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| 1 | Cloning and functional characterization of Rht8,a“Green Revolution”replacement gene in wheat显示文摘Dear Editor,Wheat(Triticum aestivum)is a major staple crop in the world and provides~20%of the food calories for human consumption(Appels et al.,2018).During the 1960s and 1970s,the introduction of two semi-dwarfing genes Rht-B1b and Rht-D1b in wheat varieties strikingly improved lodging resistance and harvest index,and therefore substantially increased grain yield,resulting in the well-known'Green Revolution'(Peng et al.,1999).However,plants carrying Rht-B1b and Rht-D1b suffer from several drawbacks. | Hongchun Xiong Chunyun Zhou Meiyu Fu Huijun Guo Yongdun Xie Linshu Zhao Jiayu Gu Shirong Zhao Yuping Ding Yuting Li Jiazi Zhang Ke Wang Xuejun Li Luxiang Liu | 2022 | Molecular Plant2022，15，3： | 7 |
| 2 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 3 | Characterization of particulate products for aging of ethylbenzene secondary organic aerosol in the presence of ammonium sulfate seed aerosol显示文摘Aging of secondary organic aerosol(SOA) particles formed from OH– initiated oxidation of ethylbenzene in the presence of high mass(100–300 μg/m^3) concentrations of(NH_4)_2SO_4seed aerosol was investigated in a home-made smog chamber in this study.The chemical composition of aged ethylbenzene SOA particles was measured using an aerosol laser time-of-flight mass spectrometer(ALTOFMS) coupled with a Fuzzy C-Means(FCM) clustering algorithm.Experimental results showed that nitrophenol,ethyl-nitrophenol,2,4-dinitrophenol,methyl glyoxylic acid,5-ethyl-6-oxo-2,4-hexadienoic acid,2-ethyl-2,4-hexadiendioic acid,2,3-dihydroxy-5-ethyl-6-oxo-4-hexenoic acid,1H-imidazole,hydrated N-glyoxal substituted1H-imidazole,hydrated glyoxal dimer substituted imidazole,1H-imidazole-2-carbaldehyde,N-glyoxal substituted hydrated 1H-imidazole-2-carbaldehyde and high-molecular-weight(HMW) components were the predominant products in the aged particles.Compared to the previous aromatic SOA aging studies,imidazole compounds,which can absorb solar radiation effectively,were newly detected in aged ethylbenzene SOA in the presence of high concentrations of(NH_4)_2SO_4seed aerosol.These findings provide new information for discussing aromatic SOA aging mechanisms. | Mingqiang Huang Jiahui Zhang Shunyou Cai Yingmin Liao Weixiong Zhao Changjin Hu Xuejun Gu Li Fang Weijun Zhang | 2016 | Journal of Environmental Sciences2016，28，9： | 6 |
| 4 | Revisiting the Concentration Observations and Source Apportionment of Atmospheric Ammonia显示文摘While China’s Air Pollution Prevention and Control Action Plan on particulate matter since 2013 has reduced sulfate significantly,aerosol ammonium nitrate remains high in East China.As the high nitrate abundances are strongly linked with ammonia,reducing ammonia emissions is becoming increasingly important to improve the air quality of China.Although satellite data provide evidence of substantial increases in atmospheric ammonia concentrations over major agricultural regions,long-term surface observation of ammonia concentrations are sparse.In addition,there is still no consensus on whether agricultural or non-agricultural emissions dominate the urban ammonia budget.Identifying the ammonia source by nitrogen isotope helps in designing a mitigation strategy for policymakers,but existing methods have not been well validated.Revisiting the concentration measurements and identifying source apportionment of atmospheric ammonia is thus an essential step towards reducing ammonia emissions. | Yuepeng PAN Mengna GU Yuexin HE Dianming WU Chunyan LIU Linlin SONG Shili TIAN Xuemei LÜ Yang SUN Tao SONG Wendell WWALTERS Xuejun LIU Nicholas AMARTIN Qianqian ZHANG Yunting FANG Valerio FERRACCI Yuesi WANG | 2020 | Advances in Atmospheric Sciences2020，37，9： | 4 |
| 5 | Efficacy of miacalcic in treating a hypercalcemia crisis caused by Williams-Beuren syndrome显示文摘Williams-Beuren syndrome (WBS) is a hereditary disease involving multiple systems due to microdeletion of chromosome 7q11.23.The deleted region in most patients is approximately 1.55 Mb,including 26-28 genes.The incidence of WBS in live-born children is roughly 1/7 500-1/25 000.1 The majority of WBS cases are sporadic;inheritance is autosomal dominant.The clinical manifestations of WBS include aortic valve stenosis alone or combined with other cardiovascular malformations,characteristic facies (full peri-orbital region,flat and short nose,upward pointingnose,long philtrum,wide mouth thick lips,and disorders of the teeth),temporary hypercalcemia,developmental retardation associated with mild-to-moderate dysgnosia,and personality changes.Salmon calcitonin (miacalcic) is widely used in the treatment of adult hypercalcemia crisis. | Gu Yi Gong Chunxiu Shen Ying Wu Di Liang Xuejun Chang Bo Liu Ying Wang Yi | 2014 | Chinese Medical Journal2014，，13： | 4 |
