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| 1 | Influence of Atmospheric Particulate Matter on Ozone in Nanjing,China:Observational Study and Mechanistic Analysis显示文摘Particulate matter with diameters of 2.5 μm or smaller(PM_(2.5)) and ozone(O_3) are major pollutants in the urban atmosphere. PM_(2.5) can affect O_3 by altering the photolysis rate and heterogeneous reactions. However, these two processes and their relative importance remain uncertain. In this paper, with Nanjing in China as the target city, we investigate the characteristics and mechanism of interactions between particles and O_3 based on ground observations and numerical modeling.In 2008, the average concentrations of PM_(2.5) and O_3 at Caochangmen station are 64.6 ± 47.4 μg m^(-3) and 24.6 ± 22.8 ppb,respectively, while at Pukou station they are 94.1 ± 63.4 μg m^(-3) and 16.9 ± 14.9 ppb. The correlation coefficient between PM_(2.5) and O_3 is -0.46. In order to understand the reaction between PM_(2.5) and O_3, we construct a box model, in which an aerosol optical property model, ultraviolet radiation model, gas phase chemistry model, and heterogeneous chemistry model,are coupled. The model is employed to investigate the relative contribution of the aforementioned two processes, which vary under different particle concentrations, scattering capability and VOCs/NOxratios(VOCs: volatile organic compounds;NOx: nitric oxide and nitrogen dioxide). Generally, photolysis rate effect can cause a greater O_3 reduction when the particle concentrations are higher, while heterogeneous reactions dominate O_3 reduction with low-level particle concentrations.Moreover, in typical VOC-sensitive regions, O_3 can even be increased by heterogeneous reactions. In Nanjing, both processes lead to O_3 reduction, and photolysis rate effect is dominant. Our study underscores the importance of photolysis rate effect and heterogeneous reactions for O_3, and such interaction processes should be fully considered in future atmospheric chemistry modeling. | Yawei QU Tijian WANG Yanfeng CAI Shekou WANG Pulong CHEN Shu LI Mengmeng LI Cheng YUAN Jing WANG Shaocai XU | 2018 | Advances in Atmospheric Sciences2018，35，11： | 33 |
| 2 | AOX contamination status and genotoxicity of AOX-bearing pharmaceutical wastewater显示文摘Adsorbable organic halogens(AOX) are a general indicator for the total amount of compounds containing organically bonded halogens. AOX concentrations and components were investigated along the wastewater treatment process in four large-scale pharmaceutical factories of China, and genotoxicity based on the SOS/umu test was also evaluated. The results showed that AOX concentrations in wastewater of four factories ranged from 4.6 to 619.4 mg/L, which were high but greatly different owing to differences in the raw materials and products. The wastewater treatment process removed 50.0%–89.9% of AOX, leaving 1.3–302.5 mg/L AOX in the effluents. Genotoxicity levels ranged between 2.1 and 68.0 μg 4-NQO/L in the raw wastewater and decreased to 1.2–41.2 μg 4-NQO/L in the effluents of the wastewater treatment plants(WWTPs). One of the main products of factory I, ciprofloxacin, was identified as the predominant contributor to its genotoxicity. However, for the other three factories, no significant relationship was observed between genotoxicity and detected AOX compounds. | Yawei Xie Lujun Chen Rui Liu | 2017 | Journal of Environmental Sciences2017，29，2： | 15 |
| 3 | Development of a static test apparatus for evaluating the performance of three PM2.5 separators commonly used in China显示文摘PM2.5 separator directly affects the accuracy of PM2.5 sampling.The specification testing and evaluation for PM2.5 separator is particularly important,especially under China’s wide variation of terrain and climate.In this study,first a static test apparatus based on polydisperse aerosol was established and calibrated to evaluate the performance of the PM2.5 separators.A uniform mixing chamber was developed to make particles mix completely.The aerosol concentration relative standard deviations of three test points at the same horizontal chamber position were less than 0.57%,and the particle