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| 1 | Visualization Experiments of a Specific Fuel Flow Through Quartz-glass Tubes Under both Sub- and Supercritical Conditions显示文摘The present work is a visualization study of a typical kerosene (RP-3) flowing through vertical and horizontal quartz-glass tubes under both suband supercritical conditions by a high speed camera. The experiments are accomplished at temperatures of 300-730 K under pressures from 0.107-5 MPa. Six distinctive two-phase flow patterns are observed in upward flow and the critical point of RP-3 is identified as critical pressure pc=2.33 MPa and critical temperature Tc=645.04 K and it is found that when the fluid pressure exceeds 2.33 MPa the flow can be considered as a single phase flow. The critical opalescence phenomenon of RP-3 is observed when the temperature is between 643.16 K and 648.61 K and the pressure is between 2.308 MPa and 2.366 MPa. The region filled by the critical opalescence in the upward flow is clearly larger than that in the downward flow due to the interaction between the buoyancy force and fluid inertia. Morecover, obvious layered flow phenomenon is observed in horizontal flow under supercritical pressures due to the differences of gravity and density. | DENG Hongwu ZHANG Chunben XU Guoqiang TAO Zhi ZHU Kun WANG Yingjie | 2012 | Chinese Journal of Aeronautics2012，25，3： | 18 |
| 2 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
| 3 | An experimental study of the incipient bed shear stress partition in mobile bed channels filled with emergent rigid vegetation显示文摘This paper investigates the bed shear stress based on the condition of the incipient motion of sediment in a uniform-flow flume covered with emergent rigid vegetation,which is represented by arrays of circular cylinders arranged in a regular pattern.A total of 148 tests are performed to observe the influence of the vegetation density,bed slope,flow depth and sediment size on the bed shear stress.The tests reveal that when the sediment is in incipient motion,the resistances acting on the flow passing the rigid vegetation contain the vegetation resistance and the bed shear stress.This shear stress could be divided into two parts:the grain shear stress and the shear stress caused by sand dunes,which are the deformed bedform with the sediment incipient motion.An empirical relationship between the shear stress of the sand dune and vegetation density,the Froude number,the apparent vegetation layer velocity is developed. | WANG Hao TANG HongWu YUAN SaiYu LV ShengQi ZHAO XuanYu | 2014 | Science China(Technological Sciences)2014，57，6： | 10 |
| 4 | Force-induced charge carrier storage:a new route for stress recording显示文摘Stress sensing is the basis of human-machine interface,biomedical engineering,and mechanical structure detection systems.Stress sensing based on mechanoluminescence(ML)shows significant advantages of distributed detection and remote response to mechanical stimuli and is thus expected to be a key technology of next-generation tactile sensors and stress recorders.However,the instantaneous photon emission in ML materials generally requires real-time recording with a photodetector,thus limiting their application fields to real-time stress sensing.In this paper,we report a force-induced charge carrier storage(FICS)effect in deep-trap ML materials,which enables storage of the applied mechanical energy in deep traps and then release of the stored energy as photon emission under thermal stimulation.The FICS effect was confirmed in five ML materials with piezoelectric structures,efficient emission centres and deep trap distributions,and its mechanism was investigated through detailed spectroscopic characterizations.Furthermore,we demonstrated three applications of the FICS effect in electronic signature recording,falling point monitoring and vehicle collision recording,which exhibited outstanding advantages of distributed recording,longterm storage,and no need for a continuous power supply.The FICS effect reported in this paper provides not only a breakthrough for ML materials in the field of stress recording but also a new idea for developing mechanical energy storage and conversion systems. | Yixi Zhuang Dong Tu Changjian Chen Le Wang Hongwu Zhang Hao Xue Conghui Yuan Guorong Chen Caofeng Pan Lizong Dai Rong-Jun Xie | 2020 | Light(Science & Applications)2020，9，1： | 10 |
