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| 1 | Emerging roles of lactic acid bacteria in protection against colorectal cancer显示文摘Colorectal cancer(CRC)is the third leading cause of cancer deaths worldwide and the fourth most common cancer diagnosed among men and women in the United States.Considering the risk factors of CRC,dietary therapy has become one of the most effective approaches in reducing CRC morbidity and mortality.The use of probiotics is increasing in popularity for both the prevention and treatment of a variety of diseases.As the most common types of microbes used as probiotics,lactic acid bacteria(LAB)are comprised of an ecologically diverse group of microorganisms united by formation of lactic acid as the primary metabolite of sugar metabolism.LAB have been successfully used in managing diarrhea,food allergies,and inflammatory bowel disease.LAB also demonstrated a host of properties in preventing colorectal cancer development by inhibiting initiation or progression through multiple pathways.In this review,we discuss recent insights into cellular and molecular mechanisms of LAB in CRC prevention including apoptosis,antioxidant DNA damages,immune responses,and epigenetics.The emerging experimental findings from clinical trials as well as the proposed mechanisms of gut microbiota in carcinogenesis will also be briefly discussed. | Li Zhong Xufei Zhang Mihai Covasa | 2014 | World Journal of Gastroenterology2014，20，24： | 17 |
| 2 | Enriching short text representation in microblog for clustering显示文摘社会媒介网站允许用户交换短文章例如在友谊网络经由 microblogs 和用户地位鸣叫。他们的有限长度,弥漫的缩写,和制造缩略词和词加重同义和一词多义的问题,并且引起新挑战到象聚类的文本和分类那样的数据采矿应用程序。处理这些问题,我们把一些潜在的原因并且设计由采用机器翻译从不同语言增加特征的数字充实数据表示的一条有效途径。然后,我们建议通过矩阵因式分解技术同时执行多语言知识集成和特征减小的一个新奇框架。建议途径从 Facebook 和 Twitter 在二社会媒介数据集上以有效性广泛地被评估。与它的重要表演改进,我们进一步调查贡献改进表演的潜在的因素。 | Jiliang TANG Xufei WANG Huiji GAO Xia HU Huan LIU | 2012 | Frontiers of Computer Science2012，6，1： | 14 |
| 3 | Development and dynamic characteristics of an Organic Rankine Cycle显示文摘The design, construction and test of an Organic Rankine Cycle(ORC) with R123 as the working fluid were performed. A scroll expander was integrated in the system.The conductive oil with its temperature of 150 °C was used to simulate the low-grade heat source. An AC dynamometer unit measured the expander shaft torque, rotating speed and shaft power. The experiments were conducted in two operating modes: the constant mass flow rate and the constant shaft torque. Under the constant mass flow rate operating mode, the stepped increase of the shaft torque increased the expansion ratios of the expander and decreased the vapor superheats at the expander inlet. Thus,the shaft power and thermal efficiency were increased.Alternatively, the constant shaft torque operating mode involved two different regions, interfaced at the pumping frequency of 9 Hz. By the increase of the mass flow rates,the vapor superheats at the expander inlet was decreased and the shaft power was increased, but the ORC thermal efficiencies were slightly decreased. Both operating modes yielded the saturation shaft powers that were the maximum values one could use. It was found that the measured shaft powers and ORC thermal efficiencies were lower than the enthalpy determined values based on the fluid pressures and temperatures at the expander inlet and outlet. The maximum measured shaft power and thermal efficiency were 2.63 kW and 5.31 %, compared with the enthalpy determined values of 3.87 kW and 9.46 %, respectively. | Zheng Miao Xufei Yang Jinliang Xu Jinghuang Zou | 2014 | Chinese Science Bulletin2014，59，33： | 9 |
