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| 1 | Targeted Mutagenesis of NAC Transcription Factor Gene,OsN AC041,Leading to Salt Sensitivity in Rice显示文摘Salinity is a major abiotic stress factor that seriously affects plant growth. Many genes are involved in the response to salt stress with various metabolism pathways. A number of plant transcription factor family genes have been found to be involved in the salt stress response, and NAM, ATAF and CUC(NAC) transcription factors are thought to act as active regulators during abiotic stress, especially salt stress. In this study, we detected a rice NAC transcription factor coding gene, OsNAC041, and confirmed that it influenced the germination of seeds under salt stress and salt tolerance of plants. OsNAC041 was primarily expressed in the leaves and located in the nucleus. Furthermore, the CRISPR/Cas9 method was used to obtain a targeted osnac041 mutant, of which the plant height was higher than that of the wild-type, showing increased salt sensitivity. Moreover, RNA-seq analysis revealed a number of differentially expressed genes(DEGs) involved in several important signaling pathways in the osnac041 mutant. Subsequently, Kyoto Encyclopedia of Genes and Genomes annotation also revealed differential expression of DEGs associated with mitogen-activated protein kinase signaling, peroxisome, eukaryotictype ABC transporters, photosynthesis and plant hormones, which are involved in stress-related signaling pathways. Overall, our study suggested that OsNAC041 was involved in the salt stress response in rice. These findings not only provide empirical evidence of OsNAC041 function, but also provide new insight into its potential application in rice resistance breeding. | WANG Bo ZHONG Zhaohui ZHANG Huanhuan WANG Xia LIU Binglin YANG Lijia HAN Xiangyan YU Deshui ZHENG Xuelian WANG Chunguo SONG Wenqin CHEN Chengbin ZHANG Yong | 2019 | Rice science2019，26，2： | 8 |
| 2 | Room temperature preparation of highly stable cesium lead halide perovskite nanocrystals by ligand modification for white lightemitting diodes显示文摘The poor stability of halide perovskite nanocrystals(NCs)has severely hindered future practical application.Herein,we proposed a facile and effective ligand modification route to synthesize stable CsPbBr_(3) nanocrystals by introducing a double-terminal ligand,namely 4,4'-Azobis(4-cyanovalericacid)(CA),to replace the conventional oleic acid(OA)ligand at room temperature.The as-synthesized CsPbBr_(3)-CA not only possesses high photoluminescence quantum yield(72%)related to the reduced trap defects,but also shows significantly improved stability exposure to water,ethanol,light,and/or heat benefiting from the CA ligand anchored to NC surfaces tightly.The photoluminescence intensity of CsPbBr_(3)-CA maintains about 80%and 75%of its initial emission intensity after immersed in water or ethanol for 360 min,respectively,whereas that of the CsPbBr_(3)-OA was quenched completely within a few minutes.Moreover,an all-inorganic white light-emitting diode(LED)covered 126%National Television System Committee(NTSC)standard and 92%Rec.2020 standard was fabricated by combining the green CsPbBr_(3)-CA and commercial red-emitting K2SiF6:Mn4+(KSF)phosphors onto a blue LED chip.Thus,the presented work initiates the development of the room temperature preparation of high quality CsPbBr_(3) and shows prospect for next-generation displays. | Yu Zhang Guishun Li Changkun She Shaohua Liu Fangyu Yue Chengbin Jing Ya Cheng Junhao Chu | 2021 | Nano Research2021，14，8： | 3 |
