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| 1 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
| 2 | Spatial gradient distributions of thermal shock-induced damage to granite显示文摘In this study,we attempted to investigate the spatial gradient distributions of thermal shock-induced damage to granite with respect to associated deterioration mechanisms.First,thermal shock experiments were conducted on granite specimens by slowly preheating the specimens to high temperatures,followed by rapid cooling in tap water.Then,the spatial gradient distributions of thermal shock-induced damage were investigated by computed tomography(CT)and image analysis techniques.Finally,the influence of the preheating temperature on the spatial gradients of the damage was discussed.The results show that the thermal shock induced by rapid cooling can cause more damage to granite than that induced by slow cooling.The thermal shock induced by rapid cooling can cause spatial gradient distributions of the damage to granite.The damage near the specimen surface was at a maximum,while the damage inside the specimen was at a minimum.In addition,the preheating temperature can significantly influence the spatial gradient distributions of the thermal shock-induced damage.The spatial gradient distribution of damage increased as the preheating temperature increased and then decreased significantly over 600C.When the preheating temperature was sufficiently high(e.g.800C),the gradient can be ignored. | Lifeng Fan Jingwei Gao Xiuli Du Zhijun Wu | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，5： | 11 |
| 3 | Local icariin application enhanced periodontal tissue regeneration and relieved local inflammation in a minipig model of periodontitis显示文摘Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a promising compound for the enhancement of mesenchymal stem cell function, promotion of bone formation, inhibition of bone resorption, alleviation of inflammation and regulation of immunity. The study investigated the effect of icariin on periodontal tissue regeneration in a minipig model of periodontitis. The minipig model of periodontitis was established. Icariin was injected locally. The periodontal clinical assessment index, a computed tomography(CT) scan, histopathology and enzyme-linked immune sorbent assay(ELISA)were used to evaluate the effects of icariin. Quantitative analysis results 12 weeks post-injection demonstrated that probing depth,gingival recession, attachment loss and alveolar bone regeneration values were(3.72 ± 1.18) mm vs.(6.56 ± 1.47) mm,(1.67 ± 0.59)mm vs.(2.38 ± 0.61) mm,(5.56 ± 1.29) mm vs.(8.61 ± 1.72) mm, and(25.65 ± 5.13) mm3 vs.(9.48 ± 1.78) mm3 in the icariin group and0.9% NaCl group, respectively. The clinical assessment, CT scan, and histopathology results demonstrated significant enhancement of periodontal tissue regeneration in the icariin group compared to the 0.9% NaCl group. The ELISA results suggested that the concentration of interleukin-1 beta(IL-1β) in the icariin group was downregulated compared to the 0.9% NaCl group, which indicates that local injection of icariin relieved local inflammation in a minipig model of periodontitis. Local injection of icariin promoted periodontal tissue regeneration and exerted anti-inflammatory and immunomodulatory function. These results support the application of icariin for the clinical treatment of periodontitis. | Xiuli Zhang Nannan Han Guoqing Li Haoqing Yang Yangyang Cao Zhipeng Fan Fengqiu Zhang | 2018 | International Journal of Oral Science2018，10，3： | 9 |
