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| 1 | Overexpression of ADAM9 in non-small cell lung cancer correlates with brain metastasis显示文摘The 'a disintegrin and metalloprotease' (ADAM) family contributes to regulation of the cell-cell and cell-matrix interactions that are critical determinants of malignancy. To determine the relationship between metastasis and ADAM proteins, we compared the mRNA levels of ADAM9,-10,-12,-15, and-17 in sublines of an EBC-1 lung cancer cell line that were highly metastatic to either brain or bone. ADAM9 mRNA levels were significantly higher in highly brain-metastatic sublines than in the parent or highly bonemetastalic sublines. To elucidate the role ofADAM9 in brain metastasis, we stably transfected A549 and EBC-1 cells with a fulllength ADAM9 expression vector. Compared with mock-transfectants, ADAM9 overexpression resulted in increased invasive capacity | Shintani Y Higashiyama S Ohta M Hirabayashi H Yamamoto S Yoshimasu T Matsuda H Matsuura N | 2004 | 中国神经肿瘤杂志2004，2，2： | 36 |
| 2 | HRAS突变在具有宽泛形态学谱系的上皮-肌上皮癌中的诊断意义显示文摘上皮-肌上皮癌(EMC)是一种罕见的涎腺肿瘤,组织学上以双相型管状结构为特征,由内层的导管细胞和外层透明的肌上皮细胞组成。由于其组织学的多样性,有时要作出精确诊断极具有挑战性,有用的辅助手段是必不可少的。 | Urano M Nakaguro M Yamamoto Y 魏建国(摘译) 方三高(审校) | 2019 | 临床与实验病理学杂志2019，35，9： | 12 |
| 3 | ^(11)C-methionine (MET) and ^(18)F-fluorothymidine (FLT) PET in patients withnewly diagnosed glioma显示文摘Eur J Nucl Med Mol Imaging. 2008 Jun 10.PURPOSE: The purpose of this prospective study was to clarify the individual and combined role of L: -methyl-(11)C-methionine-positron emission tomography (MET-PET) and 3' -deoxy-3' -[(18)F]fluorothymidine (FLT)-PET in tumor detection,noninvasive grad-ing, and assessment of the cellular proliferation rate in newly diagnosed histologically verified gliomas of different grades. MATERI- | Hatakeyama T Kawai N Nishiyama Y Yamamoto Y Sasakawa Y Ichikawa T Tamiya T | 2008 | 中国神经肿瘤杂志2008，6，2： | 11 |
| 4 | 一种在表面形成Al_2O_3膜的新型耐热奥氏体不锈钢显示文摘一类以在材料表面形成Al2O3膜的奥氏体不锈钢(AFA)的开发正如火如荼地在全球展开。这类合金与传统的、在其表面形成Cr2O3膜的不锈钢相比,在不牺牲其成本、蠕变抗力和可焊性等其它性能的同时具有更高的使用温度和更好的耐环境侵蚀能力。作者简要介绍了该合金的开发方法和其抗氧化和蠕变抗力方面的数据。 | BRADY MP YAMAMOTO Y MAZIASZ PJ SANTELLA ML 韦习成 | 2008 | 自然杂志2008，30，4： | 10 |
| 5 | Carbon catalyzed supercritical water oxidation of phenol 显示文摘 | Matsumura Y Urase T Yamamoto K | 2002 | Journal of Supercritical Fluids2002，22，3： | 2 |
| 6 | A Minimax Rule forPortfolio Selection in Frictional Markets显示文摘 | Wang S Y Yamamoto Y Yu M | 2003 | Mathematical Methods of Operations Research2003，57，： | 2 |
| 7 | Indications for lymph node dissection in the treatment of extrmammary Paget's disease显示文摘 | Tsutaumida A Yamamoto Y Minakawa H | 2003 | Dermatol Surg2003，29，1： | 2 |
| 8 | Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol,independent of body mass index,in the Japanese population显示文摘 | Yamamoto Y Hirose H Saito I | 2002 | Clin Sci (Lond)2002，103，： | 2 |
| 9 | Chemical analysis of surfaces by total-reflection-angle X-ray spectroscopy in rheed experiments (rheed-traxs)显示文摘 | HASEGAWA S YAMAMOTO 1 Y DAIMON H | 1985 | Jpn J Appl Phys1985，24，6： | 2 |
| 10 | COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA显示文摘 | Yamamoto T Sakashita Y | 1998 | Neuroreport1998，9，17： | 2 |
| 11 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 12 | 初产妇和经产妇妊娠期间的诊室和家庭血压显示文摘妊娠高血压可导致分娩时产生严重的并发症,如脑卒中、早产或低出生体质量。初产妇被认为是妊娠高血压的一个危险因素。产次与妊娠期间家庭血压相关性仍不明确。方法:入选初产妇和经产妇共575名,评估妊娠高血压和先兆子痫的发病率。收集在一家日本产科医院接受产前检查的530名正常血压孕妇的家庭和诊室血压值。诊室血压为产前检查2次测量的血压平均值,参与者妊娠期间每日清晨在家自测血压。 | Ishikuro M Obara T Metoki H Ohkubo T Yamamoto M Akutsu K Sakurai K Iwama N Katagiri M Yagihashi K Yaegashi N Mori S Suzuki M Kuriyama S Imai Y 罗冬梅 叶鹏 | 2013 | 中华高血压杂志2013，21，6： | 2 |
| 13 | Hindlimb suspension induces the expression of multiple myosin heavy chain isoforms in single fibres of the rat soleus muscle显示文摘 | Oishi Y Ishihara A Yamamoto H | 1998 | Acta Physiol Scand1998，162，2： | 2 |
| 14 | Hybrid OVSF code assignment scheme in W-CDMA, IEEE Pacific RIM conference on communications 显示文摘 | Sekine Y Kawanishi K Yamamoto U | 2003 | Computers and Signal Processing-Proceedings2003，，1： | 2 |
| 15 | Expression and localization of aquaporins in rat gastrointestinal tract显示文摘 | Koyama Y Yamamoto T Tani T | 1999 | Am physiol cell physiol1999，276，31： | 1 |
| 16 | c-kit and PDGFRA mutations in extragastrointestinal stromal tumor (gastrointestinal stromal tumor of the soft tissue)显示文摘 | Yamamoto H Oda Y Kawaguchi K | 2004 | Am J Surg Pathol2004，28，4： | 1 |
| 17 | Effects of the oxide laver formed on TiN coated silicon wafer on the friction and wear characteristics in dry sliding 显示文摘 | Zhou Y M Asaki R Yamamoto K R | 2003 | Surface and Coatings Technology2003，168，1： | 1 |
| 18 | Expression of vascular endothelial growth factor in human gastric carcinomas显示文摘 | Yasui W Kitadai Y | 1998 | Pathol Int1998，48，7： | 1 |
| 19 | Mucosadhesive DL-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of elcatonin显示文摘 | Yamamoto H Takeuchi H | 2000 | Pharm Dev Technol2000，5，1： | 1 |
| 20 | Xanthophyll cycle enzymes are members of the lipocalin family,the first identified from plants显示文摘 | Hieber A D Yamamoto H Y | 1998 | J Biochem1998，273，15： | 1 |
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