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| 1 | The zircon SHRIMP chronology and trace elementgeochemistry of the Carboniferous volcanic rocksin western Tianshan Mountains显示文摘The genesis of the Carboniferous volcanic rocks in the Dahalajunshan group, mainly consisting of trachytes and trachy-andesites and distributing widely in western Tianshan Mountains, remains to be controversial. It has been proposed to be relevant to “rift” or “plume”. Detailed pe-trology and geochemical data presented in this paper show that these volcanic rocks represent typical continental arc magmatism. The volcanic rocks are mainly trachy-andesitic, and the magma source is enriched in LILE, Th and Pb, and depleted in HFSE and Ce. Trace element geochemical study suggests that the basalts could be modeled by 7%-11% partial melt of garnet lherzolite. The volcanic rocks in the Dahala-junshan group are neither the products of “rift” nor so-called “plume” but represent the continental island arc of the Pa-leo-Southern Tianshan Ocean. The mantle wedge had been modified by the melt generating in subduction zone during a long evolution history of this island arc. The continental crust materials (i.e. mainly sediment on ocean floor) had been added into island arc through melt in subduction zone. Volcanic rocks occurring in different regions might represent magma eruption in different time. The zircon SHRIMP dat-ing indicates that the ages of the basalt varies between 334.0 Ma and 394.9 Ma. The 13 analyses give an average age of 353.7 ±4.5 Ma (MSWD = 1.7). The apparent ages of zircons in trachy-andesite vary between 293.0 Ma and 465.4 Ma. All analyses fall on the U-Pb concordant line and are divided into two groups. 8 analyses produce an average age of 312.8±4.2 Ma (MSWD = 1.7), which represents the crystal-lizing age of zircon rims in trachy-andesite. The acquired two ages (i.e. 354 and 313 Ma) belong to the Early Carboniferous and Late Carboniferous epochs, respectively. Thus, the Da-halajunshan group would be separated into several groups with the accumulation of high-quality age dating and data of trace element and isotopic geochemistry, in our opinion. | ZHU Yongfeng ZHANG Lifei GU Libing GUO Xuan ZHOU Jing | 2005 | Chinese Science Bulletin2005，50，19： | 188 |
| 2 | Significance of native arsenic in the Baogutu gold deposit, western Junggar, Xinjiang, NW China显示文摘Native arsenic together with comb quartz and stibnite is found in the Baogutu gold deposit, western Junggar (Xinjiang), NW China. It is anhedral with various grain size (<0.001 to 2 mm), and contains 98 wt% to 98.7 wt% As. Micro-granular electrum, the main auriferous mineral in the Baogutu gold deposit, is commonly enclosed in or closely accompanied by native arsenic. Three ore-forming paragenetic stages could be identified. Native arsenic mainly formed at stage II which is also the major stage for gold deposition. Mineral assemblage formed at this stage is native arsenic-stibnite-electrum-arseno- pyrite-miargyrite-freibergite-pyrrhotite-pyrite. Based on native arsenic and its coexisting minerals, the temperature (230 to 170℃), oxygen fugacity (logfO2 = -42―-56.5) and sulfur fugacity (logf S2 = -13.3― -16.6) of stage II are estimated. From stage I to stage II, the temperature, sulfur fugacity and S2- concentration of hydrothermal fluid decrease obviously, whereas the As concentration increases. Coexistence with native arsenic of electrum and its contents of 0.5 wt%―1.3 wt% As suggest that As is important to transport Au when S2- concentration decrease in hydrothermal fluid. Crystallization of native arsenic induced the deposition of electrum and consequently the formation of the Baogutu gold deposit. | AN Fang & ZHU YongFeng The Key Laboratory of Orogenic Belts and Crustal Evolution, Ministry of Education School of Earth and Space Sciences, Peking University, Beijing 100871, China | 2009 | Chinese Science Bulletin2009，54，10： | 17 |