size distribution obeyed logarithmic normal distribution with an R2 of 0.996.The flow rate deviation between the measurement and the set point flow rate agreed to within±1.0%in the range of-40 to 50℃.Secondly,the separation,flow and loading characteristics of three cyclone separators(VSCC-A,SCC-A and SCC112)were evaluated using this system.The results showed that the 50%cutoff sizes(D50)of the three cyclones were 2.48,2.47 and 2.44μm when worked at the manufacturer’s recommended flow rates,respectively.The geometric standard deviation(GSD)of the capture efficiency of VSCCA was 1.23,showed a slightly sharper than SCC-A(GSD=1.27),while the SCC112 did not meet the relevant indicator(GSD=1.2±0.1)with a GSD=1.44.The flow rate and loading test had a great effect on D50,while the GSD remained almost the same as before.In addition,the maintenance frequency under different air pollution conditions of the cyclones was summarized according to the loading test. | Peng Du Jianguo Liu Huaqiao Gui Jiaoshi Zhang Tongzhu Yu Jie Wang Yin Cheng Yihuai Lu Yawei Yao Qiang Fu ChihChieh Chen | 2020 | Journal of Environmental Sciences2020，32，1： | 9 |
| 4 | Processes of coastal ecosystem carbon sequestration and approaches for increasing carbon sink显示文摘The oceans are the largest carbon pools on Earth, and play the role of a 'buffer' in climate change. Blue carbon, the carbon(mainly organic carbon) captured by marine ecosystems, is one of the important mechanisms of marine carbon storage.Blue carbon was initially recognized only in the form of visible coastal plant carbon sequestration. In fact, microorganisms(phytoplankton, bacteria, archaea, viruses, and protozoa), which did not receive much attention in the past, account for more than 90% of the total marine biomass and are the main contributors to blue carbon. Chinese coastal seas, equivalent to 1/3 of China's total land area, have a huge carbon sink potential needing urgently research and development. In this paper, we focus on the processes and mechanisms of coastal ocean's carbon sequestration and the approaches for increasing that sequestration. We discuss the structures of coastal ecosystems, the processes of carbon cycle, and the mechanisms of carbon sequestration. Using the evolution of coastal ocean's carbon sinks in sedimentary records over geologic times, we also discuss the possible effects of natural processes and anthropogenic activities on marine carbon sinks. Finally, we discuss the prospect of using carbon sequestration engineering for increasing coastal ocean's carbon storage capacity. | ZHANG Yao ZHAO MeiXun CUI Qiu FAN Wei QI JiaGuo CHEN Ying ZHANG YongYu GAO KunShan FAN JingFeng WANG GuangYi YAN ChongLing LU HaoLiang LUO YaWei ZHANG ZiLian ZHENG Qiang XIAO Wei JIAO NianZhi | 2017 | Science China Earth Sciences2017，60，5： | 6 |
| 5 | Effects of chlortetracycline,Cu and their combination on the performance and microbial community dynamics in swine manure anaerobic digestion显示文摘Swine manure was typical for the combined pollution of heavy metals and antibiotics. The effects of widely used veterinary antibiotic chlortetracycline(CTC), Cu and their combination on swine manure anaerobic digestion performance and microbial community have never been investigated. Thus, four 2 L anaerobic digestion reactors were established including reactor A(control), B(CTC spiked by 0.5 g/kg dry weight, dw), C(Cu spiked by 5 g/kg dw) and D(combination of CTC, 0.5 g/kg dw, and Cu, 5 g/kg dw), and dynamics of bacterial and archaeal community structure was investigated using high throughput sequencing method. Results showed that addition of CTC and Cu separately could increase the total biogas production by21.6% and 15.8%, respectively, while combination of CTC and Cu severely inhibited anaerobic digestion(by 30.3%). Furthermore, corresponding to different stages and reactors, four kinds of microbes including bacteria and archaea were described in detail, and the effects of CTC, Cu and their combination mainly occurred at hydrolysis and acidification phases. The addition of Cu alone changed the dynamics of archaeal community significantly. It was genus Methanomassiliicoccus that dominated at the active methane production for A, B and D, while it was genus Methanobrevibacter and Methanoculleus for C. | Rui Wang Junya Zhang Jibao Liu Dawei Yu Hui Zhong Yawei Wang Meixue Chen Juan Tong Yuansong Wei | 2018 | Journal of Environmental Sciences2018，30，5： | 5 |
