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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Transplantation of collagen scaffold with autologous bone marrow mononuclear cells promotes functional endometrium reconstruction via downregulating ΔNp63 expression in Asherman's syndrome显示文摘Asherman's syndrome(AS) is a common disease that presents endometrial regeneration disorder. However, little is known about its molecular features of this aregenerative endometrium in AS and how to reconstruct the functioning endometrium for the patients with AS. Here, we report that ΔNp63 is significantly upregulated in residual epithelial cells of the impaired endometrium in AS; the upregulated-ΔNp63 induces endometrial quiescence and alteration of stemness. Importantly, we demonstrate that engrafting high density of autologous bone marrow mononuclear cells(BMNCs) loaded in collagen scaffold onto the uterine lining of patients with AS downregulates ΔNp63 expression, reverses ΔNp63-induced pathological changes, normalizes the stemness alterations and restores endometrial regeneration. Finally, five patients achieved successful pregnancies and live births. Therefore, we conclude that ΔNp63 is a crucial therapeutic target for AS. This novel treatment significantly improves the outcome for the patients with severe AS. | Guangfeng Zhao Yun Cao Xianghong Zhu Xiaoqiu Tang Lijun Ding Haixiang Sun Juan Li Xinan Li Chenyan Dai Tong Ru Hui Zhu Jingjie Lu Caimei Lin Jingmei Wang Guijun Yan Huiyan Wang Lei Wang Yimin Dai Bin Wang Ruotian Li Jianwu Dai Yan Zhou Yali Hu | 2017 | Science China(Life Sciences)2017，60，4： | 39 |
| 3 | Upregulation of CD81 in trophoblasts induces an imbalance of Treg/Th17 cells by promoting IL-6 expression in preeclampsia显示文摘The disturbance of maternal immune tolerance to a semiallogeneic fetus is recognized as one of the key pathologies of preeclampsia(PE),in which an imbalance between the inflammation-limiting regulatory T cells(Tregs)and the inflammationmediating Th17 cells plays an essential role.Previously,we reported that the abnormal upregulation of tetraspannin CD81 in trophoblast cells(fetal component)participated in the pathogenesis of PE.However,as one of the potential immune regulatory molecules,whether CD81 induces PE by interfering with the balance of the maternal immune system has not yet been clarified.Thus,we investigated the relationship between the upregulation of CD81 in trophoblast cells and the imbalance of Treg and Th17 cells in mothers.Here,we demonstrated that upregulation of CD81 in trophoblast cells was accompanied by a decrease in Treg cells and an increase in Th17 cells in both the basal plate(placental maternal side)and peripheral blood of patients with PE.In vitro culture of naïve T cells with medium from the CD81-overexpressing trophoblast cell line HTR-8 resulted in enhanced differentiation of T cells into Th17 cells and decreased the formation of Tregs,which was dependent on the paracrine signaling of IL-6 in trophocytes,induced by CD81.In a CD81-induced PE rat model,we found a significant shift of T cell differentiation towards Th17 cells,and administration of IL-6 antibody mitigated the PE phenotype and the imbalance of the Treg/Th17 cells.These results define a vital regulatory cascade involving trophocyte-derived CD81,IL-6,and maternal Treg/Th17 cells in the pathogenesis of PE and suggests new therapeutic approaches based on CD81 and IL-6 downregulation to prevent human PE. | Hailin Ding Yimin Dai Yi Lei Zhiyin Wang Dan Liu Ruotian Li Li Shen Ning Gu Mingming Zheng Xiangyu Zhu Guangfeng Zhao Yali Hu | 2019 | Cellular & Molecular Immunology2019，16，3： | 15 |
