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234篇 您的检索式:作者名="Yuhui Zhang"
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1Summer atmospheric boundary layer structure in the hinterland of Taklimakan Desert, China显示文摘Understanding the characteristics of the structure of desert atmospheric boundary layer and its land surface process is of great importance to the simulations of regional weather and climate.To investigate the atmospheric boundary layer structure and its forming mechanism of Taklimakan Desert,and to improve the accuracy and precision of regional weather and climate simulations,we carried out a GPS radiosonde observation experiment in the hinterland of Taklimakan Desert from 25 June to 3 July,2015.Utilizing the densely observed sounding data,we analyzed the vertical structures of daytime convective boundary layer and nighttime stable boundary layer in summer over this region,and also discussed the impacts of sand-dust and precipitation events on the desert atmospheric boundary layer structure.In summer,the convective boundary layer in the hinterland of Taklimakan Desert developed profoundly and its maximum height could achieve 4,000 m;the stable boundary layer at nighttime was about 400–800-m thick and the residual mixing layer above it could achieve a thickness over 3,000 m.Sand-dust weather would damage the structures of nighttime stable boundary layer and daytime convective boundary layer,and the dust particle swarm can weak the solar radiation absorbed by the ground surface and further restrain the strong development of convective boundary layer in the daytime.Severe convective precipitation process can change the heat from the ground surface to the atmosphere in a very short time,and similarly can damage the structure of desert atmospheric boundary layer remarkably.Moreover,the height of atmospheric boundary layer was very low when raining.Our study verified the phenomenon that the atmospheric boundary layer with supernormal thickness exists over Taklimakan Desert in summer,which could provide a reference and scientific bases for the regional numerical models to better represent the desert atmospheric boundary layer structure.WANG Minzhong WEI Wenshou HE Qing YANG Yuhui FAN Lei ZHANG Jiantao 2016Journal of Arid Land2016,8,6:17
2Unified representation of formulas for single birth processes显示文摘Mu-Fa CHEN Yuhui ZHANG 2014Frontiers of Mathematics in China2014,9,4:13
3Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12显示文摘Increasing evidences show that aberrant subchondral bone remodeling plays an important role in the development of osteoarthritis(OA).However,how subchondral bone formation is activated and the mechanism by which increased subchondral bone turnover promotes cartilage degeneration during OA remains unclear.Here,we show that the mechanistic target of rapamycin complex 1(mTORC1)pathway is activated in subchondral bone preosteoblasts(Osterix+)from OA patients and mice.Constitutive activation of mTORC1 in preosteoblasts by deletion of the mTORC1 upstream inhibitor,tuberous sclerosis 1,induced aberrant subchondral bone formation,and sclerosis with little-to-no effects on articular cartilage integrity,but accelerated posttraumatic OA development in mice.In contrast,inhibition of mTORC1 in preosteoblasts by disruption of Raptor(mTORC1-specific component)reduced subchondral bone formation and cartilage degeneration,and attenuated post-traumatic OA in mice.Mechanistically,mTORC1 activation promoted preosteoblast expansion and Cxcl12 secretion,which induced subchondral bone remodeling and cartilage degeneration during OA.A Cxcl12-neutralizing antibody reduced cartilage degeneration and alleviated OA in mice.Altogether,these findings demonstrate that mTORC1 activation in subchondral preosteoblasts is not sufficient to induce OA,but can induce aberrant subchondral bone formation and secrete of Cxcl12 to accelerate disease progression following surgical destabilization of the joint.Pharmaceutical inhibition of the pathway presents a promising therapeutic approach for OA treatment.Chuangxin Lin Liangliang Liu Chun Zeng Zhong-Kai Cui Yuhui Chen Pinling Lai Hong Wang Yan Shao Haiyan Zhang Rongkai Zhang Chang Zhao Hang Fang Daozhang Cai Xiaochun Bai 2019Bone Research2019,7,1:12