| 6 | A Streptococcus suis serotype 2 caused streptococcal toxic shock syndrome(STSS) in a patient显示文摘Streptococcus suis(S.suis)is a Gram-positive,facultatively anaerobic coccus that has been implicated as the cause of a wide range of clinical disease syndromes in swine and other domestic animals.S.suis has also been implicated in disease in humans,especially among abattoir workers,swine and pork handlers.Here we report a case of streptococcal toxic shock syndrome(STSS)caused by S.suis in a 59-year-old man.Despite of intensive treatment,the patient died of shock with multiple organ failure 14 h after admission.One bacterial isolate obtained from blood culture was identified to the species level by biochemical tests and serological tests as S.suis serotype 2.Identification was confirmed by PCR amplification of genes encoding 16sRNA of S.suis and the capsule of S.suis serotype 2(cps 2J).Genes encoding virulence factors were also detected.An investigation to identify the source of S.suis revealed that several days before admission the affected man had been handling sick pigs or their meat.Transmission may occur through breaks in the skin of feet with tinea due to that no measures for personal protection was taken.This case should highten awareness of the potential for occupational exposure and human infection with S.suis. | Yefei Zhu Zhongmin Tan Lingyang Zhu Hongxing Pan Xuejun Zhang Lei Xu Huimin Qian Ling Gu Xun Ye Chen Dong Changjun Bao Rongqiang Zhu Fengcai Zhu Hua Wang | 2008 | Journal of Nanjing Medical University2008，22，5： | 3 |
| 7 | Size distribution and chemical composition of secondary organic aerosol formed from Cl-initiated oxidation of toluene显示文摘Secondary organic aerosol (SOA) formed from Cl-initiated oxidation of toluene was investigated in a home-made smog chamber. The size distribution and chemical composition of SOA particles were measured using aerodynamic particle sizer spectrometer and the aerosol laser time-of-flight mass spectrometer (ALTOFMS), respectively. According to a large number of single aerosol diameter and mass spectra, the size distribution and chemical composition of SOA were obtained statistically. Experimental results showed that SOA particles created by Cl-initiated oxidation of toluene is predominantly in the form of fine particles, which have diameters less than 2.5 μm (i.e., PM2.5), and glyoxal, benzaldehyde, benzyl alcohol, benzoquinone, benzoic acid, benzyl hydroperoxide and benzyl methyl nitrate are the major products components in the SOA. The possible reaction mechanisms leading to these products are also proposed. | Mingqiang Huang Weijun Zhang Xuejun Gu Changjin Hu Weixiong Zhao Zhenya Wang Li Fang | 2012 | Journal of Environmental Sciences2012，24，5： | 3 |
| 8 | Clinical features and predictors of remission in children under the age of 7 years with Graves’disease显示文摘Importance:Graves’disease(GD)is rare in children under the age of 7 years.Children with this disease exhibit greater thyrotoxicity at diagnosis and require a longer course of medical therapy,compared with pubertal and postpubertal children and adults.Objective:To investigate the clinical features and identify predictors of remission in children under the age of 7 years with GD.Methods:This retrospective study included 77 children who were diagnosed with GD under the age of 7 years and were treated in the Department of Endocrinology,Beijing Children’s Hospital from 2010 to 2018.Clinical manifestations,laboratory data,and follow-up records were collected for all patients.Children who achieved remission of treatment with methimazole were compared with those who had persistent disease to identify which variables were associated with remission;multiple logistic regression and Cox regression analyses were used to evaluate interactions among predictive variables.Results:Sixty-three boys and 14 girls were included;the median age at diagnosis was 4.2 years(interquartile range:3.2-5.3 years).Forty-six(56.7%)patients had no family history of thyroid disease,17 patients had family history of thyroid disease and 14 patients with unknown family history.Of the 77 patients,18(23.4%)patients achieved remission of treatment with methimazole and 59 patients did not;moreover,51(66.2%)had Graves’ophthalmopathy.Univariate analyses revealed no significant differences between the remission group and non-remission group in terms of age at diagnosis,sex,initial goiter size,or initial thyroid hormone concentration.However,there were a trend of correlation between the initial level of thyroid peroxidase