| 5 | Biodegradation of nicosulfuron by a novel Alcaligenes faecalis strain ZWS11显示文摘A bacterial strain ZWS11 was isolated from sulfonylurea herbicide-contaminated farmland soil and identified as a potential nicosulfuron-degrading bacterium. Based on morphological and physicochemical characterization of the bacterium and phylogenetic analysis of the 16 S r RNA sequence, strain ZWS11 was identified as Alcaligenes faecalis. The effects of the initial concentration of nicosulfuron, inoculation volume, and medium p H on degradation of nicosulfuron were investigated. Strain ZWS11 could degrade 80.56% of the initial nicosulfuron supplemented at 500.0 mg/L under the conditions of p H 7.0, 180 r/min and30°C after incubation for 6 days. Strain ZWS11 was also capable of degrading rimsulfuron,tribenuron-methyl and thifensulfuron-methyl. Four metabolites from biodegradation of nicosulfuron were identified, which were 2-aminosulfonyl-N, N-dimethylnicotinamide(M1), 4, 6-dihydroxypyrimidine(M2), 2-amino-4, 6-dimethoxypyrimidine(M3) and2-(1-(4,6-dimethoxy-pyrimidin-2-yl)-ureido)-N,N-dimethyl-nicotinamide(M4). Among the metabolites detected, M2 was reported for the first time. Possible biodegradation pathways of nicosulfuron by strain ZWS11 were proposed. The degradation proceeded mainly via cleavage of the sulfonylurea bridge, O-dealkylation, and contraction of the sulfonylurea bridge by elimination of a sulfur dioxide group. The results provide valuable information for degradation of nicosulfuron in contaminated environments. | Weisong Zhao Chen Wang Li Xu Chunqing Zhao Hongwu Liang Lihong Qiu | 2015 | Journal of Environmental Sciences2015，27，9： | 9 |
| 6 | Quadrilateral isoparametric finite elements for plane elastic Cosserat bodies显示文摘4-node, 8-node and 8(4)-node quadrilateral plane isoparametric elements are used for the solution of bound ary value problems in linear isotropic Cosserat elasticity. The patch test is applied to validate the finite elements. Engineering problems of stress concentration around a circular hole in plane strain condition and mechanical behaviors of heterogeneous materials with rigid inclusions and pores are computed to test the accuracy and capability of these three types of finite elements. | Hongwu Zhang Hui Wang Guozhen Liu | 2005 | Acta Mechanica Sinica2005，21，4： | 8 |
| 7 | Factors affecting genomic selection revealed by empirical evidence in maize显示文摘Genomic selection(GS) as a promising molecular breeding strategy has been widely implemented and evaluated for plant breeding, because it has remarkable superiority in enhancing genetic gain, reducing breeding time and expenditure, and accelerating the breeding process. In this study the factors affecting prediction accuracy(rMG) in GS were evaluated systematically, using six agronomic traits(plant height, ear height, ear length, ear diameter,grain yield per plant and hundred-kernel weight) evaluated in one natural and two biparental populations. The factors examined included marker density, population size, heritability,statistical model, population relationships and the ratio of population size between the training and testing sets, the last being revealed by resampling individuals in different proportions from a population. Prediction accuracy continuously increased as marker density and population size increased and was positively correlated with heritability; rMGshowed a slight gain when the training set increased to three times as large as the testing set. Low predictive performance between unrelated populations could be attributed to different allele frequencies, and predictive ability and prediction accuracy could be improved by including more related lines in the training population. Among the seven statistical models examined, including ridge regression best linear unbiased prediction(RR-BLUP), genomic BLUP(GBLUP), Bayes A, Bayes B, Bayes C, Bayesian least absolute shrinkage and selection operator(Bayesian LASSO), and reproducing kernel Hilbert space(RKHS), the RKHS and additive-dominance model(Add + Dom model) showed credible ability for capturing non-additive effects, particularly for complex traits with low heritability. Empirical evidence generated in this study for GS-relevant factors will help plant breeders to develop GS-assisted breeding strategies for more efficient development of varieties. | Xiaogang Liu Hongwu Wang Hui Wang Zifeng Guo Xiaojie Xu Jiacheng Liu Shanhong Wang Wen-Xue Li Cheng Zou Boddupalli M.Prasanna Michael S.Olsen Changling Huang Yunbi Xu | 2018 | The Crop Journal2018，6，4： | 8 |