| 4 | A novel thermal biosensor based on enzyme reaction for pesticides measurement显示文摘A novel thermal biosensor based on enzyme reaction for pesticides detection has been developed. This biosensor is a flow injection analysis system and consists of two channels with enzyme reaction column and identical reference column, which is set for eliminating the unspecific heat. The enzyme reaction takes place in the enzyme reaction column at a constant temperature(40℃) realized by a thermoelectric thermostat. Thermosensor based on the thermoelectric module containing 127 serial BiTe-thermocouples is used to monitor the temperature difference between two effluents from enzyme reaction column and reference column. The ability of this biosensor to detect pesticides is demonstrated by the decreased degree of the hydrolytic heat in two types of thermosensor mode. The hydrolytic reaction is inhibited by 36% at 1 mg/L DDVP and 50 % at 10 mg/L DDVP when cell-typed thermosensor is used. The percent inhibition is 30% at 1 mg/L DDVP and 42% at 10 mg/L DDVP in tube-typed thermosensor mode. The detection for real sample shows that this biosensor can be used for detection of organophosphate pesticides residue. | ZHENGYi-hua HUATse-chao XUFei | 2005 | Journal of Environmental Sciences2005，17，4： | 7 |
| 5 | Augmented flight dynamics model for pilot workload evaluation in tilt-rotor aircraft optimal landing procedure after one engine failure显示文摘An augmented flight dynamics model is developed to extend the existing flight dynamics model of tilt-rotor aircraft for optimal landing procedure analysis in the event of one engine failure.Compared with the existing flight dynamics model, the augmented model involves with more pilot control information in cockpit and is validated against the flight test data. Based on the augmented flight dynamics model, the optimal landing procedure of XV-15 tilt-rotor aircraft after one engine failure is formulated into a Nonlinear Optimal Control Problem(NOCP), solved by collocation and numerical optimization method. The time histories of pilot controls in cockpit during the optimal landing procedure are obtained for the evaluation of pilot workload. An evaluation method which can synthetically quantify the pilot workload in time and frequency domains is proposed with metrics of aggressiveness and cutoff frequencies of pilot controls. The scale of the pilot workload is compared with those of the shipboard landing procedures, bob-up/bob-down and dash/quickstop maneuvers of UH-60 helicopter. The results show that the aggressiveness of pilot collective and longitudinal controls for the tilt-rotor aircraft optimal landing procedure after one engine failure are higher than those for UH-60 helicopter shipboard landing procedures up to the condition of sea state 4, while the pilot cutoff frequency of collective control is lower than that of the bob-up/bob-down maneuver but the pilot cutoff frequency of longitudinal control is higher than that of the dash/quick-stop maneuver. The evaluated pilot workload level is between Cooper–Harper HQR Level 2 and Level 3. | Xufei YAN Renliang CHEN | 2019 | Chinese Journal of Aeronautics2019，32，1： | 7 |
| 6 | Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis显示文摘嗜曙红血球(曙光女神) 长在层次造血的系统被看作了结束阶段受动器房间。证据的众多的线建议了那个曙光女神是关于各种各样的煽动性或有免疫力的反应的开始,繁殖和规定的多功能的白血球,特别在过敏疾病。最近的研究证明了那个曙光女神也为骨头髓血浆房间的维护和 B 房间的区别被要求。然而,曙光女神是否贡献造血的干细胞(HSC ) 的规定,仍然保持不清楚动态平衡。这里,我们证明曙光女神由在野类型的老鼠损害 HSC 静止和体质能力破坏 HSC 动态平衡后面的 ovalbumin (卵) 挑战并且甚至由引起骨头髓 HSC 在 Cd3-Il-5 转基因的老鼠的失败和疲劳。HSC 的损害维护和功能与导致曙光女神的氧化还原作用不平衡(增加的氧化 phosphorylation 和减少的抗氧化剂层次) 被联系。用集体 spectrometry,更重要地,我们决定 CCL-6 在嗜曙红血球过多下面在高水平被表示。我们证明 CCL-6 为损害 HSC 动态平衡导出曙光女神、负责。有趣地,有特定的抵销抗体的 CCL-6 的阻塞,当在质问卵的老鼠加重嗜曙红血球过多航线发炎时,恢复了 HSC 的体质能力。因此,我们的学习在 HSC 动态平衡揭示 Eos/CCL-6 的意外功能。 | Chao Zhang, Fei Li, Xufei Du, Man Luo, Wen Hua, Wen Li, Zhihua Chen, Songmin Ying, Huahao Shen Weiwei Yi, Hu Wang, Zhenyu Ju Hu Wang, Zhenyu Ju Ping Wu, Chao Peng, Catherine CL Wong James J Lee Songmin Ying Songmin Ying Huahao Shen | 2018 | Cell Research2018，28，3： | 6 |
| 7 | Ambient volatile organic compounds at a receptor site in the Pearl River Delta region:Variations,source apportionment and effects on ozone formation显示文摘We present the continuously measurements of volatile organic compounds(VOCs)at a receptor site(Wan Qing Sha,WQS)in the Pearl River Delta(PRD)region from September to November of 2017.The average mixing ratios of total VOCs(TVOCs)was 36.3±27.9 ppbv with the dominant contribution from alkanes(55.5%),followed by aromatics(33.3%).The diurnal variation of TVOCs showed a strong photochemical consumption during daytime,resulting in the formation of ozone(O_(3)).Five VOC sources were resolved by the positive matrix factorization(PMF)model,including solvent usage(28.6%),liquid petroleum