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| 1 | Discussion on the relationship between the Yanshanian Movement and cratonic destruction in North China显示文摘The relationship between the Yanshanian Movement, destruction of the North China Craton(NCC), and subduction of the western Pacific plate is crucial to reconstructing the middle-late Mesozoic tectonic evolution of the eastern Asian continent and margin. The Yanshanian Movement was a globally important change in crustal tectonics during the Middle-Late Jurassic.Previous research has systematically studied the formation and evolution of the Yanshanian Movement, focusing on the timing and location of tectonic movements, and the sedimentary and volcanic strata. However, the question of whether the tectonic activity occurred globally, and the characteristics of the Yanshanian Movement remain debated. The main argument is that if a tectonic movement can only be characterized by a regional or local disconformity, and if the tectonic movement occurred in an intracontinental setting, with extensive deformation but with no disconformity despite volcanic eruptions and magmatic intrusions, accompanied by changes in crustal structure and composition, should it be defined as a tectonic event or process? This question requires further analysis. The main aim of this study is to distinguish whether the Yanshanian Movement is a local feature of the eastern Asian continent, or a global tectonic event related to subduction of the Pacific Plate. In this paper, based on previous research, we discuss the spatial and temporal evolution of the Yanshanian Movement, the controlling tectonic mechanisms, and its relationship to the reactivation and destruction of the NCC and the subduction of the western Paleo-Pacific slab.We emphasize that the Yanshanian Movement in the Middle-Late Jurassic is distinct from the lithospheric thinning responsible for Early Cretaceous extension and magmatism related to the destruction of the NCC. The various tectonic stages were constrained by different dynamics and tectonic settings, or by different tectonic events and processes. Therefore, it is possible that the deformation and reactivation of the NCC contributed to its destruction, in addition to lithospheric thinning. Finally, we discuss whether the Yanshanian Movement was associated with the destruction of the NCC. | Yu WANG Lixin SUN Liyun ZHOU Yueting XIE | 2018 | Science China Earth Sciences2018，61，5： | 13 |
| 2 | Small molecule compound induces chromatin de-condensation and facilitates induced pluripotent stern cell generation显示文摘 | Xiaoyuan Wei Yueting Chen Yongyu Xu YangZhan Ru Zhang Min Wang Qiuhong Hua Haifeng Gu Fajun Nan Xin Xie | 2014 | Journal of Molecular Cell Biology2014，8，5： | 13 |
| 3 | Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway显示文摘Glioblastoma 是最好攻击的大脑肿瘤,并且它的预后仍然保持差。因此,新奇治疗学的策略为 glioma 治疗被需要。Polyphyllin 我(PPI ) ,从巴黎 polyphylla 提取的 bioactive 成分,被报导有反肿瘤活动。然而,为这项活动的详细机制仍然保持不清楚。这里,我们在 vitro 在 glioma 房间和它的机制上调查了 PPI 的禁止的效果。U251 房间为 24 ~ 72 h 与 PPI (2-9 M ) 的各种各样的集中被对待。由 PPI 的 U251 房间增长的抑制被 MTT 试金估计。房间周期和 apoptosis 上的效果被流动 cytometry 与 PI 和 annexin V-FITC/PI 检验双染色,并且房间 mitochondrial 膜潜力水平被荧光显微镜学评估, JC-1 染色。apoptosis 相关的蛋白质和 JNK 信号小径蛋白质的表达式层次被西方的污点分析评估。结果证明 PPI 显著地以一种集中依赖者方式禁止了 U251 房间的增长。PPI 导致了 G 2/M 阶段拘捕和 apoptosis,并且它 upregulated Bax,细胞色素 c,和 p-JNK 的表情,而是 downregulated 在 U251 房间的 anti-apoptotic 蛋白质 Bcl-2 的表示。而且, PPI 挑起了 mitochondrial 膜潜力的去极。另外, PPI 导致的 apoptosis 被 JNK 禁止者 SP600125 显著地压制。我们的数据提供 PPI 禁止增长并且在 U251 房间导致 apoptotic 房间死亡的证据。这效果可以与 JNK 小径被联系。这些结果建议 PPI 是与潜在的 anti-glioma 效果表明小径的 JNK 的使活跃之物。 | Jiaxin Liu Yueting Zhang Li Chen Fei Yu Xiaojin Li Dan Tao Jianhua Zhao Shuai Zhou | 2017 | Acta Biochimica et Biophysica Sinica2017，49，6： | 11 |