4The Algorithm of Infeasible Paths Extraction Oriented the Function Calling Relationship显示文摘MU Yongmin ZHENG Yuhui ZHANG Zhihua LIU Mengting 2012Chinese Journal of Electronics2012,21,2:12
5Space-Air-Ground Integrated Network (SAGIN) for 6G: Requirements, Architecture and Challenges显示文摘As the fifth-generation(5G)mobile communication network may not meet the requirements of emerging technologies and applications,including ubiquitous coverage,industrial internet of things(IIoT),ubiquitous artificial intelligence(AI),digital twins(DT),etc.,this paper aims to explore a novel space-air-ground integrated network(SAGIN)architecture to support these new requirements for the sixth-generation(6G)mobile communication network in a flexible,low-latency and efficient manner.Specifically,we first review the evolution of the mobile communication network,followed by the application and technology requirements of 6G.Then the current 5G non-terrestrial network(NTN)architecture in supporting the new requirements is deeply analyzed.After that,we proposes a new flexible,low-latency and flat SAGIN architecture,and presents corresponding use cases.Finally,the future research directions are discussed.Huanxi Cui Jun Zhang Yuhui Geng Zhenyu Xiao Tao Sun Ning Zhang Jiajia Liu Qihui Wu Xianbin Cao 2022China Communications2022,19,2:11
6Effect of Tiaoshen Kaiqiao acupuncture in the treatment of ischemic post-stroke depression:a randomized controlled trial显示文摘OBJECTIVE:To observe the effect of Tiaoshen Kaiqiao acupuncture in the treatment of ischemic post-stroke depression.METHODS:This research was a single-blind, positive-controlled trial done in a single entity.Totally58 patients with ischemic post-stroke depression were randomly divided into two groups.The acupuncture group was given Tiaoshen Kaiqiao acupuncture therapy and placebo starch tablets treatment,while the control group was treated with fluoxetine tablets and body acupuncture treatment.Evaluated the clinical efficacy of the two groups with Hamilton Depression Scale(HAMD),Anti Depression Drug Side Effects Rating Scale(SERS), Clinical Global Impression Scale(CGI) respectively before treatment, the fourth weekend of treatment, the eighth weekend of treatment,the twelfth weekend of treatment.The adverse reactions in two groups were observed and documented.RESULTS:The HAMD scale scores of the two groups in different treatment period were significantly decreased compared with that before treatment(P < 0.05); the score reduction of HAMD scale between the two groups had no significant differences(P > 0.05).There was significant difference between the SERS scores of two groups(P < 0.05); the control group had more adverse reactions, and the score would be increased with the extension of treatment time.Effect index(EI) of CGI in the acupuncture group is better than that of control group(P < 0.05).CONCLUSION:The effects of Tiaoshen Kaiqiao acupuncture and fluoxetine in the treatment of ischemic post-stroke depression were similar, but the former had no obvious adverse reaction and side effects.Li Menghan Zhang Bo Meng Zhihong Sha Tao Han Yuhui Zhao Hong Zhang Chunhong 2017Journal of Traditional Chinese Medicine2017,37,2:10
7Performance of sulfate-dependent anaerobic ammonium oxidation显示文摘The performance of sulfate-dependent anaerobic ammonium oxidation was studied.The results showed that both SO42-and NH4+ were chemically stable under anaerobic conditions.They did not react with each other in the absence of biological catalyst(sludge).The anaerobic digested sludge cultivated in an anaerobic reactor for three years took on the ability of oxidizing ammonium with sulfate anaero-bically.The average reduction of sulfate and ammonium was 71.67 mg.L-1 and 56.82 mg.L-1 at high concentrations.The reaction between SO42-and NH4+ was difficult,though feasible,due to its low standard Gibbs free energy change.The experiment demonstrated that high substrate concentrations and low oxidation-reduction potential(ORP) may be favourable for the biological reaction.ZHANG Lei ZHENG Ping HE YuHui JIN RenCun 2009Science China Chemistry2009,52,1:9
8Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome:a 15-year follow-up from a prospective cohort study显示文摘The most severe sequelae after rehabilitation from SARS are femoral head necrosis and pulmonary fibrosis. We performed a 15-year follow-up on the lung and bone conditions of SARS patients. We evaluated the recovery from lung damage and femoral head necrosis in an observational cohort study of SARS patients using pulmonary CT scans, hip joint MRI examinations, pulmonary function tests and hip joint function questionnaires. Eighty medical staff contracted SARS in 2003. Two patients died of SARS, and78 were enrolled in this study from August 2003 to March 2018. Seventy-one patients completed the 15-year follow-up. The percentage of pulmonary lesions on CT scans diminished from 2003(9.40 ± 7.83)% to 2004(3.20 ± 4.78)%(P < 0.001) and remained stable thereafter until 2018(4.60 ± 6.37)%. Between 2006 and 2018, the proportion of patients with interstitial changes who had improved pulmonary function was lower than that of patients without lesions, as demonstrated by the one-second ratio(FEV1/FVC%, t = 2.21, P = 0.04) and mid-flow of maximum expiration(FEF25%–75%, t = 2.76, P = 0.01). The volume of femoral head necrosis decreased significantly from 2003(38.83 ± 21.01)% to 2005(30.38 ± 20.23)%(P = 0.000 2), then declined slowly from 2005 to 2013(28.99 ± 20.59)% and plateaued until 2018(25.52 ± 15.51)%. Pulmonary interstitial damage and functional decline caused by SARS mostly recovered, with a greater extent of recovery within 2 years after rehabilitation. Femoral head necrosis induced by large doses of steroid pulse therapy in SARS patients was not progressive and was partially reversible.Peixun Zhang Jia Li Huixin Liu Na Han Jiabao Ju Yuhui Kou Lei Chen Mengxi Jiang Feng Pan Yali Zheng Zhancheng Gao Baoguo Jiang 2020Bone Research2020,8,1:8
9Effects of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos显示文摘In recent years,with the wide applications and mineral exploitation of rare earth elements,their potential environmental and health effects have caused increasing public concern.Effect of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos were studied.The embryos were exposed to La3+ or Yb3+ at 0,0.01,0.1,0.3,0.5 and 1.0 mmol/L,respectively.Early life stage parameters such as egg and embryo mortality,gastrula development,tail detachment,eyes,somite formation,circulatory system,pigmentation,malformations,hatching rate,length of larvae and mortality were investigated.The results showed La3+ and Yb3+ delayed zebrafish embryo and larval development,decreased survival and hatching rates,and caused tail malformation in a concentration-dependent way.Moreover,heavy rare-earth ytterbium led to more severe acute toxicity of zebrafish embryo than light rare-earth lanthanum.Jun'an Cui Zhiyong Zhang Wei Bai Ligang Zhang Xiao He Yuhui Ma Yan Liu Zhifang Chai 2012Journal of Environmental Sciences2012,24,2:8
10Carbon-supported Fe/Co-N electrocatalysts synthesized through heat treatment of Fe/Co-doped polypyrrole-polyaniline composites for oxygen reduction reaction显示文摘In this paper,we synthesized cathode catalysts(PANI-PPYR,Fe/PANI-PPYR,Co/PANI-PPYR and Fe-Co/PANI-PPYR)with high performance oxygen reduction by using a simple heat treatment process.These catalysts were fabricated by directly calcining the Fe and/or Co doped polyaniline(PANI)-polypyrrole(PPYR)composites.Their electrocatalytic activity for ORR both in acidic and in alkaline media was investigated by voltammetric techniques.Among the prepared catalysts,Co/PANI-PPYR presents the most positive ORR onset potential of 0.62 V(vs.SCE)in 0.5 mol/L H2SO4 solution