| 8 | QTL analysis of ear leaf traits in maize(Zea mays L.)under different planting densities显示文摘Modem maize varieties have become more productive than ever, owing largely to increased tolerance of high plant density. However, the genetics of ear leaf traits under different densities remains poorly understood. In this study, Zhongdan 909 recombinant inbred lines(RILs) derived from a cross between Z58 and HD568 were genotyped for 3072 single-nucleotide polymorphisms(SNPs), and phenotyped for leaf length(LL), leaf width(LW), and leaf angle(LA) of the uppermost ear leaf under three planting densities(52,500,67,500, and 82,500 plants ha-1, respectively). A genetic map was then constructed using1358 high-quality SNPs. The total length of the linkage map was 1985.2 cM and the average interval between adjacent markers 1.46 cM. With increasing density, LL and LW decreased from 63.68 to 63.02 cm and from 8.56 to 8.21 cm, respectively, while LA increased from19.42° to 19.66°. All three traits had high heritabilities, of 0.75, 0.78, and 0.84, respectively.Using inclusive composite interval mapping, 23, 25, and 17 quantitative trait loci(QTL) were detected for LL, LW, and LA, respectively. Of these, 35 were simultaneously detected under two or three plant densities, while 30 were detected under only one. Sixty-five individual QTL explained 2.41% to 16.53% of phenotypic variation, while eight accounted for >10%.These findings will help us understand the genetic basis of leaf traits in maize as well as the response of maize to increased plant density. | Hongwu Wang Qianjin Liang Kun Li Xiaojiao Hu Yujin Wu Hui Wang Zhifang Liu Changling Huang | 2017 | The Crop Journal2017，5，5： | 7 |
| 9 | Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization显示文摘甾醇规章的元素绑定蛋白质(SREBP ) 抄写因素是在哺乳动物和在真菌的 hypoxic 改编的氧应答的管理者的细胞的类脂化合物动态平衡的主人管理者。SREBP C 终点绑在 SREBP 激活劈开的蛋白质(SCAP ) 的 WD40 领域,它由在 Golgi 控制到激活的朊酶的 SREBP-SCAP 建筑群和存取的 ER-to-Golgi 运输授与甾醇规定。这里,我们生物化学地并且在结构上表演 Sre1 和 Scp1,分裂酵母 SREBP 和 SCAP 的 carboxyl 终端域(CTD ) ,形成功能的 4:4 oligomer 和 Sre1-CTD 形式一 dimers 更暗淡。在 3.5 Å 的 Sre1-CTD 的水晶结构;并且在 5.4 Å 的建筑群的 cryo 他们结构;和在 vitro 生物化学的证据阐明在为 Scp1 绑定, Sre1-CTD dimerization 和 tetrameric 要求的 Sre1-CTD 的三个不同区域形成。最后,这些在结构上鉴别领域在细胞的上下文被验证,证明合适的 4:4 oligomeric 建筑群形成为 Sre1 激活被要求。 | Xin Gong Hongwu Qian Wei Shao Jingxian Li Jianping Wu Jun-Jie Liu Wenqi Li Hong-Wei Wang Peter Espenshade Nieng Yan | 2016 | Cell Research2016，26，11： | 6 |
| 10 | Large-eddy simulation of the generation and propagation of internal solitary waves显示文摘A modified large-eddy simulation model,the dynamic coherent eddy model(DCEM)is employed to simulate the generation and propagation of internal solitary waves(ISWs)of both depression and elevation type,with wave amplitudes ranging from small,medium to large scales.The simulation results agree well with the existing experimental data.The generation process of ISWs is successfully captured by the DCEM method.Shear instabilities and diapycnal mixing in the initial wave generation phase are observed.The dissipation rate is not equal at different locations of an ISW.ISW-induced velocity field is analyzed in the present study.The structure of the bottom boundary layer(BBL)of internal wave packets is found to be different from that of a single ISW.A reverse boundary jet instead of a separation bubble exists behind the leading internal wave while separation bubbles appear in other parts of the wave-induced velocity field.The boundary jet flow resulting from the adverse pressure gradients has distinctive dynamics compared with free shear jets. | ZHU Hai WANG LingLing TANG HongWu | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，6： | 6 |
| 11 | A novel dynamic coherent eddy model and its application to LES of a turbulent jet with free surface显示文摘We has developed a novel dynamic coherent eddy model,in which the coherent structure-Q criterion introduced by Hunt et al(1988)-is taken into account in the subgrid-scale turbulent viscosity based on the eddy viscosity model.One proposed method is to combine the resolved-scale velocity-gradient tensor in the classical Smagorinsky model with Q criterion weighted.A kind of dynamic procedure which was averaged in a general process at temporal direction based on the autocorrelations of the characteristic resolved scales of turbulence was taken for the coefficient of subgrid model.The model is implemented in the σ-coordinate and the filtered Navier-Stokes equations are solved by the operator splitting method.The validation was explored to 2-D turbulent slot jet both in ambient environment and in regular waves.The prediction of the present model was compared with the experiment data,including the averaged velocity profiles,the velocity fluctuations and the Reynolds stress.The model performance is shown to be satisfactory. | LU Jun,TANG HongWu,WANG LingLing & PENG Feng College of water conservancy of hydro-power engineering,Hohai University,Nanjing 210098,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，9： | 6 |