| 4 | Promoting remyelination for the treatment of multiple sclerosis:opportunities and challenges显示文摘Multiple sclerosis (MS) is a chronic and devastating autoimmune demyelinating disease of the central nervous system. With the increased understanding of the pathophysiology of this disease in the past two decades, many disease-modifying therapies that primarily target adaptive immunity have been shown to prevent exacerbations and new lesions in patients with relapsing-remitting MS. However, these therapies only have limited efficacy on the progression of disability. Increasing evidence has pointed to innate immunity, axonal damage and neuronal loss as important contributors to disease progression. Remyelination of denuded axons is considered an effective way to protect neurons from damage and to restore neuronal function. The identification of several key molecules and pathways controlling the differentiation of oligodendrocyte progenitor cells and myelination has yielded clues for the development of drug candidates that directly target remyelination and neuroprotection. The long-term efficacy of this strategy remains to be evaluated in clinical trials. Here, we provide an overview of current and emerging therapeutic concepts, with a focus on the opportunities and challenges for the remyelination approach to the treatment of MS. | Yueting Zhang Taylor B.Guo Hongtao Lu | 2013 | Neuroscience Bulletin2013，29，2： | 6 |
| 5 | Analysis of Review Helpfulness Based on Consumer Perspective显示文摘When consumers make purchase decisions, they generally refer to the reviews generated by other consumers who have already purchased similar products in order to get more information. Online transaction platforms provide a highly convenient channel for consumers to generate and retrieve product reviews. In addition,consumers can also vote reviews perceived to be helpful in making their decision. However, due to diverse characteristics, consumers can have different preferences on products and reviews. Their voting behavior can be influenced by reviews and existing review votes. To explore the influence mechanism of the reviewer, the review,and the existing votes on review helpfulness, we propose three hypotheses based on the consumer perspective and perform statistical tests to verify these hypotheses with real review data from Amazon. Our empirical study indicates that review helpfulness has significant correlation and trend with reviewers, review valance, and review votes. In this paper, we also discuss the implications of our findings on consumer preference and review helpfulness. | Yuanlin Chen Yueting Chai Yi Liu Yang Xu | 2015 | Tsinghua Science and Technology2015，20，3： | 6 |
| 6 | Benign prostatic hyperplasia and male lower urinary symptoms:A guide for family physicians显示文摘Male patients with lower urinary tract symptoms(LUTS)and benign prostatic hyperplasia(BPH)are increasingly seen by family physicians worldwide due to ageing demographics.A systematic way to stratify patients who can be managed in the community and those who need to be referred to the urologist is thus very useful.Good history taking,physical examination,targeted blood or urine tests,and knowing the red flags for referral are the mainstay of stratifying these patients.Case selection is always key in clinical practice and in the setting of the family physician.The best patient to manage is one above 40 years of age,symptomatic with nocturia,slower stream and sensation of incomplete voiding,has a normal prostatespecific antigen level,no palpable bladder,and no haematuria or pyuria on the labstix.The roles of α blockers,5-α reductase inhibitors,and antibiotics in a primary care setting to manage this condition are also discussed. | Farhad Fakhrudin Vasanwala Michael Yuet Chen Wong Henry Sun Sien Ho Keong Tatt Foo | 2017 | Asian Journal of Urology2017，4，3： | 5 |
| 7 | Heat Conduction in Multilayered Thermoelectric Materials with Multiple Cracks显示文摘 | Shenghu Ding Yueting Zhou | 2018 | Acta Mechanica Solida Sinica2018，31，4： | 5 |
| 8 | Germination inhibitors detected in Sapium sebiferum seeds显示文摘This study identifies endogenous inhibitors of germination associated with seed dormancy in Sapium sebiferum,Chinese tallow.Seed extracts were separated into five distinct fractions(petroleum ether,ether,ethyl acetate,methanol,and aqueous)and tested for their effect on germination of cabbage seeds.There were no significant differences in germination percentages and germination index(GI)between the solvents and the control.The five fractions differentially reduced germination percentage and GI values of cabbage seeds.According to the GI results,the greatest inhibition was with the ether fraction followed by methanol,ethyl acetate,petroleum ether,and aqueous fractions.Gas chromatography–mass spectrometry identified the constituents of the four organic fractions.Compared with the mass spectrum of the National Institute of Standards and Technology library,a compound was