gas(LPG)usage(24.4%),vehicle exhaust(21.0%),industrial emissions(13.2%)and gasoline evaporation(12.9%).The regional transport air masses from the upwind cities of south China can result in the elevated concentrations of TVOCs.Low ratios of TVOCs/NO_(x)(1.53±0.88)suggested that the O_(3) formation regime at WQS site was VOC-limited,which also confirmed by a photochemical box model with the master chemical mechanism(PBM-MCM).Furthermore,the observation on high-O_(3) episode days revealed that frequent O_(3) outbreaks at WQS were mainly caused by the regional transport of anthropogenic VOCs especially for aromatics and the subsequent photochemical reactions.This study provides valuable information for policymakers to propose the effective control strategies on photochemical pollution in a regional perspective. | Yao Meng Junwei Song Lewei Zeng Yingyi Zhang Yan Zhao Xufei Liu Hai Guo Liuju Zhong Yubo Ou Yan Zhou Tao Zhang Dingli Yue Senchao Lai | 2022 | Journal of Environmental Sciences2022，34，1： | 5 |
| 8 | The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR显示文摘On January 22,2020,China National Center for Bioinformation(CNCB)released the 2019 Novel Coronavirus Resource(2019nCoVR),an open-access information resource for the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).2019nCoVR features a comprehensive integration of sequence and clinical information for all publicly available SARS-CoV-2 isolates,which are manually curated with value-added annotations and quality evaluated by an automated in-house pipeline.Of particular note,2019nCoVR offers systematic analyses to generate a dynamic landscape of SARS-CoV-2 genomic variations at a global scale.It provides all identified variants and their detailed statistics for each virus isolate,and congregates the quality score,functional annotation,and population frequency for each variant.Spatiotemporal change for each variant can be visualized and historical viral haplotype network maps for the course of the outbreak are also generated based on all complete and high-quality genomes available.Moreover,2019nCoVR provides a full collection of SARS-CoV-2 relevant literature on the coronavirus disease 2019(COVID-19),including published papers from PubMed as well as preprints from services such as bioRxiv and medRxiv through Europe PMC.Furthermore,by linking with relevant databases in CNCB,2019nCoVR offers data submission services for raw sequence reads and assembled genomes,and data sharing with NCBI.Collectively,SARS-CoV-2 is updated daily to collect the latest information on genome sequences,variants,haplotypes,and literature for a timely reflection,making 2019nCoVR a valuable resource for the global research community.2019nCoVR is accessible at http://gffzzdbc7b6aaae734bddswpbqc0fffoo569vp.ffgz.tsg.suse.edu.cn/ncov/. | Shuhui Song Lina Ma Dong Zou Dongmei Tian Cuiping Li Junwei Zhu Meili Chen Anke Wang Yingke Ma Mengwei Li Xufei Teng Ying Cui Guangya Duan Mochen Zhang Tong Jin Chengmin Shi Zhenglin Du Yadong Zhang Chuandong Liu Rujiao Li Jingyao Zeng Lili Hao Shuai Jiang Hua Chen Dali Han Jingfa Xiao Zhang Zhang Wenming Zhao Yongbiao Xue Yiming Bao | 2020 | Genomics, Proteomics & Bioinformatics2020，18，6： | 4 |
| 9 | Prediction of pilot workload in helicopter landing after one engine failure显示文摘This paper presents a method to predict the pilot workload in helicopter landing after one engine failure.The landing procedure is simulated numerically via applying nonlinear optimal control method in the form of performance index,path constraints and boundary conditions based on an augmented six-degree-of-freedom rigid-body flight dynamics model,solved by collocation and numerical optimization method.UH-60 A helicopter is taken as the sample for the demonstration of landing after one engine failure.The numerical simulation was conducted to find the trajectory of helicopter and the controls from pilot for landing after one engine failure with different performance index considering the factor of pilot workload.The reasonable performance index and corresponding landing trajectory and controls are obtained by making a comparison with those from the flight test data.Furthermore,the pilot workload is evaluated based on