| 4 | CAS FGOALS-f3-L Model Datasets for CMIP6 Historical Atmospheric Model Intercomparison Project Simulation显示文摘The outputs of the Chinese Academy of Sciences(CAS) Flexible Global Ocean–Atmosphere–Land System(FGOALS-f3-L) model for the baseline experiment of the Atmospheric Model Intercomparison Project simulation in the Diagnostic,Evaluation and Characterization of Klima common experiments of phase 6 of the Coupled Model Intercomparison Project(CMIP6) are described in this paper. The CAS FGOALS-f3-L model, experiment settings, and outputs are all given. In total,there are three ensemble experiments over the period 1979–2014, which are performed with different initial states. The model outputs contain a total of 37 variables and include the required three-hourly mean, six-hourly transient, daily and monthly mean datasets. The baseline performances of the model are validated at different time scales. The preliminary evaluation suggests that the CAS FGOALS-f3-L model can capture the basic patterns of atmospheric circulation and precipitation well, including the propagation of the Madden–Julian Oscillation, activities of tropical cyclones, and the characterization of extreme precipitation. These datasets contribute to the benchmark of current model behaviors for the desired continuity of CMIP. | Bian HE Qing BAO Xiaocong WANG Linjiong ZHOU Xiaofei WU Yimin LIU Guoxiong WU Kangjun CHEN Sicheng HE Wenting HU Jiandong LI Jinxiao LI Guokui NIAN Lei WANG Jing YANG Minghua ZHANG Xiaoqi ZHANG | 2019 | Advances in Atmospheric Sciences2019，36，8： | 12 |
| 5 | NUMERICAL SIMULATION OF FEEDSTOCK MELT FILLING IN A CYLINDRICAL CAVITY WITH SOLIDIFICATION IN POWDER INJECTION MOLDING显示文摘INTRODUCTIONPowderinjectionmolding(PIM)isaprocesingrouteforfabricatingmetalorceramiccomponentswithcomplexshapeandhighperfor?.. | Qu Xuanhui, Li Yimin, Yue Hongsheng, Mao Jinying, Zhu Lei and Huang Baiyun State Key Laboratory for Powder Metallurgy, Central South University of Technology, Changsha 410083, P. R. China | 1998 | 中国有色金属学会会刊:英文版1998，8，4： | 9 |
| 6 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 7 | Secondary Solidification Behaviour of AA8006 Alloy Prepared by Suction Casting显示文摘Solidification behaviour of AA8006 aluminium alloy in suction casting has been investigated by field emission scanning electron microscopy with energy dispersive spectroscopy (EDS). It is found that there is a secondary solidification process of the remaining liquid in located region of α-Al dendrites, and the cooling rate in?uences not only the solidification of the primary α-Al dendrite, but also the secondary solidification process of the remaining liquid. With the primary solidification being responsible for the formation of the relatively large α- Al dendrite, a fine and homogeneous microstructure is observed in the secondary solidification. Furthermore, because of the presence of the fine microstructure, the eutectic reaction is confined into small intergranular areas, inducing the formation of the laminar eutectic phase in the primary solidification region and fibrous eutectic phase in the secondary solidification region. EDS analysis shows that the content of Fe is higher in the secondary solidification region, and the enrichment of the solute element further confirms the existence of the secondary solidification. | Zhongwei Chen Hailing Zhang Yimin Lei | 2011 | Journal of Materials Science & Technology2011，27，9： | 5 |
| 8 | Radical versus conservative surgical treatment of liver hydatid cysts: a meta-analysis显示文摘 | Qing Pang Hao Jin Zhongran Man Yong Wang Song Yang Zongkuang Li Yimin Lu Huichun Liu Lei Zhou | 2018 | Frontiers of Medicine2018，12，3： | 4 |