| 4 | Investigation on experimental load spectrum for high and low cycle combined fatigue test显示文摘As the outfield load spectrum is so complicated that it cannot be used directly for test study in laboratory.This paper presents a method to determine load spectrum for high and low cycle combined fatigue of turbine mortise at elevated temperature through experimental and numerical method.First of all,the low cycle load spectrum with duration time is determined through cumulative damage rule.The rain flow counting method is applied to obtain main cycles and sub cycles,and then the stress cycle is converted into pulsation cycle(stress ratio=0)based on the S-N curve and the Goodman curve;Secondly,three groups of different amplitudes tests are established to determine the high cycle amplitude.Finally,another three groups of the high-low combined cycle fatigue(HLCCF)tests for turbine mortise of a certain type engine are carried out.The results show that the macro and micro failure modes are identical with outfield's,which verifies the accuracy of the conversion method. | Rongqiao Wang Jiaming Wei Dianyin Hu Xiuli Shen Jiang Fan | 2013 | Propulsion and Power Research2013，2，4： | 4 |
| 5 | High?Index?Faceted Ni_3S_2 Branch Arrays as Bifunctional Electrocatalysts for Efficient Water Splitting显示文摘For efficient electrolysis of water for hydrogen generation or other valueadded chemicals, it is highly relevant to develop low-temperature synthesis of low-cost and high-e ciency metal sulfide electrocatalysts on a large scale. Herein, we construct a new core–branch array and binder-free electrode by growing Ni_3S_2 nanoflake branches on an atomic-layer-deposited(ALD) TiO_2 skeleton. Through induced growth on the ALD-TiO_2 backbone, cross-linked Ni_3S_2 nanoflake branches with exposed { 210} highindex facets are uniformly anchored to the preformed TiO_2 core forming an integrated electrocatalyst. Such a core–branch array structure possesses large active surface area, uniform porous structure, and rich active sites of the exposed { 210 } high-index facet in the Ni_3S_2 nanoflake. Accordingly, the TiO_2@Ni_3S_2 core/branch arrays exhibit remarkable electrocatalytic activities in an alkaline medium, with lower overpotentials for both oxygen evolution reaction(220 mV at 10 mA cm^(-2)) and hydrogen evolution reaction(112 m V at 10 mA cm^(-2)), which are better than those of other Ni_3S_2 counterparts. Stable overall water splitting based on this bifunctional electrolyzer is also demonstrated. | Shengjue Deng Kaili Zhang Dong Xie Yan Zhang Yongqi Zhang Yadong Wang Jianbo Wu Xiuli Wang Hong Jin Fan Xinhui Xia Jiangping Tu | 2019 | Nano-Micro Letters2019，11，1： | 2 |
| 6 | Exome sequencing reveals genetic architecture in patients with isolated or syndromic short stature显示文摘Short stature is among the most common endocrinological disease phenotypes of childhood and may occur as an isolated finding or in conjunction with other clinical manifestations.Although the diagnostic utility of clinical genetic testing in short stature has been implicated,the genetic architecture and the utility of genomic studies such as exome sequencing(ES)in a sizable cohort of patients with short stature have not been investigated systematically.In this study,we recruited 561 individuals with short stature from two centers in China during a 4-year period.We performed ES for all patients and available parents.All patients were retrospectively divided into two groups:an isolated short stature group(group I,n=257)and an apparently syndromic short stature group(group II,n=304).Causal variants were identified in 135 of 561(24.1%)patients.In group I,29 of 257(11.3%)of the patients were solved by variants in 24 genes.In group II,106 of 304(34.9%)patients were solved by variants in 57 genes.Genes involved in fundamental cellularprocess played an important role in the genetic architecture of syndromic short stature.Distinct genetic architectures and pathophysiological processes underlie isolated and syndromic short stature. | Xin Fan Sen Zhao Chenxi Yu Di Wu Zihui Yan Lijun Fan Yanning Song Yi Wang Chuan Li Yue Ming Baoheng Gui Yuchen Niu Xiaoxin Li Xinzhuang Yang Shiyu Luo Qiang Zhang Xiuli Zhao Hui Pan Mei Li Weibo Xia Guixing Qiu Pengfei Liu Shuyang Zhang Jianguo Zhang Zhihong Wu James R.Lupski Jennifer E.Posey Shaoke Chen Chunxiu Gong Nan Wu | 2021 | Journal of Genetics and Genomics2021，48，5： | 2 |