| 3 | Bubble breakup in a microfluidic T-junction显示文摘我们进行计算液体动力学模拟用 volume-of-fluid 方法在 microfluidic T 连接调查水泡决裂的行为代表接口。水泡形态学的进化和流动地里的速度和压力的分布被分析,并且在水泡形态学上的主要隧道和分支之间的宽度比率的效果被评估。结果显示那,隧道决裂,妨碍的决裂,联合决裂和非决裂在不同状况下面通过 T 连接在水泡流动期间被观察。整个水泡决裂进程经历扩展,压榨并且拧离开阶段,当非决裂进程经历扩展,推上演时。当在水泡内的速度具有为妨碍的决裂的寓言的分布时,我们发现在 squeeze 阶段,本地旋涡流动为隧道决裂在水泡的前面边形成。不管非决裂政体,有突然的压力落下,在 squeeze 发生在水泡的煤气液体的接口舞台,和在前面接口的压力落下在消沉区域比那远大。通过 T 连接的水泡决裂政体的转变随主要隧道的宽度比率的增加发生到分支,它顺序经历非决裂政体,隧道决裂政体和妨碍的决裂政体。流动政体图与幂定律关联被阴谋区分水泡 / 微滴决裂和非决裂政体,它也通过 T 连接描绘水泡和微滴决裂之间的差别。 | Xiangdong Liu Chengbin Zhang Wei Yu Zilong Deng Yongping Chen | 2016 | Science Bulletin2016，61，10： | 1 |
| 4 | Thermal properties and Hammability of polylactide nanocomposites with aluminum trihydrate and organoclay显示文摘 | Cheng Kuochung Yu Chengbin Guo Wenjeng | 2012 | Carbohydrate Poly- mers2012，87，2： | 1 |
| 5 | Design, testing and analysis of a novel composite magnetorheological fluid clutch 显示文摘 | Dai Shangqiu Du Chengbin Yu Guojun | 2013 | Journal of Intelligent Material Systems and Structures2013，24，14： | 1 |
| 6 | Let7a inhibits the growth of endometrial carcinoma cells by targeting Aurora-B显示文摘 | Ping Liu Meiyan Qi Chengbin Ma Guoying Lao Yu Liu Yan Liu Yingzi Liu | 2013 | FEBS Letters2013，，： | 1 |
| 7 | Reliability optimization of a redundant system with failure dependencies 显示文摘 | Yu Haiyang Chu Chengbin Chatelet E | 2007 | Reliability Engineering System Safety2007，92，12： | 1 |
| 8 | A Magnetic Flux Leakage Study of a Self-decoupling Magnetorheological Damper 显示文摘 | DU Chengbin WAN Faxue YU Guojun | 2011 | Smart Materials and Structures2011，20，6： | 1 |
| 9 | The fabrication of a photoresponsive molecularly imprinted polymer for the photoregulated uptake and release of caffeine 显示文摘 | Gong Chengbin Michael Lam Hon Wah Yu Hongxia | 2006 | Advanced Functional Materials2006，16，13： | 1 |
| 10 | A Novel Symbol Overlapping FFH-OCDMA system 显示文摘 | SHENG CHENGBIN WU CHEN YU J1NHUI | 2004 | Chinse Optics Letters2004，2，2： | 1 |
| 11 | Reliability optimization of a redundant system with failure depend- encies显示文摘 | Yu Haiyang Chu Chengbin Chatelet E | 2007 | Reliability Engineering and System Safety2007，92，12： | 1 |
| 12 | Reliability optimization of a redundant system with failure dependencies显示文摘 | YU Haiyang CHU Chengbin CHATELET E | 2007 | Reliability Engineering and System Safety2007，92，12： | 1 |
| 13 | Design,Testing and Analysis of a Novel Composite Mag-netorheological Fluid Clutch显示文摘 | Dai Shangqiu Du Chengbin Yu Guojun | 2013 | Journal of Intelli-gent Material Systems and Structures2013，24，14： | 1 |
| 14 | Design,testing and analysis of a novel composite magnetorheological fluid clutch显示文摘 | DAI Shangqiu DU Chengbin YU Guojun | 2013 | Journal of Intelligent Material Systems and Structures2013，24，14： | 1 |
| 15 | Thermal properties and flammability of polylactide nano- composites with aluminum trihydrate and organoelay显示文摘 | Cheng Kuochung Yu Chengbin Guo Wenjeng | 2012 | Carbohydrate Polymers2012，87，： | 1 |
| 16 | Developmental Temporal Patterns and Molecular Network Features in the Transcriptome of Rat Spinal Cord显示文摘The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understood in placental mammals,especially in terms of their relationships with vital biological processes such as regeneration.Here,using a large-scale temporal transcriptomic analysis of rat spinal cord from the embryonic stage to adulthood,we show that fluctuating RNA expression levels reflect highly active transcriptional regulation,which may initiate spinal cord patterning.We also demonstrate that microRNAs(miRNAs)and transcriptional factors exhibit a mosaic profile based on their expression patterns,while differential alternative