wavelet transform analysis of the pilot control activities.The workloads of pilot control activities for collective control,longitudinal and lateral cyclic controls and pedal control during the helicopter landing after one engine failure are examined and compared with those of flight test.The results show that when the performance index considers the factor of pilot workload properly,the characteristics of amplitudes and constituent frequencies of pilot control inputs in the optimal solution are consistent with those of the pilot control inputs in the flight test.Therefore,the proposed method provides a tool of predicting the pilot workload in helicopter landing after one engine failure. | Zhiming YU Xufei YAN Renliang CHEN | 2020 | Chinese Journal of Aeronautics2020，33，12： | 3 |
| 10 | Characteristics and Evaluation of the High-Quality Source Rocks of Cretaceous Continental Shale Oil in Tonghua Basin, China显示文摘The presence of shale oil in the Cretaceous Hengtongshan Formation in the Tonghua Basin, drilled by the well TD-01, has been discussed in this geological investigation for the first time. To evaluate the high-quality source rocks of Cretaceous continental shale oil, the distribution characteristics and the evolution of the ancient environment, samples of shale were systematically analyzed in terms of sedimentary facies, organic geochemistry, and organic carbon isotopic composition. The results demonstrate that a TOC value of 1.5% represents the lower-limit TOC value of the high-quality source rocks. Source rocks have an aggregate thickness of 211 m and contain abundant organic matter, with TOC values of 2.69% on average and a maximum value over 5.44%. The original hydrocarbon-generative potential value(S_1+S_2) is between 0.18 mg/g and 6.13 mg/g, and the Ro is between 0.97% and 1.40%. The thermal maturation of the source rocks is relatively mature to highly mature. The δ^(13)C value range is between -34.75‰ and -26.53‰. The ratio of saturated hydrocarbons to aromatic hydrocarbons is 1.55 to 5.24, with an average of 2.85, which is greater than 1.6. The organic types are mainly type Ⅱ_1, followed by type Ⅰ. The organic carbon source was C_3 plants and hydrophytes. The paleoclimate of the Hengtongshan Formation can be characterized as hot and dry to humid, and these conditions were conducive to the development of high-quality source rocks. A favorable paleoenvironment and abundant organic carbon sources provide a solid hydrocarbon generation base for the formation and accumulation of oil and gas in the shale of the Tonghua Basin. | SHAN Xuanlong DU Shang GUO Xufei | 2019 | Acta Geologica Sinica(English Edition)2019，93，1： | 3 |
| 11 | Trajectory optimization of aerial slung load release for piloted helicopters显示文摘This study aims to provide the pilot with optimal control time histories for stabilization of a helicopter after releasing the slung load in aerial delivery missions. A model with 21 degrees of freedom(21-DOF) has been developed and validated for a helicopter slung load system. The control history is generated with detailed procedure based on trajectory optimization. Effects of the objective function formulation on the results are discussed and rules are obtained to assist in the objective function determination. We conclude that the pilot should first decrease and then increase the collective control and adjust the longitudinal control to stabilize the helicopter after the in-hover slung load release. The obtained control history is reasonable and helpful for safety and efficiency improvement. Effects of path constraints and the Flight Control System(FCS) are studied. More stringent path constraints will lead to longer time spent and more controls. Stronger stiffness and weaker damping from the FCS will cause milder control histories but sharper on-axis state histories. | Luofeng WANG Renliang CHEN Xufei YAN | 2021 | Chinese Journal of Aeronautics2021，34，2： | 3 |
| 12 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016，1，1： | 2 |