| 6 | Nuclear m^(6)A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos显示文摘N^(6)-methyladenosine(m^(6)A)on chromosome-associated regulatory RNAs(carRNAs),including repeat RNAs,plays important roles in tuning the chromatin state and transcription,but the intrinsic mechanism remains unclear.Here,we report that YTHDC1 plays indispensable roles in the self-renewal and differentiation potency of mouse embryonic stem cells(ESCs),which highly depends on the m^(6)A-binding ability.Ythdcl is required for sufficient rRNA synthesis and repression of the 2-cell(2C)transcriptional program in ESCs,which recapitulates the transcriptome regulation by the LINE1 scaffold.Detailed analyses revealed that YTHDC1 recognizes m^(6)A on LINE1 RNAs in the nucleus and regulates the formation of the LINE1-NCL partnership and the chromatin recruitment of KAP1.Moreover,the establishment of H3K9me3 on 2C-related retrotrans-posons is interrupted in Ythdcl-depleted ESCs and inner cell mass(ICM)cells,which consequently increases the transcriptional activities.Our study reveals a role of m^(6)A in regulating the RNA scaffold,providing a new model for the RNA-chromatin cross-talk. | Chuan Chen Wenqiang Liu Jiayin Guo Yuanyuan Liu Xuelian Liu Jun Liu Xiaoyang Dou Rongrong Le Yixin Huang Chong Li Lingyue Yang Xiaochen Kou Yanhong Zhao You Wu Jiayu Chen Hong Wang Bin Shen Yawei Gao Shaorong Gao | 2021 | Protein & Cell2021，12，6： | 4 |
| 7 | Promoted conversion of polysulfides by MoO_2 inlaid ordered mesoporous carbons towards high performance lithium-sulfur batteries显示文摘As polar materials, transition-metal oxides have shown great potentials to improve the adsorption of lithium polysulfides in lithium-sulfur batteries. Herein, a MoO_2-ordered mesoporous carbon (M-OMC)hybrid was designed as the sulfur host, in which MoO_2 is inlaid on the surface of ordered mesoporous carbons that can store active materials and provide fast electron transfer channel due to its ordered pore structure. The MoO_2 can effectively prevent the migration of polysulfides through the chemical adsorption and promote the conversion of polysulfides towards Li-sulfur battery. | Yawei Chen Shuzhang Niu Wei Lv Chen Zhang Quanhong Yang | 2019 | Chinese Chemical Letters2019，30，2： | 4 |
| 8 | Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers显示文摘 | Chen Wu Yuanyuan Xie Feng Gao Yanan Wang Yawei Guo Huanna Tian Yanshuang Li Wufang Fan | 2013 | Gene2013，，1： | 2 |
| 9 | Applications of Metal–Organic Frameworks and Their Derivatives in Electrochemical CO_(2)Reduction显示文摘Electrochemically reducing CO_(2)to more reduced chemical species is a promising way that not only enables the conversion of intermittent energy resources to stable fuels,but also helps to build a closed-loop anthropogenic carbon cycle.Among various electrocatalysts for electrochemical CO_(2)reduction,multifunctional metal–organic frameworks(MOFs)have been employed as highly efficient and selective heterogeneous electrocatalysts due to their ultrahigh porosity and topologically diverse structures.Up to now,great progress has been achieved in the design and synthesis of highly active and selective MOF-related catalysts for electrochemical CO_(2)reduction reaction(CO_(2)RR),and their corresponding reaction mechanisms have been thoroughly studied.In this review,we summarize the recent progress of applying MOFs and their derivatives in CO_(2)RR,with a focus on the design strategies for electrocatalysts and electrolyzers.We first discussed the reaction mechanisms for different CO_(2)RR products and introduced the commonly applied electrolyzer configurations in the current CO_(2)RR system.Then,an overview of several categories of products(CO,HCOOH,CH_(4),CH_(3)OH,and multi-carbon chemicals)generated from MOFs or their derivatives via CO_(2)RR was discussed.Finally,we offer some insights and perspectives for the future development of MOFs and their derivatives in electrochemical CO_(2)reduction.We aim to provide new insights into this field and further guide future research for large-scale applications. | Chengbo Li Yuan Ji Youpeng Wang Chunxiao Liu Zhaoyang Chen Jialin Tang Yawei Hong Xu Li Tingting Zheng Qiu Jiang Chuan Xia | 2023 | Nano-Micro Letters2023，15，8： | 2 |