| 7 | Citric acid-assisted synthesis of nano-Ag/BiO Br with enhanced photocatalytic activity显示文摘In this study, silver nano-particles have been anchored in the surface of Bi OBr photocatalysts by a citric acid-assisted photoreduction method. The citric acid was served as a chelating and reductive agent for the preparation of Ag-decorated Bi OBr photocatalysts(named as Ag/Bi OBr-2). The as-synthesized samples were characterized by X-ray diffraction(XRD), X-ray photoelectron spectroscopy(XPS), scanning electron microscopy(SEM), transmission electron microscopy(TEM), and UV-Vis diffuse reflection spectroscopy(DRS). The Ag/Bi OBr-2 photocatalyst exhibited excellent and stable photocatalytic activities on MO and phenol degradation under simulated sunlight irradiation. The enhanced photocatalytic activity could be ascribed to the smaller size, rough surface, and the surface plasma resonance(SPR) effect of Ag. Also, the Schottky junction, between the surface of the Bi OBr and silver nanoparticles, accelerated the efficient transfer and separation of photoinduced electron-hole pairs and promoted the photocatalytic performance. The active species tests indicated that the superoxide radical(·O-2) was responsible for the enhanced photocatalytic performance of Ag/Bi OBr-2. Finally, a possible photocatalytic mechanism was proposed. | Xiuli Li Xiaoming Mao Xiaochao Zhang Yunfang Wang Yawen Wang Hui Zhang Xiaogang Hao Caimei Fan | 2015 | Science China Chemistry2015，58，3： | 2 |
| 8 | Correction to:High‑Index‑Faceted Ni3S2 Branch Arrays as Bifunctional Electrocatalysts for Efficient Water Splitting显示文摘In the original publication,Figure S4 is an ancillary image to compare the specific surface areas of TiO2/Ni3S2 and Ni3S2 samples and it was incorrectly published.To better serve our readers,the correct figure is provided in this correction.The BET values are correct and unaffected.The corresponding figure caption,data analysis and conclusions are not affected and thus not to be changed.The authors would like to apologize for any inconvenience caused. | Shengjue Deng Kaili Zhang Dong Xie Yan Zhang Yongqi Zhang Yadong Wang Jianbo Wu Xiuli Wang Hong Jin Fan Xinhui Xia Jiangping Tu | 2021 | Nano-Micro Letters2021，13，1： | 1 |
| 9 | Waterborne polyurethane/O-MMT nanocomposites for flame retardant leather finishing 显示文摘 | Zhang Xiuli Chen Yi Fan Haojun | 2010 | Journal of the Society of Leather Technologists and Chemists2010，94，2： | 1 |
| 10 | Roles of cocatalysts in Pt–PdS/CdS with exceptionally high quantum efficiency for photocatalytic hydrogen production显示文摘 | Jinhui Yang Hongjian Yan Xiuli Wang Fuyu Wen Zhijun Wang Dayong Fan Jingying Shi Can Li | 2012 | Journal of Catalysis2012，，： | 1 |
| 11 | Increasing Winter Conductive Heat Transfer in the Arctic Sea-ice-covered Areas: 1979–2014显示文摘Sea ice is a quite sensitive indicator in response to regional and global climate changes. Based on monthly mean PanArctic Ice Ocean Modeling and Assimilation System(PIOMAS) sea ice thickness fields, we computed the conductive heat flux(CHF) in the Arctic Ocean in the four winter months(November–February) for a long period of 36 years(1979–2014). The calculated results for each month manifest the increasing extension of the domain with high CHF values since 1979 till 2014. In 2014, regions of roughly 90% of the central Arctic Ocean have been dominated by the CHF values larger than 18 Wm^(-2)(November–December) and 12 Wm^(-2)(January–February), especially significant in the shelf seas around the Arctic Ocean. Moreover, the population distribution frequency(PDF) patterns of the CHF with time show gradually peak shifting toward increased CHF values. The spatiotemporal patterns in terms of the trends in sea ice thickness and other three geophysical parameters, surface air temperature(SAT), sea ice thickness(SIT), and CHF, are well coupled. This suggests that the thinner sea ice cover preconditions for the more oceanic heat loss into atmosphere(as suggested by increased CHF values), which probably contributes to warmer atmosphere which in turn in the long run will cause thinner ice cover. This represents a positive feedback mechanism of which the overall effects would amplify the Arctic climate changes. | FAN Xieyu BI Haibo WANG Yunhe FU Min ZHOU Xuan XU Xiuli HUANG Haijun | 2017 | Journal of Ocean University of China2017，16，6： | 1 |