| 3 | Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol显示文摘Menopause is associated with dyslipidemia and an increased risk of cardio-cerebrovascular disease.The classic view assumes that the underlying mechanism of dyslipidemia is attributed to an insufficiency of estrogen.In addition to a decrease in estrogen, circulating follicle-stimulating hormone (FSH)levels become elevated at menopause.In this study,we find that blocking FSH reduces serum cholesterol via inhibiting hepatic cholesterol biosynthesis.First,epidemiological results show that the serum FSH levels are positively correlated with the serum total cholesterol levels,even after adjustment by considering the effects of serum estrogen,in addition,the prevalence of hypercholesterolemia is significantly higher in peri-menopausal women than that in premenopausal women.Furthermore,we generated a mouse model of FSH elevation by intraperitoneally injecting exogenous FSH into ovariectomized (OVX)mice,in which a normal level of estrogen (E2)was maintained by exogenous supplementation. Consistently,the results indicate that FSH,independent of estrogen,increases the serum cholesterol level in this mouse model. Moreover,blocking FSH signaling by anti-FSHβ antibody or ablating the FSH receptor (FSHR)gene could effectively prevent hypercholesterolemia induced by FSH injection or high-cholesterol diet feeding.Mechanistically,FSH,via binding to hepatic FSHRs, activates the Gi2α/β-arrestin-2/Akt pathway and subsequently inhibits the binding of FoxO1 with the SREBP-2 promoter,thus preventing FoxO1 from repressing SREBP-2 gene transcription.This effect,in turn,results in the upregulation of SREBP-2,which drives HMGCR nascent transcription and de novo cholesterol biosynthesis,leading to the increase of cholesterol accumulation.This study uncovers that blocking FSH signaling might be a new strategy for treating hypercholesterolemia during menopause, particularly for women in peri-menopause characterized by FSH elevation only. | Yanjing Guo Meng Zhao Tao Bo Shizhan Ma Zhongshang Yuan Wenbin Chen Zhao He Xu Hou Jun Liu Zhenhai Zhang Qiang Zhu Qiangxiu Wang Xiaoyan Lin Zhongli Yang Min Cui Lu Liu Yujie Li Chunxiao Yu Xiaoyi Qi Qian Wang Haiqing Zhang Qingbo Guan Lifang Zhao Shimeng Xuan Huili Yan Yanliang Lin Li Wang Qihang Li Yongfeng Song Ling Gao Jiajun Zhao | 2019 | Cell Research2019，29，2： | 16 |
| 4 | Palaeogeomorphology and its control on the development of sequence stratigraphy and depositional systems of the Early Silurian in the Tarim Basin显示文摘The Silurian in the Tarim Basin was deposited on the basement deformed by the Caledonian tectonic movements at the end of the Late Ordovician. The development and distribution of sedimentary sequences of the Early Silurian have been clearly controlled by the palaeogeomorphology of the Late Ordovician. Based on unconformity characteristics and distribution of erosion, several zones can be differentiated including a high uplifted erosion zone, a transitional slope zone and a depression zone. The central and west Tabei Uplift zones show high angular unconformity and intense erosion. The Tarim Basin in the late Ordovician shows characteristics of higher in the west, lower in the east while higher in the south, lower in the north. The Early Silurian mainly developed transgressive and highstand systems tracts on the whole, while the lowstand systems tract only developed partly below the slope break. The palaeogeomorphology controlled the clastic source supply and deposit distribution. Braided delta system and tidal flat–estuary system were deposited. The duration of uplifting of the Tazhong paleouplift was longer than that of the Tabei paleo-uplift, and deposition was later. This led to the lower and middle members of the Kepingtage Formation missing in that area. As a large-scale transgression occurred during the deposition period of the upper member of the Kepingtage Formation, sediment from the west of the basin was transported and deposited by tides and waves, forming tidal–marine debris systems above the uplift. Proximal alluvial fan and fan delta coarse clastic deposits developed in proximal uplift zone in the east and southeast of the basin, and braided delta put forward to the transitional zone between the edge of uplift and the sea. Large-scale tidal channel, sub-distributary channel and mouth bar of the delta front can form favorable reservoirs, and they are primary targets for oil and gas exploration. This research on sequence–depositional systems development and distribution controlled by palaeogeomorphology is significant in guiding the prediction of reservoir sandstones. | Liu Jingyan Lin Changsong Cai Zhenzhong Zhu Yongfeng Yang Yongheng Peng Li Si Baoling Huang Zhen Li Huanpu Xu Yingcai Su Zhenzhen | 2010 | Petroleum Science2010，7，3： | 13 |
