fragrans flowers showed that it could remarkably promote the expression of PDS,ZISO,LCYE and CCD4,leading to increased accumulation of β-branch carotenoids.OfMYB43 was a potential positive regulator of carotenoid biosynthesis in O.fragrans flowers.This study provides insight into the molecular mechanism of carotenoid metabolism in O.fragrans. | Wan Xi Yanhong He Linlin Zhu Shiyang Hu Shuyi Xiong Yi Zhang Jingjing Zou Hongguo Chen Caiyun Wang Riru Zheng | 2021 | Horticultural Plant Journal2021，7，5： | 3 |
| 20 | Comparative transcriptome analysis of different heat stress responses between self-root grafting line and heterogeneous grafting line in rose显示文摘Rose is sensitive to high temperature which will make the rose go into a semi-dormancy state.Grafting is an excellent way to enhance rose heat tolerance.Here,heat-tolerant Rosa multiflora‘Huanong Wuci 1'(W)and heat-sensitive Rosa chinensis‘Old Blush’(X)were selected as experimental materials.The RNA-seq technique was used to investigate the transcriptomes of self-root grafting line(XX0),heterogeneous grafting line(XW0),self-root grafting line under 6 h heat stress(XX6),and heterogeneous grafting line under 6 h heat stress(XW6).Under high temperature stress,multiple signaling pathways were activated,moreover,a large number of transcription factors and functional genes were induced,especially the HSFs and HSPs with remarkably upregulated expression levels.The GO analysis showed that the differences in the expressions of the genes related to fatty acids and carbohydrates were observed between self-root grafting line and heterogeneous grafting line.In addition,14 P450s were differentially expressed,and one lectin gene was up-regulated in XW0 vs XW6,but down-regulated in XX0 vs XX6.Considering physiological and biochemical traits such as relative electrolyte leakage,SOD activity,proline,and total soluble sugars,DEGs involved in these processes may be key factors to resist high temperature.The present study provides an insight into the complex mechanism underlying grafting in response to heat stress.Our results indicate that grafting is an effective way to improve rose heat resistance. | Wenquan Qi Chunling Zhang Wenjing Wang Zhe Cao Song Li Hang Li Wan Zhu Yongqi Huang Manzhu Bao Yanhong He Riru Zheng | 2021 | Horticultural Plant Journal2021，7，3： | 3 |
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