confirmed,provided it was more than 85%similar.Analysis of ether extracts identified four compounds:butylated hydroxytoluene(BHT;19.7%),1,2-benzenediol(4.1%),phydroxycinnamic acid,ethyl ester(2.8%),and n-hexadecanoic acid(1.4%).Fourteen,20,and 9 compounds were identified in methanol,ethyl acetate,and petroleum ether extracts,respectively.The IC50 of BHT(the concentration at which BHT inhibits radicle growth by 50%)was 54.8 mg/L,indicating that the presence of BHT might be the primary cause of dormancy in S.sebiferum seeds. | Tingting Zhao Cunmeng Qian Yunpeng Gao Li Chen Mingwei Zhu Yueting Pan Shuxian Li | 2019 | Journal of Forestry Research2019，30，6： | 4 |
| 9 | Efficacy of Lidan Tang on high-fat-diet induced gallstone in mice and possible mechanism显示文摘OBJECTIVE:To investigate efficacy of Lidan Tang(LDT)on gallstone induced by high fat diet in mice,and to study its underlying mechanism.METHODS:Mice were fed with high fat diet every day and treated with LDT(9.01 times of human clinic dosage).Mice were randomly divided into 6 groups as control group,gallstone model group(high-fat diet),positive control ursodeoxycholic acid(UDCA)group(80 mg·kg^-1·d^-1,i.g.),LDT low dose group(6 kg/d,i.g.),LDT middle dose group(12 kg/d,i.g.),and LDT high dose group(24 kg/d,i.g.).The whole experiment was lasted for 4 weeks.The levels of ALT,AST,LDH,CHO,HDL-C and LDL-C in serum were measured,the pathological sections were observed by hematoxylin-eosin staining,the activities of antioxidant enzymes were measured by kits,and the proteins related to oxidative stress and lipid transport were detected by Western blot analysis.RESULTS:LDT could significantly reduce the contents of ALT and AST in serum and improve the pathological tissue of liver.LDT could significantly reduce the content of MDA and LPO,and increase the level of GSH and GSH-PX in liver tissue.The data of Western blot showed that LDT had antioxidant effect promoting Keap1/Nrf2 pathway and regulated the process of lipid transport,which was statistically significant.In addition,LDT treatment inhibited the expression of ATP-binding cassette transports ABCG5/8 in liver,and reduced cholesterol transport from the hepatocytes to the gallbladder.CONCLUSION:LDT has protective effect on gallstones induced by high fat diet in mice,which might be based on the protective effect on liver,including enhancing the antioxidant capacity of liver and reducing the production of lipid peroxides. | Gao Yan Liu Caipin Li Juntong Zhai Yingying Lin Meiyu Wu Qinglin Chu Shifeng Zhang Zhao Li Jianping Zhou Xin Li Yueting Chen Naihong | 2020 | Journal of Traditional Chinese Medicine2020，40，4： | 4 |
| 10 | Genomic profiling and the impact of MUC19 mutation in hepatoid adenocarcinoma of the stomach显示文摘Dear Editor,Hepatoid adenocarcinoma(HAC)is a rare pathological subtype of extrahepatic tumor,featured by hepatoid differentiation andα-fetoprotein(AFP)-production[1,2].Hepatoid adenocarcinoma of the stomach(HAS),accounting for 0.3%to 1.0%of all gastric cancers(GCs),has attracted increasing attention due to its high degree of malignancy[3].Compared with classic GC,HAS showed a higher rate of vascular invasion,lymph node metastasis,and liver metastasis,with only 9.0%survival rate at 5 years[4].Currently,there is no effective treatment for HAS,and little is known about its pathogenesis.Herein,we investigated the molecular features of HAS and identified potential therapeutic targets for HAS. | Mengxuan Zhu Erbao Chen Shan Yu Chen Xu Yiyi Yu Xin Cao Wei Li Pengfei Zhang Yan Wang Baofeng Lian Shuirong Zhang Yueting Qu Lujia Huang Weiwei Shi Yuehong Cui Li Qian Tianshu Liu | 2022 | Cancer Communications2022，42，10： | 3 |
| 11 | Group sparse representation for image categorization and semantic video retrieval显示文摘Multimedia content analysis and management are a promising and challenging theme.In this paper we develop a novel approach to image representation,which we call group sparse representation (GSR),for image classification and video retrieval.The basic idea is to represent a test image as a weighted combination of all the training images.In particular,we introduce two sets of weight coefficients,one for each training image and the other for each class.Moreover,we formulate our concern as a group nonnegative garrote model.The resulting representations are sparse,and they are appropriate for discriminant analysis.Experiments on Caltech101 and PASCAL VOC2008 image dataset and TRECVID2005 video corpus testify that our proposed approach is efficient and effective. | LIU YaNan WU Fei ZHUANG YueTing | 2011 | Science China(Information Sciences)2011，54，10： | 3 |