antibody(TPOAb)and remission status(univariate analysis OR 1.002,P=0.038;multivariate analysis OR 1.004,P=0.019).Similar results were observed in univariate analysis of the initial thyrotropin receptor antibody(TRAb)level,but this association was not significant in multivariate analysis.Cox regression analyses revealed that children with high TRAb level required longer duration of remission,compared with low TRAb level(OR 0.950,95%CI 0.904-0.997,P=0.037).Interpretation:Initial TRAb level was an independent predictor of remission outcome in young children under the age of 7 years with GD.Initial TRAb level may predict the likelihood of remission in patients with young-age-of-onset GD. | Yi Gu Xuejun Liang Ming Liu Di Wu Wenjing Li Bingyan Cao Yuchuan Li Chang Su Jiajia Chen Chunxiu Gong | 2020 | Pediatric Investigation2020，4，3： | 3 |
| 9 | EAST-Educational Adaptive-optics Solar Telescope显示文摘For the public having a better understanding of solar activities,the Educational Adaptive-optics Solar Telescope(EAST)was built in July 2021 and is located at the Shanghai Astronomy Museum.The EAST consists of a 65 cm aperture solar telescope with a 177-element adaptive optics system and two-channel high resolution imaging system at the Hαand TiO bands,in addition to three full disk solar telescopes at CaK,Hαand TiO bands equipped on the tube of the main telescope.In this paper,the configuration of the EAST is described.Its performance and on-sky observational results are presented.The EAST,to our knowledge,is the most advanced solar telescope for the popularization of science in the world.Due to its excellent performance,the data acquired by the EAST can also be used for research on solar physics and space weather prediction. | Changhui Rao Xuejun Rao Zhimao Du Hua Bao Cheng Li Jinlong Huang Youming Guo Libo Zhong Qing Lin Xin Ge Jinsheng Yang Xinlong Fan Yangyi Liu Dan Jia Xin Li Mei Li Ming Zhang Yuntao Cheng Jiahui Zhou Jiawen Yao Lanqiang Zhang Naiting Gu | 2022 | Research in Astronomy and Astrophysics2022，22，6： | 3 |
| 10 | Plant Resistance to Pest and Research Progress of Its Genetic Improvement显示文摘Pest damage is a significant factor that cuts agricultural production,and cultivation of pest-resistant varieties is the most economic and effective approach of controlling pest damage. Plant pest resistance includes antixenosis,antibiosis,and tolerance. Current popular methods for the genetic improvement of crop pest resistance are traditional breeding method,transgenic breeding,and molecular mark-assisted breeding. This paper introduced major mechanisms and genetic bases of plant pest resistance,and reviewed research progress of domestic and international genetic improvement of plant pest resistance,analyzed the problems and its development prospects. | Chen Manfeng Wang Xuejun Ge Hong Miao Yamei Wang Kaihua Gu Chunyan Meng Lingyang | 2015 | Plant Diseases and Pests2015，6，1： | 2 |
| 11 | Bright photon-pair source based on a silicon dual-Mach-Zehnder microring显示文摘Single photons and photon pairs are typically generated by spontaneous parametric down conversion or quantum dots;however,spontaneous four-wave mixing(SFWM)in silicon microring resonators[1]is also an appealing source of entangled photons,offering a strong cavity-enhanced nonlinear interactions while maintaining features,such as compact,simple to fabricate,and allowing for thermal tuning.However,silicon ring-resonators usually suffer from a trade-off between providing a high pair generation rate(PGR)and high extraction efficiency.To achieve high PGR,devices are generally operated with the signal and idler photons in the undercoupling regime and pump photons at the critical coupling point,while high extraction rates require the converted photons to be overcoupled.Therefore,the optimal conditions for achieving maximal output photon pair flux are critical coupling for the pump photons and overcoupling for the converted photons[2,3]. | Chao Wu YingWen Liu XiaoWen Gu XinXin Yu YueChan Kong Yang Wang XiaoGang Qiang JunJie Wu ZhiHong Zhu XueJun Yang Ping Xu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，2： | 2 |
| 12 | Laser mass spectrometry for high sensitive and multi-component analysis of exhaust gas from vehicles显示文摘Laser mass spectrometry is a newly developed method for pollutant detection. It combines resonance-enhanced multiphoton ionization (REMPI) and time-of-flight mass spectro- metry (TOF-MS). It may detect pollutants with high sensitivity, high selectivity and in a multi-component way. In this note, laser mass spectrometry was used to detect the pollutants in exhaust gases from vehicles. With one-color REMPI (at 266 nm), several aromatic hydrocarbons, including benzene, toluene, xylene, C3-benzene, etc., were detected. These substances were selectively ionized by (1+1) REMPI and their mass resolution was detected by a TOF mass spectrometer. And a quantitative analysis was achieved. | Liandi Zhang Jie Wei Haiyang Zheng Ziyao Li Zhuhong Xia Xuejun Gu Bin Zhang | 2001 | Chinese Science Bulletin2001，46，1： | 2 |