splicing events reveal that alternative splicing may be a driving force for the development of the node of Ranvier.Our study also supports the existence of a negative correlation between innate immunity and intrinsic growth capacity.Epigenetic modifications appear to perform their respective regulatory functions at different stages of development,while guanine nucleotidebinding protein(G protein)-coupled receptors(including olfactory receptors(ORs))may perform pleiotropic roles in axonal growth.This study provides a valuable resource for investigating spinal cord development and complements the increasing number of single-cell datasets.These findings also provide a genetic basis for the development of novel tissue engineering strategies. | Jian Yang Lili Zhao Sheng Yi Fei Ding Yumin Yang Yan Liu Yongjun Wang Mei Liu Chengbin Xue Lian Xu Leilei Gong Xinghui Wang Yu Zhang Bin Yu Guo-li Ming Xiaosong Gu | 2021 | Engineering2021，7，11： | 0 |
| 17 | The SARS-CoV-2 spike L452R-E484Q variant in the Indian B.1.617 strain showed significant reduction in the neutralization activity of immune sera显示文摘To assess the impact of the key non-synonymous amino acid substitutions in the RBD of the spike protein of SARS-CoV-2 variant B.1.617.1(dominant variant identified in the current India outbreak)on the infectivity and neutralization activities of the immune sera,L452R and E484Q(L452R-E484Q variant),pseudotyped virus was constructed(with the D614G background).The impact on binding with the neutralizing antibodies was also assessed with an ELISA assay.Pseudotyped virus carrying a L452R-E484Q variant showed a comparable infectivity compared with D614G.However,there was a significant reduction in the neutralization activity of the immune sera from non-human primates vaccinated with a recombinant receptor binding domain(RBD)protein,convalescent patients,and healthy vaccinees vaccinated with anmRNA vaccine.In addition,there was a reduction in binding of L452R-E484Q-D614G protein to the antibodies of theimmune sera fromvaccinated nonhuman primates.These results highlight the interplay between infectivity and other biologic factors involved in the natural evolution of SARS-CoV-2.Reduced neutralization activities against the L452R-E484Q variant will have an impact on health authority planning and implications for the vaccination strategy/newvaccine development. | Gen Li Zhongcheng Zhou Peng Du Meixing Yu Ning Li Xinxin Xiong Hong Huang Zhihai Liu Qinjin Dai Jie Zhu Chengbin Guo ShanyunWu Daniel T.Baptista-Hon Man Miao LamWai Ming Yong Wu Fanxin Zeng Charlotte L.Zhang Edward D.Zhang Haifeng Song Jianghai Liu Johnson Yiu-Nam Lau Andy P.Xiang Kang Zhang | 2021 | Precision Clinical Medicine2021，4，3： | 0 |
| 18 | Two-dimensional mesoporous sensing materials显示文摘Two-dimensional mesoporous materials combing ultrathin nanosheet morphology with well-defined mesoporous structures,are now emerging and becoming increasingly important for their promising applications in energy storage,electronic devices,electrocatalysts and so on.Here,we synthesized a kind of polypyrrole-based two-dimensional mesoporous materials with uniform pore size,ultrathin thickness and high surface area.Serving for electrochemical NH3 sensor,they exhibited a fast response and high sensitivity.Therefore,our study would promote much interest in design of new materials for gas sensor applications. | Yu Wen Facai Wei Wenqian Zhang Anyang Cui Jing Cui Chengbin Jing Zhigao Hu Qingguo He Jianwei Fu Shaohua Liu Jiangong Cheng | 2020 | Chinese Chemical Letters2020，31，2： | 0 |
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