| 12 | Wide river or narrow river:Future river training strategy for Lower Yellow River under global change显示文摘The choice of a river training strategy is extremely important for the Lower Yellow River(LYR). Currently,the wide-river training strategy applies in the training of the LYR. However, remarkable changes in the hydrological processes in the Yellow River basin, as well as immediate pressure from socio-economic development in the Yellow River basin, make it necessary to consider if there is a possibility to change the river training strategy from wide-river training to narrow-river training. This research investigates the impacts of different river training strategies on the LYR through numerical simulations. A onedimensional(1-D) model was used to simulate the fluvial processes for the future 50 years and a threedimensional(3-D) model was applied to study typical floods. The study focused on river morphology, the results show that if the present decreasing trend in both water discharge and sediment load persists, the deposition rate in the LYR will further decrease no matter what strategy is applied. Especially, narrowriver training can achieve the aim to increase the sediment transport capacity in the LYR compared with wide-river training. However, if the incoming water and sediment load recovers to the mean level of the last century, main channel shrinkage due to sedimentation inevitably occurs for both wide-river and narrow-river training. Most importantly, this study shows that narrow-river training reduces the deposition amount over the whole LYR, but it provides little help in alleviating the development of the'suspended river'. Instead, narrow-river training can cause aggradation in the transitional reach where the river pattern changes from highly wandering to meandering, further worsening the 'hump deposition' there. Because of uncertainty regarding future changes in hydrological processes in the Yellow River basin, and the lack of feasible engineering measures to mitigate 'suspended river' and'hump deposition' problems in the LYR, caution should be exercised with respect to changes in the river training strategy for the LYR. | Xiaonan Li Deyu Zhong Y.Joseph Zhang Yanjun Wang Yongqiang Wang Hongwu Zhang | 2018 | International Journal of Sediment Research2018，33，3： | 5 |
| 13 | Silica shell-assisted synthetic route for mono-disperse persistent nanophosphors with enhanced in vivo recharged near-infrared persistent luminescence显示文摘在红外线附近(NIR ) 坚持光的 nanoparticles 作为在 vivo 成像是有希望的为的没有背景的对比代理人的一个新班出现了。下一个关键障碍是为综合建立一个柔韧、可控制的方法有高光亮度和长坚持的持续时间的 monodisperse nanoparticles。此处,我们报导包含 SiO 2 壳的 coating/etching 获得小 NIR 高度坚持的光 ZnGa 2 O 4:Cr3+,Sn4+(ZGOCS ) nanoparticles。优化 ZGOCS nanoparticles 有 ~ 的优秀尺寸分布没有任何凝块和 NIR 的 15 nm 被 13.5 的一个因素提高的坚持的光,由于在在退火以后阻止 nanoparticle 凝块的 SiO 2 壳的关键角色。ZGOCS nanoparticles 有比以前报导的 ZnGa 2 是的 O 4:Cr3+(ZGC-1 ) nanoparticles 一根 NIR 坚持光的探针为在 vivo bioimaging。而且,从 ZGOCS nanoparticles 的坚持光的信号能被一根白 lightemitting 二极管反复与外部刺激在 situ 再装;因此, nanoparticles 对合适在 vivo 成像应用长期。我们的学习为与好 biocompatibility 制作新奇高效的光 nanoparticles 建议改进策略。 | Rui Zou Junjian Huang Junpeng Shi Lin Huang Xuejie Zhang Ka-Leung Wong Hongwu Zhang Dayong Jin Jing Wang Qiang Su | 2017 | Nano Research2017，10，6： | 5 |
| 14 | Specific Recognition of Breast Cancer Cells In Vitro Using Near Infrared-Emitting Long-Persistence Luminescent Zn_3Ga_2Ge_2O_(10):Cr^(3+)Nanoprobes显示文摘In this paper, near-infrared emitting long-persistence luminescent Zn3Ga2Ge2O10:Cr3?(ZGG) nanoparticles with diameters of 30–100 nm and bright luminescence were prepared by a sol–gel synthesis method. After the surface amination, the nanoparticles were further bioconjugated with breast cancer-specific monoclonal antibody(anti-Ep CAM) to form ZGG-Ep CAM nanoprobes which can specifically target breast cancer cell lines(MCF7) in vitro. The results of in vitro images show that the luminescence signals from the cells treated with ZGG-Ep CAM nanoprobes are stronger than those from cells treated with ZGG-unconjugated antibody, indicating that the prepared ZGG-Ep CAM nanoprobes possessed excellent specific recognition capability. Furthermore, due to their long afterglow properties, the imaging could persist more than 1 h. Therefore, these nanoprobes could not only provide a high specificity detection method for cancer cells but also realize the long-time monitoring. Developed near-infrared emitting long-persistence luminescent nanoprobes will be expected to find new perspectives for cell therapy research and diagnosis applications. | Jinlei Li Junpeng Shi Jiangshan Shen Huizi Man Mingxi Wang Hongwu Zhang | 2015 | Nano-Micro Letters2015，7，2： | 4 |