| 10 | Low-firing,temperature stable and improved microwave dielectric properties of ZnO-TiO_(2)-Nb_(2)O_(5) composite ceramics显示文摘This article presents low-firing,low-loss and temperature stable ZnO-TiO_(2)-Nb_(2)O_(5) microwave dielectric composite ceramics with the assistance of lithium borosilicate(LBS)and zinc borosilicate(ZBS)glass frits.There is a liquid phase(eutectic mixture)generated by LBS(ZBS)glass,and solid particles could be wetted and dissolved.Therefore,the migrations and rearrangements of particles could be performed.Besides,compared with ceramics undoped with glass frits,lower activation energies(E_(a))of ceramics doped with LBS and ZBS glass suggest that the low-temperature sintering behavior is easier to carry out.The results indicated that LBS and ZBS glass both are effective sintering aids to accelerate the sintering process and improve the microwave dielectric properties of composite ceramics by controlling the phase compositions under low temperature.Combination great properties of ZnO-TiO_(2)-Nb_(2)O_(5) ceramics were obtained when sintered at 900℃ for 4 h:ε_(r)=36.7,Q×f=20,000 GHz,τ_(f)=7 ppm/℃. | Hongyu Yang Shuren Zhang Yawei Chen Hongcheng Yang Zixuan Fang Ying Yuan Enzhu Li | 2019 | Journal of Materiomics2019，5，3： | 2 |
| 11 | Fish red blood cells express immune genes and responses显示文摘The erythrocytes or red blood cells(RBCs)and leucocytes or white blood cells(WBCs)are the most abundant cell types in the circulatory system of vertebrates.The RBCs are responsible for gas exchange while WBCs are solely involved with immunity.In this study,we present evidence that fish RBCs despite their respiratory role they also express immune-related genes and responses in the teleost fish,Nile tilapia(Oreochromis niloticus).Fluorescent staining identified the presence of numerous mitochondria and lysosomes in tilapia RBCs.RNA sequencing of tilapia RBCs and WBCs led to the assembly and annotation of 20.876 transcripts of which 1017 and 3628 transcripts were specific to RBCs and WBCs,respectively.Pairwise sequence comparisons identified 3251 transcripts that were significantly differential expressed of which 707(21.75%)were up-regulated and 2544(78.25%)down-regulated in RBCs when compared to WBCs.809 transcripts were assigned to 16 immune system pathways,21 and 163 transcripts were specifically expressed in tilapia RBCs and WBCs respectively,and 23 and 233 transcripts were highly expressed in RBCs and WBCs respectively.Expression of 7 immune genes(interferon regulatory factors(irf)1e5 and 9 and tlr3)in both WBCs and RBCs was validated by RT-PCR analysis.Quantitative real-time PCR revealed that all genes were up-regulated in poly(I:C)-challenged WBCs and irf(1,3,4,and 9)and tlr3 were also significantly up-regulated in poly(I:C)-challenged RBCs.Therefore,fish RBCs expressed immunity genes and responses and they may play a complementary role in vertebrate immunity. | Yawei Shen Dan Wang Jinliang Zhao Xiaowu Chen | 2018 | Aquaculture and Fisheries2018，3，1： | 2 |
| 12 | Effect of Nano Carbon Black and Graphite Flake on Properties of Low Carbon Al2O3-C Refractories显示文摘Low carbon Al_2O_3-C refractories specimens were prepared with tabular alumina( 3. 0- 1. 0,1. 0- 0. 5,0. 6- 0. 2,≤0. 3,≤0. 045 and ≤0. 02 mm),active alumina micropowder( ≤2 μm) and silicon( ≤0. 045mm) as main raw materials. Nano carbon black( N220) and natural graphite flake( ≤0. 