| 12 | A Novel Attribute-Based Encryption Approach with Integrity Verification for CAD Assembly Models显示文摘Cloud manufacturing is one of the three key technologies that enable intelligent manufacturing.This paper presents a novel attribute-based encryption(ABE)approach for computer-aided design(CAD)assembly models to effectively support hierarchical access control,integrity verification,and deformation protection for co-design scenarios in cloud manufacturing.An assembly hierarchy access tree(AHAT)is designed as the hierarchical access structure.Attribute-related ciphertext elements,which are contained in an assembly ciphertext(ACT)file,are adapted for content keys decryption instead of CAD component files.We modify the original Merkle tree(MT)and reconstruct an assembly MT.The proposed ABE framework has the ability to combine the deformation protection method with a content privacy of CAD models.The proposed encryption scheme is demonstrated to be secure under the standard assumption.Experimental simulation on typical CAD assembly models demonstrates that the proposed approach is feasible in applications. | Yueting Yang Fazhi He Soonhung Han Yaqian Liang Yuan Cheng | 2021 | Engineering2021，7，6： | 3 |
| 13 | Multiple knowledge representation for big data artificial intelligence:framework,applications,and case studies显示文摘In this paper,we present a multiple knowledge representation(MKR)framework and discuss its potential for developing big data artificial intelligence(AI)techniques with possible broader impacts across different AI areas.Typically,canonical knowledge representations and modern representations each emphasize a particular aspect of trans-forming inputs into symbolic encoding or vectors.For example,knowledge graphs focus on depicting semantic connections among concepts,whereas deep neural networks(DNNs)are more of a tool to perceive raw signal inputs. | Yi YANG Yueting ZHUANG Yunhe PAN | 2021 | Frontiers of Information Technology & Electronic Engineering2021，22，12： | 3 |
| 14 | The Next Breakthroughs of Artificial Intelligence:The Interdisciplinary Nature of AI显示文摘1.Introduction Artificial intelligence(AI)is committed to the realization of machine-borne intelligence.The technologies underpinning AI have made huge leaps in the past decade,bringing exciting applications such as language understanding,vision recognition,and intelligent digital assistants.However,contemporary AI systems are good at specific predefined tasks and are unable to learn by themselves from data or from experience,intuitive reasoning,and adaptation. | Yueting Zhuang Ming Cai Xuelong Li Xiangang Luo Qiang Yang Fei Wu | 2020 | Engineering2020，6，3： | 3 |
| 15 | Evolution of Specialization with Reachable Transaction Scope Based on a Simple and Symmetric Firm Resource Allocation Model显示文摘In the last decade, as an emerging transaction measure driven by computer and internet technology,e-commerce experienced explosive growth in many areas. It has greatly broken down the limitations of space and time to economic activities, thus changing the rules of business fundamentally. Significant work has been done to understand the laws of e-commerce from multiple dimensions, but the question of how e-commerce shapes firms' specialization and market structure from the perspective of spatial factors remains obscure. In this paper, we propose a simple and symmetric firm resource allocation model with a specialized-economy production function and market size constraint, to investigate how individual firms adjust resource allocation with reachable transaction scope expanded. It is shown that with the expansion of reachable transaction scope, individual firms discretely take back one unit resource from a low-investment direction and, instead, channel it to a 'specialized direction'.Meanwhile, at the macro level, an optimal division network evolves from a static self-sufficient stage to a diverse semi-specialized stage, and finally to a highly integrated completely specialized stage. Ergo, a Complex Adaptive System(CAS) based simulation framework is constructed. Designed simulation experiments are carried out and confirm to the analysis result of our proposed model. | Xiao Sun Yueting Chai Yi Liu Jianping Shen Yadong Huang | 2017 | Tsinghua Science and Technology2017，22，1： | 2 |