| 5 | Accumulation and Reformation of Silurian Reservoir in the Northern Tarim Basin显示文摘Silurian sandstone in Tarim Basin has good reservoir properties and active oil and gas shows,especially thick widely-distributed bituminous sandstone.Currently,the Silurian was found containing both bitumen and conventional reservoirs,with petroleum originating from terrestrial and marine source rocks.The diversity of their distribution was the result of 'three sources,three stages' accumulation and adjustment processes.'Three sources' refers to two sets of marine rocks in Cambrian and Middle-Upper Ordovician,and a set of terrestrial rock formed in Triassic in the Kuqa depression.'Three stages' represents three stages of accumulation,adjustment and reformation occurring in Late Caledonian,Late Hercynian and Late Himalayan,respectively.The study suggests that the Silurian bitumen is remnants of oil generated from Cambrian and Ordovician source rocks and accumulated in the sandstone reservoir during Late Caledonian-Early Hercynian and Late Hercynian stages,and then damaged by the subsequent two stages of tectonic uplift movements in Early Hercynian and Pre-Triassic.The authors presumed that the primary paleo-reservoirs formed during these two stages might be preserved in the Silurian in the southern deep part of the Tabei area.Except for the Yingmaili area where the Triassic terrestrial oil was from the Kuqa Depression during Late Himalayan Stage,all movable oil reservoirs originated from marine sources.They were secondary accumulations from underlying Ordovician after structure reverse during the Yanshan-Himalayan stage.Oil/gas shows mixed-source characteristics,and was mainly from Middle-Upper Ordovician.The complexity and diversity of the Silurian marine primary properties were just defined by these three stages of oil-gas charging and tectonic movements in the Tabei area. | ZHU Guangyou CUI Jie SU Jin YANG Haijun ZHANG Bin HU Jianfeng ZHU Yongfeng | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 13 |
| 6 | Geochemistry of hydrothermal gold deposits:A review显示文摘在热水的改变期间形成的矿物质集合反映形成矿石的液体的 geochemical 作文。黄金主要作为 AuCl 和 AuS 建筑群在答案被搬运。象温度,压力,氧易逃逸,和硫易逃逸那样的物理化学的条件的变化是为金降水的有效机制。黄金趋于在高温度和压力在液体的蒸汽阶段被专注。AuAs 和 AuSb 协会在金沉积物是普通的。本国的锑或砷土著人金牌集合可以与低硫易逃逸从热水的液体猛抛。形成 epithermal 金牌沉积物的热水的液体在大多数情况中是浸透 Au 的,而巫婆类型的液体是 Au-undersaturated。从通过吸收的热水的液体的伪稳定的同样忍受的黄铁矿摘录固体答案 Au。同样忍受的黄铁矿的能力从下面浸透的液体吸收 Au 是大规模巫婆类型沉积物的形成的关键。与增加新数据,金存款的地球化学上的研究能被用来跟踪形成矿石的液体,黄金的来源,和 Au 和另外的形成矿石的元素的搬运形式的起源,例如 Si, S, F, Cl,并且 Ag。 | Yongfeng Zhu Fang An Juanjuan Tan | 2011 | Geoscience Frontiers2011，2，3： | 12 |
| 7 | A two degree of freedom stable quasi-zero stiffness prototype and its applications in aseismic engineering显示文摘In this paper, an archetypal aseismic system is proposed with 2-degree of freedom based on a smooth and discontinuous(SD)oscillator to avoid the failure of electric power system under the complex excitation of seismic waves. This model comprises two vibration isolation units for the orthogonal horizontal directions, and each of them admits the stable quasi-zero stiffness(SQZS)with a pair of inclined linear elastic springs. The equation of motion is formulated by using Lagrange equation, and the SQZS condition is obtained by optimizing the parameters of the system. The analysis shows that the system behaves a remarkable vibration isolation performance with low resonant frequency and a large stroke of SQZS interval. The experimental investigations are carried out to show a high sonsistency with the theoretical results, which demonstrates the improvement of aseismic behavior of the proposed model under the seismic wave. | ZHU GuangNan LIU JiYe CAO QingJie CHENG YongFeng LU ZhiCheng ZHU ZhuBing | 2020 | Science China(Technological Sciences)2020，63，3： | 10 |