074 mm)were adopted as the carbon sources. The specimens were treated at 800,1 000,1 200 and 1 400 ℃ under coke embedded atmosphere. The effects of additions of nano carbon black and graphite flake on mechanical properties and thermal shock resistance of the specimens were studied. Their mechanical properties were measured by threepoint bending test and thermal shock resistance was determined by water quenching method. The phase composition of the specimens was analyzed with X-ray diffraction and microstructures were observed through FESEM.The results reveal that:(1) the strengths of Al_2O_3-C refractories with these two carbon sources show no big differences when coked at lower than 1 000 ℃; when coked at over 1 200 ℃,the strengths of the specimens with graphite added are much higher than those of the specimens containing carbon black due to much more silicon carbide whiskers formed;( 2) since the nano carbon black has small particle size,they can be filled into interstice of Al_2O_3 particles to form the nano carbon network structure,absorbing and relieving the thermal stressgenerated from expansion and contraction and reducing the thermal expansion coefficient of the specimens,thus their thermal shock resistance is better than that of the specimens containing graphite;( 3) low carbon Al_2O_3-C refractories with good mechanical properties and excellent thermal shock resistance can be prepared with combination of nano carbon black and graphite flake. | LIAO Ning LI Yawei SANG Shaobai CHEN Songlin ZENG Luju | 2016 | China's Refractories2016，25，2： | 2 |
| 13 | A promising trend for field information collection:An air-ground multi-sensor monitoring system显示文摘Timely identifying and quantifying significant spatial and temporal variability in agricultural field has been a crucial factor for improving agricultural production and management.This paper focuses on the mainstream techniques and applications can be adopted to improve the field information collection method.In this paper,the development of wireless sensor networks(WSNs)and remote sensing(RS)technology were reviewed,especially the micro unmanned aerial vehicle(mUAV)-based WSNs and mUAV-based RS by analyzing its applications in field information collection,and pointed out its existing benefits and limitations.A system encompassed multiple technique approaches was proposed in this paper which is called air-ground multi-sensor monitoring system.With the diversification methods of in-field information collection and the improvement of detection precision,an infield information collection system will play an important role in controlling the farming operations of mechanized agriculture and optimizing the management of agricultural machinery group.In the future,the combination of mUAV,WSNs and RS for crop and soil monitoring will become a powerful tool to obtain field information,increase production,optimize the overall farming practices and input of resources and provide comprehensive reference for the study of soil-crops-machine relationships. | Yawei Zhang Du Chen Shumao Wang Lei Tian | 2018 | Information Processing in Agriculture2018，5，2： | 2 |
| 14 | Shear strength of an unsaturated weakly expansive soil显示文摘To study the weakly expansive clay obtained from a slope along Wuhan-Shiyan expressway in Hubei Province,soil-water property tests and some unsaturated triaxial tests with suction control were conducted,and the soil-water retention curve(SWRC) and unsaturated shear strength of this soil were obtained.Results show that the air-entry suction and the residual degree of saturation of the tested soil are 106 kPa and 8%,respectively.The boundary effect zone and the transition zone can be identified on the desorption curve,but the residual zone is not so obvious.The unsaturated shear strength increases as suction increases within the range of controlled suction in the test,and friction angle,~b,in the triaxial shear test is 17.6°.Based on the results,constitutive models for predicting the unsaturated shear strength using the SWRC were evaluated,and comparisons between prediction and measurement were made.It is concluded that for engineering purpose,the constitutive model should be carefully selected based on soil properties when predicting the unsaturated shear strength using the SWRC. | Weimin Ye Yawei Zhang Bao Chen Xiuhan Zhou Qiang Xie | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，2： | 2 |
