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| 1 | Crystal structures and thermal decomposition kinetics of lanthanide complexes with 3,4,5-trimethoxybenzoic acid and 1,10-phenanthroline显示文摘A series of lanthanide complexes with the 3,4,5-trimethoxybenzoic acid(3,4,5-tmoba) and 1,10-phenanthroline(phen),[Ln(3,4,5-tmoba) 3 phen] 2(Ln = Pr(1),Nd(2) and Ho(3)),have been synthesized and characterized by a series of techniques including elemental analysis,IR spectra,X-ray crystallography and TG/DSC-FTIR technology.The three complexes have two kinds of coordination modes,in which the Pr 3+ and Nd 3+ cations are nine-coordinated and the Ho 3+ cation is eight-coordinated.The three-dimensional IR accumulation spectra of gaseous products for complexes 1-3 were analyzed and the gaseous products were identified by the typical IR spectra obtained from the 3D surface graphs.Meanwhile,we obtained the activation energy E of the first steps of complexes 1-3 by the integral isoconversional non-linear(NL-INT) method and discussed the non-isothermal kinetics of complexes 1-3 using the Malek method.Finally,SB(m,n) was defined as the kinetic method of the first-step thermal decomposition.The thermodynamic parameters △G≠,△H≠ and △S≠ of activation at the peak temperature were also calculated. | TANG Kun ZHANG JianJun REN Ning ZHENG JunRu LIU JingYu WU KeZhong | 2012 | Science China Chemistry2012，55，7： | 6 |
| 2 | Numerical simulation of the effect of lower positive charge region in thunderstorms on different types of lightning显示文摘Combined with the existing stochastic lightning parameterization scheme, a classic tripole charge structure in thunderstorms is assumed in the paper, and then 2-dimensional fine-resolution lighting discharge simulations are performed to quantitatively investigate the effect of lower positive charge(LPC) on different types of lightning. The results show:(1) The LPC plays a key role in generating negative cloud-to-ground(CG) flashes and inverted intra-cloud(IC) lightning, and with the increase of charge density or distribution range of LPC region, lightning type changes from positive polarity IC lightning to negative CG flashes and then to inverted IC lightning.(2) Relative to distribution range of charge regions, the magnitude of charge density of the LPC region plays a dominant role in lightning type. Only when the maximal charge density value of LPC region is within a certain range, can negative CG flashes occur, and the occurrence probability is relatively fixed.(3) In this range, the charge density and distribution range of LPC region jointly determine the occurrence of negative CG flashes, which has a linear boundary with the trigger condition of IC lightning.(4) The common effect of charge density and distribution range of the LPC region is to change the distribution of positive potential well of bottom part of thunderstorms, and inverted IC lightning occurs when the initial reference potential is close to 0 MV, and negative CG flashes occur when the initial reference potential is far less than 0 MV. | TAN YongBo LIANG ZhongWu SHI Zheng ZHU JunRu GUO XiuFeng | 2014 | Science China Earth Sciences2014，57，9： | 5 |
| 3 | Determining the optimal time for bortezomib-based induction chemotherapy followed by autologous hematopoietic stem cell transplant in the treatment of multiple myeloma显示文摘In our study, we determined the efficacy of bortezomib-based induction therapy followed by autologous stem cell transplant (ASCT) in newly diagnosed and relapsed/refractory (R/R) multiple myeloma (MM) patients and compared the advantages of early versus late transplant. We used a retrospective analysis to examine 62 patients, including 46 cases of newly diagnosed MM (early transplant group) and 16 cases of relapsed/refractory MM (late transplant group). All of these patients received bortezomib-based induction therapy followed by ASCT. The efficacy and side effects of the treatment regimen were analyzed. Patients' overall survival (OS) and progression-free survival (PFS) times were determined. The ratio of complete remission to near-complete remission (CR/nCR) was 69.5% versus 56.2% (P=0.361), respectively, for the early transplant group versus the late transplant group, respectively, after receiving bortezomib-based induction therapy; the overall response rates of the two group were 91.3% and 81.2%, respectively (P=0.369). After receiving ASCT, the CR/nCR of the two groups increased to 84.8% and 81.3%, respectively. The median time required for neutrophil engraftment of the early transplant group and the late transplant group was 11 and 