| 9 | On global asymptotic controllability of planar affine nonlinear systems显示文摘In this paper, we present a necessary and sufficient condition for globally asymptotic controllability of the general planar affine nonlinear systems with single-input. This result is obtained by introducing a new method in the analysis, which is based on the use of some basic results in planar topology and in the geometric theory of ordinary differential equations. | SUN Yimin GUO Lei | 2005 | Science in China(Series F)2005，48，6： | 4 |
| 10 | CAS FGOALS-f3-L Model Datasets for CMIP6 GMMIP Tier-1 and Tier-3 Experiments显示文摘The Chinese Academy of Sciences(CAS)Flexible Global Ocean Atmosphere Land System(FGOALS-f3-L)model datasets prepared for the sixth phase of the Coupled Model Intercomparison Project(CMIP6)Global Monsoons Model Intercomparison Project(GMMIP)Tier-1 and Tier-3 experiments are introduced in this paper,and the model descriptions,experimental design and model outputs are demonstrated.There are three simulations in Tier-1,with different initial states,and five simulations in Tier-3,with different topographies or surface thermal status.Specifically,Tier-3 contains four orographic perturbation experiments that remove the Tibetan Iranian Plateau,East African and Arabian Peninsula highlands,Sierra Madre,and Andes,and one thermal perturbation experiment that removes the surface sensible heating over the Tibetan Iranian Plateau and surrounding regions at altitudes above 500 m.These datasets will contribute to CMIP6’s value as a benchmark to evaluate the importance of long-term and short-term trends of the sea surface temperature in monsoon circulations and precipitation,and to a better understanding of the orographic impact on the global monsoon system over highlands. | Bian HE Yimin LIU Guoxiong WU Qing BAO Tianjun ZHOU Xiaofei WU Lei WANG Jiandong LI Xiaocong WANG Jinxiao LI Wenting HU Xiaoqi ZHANG Chen SHENG and Yiqiong TANG | 2020 | Advances in Atmospheric Sciences2020，37，1： | 4 |
| 11 | Comparisons of the temperature and humidity profiles of reanalysis products with shipboard GPS sounding measurements obtained during the 2018 Eastern Indian Ocean Open Cruise显示文摘本研究利用2018年春季东印度洋科学考察航次采集的GPS探空数据集,分析了三套再分析资料(JRA-55、MERR2和FGOALS-f2)对赤道东印度洋对流层中低层大气温湿廓线的模拟能力。结果表明:JRA-55和MERRA2能合理地再现850-600hPa之间的温度廓线的特征,最大偏差小于0.5度,但在850hPa以下的偏差增大,最底层的偏差分别达到了2和1.5度;两套再分析资料对850-600hPa之间的湿度扩线也具备较好的再现能力,但在850hPa以下JRA55和MERRA2再分析资料高估了相对湿度,最大湿度偏差可达15%。相对而言,FGOALS-f2分析资料对温度廓线再现能力最好,边界层内的温度偏差明显小于其它两套再分析资料;但FGOALS-f2也存在整层偏湿的问题,最大偏差在600hPa附近,误差接近20%。 | WANG Lei BAO Qing LI Jinxiao WANG Dongxiao LIU Yimin WU Guoxiong WU Xiaofei | 2019 | Atmospheric and Oceanic Science Letters2019，12，3： | 3 |
| 12 | Formation of mono-dispersed droplets with electric periodic dripping regime in electrohydrodynamic(EHD) atomization显示文摘The formation of controllable size and dripping frequency in electrohydrodynamic(EHD)atomization with electric periodic dripping regime are of much interest and importance because of significant and wide applications,such as micro-encapsulation and ink-printing.In the present study,the experimental and theoretical works were carried out to explore droplet formation in periodic dripping regime in presence of an electric field.The dimensionless electric charge carried by each droplet produced is smaller than the 50%of critical value of the Rayleigh limit,where charge-to-mass ratio of droplets was obtained through the deflection distance in the presence of an electric field.The droplet in electric periodic