| 12 | Waterborne polyurethane/O-MMT nanocomposites for flame retardant leather finishing显示文摘 | Zhang Xiuli Chen Yi Fan Haojun Shi Bi | | 0，，02： | 1 |
| 13 | Influences of multiwalled carbon nanotubes and plant residue chars on bioaccumulation of polycyclic aromatic hydrocarbons by Chironomus plumosus larvae in sediment显示文摘 | Mohai Shen Xinghui Xia Fan Wang Pu Zhang Xiuli Zhao | 2012 | Environmental Toxicology and Chemistry2012，，1： | 1 |
| 14 | A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis显示文摘 | Li‐Dong Wang Xiuli Bi Xin Song Nicole M. Pohl Yulan Cheng Yixing Zhou Stephen Shears Emmanuel Ansong Mengtao Xing Shaomeng Wang Xiao‐Chun Xu Peng Huang Liyan Xu Liang Wang Zongmin Fan Xueke Zhao Huali Dong Stephen J. Meltzer Ivan Ding Wancai Yang | 2013 | Mol Carcinog2013，，1： | 1 |
| 15 | Hierarchical biomineralization of calcium carbonate regulated by silk microspheres显示文摘 | Xiuli Zhang Zhihai Fan Qiang Lu< !--Q4: Please check email address.--> Yongli Huang David L. Kaplan Hesun Zhu | 2013 | Acta Biomaterialia2013，，6： | 1 |
| 16 | Dewatering of sewage sludge using thermal compression 显示文摘 | FAN Li ZHOU Mingyuan LI Xiuli | 2012 | Applied Mecha- nics and Materials2012，，193194： | 1 |
| 17 | Recovering tail mine from a coal preparation plant using non-phase-change thermo-compression drying technology 显示文摘 | ZHOU Mingyuan FAN Li LI Xiuli | 2012 | Advanced Ma- terials Research2012，，361362363： | 1 |
| 18 | Modification of collagen for high Cr (Ⅲ) adsorption 显示文摘 | Luo Zhaoyang Zhang Xiuli Fan Haojun | 2009 | Journal of the A- merican Leather Chemists Association2009，104，4： | 1 |
| 19 | Hierarchical biomineralization of calcium carbonate regulated by silk micro spheres显示文摘 | ZHANG Xiuli FAN Zhihai LU Qiang | 2013 | Acta Biomater2013，9，6： | 1 |
| 20 | Adsorption Mechanism of Acetylene Hydrogenation on the Pd (111) Surface显示文摘First-principles calculations are carried out to examine the adsorption of acetylene over the Pd(111)surface.A hydrogen adsorption system is initially investigated to confirm the reliability of the selected calculation method.Adsorption energies,Mulliken-populations,overlap populations,charge density,and projected density of states(PDOS)are then calculated in the optimised acetylene adsorption system.Results show that C_(2)H_(2) molecule tends to adsorb through the threefold parallel-bridge configuration that is computed to be the most stable.In this structure,the distance of the C-H bond is calculated to be 1.09 Å,and the C-C-H bond angle is 128°.The distance of the C-C bond in acetylene is 1.36 Å,increasing from 1.21 Å in the gas phase.Moreover,the C-C bond overlap population decreases from 1.98 to 1.38,revealing that the carbon configuration in C2H2 rehybridises from sp to sp^(2) and beyond.The obtained results are compared with available experimental studies on acetylene hydrogenation on single-metal surfaces.The PDOS study indicates that a carbonaceous layer may generate on the metal surface during acetylene adsorption.The carbonaceous layer can affect the adsorption and reaction of acetylene,thereby inactivating the metal surface.Our experiments also show that Pd exhibits high catalytic activity. | Xuejia Xie Xiuli Song Wenyan Dong Zhenhai Liang Caimei Fan Peide Han | 2014 | Chinese Journal of Chemistry2014，32，7： | 1 |
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