or?0.09 V(vs.SCE)in 1 mol/L NaOH solution.In addition,the Co/PANI-PPYR catalyst shows the largest limiting-diffusion current density for ORR,which is 4.3 mA/cm2@0.2 V(vs.SCE)in acidic and 2.3 mA/cm2@?0.3 V(vs.SCE)in alkaline media.In acidic media,a four-electron reaction of ORR on the Co/PANI-PPYR and Fe/PANI-PPYR catalysts is more dominant than a two-electron reaction.In alkaline media,however,a four-electron and a two-electron mechanisms are co-present for the ORR on all the prepared catalysts.Co/PANI-PPYR catalyst also presents good electrocatalytic activity stability for ORR both in acidic and in alkaline media.YI QingFeng ZHANG YuHui LIU XiaoPing YANG YaHui 2014Science China Chemistry2014,57,5:8
11Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis:a randomized,double-blind,placebo-controlled phase 2 trial显示文摘Rheumatoid arthritis(RA)is an aggressive autoimmune arthritis,and current therapies remain unsatisfactory due to low remission rate and substantially adverse effects.Low-dose interleukin-2(Ld-IL2)is potentially a therapeutic approach to further improve the disease.This randomized,double-blind,placebo-controlled trial was undertaken to evaluate the efficacy and safety of Ld-IL2 in patients with active RA.Patients were randomly assigned(1:1)to receive Ld-IL2,defined as a dose of 1 million IU,or placebo in a 12-week trial with a 12-week follow-up.Three cycles of Ld-IL2 or placebo were administered subcutaneously every other day for 2 weeks(a total of 7 doses),followed by a 2-week break.All patients received a stable dose of methotrexate(MTX).The primary outcomes were the proportion of patients achieving the ACR20,DAS28-ESR<2.6,and the change from baseline in CDAI or SDAI at week 24.Secondary endpoints included other clinical responses and safety.The primary outcomes were achieved in the perprotocol population.The improvements from baseline in CDAI and SDAI were significantly greater across time points for the LdIL2+MTX group(n=17)than for the placebo+MTX group(n=23)(P=0.018 and P=0.015,respectively).More patients achieved ACR20 response in the Ld-IL2+MTX group than those in the placebo+MTX group at week 12(70.6%vs 43.5%)and at week 24(76.5%vs 56.5%)(P=0.014).In addition,low Treg and high IL-21 were associated with good responses to Ld-IL2.Ld-IL-2 treatment was well-tolerated in this study.These results suggested that Ld-IL2 was effective and safe in RA.ClinicalTrials.gov number:NCT 02467504.Xiaoying Zhang Miao Miao Ruijun Zhang Xu Liu Xiaozhen Zhao Miao Shao Tian Liu Yuebo Jin Jiali Chen Huixin Liu Xia Zhang Yun Li Yunshan Zhou Yue Yang Ru Li Haihong Yao Yanying Liu Chun Li Yuhui Li Limin Ren Yin Su Xiaolin Sun Jing He Zhanguo Li 2022Signal Transduction and Targeted Therapy2022,7,4:7
12Sufficient and Necessary Conditions for Stochastic Comparability of Jump ProcessesYuhui Zhang Department of Mathematics,Beijing Normal University,Beijing 100875,P.R.China 2000Acta Mathematica Sinica,English Series2000,16,1:7
13Criteria on ergodicity and strong ergodicity of single death processes显示文摘Yuhui ZHANG 2018Frontiers of Mathematics in China2018,13,5:7
14Perovskite light-emitting/detecting bifunctional fibres for wearable LiFi communication显示文摘Light fidelity(LiFi),which is emerging as a compelling technology paradigm shifting the common means of highcapacity wireless communication technologies,requires wearable and full-duplex compact design because of its great significance in smart wearables as well as the‘Internet of Things’.However,the construction of the key component of wearable full-duplex LiFi,light-emitting/detecting bifunctional fibres,is still challenging because of the conflicting process between carrier separation and recombination,as well as the highly dynamic film-forming process.Here,we demonstrate light-emitting/detecting bifunctional fibres enabled by perovskite QDs with hybrid components.The hybrid perovskite inks endow fibres with super-smooth QD films.This,combined with the small exciton binding energy and high carrier mobility of