| 13 | Pullulan Acetate Coated Magnetite Nanoparticles for Hyper-Thermia:Preparation,Characterization and In Vitro Experiments显示文摘Amphipathic polymer pullulan acetate (PA)-coated magnetic nanoparticles were prepared and characterized by various physicochemical means. The cytotoxicity and cellular uptake of the magnetic nanoparticles were examined. The hyperthermic effect of the magnetic nanoparticles on tumor cells was evaluated. Transmission electron microscopy (TEM) showed that the PA coated magnetic nanoparticles (PAMNs) had spherical morphology. Dynamic light scattering (DLS) showed that the size distribution of PAMNs was unimodal,with an average diameter of 25.8 nm ± 6.1 nm. The presence of the adsorbed layer of PA on the magnetite surface was confirmed by Fourier transform infrared (FTIR) spectroscopy. Magnetic measurements revealed that the saturation magnetization of the PAMNs reached 51.9 emu/g and the nanoparticles were superparamagnetic. Thermogravimetric analysis (TGA) showed that the Fe_(3)O_(4) particles constituted 75 wt% of the PAMNs. The PAMNs had good heating properties in an alternating magnetic field. Cytotoxicity assay showed that PAMNs exhibited no significant cytotoxicity against L929 cells. TEM results showed that a large number of PAMNs were internalized into KB cells. PAMNs have good hyperthermia effect on KB cells in vitro by magnetic field induced hyperthermia. These novel magnetic nanoparticles have great potential as magnetic hyperthermia mediators. | Fuping Gao Yuanyuan Cai Jing Zhou Xiaoxue Xie Weiwei Ouyang Yuhui Zhang Xufei Wang Xiaodong Zhang Xiaowen Wang Lingyun Zhao Jintian Tang | 2010 | Nano Research2010，3，1： | 2 |
| 14 | Taxiing stability verification and airworthiness certification for amphibious aircraft显示文摘Dear editor,Taxiing stability is an important issue in modern civil aircraft development and airworthiness certification.Incidents or abnormal problems consistently arise during aircraft taxiing,as a result of landing gear 'walking',shimmying,and taxiing directional inst ability.The vibrat ions or instability associated with a landing gear system may affect the aircraft’s normal directional control,shorten its service life,and even lead to runway excursion accidents. | Xufei HE Jianliang AI | 2019 | Science China(Information Sciences)2019，62，1： | 2 |
| 15 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 2 |
| 16 | Hyperthermia by a nitinol stent in an alternating magnetic field:Safety and feasibility in rabbit esophageal cancer显示文摘Hyperthermia by heating in-stent is a potentially new method to treat esophageal cancer.This study assessed the safety of heating the rabbit esophagus with a nitinol stent in an alternating magnetic field(AMF) and investigated whether this method offers a therapeutic option for esophageal cancer.Nitinol stents were placed in the cervical esophagi of healthy rabbits,which were heated in an AMF for different times at 43,46 and 50℃.The esophagi were histologically examined after a week to observe whether there was transmural necroses.Then esophageal cancer of rabbit placed nitinol stents were heated in an AMF at 46℃for 10 min.Stents were heated to a target temperature within 5 min.The highest tolerated temperature and time for the healthy rabbit esophagus was at 46℃for 10 min.Tumor growth was delayed by heating and it was statistically significant.Heating the rabbit esophageal wall at 46℃for 10 min proves to be safe and effective in delaying tumor growth. | Jumei Zhou Ning Li Qisheng Xia Lehui Du Xiaowen Wang Linyun Zhao Xufei Wang Jintian Tang | 2009 | Progress in Natural Science:Materials International2009，19，12： | 1 |
| 17 | Community detection via heterogeneous interaction analysis显示文摘 | TANG Lei WANG Xufei LIU Huan | | 0，，1： | 1 |
| 18 | Adsorption equilibrium for Z-ligustilide on C18-bonded silica from supercritical carbon dioxide显示文摘Adsorption equilibrium is of great importance for the preparative supercritical fluid chromatography(pre-SFC) in defining supercritical adsorption behavior and the industrial amplification.This paper presents adsorption isotherms of Z-ligustilide from supercritical carbon dioxide(SC-CO_2) on C18-bonded silica.Adsorption behavior was studied at 305.15 K,313.15 K and 323.15 K with SC-CO_2 density varying from 0.687 g·cm^(-3) to0.863 g·cm^(-3) with the elution by characteristic points(ECP) method.The adsorption amount of