| 16 | High Incidence of Mortality and Recurrent Bleeding in Patients With Helicobacter pylori –Negative Idiopathic Bleeding Ulcers显示文摘 | Grace Lai–Hung Wong Vincent Wai–Sun Wong Yawen Chan Jessica Yuet–Ling Ching Kim Au Aric Josun Hui Larry Hin Lai Dorothy Kai–Lai Chow Danny Ka–Fai Siu Yan–Ni Lui Justin Che–Yuen Wu Ka–Fai To Lawrence Cheung–Tsui Hung Henry Lik–Yuen Chan Joseph Jao–Yiu Sung | 2009 | Gastroenterology2009，，2： | 2 |
| 17 | Cytotoxicity and genotoxicity assessment of Euphorbia hirta in MCF-7cell line model using comet assay显示文摘Objective:To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta(E.hirta)in MCF-7 cell line model using comet assay.Methods:The cytotoxicity of E.hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E.hirta was assessed by using Comet assay.Results:Both toxicity tests exhibited significant toxicity result.In the comet assay,the E.hirta extract exhibited genotoxicity effects against MCF-7 DNA in a time-dependent manner by increasing mean percentage of DNA damage.The extract of E.hirta showed significant toxicity against brine shrimp with an LC_(50)value of 620.382μg/mL(24 h).Comparison with positive control potassium dichroniate signifies that cytotoxicity exhibited by the methanol extract might have moderate activity.Conclusion:The present work confirmed the cytotoxicity and genotoxicity of E.hirta.However,the observed toxicity of E.hta extracts needs to be confirmed in additional studies. | Kwan Yuet Ping Ibrahim Darah Yeng Chen Sreenivasan Sasidharan | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 2 |
| 18 | Improved Region Merging Algorithm for Remote Sensing Images显示文摘To segment high-resolution remote sensing images(RSIs)accurately on an object level and meet the precise boundary dividing requirement,an improved superpixel segmentation and region merging algorithm is proposed.Simple linear iterative clustering(SLIC)is widely used because of its advantages in performance and effect;however,it causes over-segmentation,which is very disadvantageous to information extraction.In this proposed method,SLIC is firstly adopted for initial superpixel partition.The second stage follows the iterative merging procedure,which uses a hierarchical clustering algorithm and introduces a local binary pattern(LBP)texture feature operator during the process of merging.The experimental results indicate that the proposed method achieved a good segmentation and region merging performance,and worked effectively on cloud detection preprocessing in high-resolution RSIs with cloud and snow overlap situations. | Zhuo Wu Xiaohua Wang Yongwen Shen Yueting Shi | 2020 | Journal of Beijing Institute of Technology2020，29，1： | 2 |
| 19 | Development of a Questionnaire to Measure the Level of Reflective Thinking显示文摘 | David Kember Doris Y. P. Leung Alice Jones Alice Yuen Loke Jan McKay Kit Sinclair Harrison Tse Celia Webb Frances Kam Yuet Wong Marian Wong Ella Yeung | 2000 | Assessment & Evaluation in Higher Education2000，，4： | 2 |
| 20 | Efficacy and tolerability of vardenafil in Asian men with erectile dysfunction显示文摘瞄准:评估功效和 vardenafil 的 toler 能力,一个 phosphodiesterase type-5 (PDE-5 ) 禁止者,在有可勃起的机能障碍(编辑) 的亚洲种族的人。方法:在这未来,双窗帘,多民族的学习,亚洲人被使随机化收到 vardenafil (10 mg ) 或安慰剂(4:1 比率) 12 个星期。主要功效变量是可勃起的功能的国际索引可勃起的功能领域(IIEF-EF ) ,和性相遇侧面(9 月) 与穿入和交际结束有关询问。重要吝啬的改进在所有三项措施被要求显示出 vardenafil 处理的积极好处。第二等的功效变量在勃起改进上包括了全球评价问题(GAQ ) 。结果:最少平方的吝啬的基线 IIEF-EF 领域分数(vardenafil 14.6,安慰剂 13.4 ) 与在 12 个星期以后的中等编辑一致, vardenafil 处理与安慰剂相比在 IIEF-EF 领域分数从基线与重要增加被联系(22.4 对 14.3;P <
0.001 ) 。Vardenafil 在吝啬的成功为 SEP-2 评估的最少的广场(LS ) 从基线与重要改进被联系(vardenafil 82.2 对安慰剂 43.6;P <
0.001 ) 并且 SEP-3 (vardenafil 66.1 对安慰剂 24.0;P <
0.001 ) 。积极 GAQ 回答被 81.8% vardenafil 接受者对 24.3% 安慰剂接受者报导。不利事件被 25.4% vardenafil 组,报导温和、短暂的多数。结论:Vardenafil (10 mg ) 是为在亚洲男人的中等编辑的一个高度有效、容忍得好的处理。这些结果增加在耐心的人口的一个范围为编辑的治疗表明 vardenafil 的安全和功效的数据的增加的数量。 | Hui Meng Tan Chong Min Chin Chong Beng Chua Edsal Gatchalian Apichat Kongkanand Clarence Lei Chang Moh Foo Cheong Ng Krisada Ratana-Olarn Dennis Serrano Akmal Taher Ismail Tambi Anupan Tantiwong Michael Wong Yuet Chen Wai-Chun Yip | 2008 | Asian Journal of Andrology2008，10，3： | 2 |
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