14.5 days, respectively (P=0.003); the median time required for platelet engraftment was 13 and 21.5 days (P=0.031), respectively. There were no significant differences in the toxic side effects observed during induction therapy and ASCT between the two groups. The OS of the two groups was not statistically different (P=0.058). The PFS of the early transplant group and the late transplant group was 41.6 and 26.5 months, respectively (P=0.008). Multivariate analysis demonstrated that the time of receiving ASCT, the types of M protein, and the International Staging System (ISS) stage were all independent factors that influenced PFS. In conclusion, patients in a suitable condition for ASCT should be recommended to have an early ASCT immediately after diagnosis. | Junru Liu Juan Li Beihui Huang Dong Zheng Mei Chen Zhenhai Zhou Duorong Xu Waiyi Zou | 2013 | Chinese Journal of Cancer Research2013，25，2： | 4 |
| 4 | High prevalence of hepatitis B virus infection in multiple myeloma显示文摘 | Beihui Huang Juan Li Zhenhai Zhou Dong Zheng Junru Liu Mei Chen | 2012 | Leukemia & Lymphoma2012，，： | 2 |
| 5 | Functionalized Fiber-Based Strain Sensors:Pathway to Next-Generation Wearable Electronics显示文摘Wearable strain sensors are arousing increasing research interests in recent years on account of their potentials in motion detection,personal and public healthcare,future entertainment,man-machine interaction,artificial intelligence,and so forth.Much research has focused on fiber-based sensors due to the appealing performance of fibers,including processing flexibility,wearing comfortability,outstanding lifetime and serviceability,low-cost and large-scale capacity.Herein,we review the latest advances in functionalization and device fabrication of fiber materials toward applications in fiber-based wearable strain sensors.We describe the approaches for preparing conductive fibers such as spinning,surface modification,and structural transformation.We also introduce the fabrication and sensing mechanisms of state-of-the-art sensors and analyze their merits and demerits.The applications toward motion detection,healthcare,man-machine interaction,future entertainment,and multifunctional sensing are summarized with typical examples.We finally critically analyze tough challenges and future remarks of fiber-based strain sensors,aiming to implement them in real applications. | Zekun Liu Tianxue Zhu Junru Wang Zijian Zheng Yi Li Jiashen Li Yuekun Lai | 2022 | Nano-Micro Letters2022，14，4： | 2 |
| 6 | Everolimus enhances the cytotoxicity of bendamustine in multiple myeloma cells through a network of pro-apoptotic and cell-cycle-progression regulatory proteins显示文摘Bendamustine 是有在治疗的一些功效的一个 bifunctional alkylating 代理人最新诊断了并且 relapsed/refractorymultiple 骨髓瘤(公里) 。Everolimus, rapamycin (mTOR ) 的一个哺乳动物的目标禁止者,是在许多癌症有功效的另外的答应 chemotherapeuticagent。我们调查了个人和 combinational 在公里房间线(RPMI8226 和 MM1.S ) 和主要公里房间的 thesedrugs 的细胞毒素的效果。我们的结果表明了这些药的 synergistic 效果,它为 p53-wild-type 和 p-53-deleted 公里房间是有效的,但是在从 healthydonor 的 mononuclear 房间是最小的。有二个代理人的联合治疗禁止了增长并且作为 assessedby Annexin-V/PI 染色, caspase-3 降级,和 PARP 劈开支持了 cytotoxicity 和 apoptosis。房间死亡与 thepro-apoptotic 蛋白质 Bax 的起来规定和 anti-apoptotic 蛋白质 Mcl-1 和 survivin 的下面规定被联系。联合 drugtreatment 也在 mTOR 的下游的目标蛋白质的层次支持了减少小径, p70s6k,和 4EBP-1,以及在 MM1.S 房间的肿瘤 suppressor 蛋白质 p53 的 phosphorylation 的水平的增加。p21 也是有二药的 down-regulatedupon 治疗,建议通过房间周期拘捕的版本的促进感受性的机制。我们的 resultsdemonstrate 可以贡献 everolimus 和 bendamustine 的 synergistic cytotoxicity,并且为公里的组合处理为申请向一个基本原理提供 alkylating 代理人和 mTOR 禁止者 infuture 的规章的因素的一个网络临床的实践。 | Bo Lu Juan Li Jingxuan Pan Beihui Huang Junru Liu Dong Zheng | 2013 | Acta Biochimica et Biophysica Sinica2013，45，8： | 1 |
| 7 | Hepatitis B virus reactivation in patients with multiple myeloma receiving bortezomib-containing regimens followed by autologous stem cell transplant显示文摘 | Juan Li Beihui Huang Ying Li Dong Zheng Zhenhai Zhou Junru Liu | 2015 | Leukemia & Lymphoma2015，，6： | 1 |
| 8 | A Priority-aware Frequency Domain Polling MAC Protocol for OFDMA-based Networks in Cyber-physical Systems显示文摘Wireless networking in cyber-physical systems(CPSs) is characteristically different from traditional wireless systems due to the harsh radio frequency environment and applications that impose high real-time and reliability constraints.One of the fundamental considerations for enabling CPS networks is the medium access control protocol. To this end, this paper proposes a novel priority-aware frequency domain polling medium access control(MAC) protocol, which takes advantage of an orthogonal frequency-division multiple access(OFDMA)physical layer to achieve instantaneous priority-aware polling.Based on the polling result, the proposed work then optimizes the resource allocation of the OFDMA network to further improve the data reliability. Due to the non-polynomial-complete nature of the OFDMA resource allocation, we propose two heuristic rules,based on which an efficient solution algorithm to the OFDMA resource allocation problem is designed. Simulation results show that the reliability performance of CPS networks is significantly improved because of this work. | Meng Zheng Junru Lin Wei Liang Haibin Yu | 2015 | IEEE/CAA Journal of Automatica Sinica2015，2，4： | 1 |