| 8 | Paleozoic Intrusive Rocks in the Nalati Mountain Range(NMR), Southwest Tianshan: Geodynamic Evolution Based on Petrology and Geochemical Studies显示文摘A synthesis involving the data for the Nalati mountain region(NMR) in west Tianshan with a dataset including zircon U-Pb ages, Hf isotopic composition, major and trace elements of Paleozoic intrusions are presented to improve the understanding of regional geodynamic evolution. Paleozoic intrusive rocks in the NMR could be classified into four categories based on chronological and geochemical data: 480?5 Ma, 445–410 Ma, 345–320 Ma, and 295 Ma, which correspond to(1) closure of the Terskey Ocean and the opening of the south Tianshan back-arc basin, which was followed with the opening of the south Tianshan Ocean,(2) initial subduction of the south Tianshan oceanic crust,(3) major subduction stage, and(4) collision to post-collisional stage, respectively. Following the closure of the Terskey Ocean, the south Tianshan Ocean opened at Early Silurian and subducted under Yili-central Tianshan by the end of Early Carboniferous Period. The following breakoff of the subducted slab triggered partial melting of continental crust and formed voluminous granitic rocks in the NMR. | Huichao Zhang Yongfeng Zhu Wanyi Feng Yuwen Tan Fang An Jiahao Zheng | 2017 | Journal of Earth Science2017，28，2： | 9 |
| 9 | Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex显示文摘To determine whether repetitive transcranial magnetic stimulation(rTMS)of the visual cortex(VC)provides effective and welltolerated treatment and whether magnetic resonance imaging(MRI)measures functional change of the VC as a biomarker of therapeutic effect in major depressive disorder(MDD),we performed a sham-controlled,double-blind,randomized,three-arm VC rTMS treatment study in 74 MDD patients.Neuronavigated rTMS(10 Hz,90%of resting motor threshold,1,600 pulses over20 min twice per day)was performed over the VC for five days.Clinical outcome was measured by Hamilton Depression Rating Scale(HAMD-24)at days 0,1,3,5 and after terminating rTMS,with follow-up at four weeks.MRI was measured at days 0 and5.The individualized group exhibited the greatest change in HAMD-24 scores after VC rTMS for 5 days(F=5.53,P=0.005),which were maintained during follow-up period(F=4.22,P=0.016).All patients reported good tolerance.Changes in VC taskrelated functional MRI correlated with symptomatic reduction in the individualized group.Treatment reduced the initially abnormal increase in resting state functional connectivity from the VC to the pre/subgenual anterior cingulate cortex at day 5,especially in the individualized group.We demonstrated therapeutic potential and good tolerance of VC rTMS in MDD patients,indicated by biomarkers of f MRI measurement. | Zhijun Zhang Hongxing Zhang Chun-Ming Xie Meng Zhang Yachen Shi Ruize Song Xiang Lu Haisan Zhang Kun Li Bi Wang Yongfeng Yang Xianrui Li Jianli Zhu Yang Zhao Ti-Fei Yuan Georg Northoff | 2021 | Science China(Life Sciences)2021，64，1： | 8 |
| 10 | Geological Evolution and Huge Ore-Forming Belts in the Core Part of the Central Asian Metallogenic Region显示文摘The multi-stage geological evolution and extensive continental deformations during the course of its history make the Central Asian metallogenic region(CAMR) a unique and complicated large-scale metal domain. New geological observations and precise age-data allow an improved reconstruction of the geological evolution of the CAMR. This paper summarizes the Paleozoic orogenic evolution and related ore formation in the core part of the CAMR based on the geological data published both during the Soviet period and the last decades. Four ore-formation provinces(Altay, BalkhashJunggar, Chu-Yili-Tianshan, and Southwest Tianshan) could be classified. The Balkhash-Junggar and Chu-Yili-Tianshan provinces are the major topics of this paper. The Balkhash-Junggar province consists of 4 huge ore-forming belts(Zharma-Saur, Tarbahtay-Xiemistay, Aktogay-Baerluke, Balkhashwestern Junggar) with 11 large ore-college areas. The Chu-Yili-Tianshan province consists of 4 huge ore-forming belts(Alatau-Sairimu, Chu-Yili-Bolehuole, Issyk-Awulale, Kazharman-Nalaty) with 22 large ore-college areas. Formation of large ore-college area corresponds to a specific stage of continental crust growth. Comparison of geology and ore deposits in the CAMR provides rich information for future exploration and understanding of ore-forming processes. The Paleo-Junggar Ocean closed at Early Devonian in the Balkhash-western Junggar ore-forming belt. Afterwards, widespread