| 13 | A NEW APPROACH TO HOLISTIC NITROGEN MANAGEMENT IN CHINA显示文摘Since the 1980s,the widespread use of N fertilizer has not only resulted in a strong increase in agricultural productivity but also caused a number of environmental problems,induced by excess reactive N emissions.A range of approaches to improve N management for increased agricultural production together with reduced environmental impacts has been proposed.The 4R principles(right product,right amount,right time and right place)for N fertilizer application have been essential for improving crop productivity and N use efficiency while reducing N losses.For example,site-specific N management(as part of 4R practice)reduced N fertilizer use by 32%and increased yield by 5%in China.However,it has not been enough to overcome the challenge of producing more food with reduced impact on the environment and health.This paper proposes a new framework of food-chainnitrogen-management(FCNM).This involves good N management including the recycling of organic manures,optimized crop and animal production and improved human diets,with the aim of maximizing resource use efficiency and minimizing environmental emissions.FCNM could meet future challenges for food demand,resource sustainability and environmental safety,key issues for green agricultural transformation in China and other countries. | Xuejun LIU Zhenling CUI Tianxiang HAO Lixing YUAN Ying ZHANG Baojing GU Wen XU Hao YING Weifeng ZHANG Tingyu LI Xiaoyuan YAN Keith GOULDING David KANTER Robert HOWARTH Carly STEVENS Jagdish LADHA Qianqian LI Lei LIU Wim DE VRIES Fusuo ZHANG | 2022 | Frontiers of Agricultural Science and Engineering2022，9，3： | 2 |
| 14 | Survey of Safety Management Approaches to Unmanned Aerial Vehicles and Enabling Technologies显示文摘Unmanned aerial vehicle(UAV)has a rapid development over the last decade.However,an increasing number of severe flight collision events caused by explosive growth of UAV have drawn widespread concern.It is an important issue to investigate safety management approaches of UAVs to ensure safe and efficient operation.In this paper,we present a comprehensive overview of safety management approaches in large,middle and small scales.In large-scale safety management,path-planning problem is a crucial issue to ensure safety and ordered operation of UAVs globally.In middle-scale safety management,it is an important issue to study the conflict detection and resolution methods.And in small-scale safety management,real-time collision avoidance is the last line of ensuring safety.Moreover,a UAV can be regarded as a terminal device connected through communication and information network.Therefore,the enabling technologies,such as sensing,command and control communication,and collaborative decision-making control technology,have been studied in the last. | Xuejun Zhang Yanshuang Du Bo Gu Guoqiang Xu Yongxiang Xia | 2018 | Journal of Communications and Information Networks2018，3，4： | 1 |
| 15 | The investigation of electrospun polymer nanofibers as a solid-phase extraction sorbent for the determination of trazodone in human plasma显示文摘 | Xuejun Kang Cao Pan Qian Xu Yingfang Yao Yian Wang Dongjin Qi Zhongze Gu | 2007 | Analytica Chimica Acta2007，，1： | 1 |
| 16 | Fiber-packed SPE tips based on electrospun fibers显示文摘 | Yiyun Zhang Xuejun Kang Liqin Chen Chao Pan Yingfang Yao Zhong-Ze Gu | 2008 | Analytical and Bioanalytical Chemistry2008，，6： | 1 |
| 17 | A novel virus-like particle based on hepatitis B core antigen and substrate-binding domain of bacterial molecular chaper- one DnaK显示文摘 | XueJun Wang Kai Gu Qi Yan Xiong | 2009 | Vaccine2009，，： | 1 |
| 18 | Determination and Comparison of Monoamine Neurotransmitters in Rat Striatum by High Performance Liquid Chromatography with Fluorescence Detection显示文摘 | Jing Xiao Xuejun Kang Tao Li Xiao Huang Zhongze Gu | 2005 | Journal of US-China Medical Science2005，2，6： | 1 |
| 19 | Treatment of the wastewater containing low-level 241 Am using flocculation-microfiltration process显示文摘 | Gao Yong Zhao Jun Zhang Guanghui Zhang Dong Cheng Weiwen Yuan Guoqi Liu Xuejun Ma Bangzhong Zeng Junhui Gu Ping | 2004 | Separation and Purification Technology2004，，2： | 1 |
| 20 | O08 Problem-based learning in the School of Basic Medical Sciences, Peking University显示文摘 | Jiang Gu Xuejun Li You Wen Chunyan Chou Hong Zhu | 2006 | 中国药理通讯2006，23，2： | 1 |
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