perovskite QDs,enables successful integration of electroluminescence and photodetection into monofilaments.The bifunctional fibres possess the narrowest electroluminescence full width at half maximum of ~19 nm and,more importantly,the capability for simultaneously transmitting and receiving information.The successful fabrication of narrow emission full-duplex LiFi fibres paves the way for the fabrication and integration of low crosstalk interoperable smart wearables.Qingsong Shan Changting Wei Yan Jiang Jizhong Song Yousheng Zou Leimeng Xu Tao Fang Tiantian Wang Yuhui Dong Jiaxin Liu Boning Han Fengjuan Zhang Jiawei Chen Yongjin Wang Haibo Zeng 2020Light(Science & Applications)2020,9,1:7
15Micro RNA profiles and potential regulatory pattern during the early stage of spermatogenesis in mice显示文摘Spermatogenesis is a complicated and poorly understood process that relies on the precise regulation of the self-renewal and differentiation of spermatogonia. In many organisms, micro RNAs(mi RNAs) are involved in multiple developmental processes as critical regulators of transcriptional and post-transcriptional gene silencing. This study investigated the expression pattern of mi RNAs in type B spermatogonia cells(BSc) and primary spermatocytes(PSc) of mice, using a high-throughput small RNA sequencing system. The results revealed that the expression levels of Let-7 family mi RNAs were remarkably high in both cell types. Furthermore, the expression levels of mi R-21, mi R-140-3p, mi R-103, mi R-30 a, mi R-101 b and mi R-99 b were decreased during the transformation from BSc to PSc. These mi RNAs target vital genes that participate in apoptosis, cell proliferation and differentiation, junction assembly and cell cycle regulation. These results highlight the indispensable role of mi RNAs in spermatogenesis.LUO MengMeng HAO LiLi HU Fen DONG YaNan GOU LiXia ZHANG WenDian WANG Xin ZHAO YuHui JIA MengChun HU SongNian ZHANG XiuJun 2015Science China(Life Sciences)2015,58,5:6
16Overview of deep space laser communication显示文摘The deep space probe is a vital technology for observing and exploring the universe. It is thus intensifying as an aerospace research focus on an international scale. Despite improving the frequency band,the conventional microwave communication technique has difficulty satisfying the increased demand for the enormous volume of scientific data returning to the Earth. With a carrier frequency that is several orders of magnitude higher than the microwave, free-space optical communication is a robust and promising method for achieving both high bit rates and long distances in deep space communication. In this article, the history of this technology is summarized and the objective laws are formulated, while key techniques and development trends are analyzed. Finally, useful concepts and suggestions are proposed for the development of deep space laser communication in China.Weiren WU Ming CHEN Zhe ZHANG Xiangnan LIU Yuhui DONG 2018Science China(Information Sciences)2018,61,4:6
17PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus显示文摘地岬在许多细胞的活动起一个枢轴的作用,并且它的 subcellular 区分提供空间、时间的选择。这里,我们报导由二高度相应的蛋白质 PAQR10 和孕激素和 AdipoQ 受体家庭的 PAQR11 在 Golgi 仪器发信号的地岬的空间规定的一个模式。PAQR10 和 PAQR11 在 Golgi 仪器是只局部性的。PAQR10/PAQR11 的 Overexpression 刺激基础、导致 EGF 的英皇家空军之阶级最低之兵 phosphorylation 并且以一种剂量依赖者方式增加英皇家空军之阶级最低之兵目标基因的表示。PAQR10/PAQR11 的 Overexpression 显著地提高 HRas, NRas 和 KRas4A 的 Golgi 本地化,然而并非 KRas4B。PAQR10 和 PAQR11 罐头也与 HRas, NRas 和 KRas4A 交往,然而并非 KRas4B。在由 PAQR10/PAQR11 的 overexpression 的 Golgi 仪器的增加的地岬蛋白质处于一个活跃状态。一致地, PAQR10 和 PAQR11 还原剂击倒在 Golgi 仪器的刺激 EGF 的英皇家空军之阶级最低之兵 phosphorylation 和地岬激活。有趣地, PAQR10 和 PAQR11 能与 RasGRP1,地岬的 guanine 核苷酸交换蛋白质,和 RasGRP1 的增加 Golgi 本地化交往。RasGRP1 的 C1 领域为和 PAQR10/PAQR11 的 RasGRP1 的相互作用必要、足够。由 overexpressed PAQR10/PAQR11 的英皇家空军之阶级最低之兵 phosphorylation 的模拟被 RasGRP1 的 downregulation 废除。而且, PC12 房间的区别被 PAQR10/PAQR11 的 overexpression 显著地提高。一起,这研究揭开由 PAQR10 和 PAQR11 在 Golgi 仪器发信号的地岬的空间规定的一个新范例。Ting Jin Qiurong Ding Heng Huang Daqian Xu Yuhui Jiang Ben Zhou Zhenghu Li Xiaomeng Jiang Jing He Weizhong Liu Yixuan Zhang Yi Pan Zhenzhen Wang Walter G Thomas Yan Chen 2012Cell Research2012,22,4:6
