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| 1 | Meanders of the Jialing River in China: Morphology and formation显示文摘As a fundamental category of river system, comparisons in diverse regions and types with quantitative parameters on meander morphology will help to distinguish different characteristics and approach formations and evolutions. It also can provide scientific basis of geomorphology for their protections and exploitation of the meander resources. Based on the images of Google Earth, meanders’ parame- ters are proposed and then measured and calculated. The result suggests that incised meanders in the Jialing River are among the most complex, irregular and sinuous channels. Special river gradient, geological structures, strata and lithology, backwater effect of landform are key factors to shape me- anders of the Jialing River. The evolution of meander in the Jialing River obeys the principle of mini- mum-maximum energy dissipation. Easy acquisitions of remote sensing data make regional and global comparisons possible, and then the differences of formations can be explored. The morphology can probably provide an evidence of antecedent river and demonstrate the channel incisions and crustal uplifts. Meander core in Chinese is named after the isolated hills in the Jialing River. The incised me- ander is a kind of resource and needs to be protected. | ZHANG Bin AI NanShan HUANG ZhengWen YI ChengBo QIN FaCao | 2008 | Chinese Science Bulletin2008，53，2： | 6 |
| 2 | Suppressing interfacial side reactions of zinc metal anode via isolation effect toward high-performance aqueous zinc-ion batteries显示文摘Aqueous zinc(Zn)-ion batteries(AZIBs)are one of the most promising large-scale energy storage devices because of the excellent features of zinc metal anodes,including high theoretical capacity(5,855 mAh·cm^(–3)and 820 mAh·g^(−1)),high safety,and natural abundance.Nevertheless,the large-scale applications of AZIBs are mainly limited by the severe interfacial side reactions of zinc metal anodes,which results in low plating/stripping Coulombic efficiency and poor cycling stability.To address this issue,we report an artificial Ta_(2)O_(5)protective layer on zinc foil(Ta_(2)O_(5)@Zn)for suppressing side reactions during Zn deposition/stripping.The results of density functional theory calculation and experiments indicate that Ta_(2)O_(5)@Zn anode can inhibit the side reactions between the electrolyte and zinc anode through the isolation effect.Benefiting from this advantage,the symmetric cells with Ta_(2)O_(5)@Zn anode delivered an ultralong lifespan of 3,000 h with a low overpotential at 0.25 mA·cm^(−2)for 0.05 mAh·cm^(−2).Furthermore,the full cells consisting of Ta_(2)O_(5)@Zn anode and MnO_(2)or NH_(4)V_(4)O_(10)cathode all present outstanding electrochemical performance,indicating its high reliability in practical applications.This strategy brings new opportunities for the future development of rechargeable AZIBs. | Feng Tao Kaijia Feng Yong Liu Jiangzhuo Ren Yi Xiong Chengbo Li Fengzhang Ren | 2023 | Nano Research2023，16，5： | 2 |
| 3 | Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways显示文摘 | Chengbo Sun Chun Liang Yusheng Ren Yi Zhen Zhiqing He Hua Wang Hongbing Tan Xiaoming Pan Prof. Dr. Zonggui Wu | 2009 | Basic Research in Cardiology2009，，1： | 1 |
| 4 | Anticarin-β shows a promising antiosteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis显示文摘Unlike healthy, non-transformed cells, the proteostasis network of cancer cells is taxed to produce proteins involved in tumor development. Cancer cells have a higher dependency on molecular chaperones to maintain proteostasis. The chaperonin T-complex protein ring complex(TRiC) contains eight paralogous subunits(CCT1-8), and assists the folding of as many as 10% of cytosolic proteome.TRiC is essential for the progression of some cancers, but the roles of TRiC subunits in osteosarcoma remain to be explored. Here, we show that CCT4/TRiC is significantly correlated in human osteosarcoma,and plays a critical role in osteosarcoma cell survival. We identify a compound anticarin-β that can specifically bind to and inhibit CCT4. Anticarin-β shows higher selectivity in cancer cells than in normal cells. Mechanistically, anticarin-β potently impedes CCT4-mediated STAT3 maturation. Anticarin-β displays remarkable antitumor efficacy in orthotopic and patient-derived xenograft models of osteosarcoma.Collectively, our data uncover a key role of CCT4 in osteosarcoma, and propose a promising treatment strategy for osteosarcoma by disrupting CCT4 and proteostasis. | Gan Wang Min Zhang Ping Meng Chengbo Long Xiaodong Luo Xingwei Yang Yunfei Wang Zhiye Zhang James Mwangi Peter Muiruri Kamau Zhi Daic Zunfu Ke Yi Zhang Wenlin Chen Xudong Zhao Fei Ge Qiumin Lv Mingqiang Rong Dongsheng Li Yang Jin Xia Sheng Ren Lai | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 1 |