dripping regime usually undergoes oscillating deformation,and finally forms a spherical droplet below the tip no more than ten times out diameter of tube.The droplet size tens of microns to one hundreds of microns decreases with an increase in applied potential.In the electric dripping mode,droplets size is independent of flow rate and affected by flow rate due to adsorption of surface active species in micro-dripping.The simplified model to predict droplets size was derived from the balance of electric,surface tension and gravity forces.The droplets size calculated in good agreement with the experiments.Meanwhile,the dripping frequency of droplets with rang of a few to several hundred hertz obtained from timeresolved images is highly dependent of liquid flow rate and electric potential.The largest dripping frequency was predicted and in reasonable agreement with the experimental results.In electric periodic dripping regime drop-on-demand droplets in size and dripping frequency further our understanding on the formation of identical droplets and are beneficial to many practical applications. | Zhentao Wang Qisi Wang Yaosheng Zhang Yimin Jiang Lei Xia | 2020 | Chinese Journal of Chemical Engineering2020，28，5： | 2 |
| 13 | 基于转录组denovo拼接鉴定辣椒(Capsicum frutescens)中辣椒素生物合成相关基因显示文摘辣椒素是由辣椒果实产生的一组化合物,被广泛应用于许多领域,尤其是医药行业。辣椒素生物合成途径还没有被清楚地确定。为了解更多辣椒素生物合成的知识,我们对辣椒(Capsicum frutescens L.)胎座和果皮的混合材料进行了转录组测序。并使用不同的拼接软件对各拼接参数的影响进行了评估,最终获得了转录组数据de novo拼接的最佳策略之一。我们利用Trinity软件得到共54 045条高质量unigenes(转录物)。约92.65%的unigenes与马铃薯、番茄和辣椒(C.annuum)ESTs数据库公共蛋白序列和基因组有相似性。我们预测到了3个新的结构基因(DHAD,TD,PAT),填补了由Mazourek提出的辣椒素分子合成途径中的空缺,并且以KEGG(京东基因与基因组百科全书)分析为基础,鉴定到了参与辣椒素生物合成新的候选基因。大量的SSR(简单重复序列)和SNP(单核苷酸多态性)标记在C.frutescens和C.annuum序列中被预测到,这些标记可在识别辣椒群体多态性方面提供帮助。这些数据将为辣椒素生物合成途径及相关研究提供新的思路。此外,我们的转录组de novo拼接策略也可用于其他大量类似研究中。 | Liu Shaoqun Li Wanshun Wu Yimin Chen Changming Lei Jianjun 高凌云 孔秋生 | 2014 | 辣椒杂志2014，，1： | 2 |
| 14 | 大气所全球25 km气候模式CAS FGOALS-f3-H参加CMIP6 HighResMIP数据介绍显示文摘高分辨率模式比较计划(HighResMIP)是CMIP6中新增的模式间比较计划,旨在关注水平分辨率对气候模拟的影响。本文介绍了中国科学院大气物理研究所全球25km FGOALS-f3-H和100km FGOALS-f3-L模式的基本信息,以及参与HighResMIP的试验设计,强迫数据,数据后处理方法等信息。水平分辨率25km的FGOALS-f3-H模式和100km FGOALS-f3-L模式由标准外强迫场驱动,且分别在1950-2014和2015-50时段进行两组协同试验,试验编号分别为'highresSST-present'及'highresSST-future'。模拟和预估数据集包含多种输出频率:1小时平均,3小时平均,6小时瞬时,日平均和月平均等。评估结果表明:水平分辨率的提高能够显著改进模式在热带气旋、日变化和极端降水的模拟性能。相较于全球100km低分辨率的FGOALS-f3-L,全球25km的FGOALS-f3-H能够更好的刻画热带气旋的生命周期和全球降水的日变化主要特征,特别是能够准确再现亚洲夏季风的降水日变化峰值时间。该数据集的发布将大大促进水平分辨率对气候模拟和预估影响的相关研究。 | BAO Qing LIU Yimin WU Guoxiong HE Bian LI Jinxiao WANG Lei WU Xiaofei CHEN Kangjun WANG Xiaocong YANG Jing ZHANG Xiaoqi | 2020 | Atmospheric and Oceanic Science Letters2020，13，6： | 1 |
| 15 | Investigations and assessment of the landslide hazards of Fengdu county in the reservoir region of the Three Gorges project on the Yangtze River显示文摘 | Shuren Wu Yimin Jin Yongshuang Zhang Jusong Shi Chen Dong Weizhi Lei Ling Shi Chengxuan Tan Daogong Hu | 2004 | Environmental Geology2004，，4： | 1 |
| 16 | 关于CAS FGOALS-f3-L模式中青藏高原地表温度偏差的归因分析显示文摘中国科学院全球海洋-大气-陆地耦合模式(FGOALS-f3-L)参加了耦合模式比较计划的第六阶段(CMIP6)试验,但是其对关键气候敏感地区青藏高原的地表温度的再现能力还不清楚.这项研究用再分析资料CFSR评估了FGOALSf3-L模式对青藏高原地表温度的再现能力.结果表明,FGOALS-f3-L可以合理模拟整个高原上年平均地表温度的空间分布,但低估了整个高原上年平均地表温度.模拟的地表温度在整个高原上冬春季表现为冷偏差,夏秋季表现为暖偏差.基于地表能量平衡方程的进一步定量分析表明,地表反照率反馈(SAF)项极大地贡献了高原西部年平均,冬春季平均地表温度的冷偏差,而对高原东部是暖偏差贡献.与SAF项相比,地表感热项对地表温度偏差的贡献几乎相反,这大大抵消了SAF项引起的偏差.云辐射强迫项对高原东部的年平均和季节平均弱冷偏差有很大贡献.与高估的水蒸气含量有关的长波辐射项造成了夏秋季整个高原上大部分的暖偏差.该研究表明,提高FGOALS-f3-L中的陆面和云过程对降低高原上地表温度偏差至关重要. | Yao Wu Yimin Liu Jiandong Li Qing Bao Bian He Lei Wang Xiaocong Wang Jinxiao Li | 2021 | Atmospheric and Oceanic Science Letters2021，14，1： | 1 |