| 9 | Hepatitis B virus infection status is an independent risk factor for multiple myeloma patients after autologous hematopoietic stem cell transplantation显示文摘 | Juan Li Junru Liu Beihui Huang Dong Zheng Mei Chen Zhenhai Zhou Duorong Xu Waiyi Zou | 2013 | Tumor Biology2013，，3： | 1 |
| 10 | Recombinant Soluble Transforming Growth Factor β Type II Receptor Ameliorates Radiation Enteropathy in Mice显示文摘 | Huaien Zheng* Junru Wang* Victor E. Koteliansky? Philip J. Gotwals? Martin Hauer-Jensen* | 2000 | Gastroenterology2000，，5： | 1 |
| 11 | Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device显示文摘 | Long Meng Feiyan Cai Qiaofeng Jin Lili Niu Chunxiang Jiang Zhanhui Wang Junru Wu Hairong Zheng | 2011 | Sensors & Actuators: B Chemical2011，，1： | 1 |
| 12 | Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation显示文摘 | Jumei Shi Junru Wang Huaien Zheng Wen Ling Jacob Joseph Dayuan Li Jawahar L Mehta Usha Ponnappan Pei Lin Louis M Fink Martin Hauer-Jensen | 2003 | Blood Coagulation & Fibrinolysis2003，，6： | 1 |
| 13 | Paclitaxel-liposome–microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers显示文摘 | Fei Yan Lu Li Zhiting Deng Qiaofeng Jin Juanjuan Chen Wei Yang Chih-Kuang Yeh Junru Wu Robin Shandas Xin Liu Hairong Zheng | 2013 | Journal of Controlled Release2013，，3： | 1 |
| 14 | Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device显示文摘 | Long Meng Feiyan Cai Qiaofeng Jin Lili Niu Chunxiang Jiang Zhanhui Wang Junru Wu Hairong Zheng | 2011 | Sensors & Actuators: B Chemical2011，，1： | 1 |
| 15 | Paclitaxel-liposome–microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers显示文摘 | Fei Yan Lu Li Zhiting Deng Qiaofeng Jin Juanjuan Chen Wei Yang Chih-Kuang Yeh Junru Wu Robin Shandas Xin Liu Hairong Zheng | 2013 | Journal of Controlled Release2013，，3： | 1 |
| 16 | Deficiency of Microvascular Thrombomodulin and Up-Regulation of Protease-Activated Receptor-1 in Irradiated Rat Intestine显示文摘 | Junru Wang Huaien Zheng Xuemei Ou Louis M. Fink Martin Hauer-Jensen | 2002 | The American Journal of Pathology2002，，： | 1 |
| 17 | Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device显示文摘 | Long Meng Feiyan Cai Qiaofeng Jin Lili Niu Chunxiang Jiang Zhanhui Wang Junru Wu Hairong Zheng | 2011 | Sensors & Actuators: B Chemical2011，，1： | 1 |
| 18 | Recent Advances in Non-Precious Metal-Nitrogen-Carbon Single-Site Catalysts for CO_(2)Electroreduction Reaction to CO显示文摘The carbon dioxide electroreduction reaction(CO_(2)RR)to fuels and/or chemicals is an efficient prospective strategy to realize global carbon management using intermittent electric energy harvested from renewable sources.Highly efficient inexpensive electrocatalysts are required to achieve high energy and Faradaic efficiencies as well as fast conversion.Metal-nitrogen-carbon(M-N-C)single-site catalysts(SSCs)are highly competitive over precious metal catalysts in the CO_(2)RR to CO due to their high performance,easy regulation and low cost.In the past six years,intensive studies of M-N-C SSCs for CO_(2)RR to CO have been performed,and great progress has been achieved.This review focuses on the important topic of CO_(2)RR to CO with M-N-C SSCs.We first introduce the reaction mechanism of the CO_(2)RR to CO and the regulation of the electronic structure from a theoretical viewpoint.Then,the construction of M-N-C SSCs and the regulation of the electronic structure are demonstrated experimentally.The up-to-date electrocatalytic performance of M-N-C SSCs with different metal centers(Ni,Fe,Co and others)is summarized and compared systematically to highlight structure-performance correlations that were considered from both theoretical and experimental perspectives.Finally,the opportunities,challenges and future outlooks are summarized to deepen and widen research and applications in this promising field. | Yiqun Chen Junru Zhang Lijun Yang Xizhang Wang Qiang Wu Zheng Hu | 2022 | Electrochemical Energy Reviews2022，5，4： | 0 |
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