volcanic- sedimentary rocks formed at extensional stage due to delamination of the thick lower crust formed during previous accretionary processes. Felsic magma intrusion caused formation of porphyry Cu-Au deposit at ~310 Ma and related hydrothermal gold deposits about 10 Ma later. For example, in the Hatu-Baobei-Sartohay Au-Cr ore-college area in the Balkhash-western Junggar ore-forming belt, small granitic to diorite plutons and various dykes(312–277 Ma) and large granite bodies(~300 Ma) intruded into the Devonian to Early Carboniferous volcano-sedimentary basin. These magmatic activities and fault systems mainly controlled ore-forming processes. | Yongfeng Zhu Fang An Wangyi Feng Huichao Zhang | 2016 | Journal of Earth Science2016，27，3： | 8 |
| 11 | Research and application of kapok fiber as an absorbing material: A mini review显示文摘Kapok fiber corresponds to the seed hairs of the kapok tree(Ceiba pentandra), and is a typical cellulosic fiber with the features of thin cell wall, large lumen, low density and hydrophobic–oleophilic properties. As a type of renewable natural plant fiber, kapok fiber is abundant,biocompatible and biodegradable, and its full exploration and potential application have received increasing attention in both academic and industrial fields. Based on the structure and properties of kapok fiber, this review provides a summary of recent research on kapok fiber including chemical and physical treatments, kapok fiber-based composite materials, and the application of kapok fiber as an absorbent material for oils, metal ions, dyes, and sound,with special attention to its use as an oil-absorbing material, one predominant application of kapok fiber in the coming future. | Yian Zheng Jintao Wang Yongfeng Zhu Aiqin Wang | 2015 | Journal of Environmental Sciences2015，27，1： | 7 |
| 12 | Review:Recent advances in multisensor multitarge11racking using random finite set显示文摘In this study,we provide an overview of recent advances in multisensor multitarget tracking based on the random finite set(RFS)approach.The fusion that plays a fundamental role in multisensor filtering is classified into data-level multitarget measurement fusion and estimate-level multitarget density fusion,which share and fuse local measurements and posterior densities between sensors,respectively.Important properties of each fusion rule including the optimality and sub-optimality are presented.In particulax,two robust multitarget density-averaging approaches,arithmetic-and geometric-average fusion,are addressed in detail for various RFSs.Relevant research topics and remaining challenges are highlighted. | Kai DA Tiancheng LI Yongfeng ZHU Hongqi FAN Qiang FU | 2021 | Frontiers of Information Technology & Electronic Engineering2021，22，1： | 5 |
| 13 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 14 | Corrosion Behaviors of Nitride Coatings on Titanium Alloy in NaCl-Induced Hot Corrosion显示文摘TiN and TiAlN coatings were deposited by arc ion plating on titanium alloys to study their hot corrosion resistance when they were exposed to NaCl at 600℃.The microstructure and corrosion behaviors of nitride coatings were studied using scanning electron microscope,X-ray diffraction,electro-probe microanalyzer and X-ray photoelectron spectroscopy.The results showed that nitride coatings with the different compositions and the ones with the same composition but different thicknesses presented different hot corrosion resistance.TiN and thin TiAlN coatings showed poor corrosion resistance.Serious internal oxidation attacked the alloy substrate.Their corrosion products were mainly consisted of non-protective TiO2 and sodium salt.By contrast,the thick TiAlN coating presented outstanding corrosion resistance.Besides sodium salt,the corrosion products were composed of protective Al_(2)O_(3).The increasing thickness of TiAlN significantly enhanced the hot corrosion resistance.The corrosion mechanisms of alloy,TiN and TiAlN coatings were discussed in detail. | Mingming Zhang Yipeng Feng Yahui Wang Yunsong Niu Li Xin Yongfeng Li Jianxiu Su Shenglong Zhu Fuhui Wang | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，10： | 3 |