| 15 | Multiplex genome editing using a dCas9-cytidine deaminase fusion in Streptomyces显示文摘CRISPR/Cas-mediated genome editing has greatly facilitated the study of gene function in Streptomyces. However, it could not be efficiently employed in streptomycetes with low homologous recombination(HR) ability. Here, a deaminase-assisted base editor d Cas9-CDA-ULstr was developed in Streptomyces, which comprises the nuclease-deficient Cas9(dCas9), the cytidine deaminase from Petromyzon marinus(PmCDA1), the uracil DNA glycosylase inhibitor(UGI) and the protein degradation tag(LVA tag). Using d Cas9-CDA-ULstr , we achieved single-, double-and triple-point mutations(cytosine-to-thymine substitutions)at target sites in Streptomyces coelicolor with efficiency up to 100%, 60% and 20%, respectively. This base editor was also demonstrated to be highly efficient for base editing in the industrial strain, Streptomyces rapamycinicus, which produces the immunosuppressive agent rapamycin. Compared with base editors derived from the cytidine deaminase rAPOBEC1, the PmCDA1-assisted base editor dCas9-CDA-ULstr could edit cytosines preceded by guanosines with high efficiency, which is a great advantage for editing Streptomyces genomes(with high GC content). Collectively, the base editor dCas9-CDA-ULstr could be employed for efficient multiplex genome editing in Streptomyces. Since the d Cas9-CDA-ULstr -based genome editing is independent of HR-mediated DNA repair, we believe this technology will greatly facilitate functional genome research and metabolic engineering in Streptomyces strains with weak HR ability. | Yawei Zhao Jinzhong Tian Guosong Zheng Jun Chen Chuanwen Sun Zhongyi Yang Andrei A.Zimin Weihong Jiang Zixin Deng Zhijun Wang Yinhua Lu | 2020 | Science China(Life Sciences)2020，63，7： | 2 |
| 16 | Fuzzy Approach to Preaulifying Construction Contractors 显示文摘 | Yawei Li Xiangtian Nie Shouyu Chen | 2007 | Construction Engineering and Management2007，，7： | 1 |
| 17 | PC4 serves as a negative regulator of skin wound healing in mice显示文摘Background:Human positive cofactor 4(PC4)was initially characterized as a multifunctional transcriptional cofactor,but its role in skin wound healing is still unclear.The purpose of this study was to explore the role of PC4 in skin wound healing through PC4 knock-in mouse model.Methods:A PC4 knock-in mouse model(PC4^(+/+))with a dorsal full-thickness wound was used to investigate the biological functions of PC4 in skin wound healing.Quantitative PCR,Western blot analysis and immunohistochemistry were performed to evaluate the expression of PC4;Sirius red staining and immunofluorescence were performed to explore the change of collagen deposition and angiogenesis.Proliferation and apoptosis were detected using Ki67 staining and TUNEL assay.Primary dermal fibroblasts were isolated from mouse skin to perform cell scratch experiments,cck-8 assay and colony formation assay.Results:The PC4^(+/+)mice were fertile and did not display overt abnormalities but showed an obvious delay in cutaneous healing of dorsal skin.Histological staining showed insufficient re-epithelialization,decreased angiogenesis and collagen deposition,increased apoptosis and decreased cell proliferation in PC4^(+/+)skin.Our data also showed decreased migration rate and proliferation ability in cultured primary fibroblasts from PC4^(+/+)mice in vitro.Conclusions:This study suggests that PC4 might serve as a negative regulator of skin wound healing in mice. | Fengying Liao Long Chen Peng Luo Zhongyong Jiang Zelin Chen Ziwen Wang Chi Zhang Yu Wang JintaoHe Qing Wang Yawei Wang Lang Liu Yu Huang Huilan Wang Qingzhi Jiang Min Luo YiboGan Yunsheng Liu Yang Wang Jie Wu Wentao Xie Zhuo Cheng Yali Dai Jialun Li Zujuan Liu Fan Yang Chunmeng Shi | 2020 | Burns & Trauma2020，8，1： | 1 |
| 18 | Predicting thermal instability in a closed loop pulsating heat pipe system显示文摘 | Chen Pinghei Yawei Lee Tienli Chang | 2009 | Applied Thermal Engineering2009，，29： | 1 |
| 19 | Carbothermic reduc-tion synthesis of Ti ( C,N) powder in the presence of moltensalt 显示文摘 | Chen Xilai Li Yuanbing Li Yawei | 2008 | Ceramics International2008，34，5： | 1 |
| 20 | Fuzzy approach to prequalifying construction contractors 显示文摘 | Li Yawei Nie Xiangtian Chen Shouyu | 2007 | Journal of Construction Engineering and Management2007，133，1： | 1 |
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