| 17 | Sex-related changes in tumor consistency in prolactinoma patients after bromocriptine pretreatment显示文摘Objective It has long been reported that prolactinomas treated with bromocriptine increase fibrosis and may affect surgical outcomes.We retrospectively studied 238 consecutive patients with histopathologically confirmed prolactinomas undergoing microsurgery in a single neurosurgery department of Tongji Hospital(Wuhan,China) from 2012 to 2015 in order to evaluate tumor consistency changes after bromocriptine pretreatment and surgical outcomes.Methods We divided the patients into four groups;males in the dopamine agonist(DA) group,females in the DA group,males in the no DA group,and females in the no DA group,and we compared the surgery process,specimen Masson staining,and clinical outcomes of the four groups.According to a previously published classification,the operative notes from an experienced neurosurgeon were reviewed to classify the consistency of tumors as 'fibrous' or 'nonfibrous'.Results No differences in tumor consistency were found in male patients with or without DA treatment.However,in female patients with DA treatment,tumors were likely to be harder in texture than the tumors of female patients without DA treatment.Despite tumor consistency differences between sexes,the tumor biological remission rate was similar between groups,as was the rate of tumor resection.Discussion Our study indicates that preoperative DA therapy impacts tumor consistency in female patients but not male patients.Although the surgical and histopathological outcomes are not influenced,these findings may provide useful information for the choice of operative approach and surgery process for pituitary adenoma. | Yimin Huang Feng Hu Kang Wu Juan Chen Ran Li Hao Xu Ting Lei | 2016 | Oncology and Translational Medicine2016，2，5： | 1 |
| 18 | Positive regulation of migration and invasion by vasodilator-stimulatedphosphoprotein via Rac1 pathway in human breast cancer cells显示文摘 | Guoge Han Biao Fan Yimin Zhang Xuan Zhou Yongping Wang Huimin Dong Yun Wei Shengrong Sun Mingbo Hu Jingwei Zhang Lei Wei | 2008 | Oncology Reports2008，，4： | 1 |
| 19 | Structure and properties of nanostructured A357 alloy produced by melt spinning compared with direct chill ingot显示文摘 | Zhongwei Chen Yimin Lei Haifang Zhang | 2011 | Journal of Alloys and Compounds2011，，27： | 1 |
| 20 | Pyrolysis transformation of ZIF-8 wrapped with polytriazine to nitrogen enriched core-shell polyhedrons carbon for supercapacitor显示文摘This work presents a simple effective strategy to synthesize N-doped and shell-controlled carbon nanocages through a package baking approach.A green approach to synthesize core-shell ZIF-8@PTZ nanoparticles involves zinc contained ZIF-8 core wrapped by a N-enriched polytriazine(PTZ).Synthesized core-shell ZIF-8@PTZ nanoparticles are calcinated to further sublime zinc through PTZ shell and washed by HC1,leaving a porous carbon structure.At the meantime,hollow cavities were introduced into N-doped carbon polyhedrons via the sacrifice of ZIF-8 template(noted as ZIF-8@C/N-x).The electrochemical performance of the ZIF-8@C/N-x as supercapacitor electrode has demonstrated high energy density and specific capacitance,as well as a long-term cycleability showing 92%capacitance retention after 10000 cycles.There is a systematic correlation between micro-/meso-porosity of ZIF-8@C/N-x and their electrochemical performances. | Nuoya Wang Xinhua Huang Lei Zhang Jinsong Hu Yimin Chao Ruikun Zhao | 2021 | Frontiers of Chemical Science and Engineering2021，15，4： | 1 |
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