| 15 | Particle swarm optimization and its application to seismic inversion of igneous rocks显示文摘In order to improve the fine structure inversion ability of igneous rocks for the exploration of underlying strata, based on particle swarm optimization(PSO), we have developed a method for seismic wave impedance inversion. Through numerical simulation, we tested the effects of different algorithm parameters and different model parameterization methods on PSO wave impedance inversion, and analyzed the characteristics of PSO method. Under the conclusions drawn from numerical simulation, we propose the scheme of combining a cross-moving strategy based on a divided block model and high-frequency filtering technology for PSO inversion. By analyzing the inversion results of a wedge model of a pitchout coal seam and a coal coking model with igneous rock intrusion, we discuss the vertical and horizontal resolution, stability and reliability of PSO inversion. Based on the actual seismic and logging data from an igneous area, by taking a seismic profile through wells as an example, we discuss the characteristics of three inversion methods, including model-based wave impedance inversion, multi-attribute seismic inversion based on probabilistic neural network(PNN) and wave impedance inversion based on PSO.And we draw the conclusion that the inversion based on PSO method has a better result for this igneous area. | Yang Haijun Xu Yongzhong Peng Gengxin Yu Guiping Chen Meng Duan Wensheng Zhu Yongfeng Cui Yongfu Wang Xingjun | 2017 | International Journal of Mining Science and Technology2017，27，2： | 3 |
| 16 | International Workshop on "Central Asian Orogenesis and Metallogeny"显示文摘 | Zhu, Yongfeng Li, Yuenchen Xu, Xin | 2008 | Episodes2008，31，3： | 3 |
| 17 | Bioreducible unimolecular micelles based on amphiphilic multiarm hyperbranched copolymers for triggered drug release显示文摘A novel type of bioreducible amphiphilic multiarm hyperbranched copolymer (H40-star-PLA-SS-PEG) based on Boltorn H40 core,poly(L-lactide) (PLA) inner-shell,and poly(ethylene glycol) (PEG) outer-shell with disulfide-linkages between the hydrophobic and hydrophilic moieties was developed as unimolecular micelles for controlled drug release triggered by reduction.The obtained H40-star-PLA-SS-PEG was characterized in detail by nuclear magnetic resonance (NMR),Fourier transform infrared (FTIR),gel permeation chromatography (GPC),differential scanning calorimeter (DSC),and thermal gravimetric analysis (TGA).Transmission electron microscopy (TEM) and dynamic light scattering (DLS) analyses suggested that H40-star-PLA-SS-PEG formed stable unimolecular micelles in aqueous solution with an average diameter of 19 nm.Interestingly,these micelles aggregated into large particles rapidly in response to 10 mM dithiothreitol (DTT),most likely due to shedding of the hydrophilic PEG outer-shell through reductive cleavage of the disulfide bonds.As a hydrophobic anticancer model drug,doxorubicin (DOX) was encapsulated into these reductive unimolecular micelles.In vitro release studies revealed that under the reduction-stimulus,the detachment of PEG outer-shell in DOX-loaded micelles resulted in a rapid drug release.Flow cytometry and confocal laser scanning microscopy (CLSM) measurements indicated that these DOX-loaded micelles were easily internalized by living cells.Methyl tetrazolium (MTT) assay demonstrated a markedly enhanced drug efficacy of DOX-loaded H40-star-PLA-SS-PEG micelles as compared to free DOX.All of these results show that these bioreducible unimolecular micelles are promising carriers for the triggered intracellular delivery of hydrophobic anticancer drugs. | PANG Yan 1,LIU JinYao 1,SU Yue 1,ZHU BangShang 2,HUANG Wei 1,ZHOU YongFeng 1,ZHU XinYuan 1,2 & YAN DeYue 1 1 School of Chemistry and Chemical Engineering,State Key Laboratory of Metal Matrix Composites,Shanghai Jiao Tong University,Shanghai 200240,China 2 Instrumental Analysis Center,Shanghai Jiao Tong University,Shanghai 200240,China | 2010 | Science China Chemistry2010，53，12： | 3 |