| 15 | Effect of burden and origin sites of premature ventricular contractions on left ventricular function by 7-day Holter monitor显示文摘Recent studies have shown that premature ventricular contractions(PVCs) could enlarge the heart,but its risk factors are incompletely understood as a single 24-hour recording cannot reflect the true PVC burden due to day-to-day variability.Our purpose was to investigate the effect of burden and origin sites on left ventricular(LV) function in patients with PVCs by 7-day Holter electrocardiography(ECG).From May 2012 to August2013,112 consecutive patients with PVCs were recruited from the authors' affiliated hospital.All patients received2-dimensional transthoracic echocardiography,12-lead routing ECG and 7-days Holter ECG.Serum N-terminal probrain natriuretic peptide(NT-proBNP) levels were measured.A total of 102 participants with PVCs were included in the final analysis.Origin of PVCs from the tricuspid annulus had the highest burden and NT-proBNP level.LV papillary muscle had a higher LV ejection fraction(EF) level and a lower LV end-systolic dimension(ESD) than other PVC foci(P<0.05).The high burden group had a higher LV end-diastolic dimension(EDD) and LVESD but lower LVEF than the other two groups(P<0.05).Female,older age,physical work,and history of PVCs had a significantly positive correlation with symptoms.Male,older age,physical work,and high burden were positive predictors of enlarged LVEDD,LVESD and higher serum NT-proBNP level,but lower LVEF.Seven-day dynamic ECG Holter monitor showed the true PVC burden on patients with PVCs.PVCs with a lower burden or origin from the LV papillary muscle and the fascicle were relatively benign,while PVCs with a higher burden or origin from the tricuspid annulus may lead to cardiac dysfunction. | Wenhua Xu Mingfang Li Minglong Chen Bing Yang Daowu Wang Xiangqing Kong Hongwu Chen Weizhu Ju Kai Gu Kejiang Cao Hailei Liu Qi Jiang Jiaojiao Shi Yan Cui Hong Wang | 2015 | The Journal of Biomedical Research2015，29，6： | 4 |
| 16 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 17 | The Construction of Active Source Repeated Monitoring in the Qilian Mountain, Gansu Province显示文摘The exciting source of the active source repeated monitoring is located in the Xiliushui Reservoir in Zhangye,Gansu Province. The system began operating normally on July 9,2015,and we had completed a period of 40 days of continuous excitation experiment before November 10,2015. Our results reveal that the airgun source has good consistency and repeatability,and the detective system of active source can record signal clearly. The construction of active source repeated exploration projects has achieved some results,which can provide valuable experience for the research of active source repeated exploration. The observation data we obtained makes it possible to follow the temporal and spatial variations of the deep structure of the Qilian Mountain areas. | Zhang Yuansheng Guo Xiao Qin Manzhong Liu Xuzhou Wei Congxin Shen Xuzhang Yan Wenhua Zou Rui Yin Liang Wang Yahong Sun Dianfeng Feng Hongwu Zhang Lifeng Guo Yingxia | 2016 | Earthquake Research in China2016，30，3： | 4 |
| 18 | Enhancing Genetic Gain through Genomic Selection: From Livestock to Plants显示文摘Although long-term genetic gain has been achieved through increasing use of modern breeding methods and technologies,the rate of genetic gain needs to be accelerated to meet humanity’s demand for agricultural products.In this regard,genomic selection(GS)has been considered most promising for genetic improvement of the complex traits controlled by many genes each with minor effects.Livestock scientists pioneered GS application largely due to livestock’s significantly higher individual values and the greater reduction in generation interval that can be achieved in GS.Large-scale application