18Composition optimized trimetallic PtNiRu dendritic nanostructures as I versatile and active electrocatalysts for alcohol oxidation显示文摘Platinum-based nano crystals are the most effective electrocatalysts for accelerati ng the chemical tran sformatio ns on the anode in direct alcohol fuel cells. To facilitate practical applications and overcome the drawbacks of diverse alcohols, it is significant to develop electrocatalysts with high activities and a wide fuel flexibility. Here, we demonstrate a practicable solution method for fabricating composition tun able trimetallic PtNiRu den dritic nano structures (DNSs) which can serve as versatile and active catalysts for electrooxidatio n of a variety of liquid alcohols. A series of trimetallic DNSs with tun able Pt/Ni/Ru atomic ratios were successfully syn thesized by simply adjusti ng the feeding of precursors. Detailed electrochemical test indicates that, among other compositions, the Pt66Ni27Ru7 DNSs present much superior electroactivity in catalyzing electrooxidation of liquid alcohols in acidic mediums. Specifically, the mass activity and specific activity on the Pt66Ni27Ru7 DNSs, for electrooxidation of methanol, ethanol, and ethylene glycol, are 4.57 and 4.34 times, 3.55 and 3.42 times, and 2.37 and 2.28 times that of the commercial Pt black, respectively. X-ray photoelectron spectroscopy and CO stripping studies reveal the adsorption of CO on these PtNiRu DNSs is much weaker than on pure Pt. Meanwhile, the surface Ru sites can provide neighbouring -OH groups to facilitate the oxidati on and removal of the adsorbed in termediates (-CO) on the surface Pt sites, effectively improvi ng the CO tolera nee of the catalysts. The PtNiRu DNSs also show effectively boosted capacity for breaking the C-C bond in C2-alcohols, showing great potential for fuel-flexible fuel cell applications.Yan Lu Wei Wang Xiaowei Chen Yuhui Zhang Yanchen Han Yong Cheng Xue-Jiao Chen Kai Liu Yuanyuan Wang Qiaobao Zhang Shuifen Xie 2019Nano Research2019,12,3:6
19Distributed learning particle swarm optimizer for global optimization of multimodal problems显示文摘Geng ZHANG Yangmin LI Yuhui SHI 2018Frontiers of Computer Science2018,12,1:5
20High-density genetic map construction and identification of loci controlling flower-type traits in Chrysanthemum(Chrysanthemum×morifolium Ramat.)显示文摘Flower type is an important and extremely complicated trait of chrysanthemum.The corolla tube merged degree(CTMD)and the relative number of ray florets(RNRF)are the two key factors affecting chrysanthemum flower type.However,few reports have clarified the inheritance of these two complex traits,which limits directed breeding for flower-type improvement.In this study,305 F1 hybrids were obtained from two parents with obvious differences in CTMD and RNRF performance.Using specific-locus amplified fragment sequencing(SLAF-seq)technology,we constructed a high-density genetic linkage map with an average map distance of 0.76 cM.Three major QTLs controlling CTMD and four major QTLs underlying RNRF were repeatedly detected in the 2 years.Moreover,the synteny between the genetic map and other Compositae species was investigated,and weak collinearity was observed.In QTL regions with a high degree of genomic collinearity,eight annotated genes were probed in the Helianthus annuus L.and Lactuca sativa L.var.ramosa Hort.genomes.Furthermore,20 and 11 unigenes were identified via BLAST searches between the SNP markers of the QTL regions and the C.vestitum and C.lavandulifolium transcriptomes,respectively.These results lay a foundation for molecular marker-assisted breeding and candidate gene exploration in chrysanthemum without a reference assembly.Xuebin Song Yuhui Xu Kang Gao Guangxun Fan Fan Zhang Chengyan Deng Silan Dai He Huang Huaigen Xin Yingying Li 2020Horticulture Research2020,7,1:5
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