| 5 | Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways显示文摘 | Chengbo Sun Chun Liang Yusheng Ren Yi Zhen Zhiqing He Hua Wang Hongbing Tan Xiaoming Pan Prof. Dr. Zonggui Wu | 2009 | Basic Research in Cardiology2009，，1： | 1 |
| 6 | Modulating the Selectivity of Photocatalytic CO_(2)Reduction in Barium Titanate by Introducing Oxygen Vacancies显示文摘Artifi cial photosynthetic reduction of CO_(2) into valuable chemicals is one of the most promising approaches to solve the energy crisis and decreasing atmospheric CO_(2) emissions.However,the poor selectivity accompanied by the low activity of photocatalysts limits the development of photocatalytic CO_(2) reduction.Herein,inspired by the use of oxygen vacancy engi-neering to promote the adsorption and activation of CO_(2) molecules,we introduced oxygen vacancies in the representative barium titanate(BaTiO 3)photocatalyst for photocatalytic CO_(2) reduction.We found that oxygen vacancies brought signifi cant diff erences in the CO_(2) photoreduction activity and selectivity of BaTiO 3.The intrinsic BaTiO 3 showed a low photocatalytic activity with the dominant product of CO,whereas BaTiO 3 with oxygen vacancies exhibited a tenfold improvement in photocatalytic activity,with a high selectivity of~90%to CH 4.We propose that the presence of oxygen vacancies promotes CO_(2) and H 2 O adsorption onto the BaTiO 3 surface and also improves the separation and transfer of photogenerated carriers,thereby boosting the photocatalytic CO_(2) reduction to CH 4.This work highlights the essential role of oxygen vacancies in tuning the selectivity of photocatalytic reduction of CO_(2) into valuable chemicals. | Yi Wang Chengbo Zhang Rengui Li | 2022 | Transactions of Tianjin University2022，28，4： | 0 |
| 7 | Emergence of highly pathogenic avian influenza A(H5N8)clade 2.3.4.4b viruses in grebes in Inner Mongolia and Ningxia,China,in 2021显示文摘Highly pathogenic avian influenza(HPAI)subtype H5Nx viruses have spread globally and are a major concern for poultry,wild birds,mammals,and even humans(de Vries et al.2015;Zeng et al.2022).The hemagglutinin(HA)genes of H5 subtype viruses have evolved into multiple clades and some of these clades have been further divided into subclades(Cui et al.2022).Clade 2.3.4.4H5N8 HPAI viruses(HPAIVs)have caused several waves of disease outbreaks in wild birds and domestic poultry(Wang et al.2022). | Qiuzi Xu Xinru Lü Yi Li Hua Luo Zhen Zhang Xiang Li Rongxiu Qin Qing An Fengyi Qu Zhenliang Zhao Chengbo Zhang Weidong Wang Yuecheng Li Yajun Wang Xiangwei Zeng Zhijun Hou Jingqiang Ren Yulong Wang Yanbing Li Hongliang Chai | 2024 | Journal of Integrative Agriculture2024，23，1： | 0 |
| 8 | Synaptic transistor with multiple biological functions based on metal-organic frameworks combined with the LIF model of a spiking neural network to recognize temporal information显示文摘Spiking neural networks(SNNs)have immense potential due to their utilization of synaptic plasticity and ability to take advantage of temporal correlation and low power consumption.The leaky integration and firing(LIF)model and spike-timing-dependent plasticity(STDP)are the fundamental components of SNNs.Here,a neural device is first demonstrated by zeolitic imidazolate frameworks(ZIFs)as an essential part of the synaptic transistor to simulate SNNs.Significantly,three kinds of typical functions between neurons,the memory function achieved through the hippocampus,synaptic weight regulation and membrane potential triggered by ion migration,are effectively described through short-term memory/long-term memory(STM/LTM),long-term depression/long-term potentiation(LTD/LTP)and LIF,respectively.Furthermore,the update rule of iteration weight in the backpropagation based on the time interval between presynaptic and postsynaptic pulses is extracted and fitted from the STDP.In addition,the postsynaptic currents of the channel directly connect to the very large scale integration(VLSI)implementation of the LIF mode that can convert high-frequency information into spare pulses based on the threshold of membrane potential.The leaky integrator block,firing/detector block and frequency adaptation block instantaneously release the accumulated voltage to form pulses.Finally,we recode the steadystate visual evoked potentials(SSVEPs)belonging to the electroencephalogram(EEG)with filter characteristics of LIF.SNNs deeply fused by synaptic transistors are designed to recognize the 40 different frequencies of EEG and improve accuracy to 95.1%.This work represents an advanced contribution to brain-like chips and promotes the systematization and diversification of artificial intelligence. | Qinan Wang Chun Zhao Yi Sun Rongxuan Xu Chenran Li Chengbo Wang Wen Liu Jiangmin Gu Yingli Shi Li Yang Xin Tu Hao Gao Zhen Wen | 2023 | Microsystems & Nanoengineering2023，9，4： | 0 |
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