of GS in plants can be achieved by refining field management to improve heritability estimation and prediction accuracy and developing optimum GS models with the consideration of genotype-by-environment interaction and non-additive effects,along with significant cost reduction.Moreover,it would be more effective to integrate GS with other breeding tools and platforms for accelerating the breeding process and thereby further enhancing genetic gain.In addition,establishing an open-source breeding network and developing transdisciplinary approaches would be essential in enhancing breeding efficiency for small-and medium-sized enterprises and agricultural research systems in developing countries.New strategies centered on GS for enhancing genetic gain need to be developed. | Yunbi Xu Xiaogang Liu Junjie Fu Hongwu Wang Jiankang Wang Changling Huang Boddupalli MPrasanna Michael SOlsen Guoying Wang Aimin Zhang | 2020 | Plant Communications2020，1，1： | 4 |
| 19 | Clear-water local scouring around three piers in a tandem arrangement显示文摘Experiments of local scouring around three piers were carried out under steady clear-water conditions. We investigated the role of pier spacing and flow rate in scour depth and progression. The scour-hole depth around the upstream pier was the same as that for single piers and independent of pier spacing. The scour behavior of the middle and downstream piers progressed through a synchronous scouring region, a transition region, and a radical deviation region as the fluid velocity increased. The critical velocity from the synchronous scouring region to the transition region for the middle and downstream piers was the same, which linearly increased with pier spacing. The degree of deviation in the radical deviation region for the middle and downstream piers was dependent on the pier spacing. The critical velocity from the transition region to the radical deviation region for the middle pier increased with the pier spacing. When the spacing was larger than 11 times the diameter of a pier, the scour depths of the three-pier configuration were the same as for the single piers, which indicates the limit of inter-pier fluid–structure interaction. Finally, the data from this study are used to derive adjustment factors to predict the local scour depth around three piers. | WANG Hao TANG HongWu XIAO JiangFeng WANG Yao JIANG Sheng | 2016 | Science China(Technological Sciences)2016，59，6： | 3 |
| 20 | HGF percutaneous endocardial injection induces cardiomyocyte proliferation and rescues cardiac function in pigs显示文摘Objective:To investigate the effect of cardiomyocyte proliferation induced by human hepatocyte growth factor(HGF)in pigs with chronic myocardial infarction(CMI).Methods:A steerable,deflectable 7F catheter incorporating a 27-guage needle was advanced percutaneously to the left ventricular myocardium of 18 pigs with CMI.Pigs were randomized(1:1:1)to receive adenoviral vector HGF(total dose,1×1010 genome copies),which was administered as five injections into the infarcted myocardium(total,1.0 mL),or saline,or Ad-null(control groups).Injections were guided by Ensite NavX left ventricular electroanatomical mapping.HGF and cyclin proteins were detected by western blot and immunoprecipitation analysis.Histological and immunohistochemical analysis determined proliferating cardiomyocytes.Myocardial perfusion and cardiac function were estimated by Gated-Single Photon Emission Computed Tomography(G-SPECT).Results:Western blot analyses showed that HGF were predominantly expressed in the infarct core and border in the myocardium of the infarcted heart.G-SPECT analysis indicated that the HGF group had better cardiac function and myocardial perfusion four weeks after the injection of Ad-HGF than before the injection of Ad-HGF.After treatment there were more proliferating cardiomyocytes in the HGF group compared to either of the control groups.Furthermore,the HGF group myocardial samples expressed higher levels of p-Akt,cyclin A,cyclin E,cyclin D1,cdk2,cdk4 than those in the control groups.Conclusion:The over-expression of HGF activates pro-survival pathways,induces cardiomyocyte proliferation,and improves the perfusion and function of the porcine CMI heart. | Zhengxian Tao Bo Chen Yingming Zhao Hongwu Chen Liansheng Wang Yonghong Yong Kejiang Cao Qifeng Yu Danian Ke` Hua Wang Zuze Wu Zhijian Yang | 2010 | The Journal of Biomedical Research2010，24，3： | 3 |
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