Z-ligustilide from SC-CO_2 on C18-bonded silica decreased with the increasing density of the mobile phase as well as the increasing temperature.Adsorption equilibrium data were fitted by Langmuir and Freundlich isotherm models,and the Langmuir isotherm model performed better for describing the whole adsorption process on the column.The monolayer saturation adsorption capacity of Z-ligustilide is in the range of 3.0 × 10^(-4) mg·cm^(-3) to5.5 × 10^(-4) mg·cm^(-3) with an average value of 4.0 × 10^(-4) mg·cm^(-3). | Huisheng Lü Shuangyan Liu Yonghui Li Fanmei Meng Dawei Yao Xufei Mo | 2016 | Chinese Journal of Chemical Engineering2016，24，12： | 1 |
| 19 | Compositional Variability and Mutation Spectra of Monophyletic SARS-CoV-2 Clades显示文摘COVID-19 and its causative pathogen SARS-CoV-2 have rushed the world into a staggering pandemic in a few months,and a global fight against both has been intensifying.Here,we describe an analysis procedure where genome composition and its variables are related,through the genetic code to molecular mechanisms,based on understanding of RNA replication and its feedback loop from mutation to viral proteome sequence fraternity including effective sites on the replicase-transcriptase complex.Our analysis starts with primary sequence information,identity-based phylogeny based on 22,051 SARS-CoV-2 sequences,and evaluation of sequence variation patterns as mutation spectra and its 12 permutations among organized clades.All are tailored to two key mechanisms:strand-biased and function-associated mutations.Our findings are listed as follows:1)The most dominant mutation is C-to-U permutation,whose abundant second-codon-position counts alter amino acid composition toward higher molecular weight and lower hydrophobicity,albeit assumed most slightly deleterious.2)The second abundance group includes three negative-strand mutations(U-to-C,A-to-G,and G-to-A)and a positive-strand mutation(G-to-U)due to DNA repair mechanisms after cellular abasic events.3)A clade-associated biased mutation trend is found attributable to elevated level of negative-sense strand synthesis.4)Within-clade permutation variation is very informative for associating non-synonymous mutations and viral proteome changes.These findings demand a platform where emerging mutations are mapped onto mostly subtle but fast-adjusting viral proteomes and transcriptomes,to provide biological and clinical information after logical convergence for effective pharmaceutical and diagnostic applications.Such actions are in desperate need,especially in the middle of the War against COVID-19. | Xufei Teng Qianpeng Li Zhao Li Yuansheng Zhang Guangyi Niu Jingfa Xiao Jun Yu Zhang Zhang Shuhui Song | 2020 | Genomics, Proteomics & Bioinformatics2020，18，6： | 1 |
| 20 | The application of proton spectrometers at the SG-III facility for ICF implosion areal density diagnostics显示文摘Charged particle diagnostics is one of the required techniques for implosion areal density diagnostics at the SG-III facility.Several proton spectrometers are under development, and some preliminary areal density diagnostics have been carried out. The response of the key detector, CR39, to charged particles was investigated in detail. A new track profile simulation code based on a semi-empirical model was developed. The energy response of the CR39 detector was calibrated with the accelerator protons and alphas from a241 Am source. A proton spectrometer based on the filtered CR39 detector was developed, and D–D primary proton measurements were implemented. A step range filter spectrometer was developed,and preliminary areal density diagnostics was carried out. A wedged range filter spectrometer array made of Si with a higher resolution was designed and developed at the SG-III facility. A particle response simulation code by the Monte Carlo method and a spectra unfolding code were developed. The capability was evaluated in detail by simulations. | Xing Zhang Jianhua Zheng Ji Yan Zhenghua Yang Ming Su Yudong Pu Pin Yang Xufei Xie Li Chen Ming Chen Tianxuan Huang Shao'en Jiang Shenye Liu Jiamin Yang | 2015 | High Power Laser Science and Engineering2015，3，4： | 1 |
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