| 18 | 2020 Roadmap on two-dimensional nanomaterials for environmental catalysis显示文摘Environmental catalysis has drawn a great deal ofattention due to its clean ways to produce useful chemicals or carry out some chemical processes.Photocatalysis and electrocatalysis play important roles in these fields.They can decompose and remove organic pollutants from the aqueous environment,and prepare some fine chemicals.Moreover,they also can carry out some important reactions,such as 02 reduction reaction(ORR),O2 evolution reaction(OER),H2 evolution reaction(HER),CO2 reduction reaction(C02 RR),and N2 fixation(NRR).For catalytic reactions,it is the key to develop high-performance catalysts to meet the demand fortargeted reactions.In recentyears,two-dimensional(2 D) materials have attracted great interest in environmental catalysis due to their unique layered structures,which offer us to make use of their electronic and structural characteristics.Great progress has been made so far,including graphene,black phosphorus,oxides,layered double hydroxides(LDHs),chalcogenides,bismuth-based layered compounds,MXenes,metal organic frameworks(MOFs),covalent organic frameworks(COFs),and others.This content drives us to invite many famous groups in these fields to write the roadmap on two-dimensional nanomaterials for environmental catalysis.We hope that this roadmap can give the useful guidance to researchers in future researches,and provide the research directions. | Yulu Yang Mingguang Wu Xingwang Zhu Hui Xu Si Ma Yongfeng Zhi Hong Xia Xiaoming Liu Jun Pan Jie-Yinn Tang Siang-Piao Chai Leonardo Palmisano Francesco Parrino Junli Liu Jianzhong Ma Ze-Lin Wang Ling Tan Yu-Fei Zhao Yu-Fei Song Pardeep Singh Pankaj Raizada Deli Jiang Di Li R.A.Geioushy Jizhen Ma Jintao Zhang Song Hu Rongjuan Feng Gang Liu Minghua Liu Zhenhua Li Mingfei Shao Neng Li Jiahe Peng Wee-Jun Ong Nikolay Kornienko Zhenyu Xing Xiujun Fan Jianmin Ma | 2019 | Chinese Chemical Letters2019，30，12： | 2 |
| 19 | A closed-form solution for a double infinite Euler-Bernoulli beam on a viscoelastic foundation subjected to harmonic line load显示文摘The dynamic response of a double infinite beam system connected by a viscoelastic foundation under the harmonic line load is studied. The double infinite beam system consists of two identical and parallel beams, and the two beams are infinite elastic homogeneous and isotropic. A viscoelastic layer connects the two beams continuously. To decouple the two coupled equations governing the response of the double infinite beam system, a variable substitution method is introduced. The frequency domain solutions of the decoupled equations are obtained by using Fourier transforms as well as Laplace transforms successively. The time domain solution in the generalized integral form are then obtained by employing the corresponding inverse transforms, i.e. Fourier transform and inverse Laplace transform. The solution is verified by numerical examples, and the effects of parameters on the response are also investigated. | Li Bing Cheng Yongfeng Zhu Zhaoqing Zhang Fuyou | 2019 | Earthquake Engineering and Engineering Vibration2019，18，1： | 2 |
| 20 | Requirement and Development of Hydrogel Micromotors towards Biomedical Applications显示文摘With controllable size,biocompatibility,porosity,injectability,responsivity,diffusion time,reaction,separation,permeation,and release of molecular species,hydrogel microparticles achieve multiple advantages over bulk hydrogels for specific biomedical procedures.Moreover,so far studies mostly concentrate on local responses of hydrogels to chemical and/or external stimuli,which significantly limit the scope of their applications.Tetherless micromotors are autonomous microdevices capable of converting local chemical energy or the energy of external fields into motive forces for self-propelled or externally powered/controlled motion.If hydrogels can be integrated with micromotors,their applicability can be significantly extended and can lead to fully controllable responsive chemomechanical biomicromachines.However,to achieve these challenging goals,biocompatibility,biodegradability,and motive mechanisms of hydrogel micromotors need to be simultaneously integrated.This review summarizes recent achievements in the field of micromotors and hydrogels and proposes next steps required for the development of hydrogel micromotors,which become increasingly important for in vivo and in vitro bioapplications. | Xinyi Lin Borui Xu Hong Zhu Jinrun Liu Alexander Solovev Yongfeng Mei | 2020 | Research2020，，1： | 2 |
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