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| 1 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 2 | A Decision-Making Method for Air Combat Maneuver Based on Hybrid Deep Learning Network显示文摘In this paper, a hybrid deep learning network-based model is proposed and implemented for maneuver decision-making in an air combat environment.The model consists of stacked sparse auto-encoder network for dimensionality reduction of high-dimensional,dynamic time series combat-related data and long shortterm memory network for capturing the quantitative relationship between maneuver control variables and the time series combat-related data after dimensionality reduction.This model features: using time series data as the basis of decision-making, which is more in line with the actual decision-making process;using stacked sparse auto-encoder network to reduce the dimension of time series data to predict the result more accurately;in addition, taking the maneuver control variables as the output to control the maneuver, which makes the maneuver process more flexible. The relevant experiments have demonstrated that the proposed model can effectively improve the prediction accuracy and convergence rate in the prediction of maneuver control variables. | LI Bo LIANG Shiyang CHEN Daqing LI Xitong | 2022 | Chinese Journal of Electronics2022，31，1： | 6 |
| 3 | Chemically modified magnetic chitosan microspheres for Cr(VI) removal from acidic aqueous solution显示文摘 | Xitong Sun Qian Li Liangrong Yang Huizhou Liua | 2016 | Particuology2016，14，3： | 4 |
| 4 | Understanding theDynamics of Service-Oriented Architecture Implementation显示文摘 | Xitong Li Stuart E Madnick | 2015 | Journal of Management Information Systems2015，32，2： | 1 |
| 5 | Online Healthcare Community Interaction Dynamics显示文摘With the increasing dilemma of the rapid global demand for healthcare services(often in the presence of limited resources),how to creatively allocate and use healthcare resources across a widespread population has become a salient issue.Online healthcare communities(OHCs)are regarded as a potential ICT-based partial solution.In contrast to traditional healthcare,online doctor-patient interaction is unlimited in terms of time and space limitations while an OHC is exposed to the whole community.These characteristics are key to achieving synergistic doctor-patient interaction and community development in the longer term.In order to explore the nature of doctor-patient interaction dynamics in an OHC,we systematically investigate doctor-patient interaction dynamics from the dual perspectives of doctor and patient.Our doctor-patient interaction dual-cycle model has been built based on six doctor-patient interaction processes(i.e.,searching,choosing,knowledge sharing,providing,receiving and balancing).According to our dual-cycle model,four key managerial issues in OHC(information asymmetry,incentive mechanisms,service delivery processes and interaction mechanisms)have been identified as examples.Discussion and directions for future research,with challenges as well as opportunities,have been elaborated.A broad view with fruitful research potential is ensured and new theories and methods ultimately provide implications for effectively and efficiently allocating scarce healthcare resources to a broader population. | Xitong Guo Shanshan Guo Douglas Vogel Yijun Li | 2016 | Journal of Management Science and Engineering2016，1，1： | 1 |
| 6 | Lower temperature hydrothermal pretreatment improves the anaerobic digestion performance of spent cow bedding显示文摘The anaerobic digestion(AD)performance of spent cow bedding was investigated with different hydrothermal pretreatment(HP)conditions.Spent cow bedding was pretreated with low temperatures(50,70,and 90℃)and different pretreatment times(2-72 h)with ammonia and without ammonia.The results showed that spent cow bedding was a good raw material for AD.After pretreatment,the concentration of volatile fatty acids(VFAs)in the group of hydrothermal pretreatments with ammonia(HPA)was higher than that in the HP group at the same pretreatment temperature and time.The optimal pretreatment condition was achieved with an HPA of 50℃ holding for 72 h.At the optimal condition,the highest concentration of VFAs was 1.58-10.85 times higher than that of the other pretreated groups.The highest hemicellulose and lignin removal rates were 58.07%and 10.32%,respectively.The highest methane yield was 163.0 ml(g· VS)^(-1),which was 48.9%higher than that of the untreated group.The VFAs,pH,and reducing sugars showed positive relationships with the methane yield.Therefore,HP at low temperature can enhance the AD performance of spent cow bedding. | Xitong Wang Hairong Yuan Xiaocong Song Xiujin Li Xiaoyu Zuo | 2021 | Chinese Journal of Chemical Engineering2021，34，11： | 1 |
| 7 | Amino-functionalized magnetic cellulose nanocomposite as adsorbent for removal of Cr(VI): Synthesis and adsorption studies显示文摘 | Xitong Sun Liangrong Yang Qian Li Junmei Zhao Xiaopei Li Xiaoqin Wang Huizhou Liu | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 8 | Polystyrene microsphere-immobilized palladium(Ⅱ)porphyrin as mild,reusable,and highly efficient catalyst for Heck reaction显示文摘A novel Heck reaction catalyst consisting of a palladium(Ⅱ) complex of meso-tetra(phydroxyphenyl)porphyrin(MTP) and cross-linked chloromethylated polystyrene microspheres(PMs) was successfully prepared via covalent ether bonds between the chloride groups in the PMs and the hydroxyl groups in MTP.The catalyst was characterized using scanning electron microscopy,Fourier-transform infrared spectroscopy,and inductively coupled plasma atomic emission spectroscopy(ICP-AES).This polystyrene-supported palladium-complex was an efficient heterogeneous catalyst for cross-coupling of aryl iodides with ethyl acrylate.The reaction of iodobenzene and ethyl acrylate under N_2 at 100 ℃ and a catalyst concentration of 0.1%gave a gas chromatography product yield of 99.8%,which is much higher than that achieved using a free palladium(Ⅱ) complex of MTP as the catalyst(41.3%).The catalyst was recycled up to six times without significant loss of catalytic activity.These results suggest that the immobilized palladium(Ⅱ)-MTP catalyst has potential applications in synthetic and industrial chemistry. | Yinbin Huang Liangrong Yang Minghui Huang Jian Wang Lin Xu Wensong Li Huacong Zhou Xitong Sun Huifang Xing Huizhou Liu | 2015 | Particuology2015，13，5： | 1 |
| 9 | Multidimensional context-aware so- cial network architecture for mobile crowdsensing显示文摘 | Hu Xiping Li Xitong Ngai E C | 2014 | IEEE Com- munications Magazine2014，52，6： | 1 |
| 10 | Perovskite/GaAs-nanowire hybrid structure photodetectors with ultrafast multiband response enhancement by band engineering显示文摘We developed a hybrid structure photodetector combining one-dimensional(1D)inorganic GaAs nanowires and two-dimensional(2D)organic perovskite materials,which can achieve various performance enhancements using a relatively simple structure.Via the optical absorption enhancement of perovskite and the type-II energy band structure formed by the heterostructure,the responsivity and detectivity of the photodetector from ultraviolet(UV)to visible(Vis)wavelengths are significantly enhanced,reaching 75 A/W and 1.49×10^(11)Jones,respectively.The response time of the photodetector was significantly decreased by 3 orders,from 785 ms to 0.5 ms,and the dark current was further reduced to 237 fA.A photodetector was prepared with enhanced responsivity and ultrafast response time in the multiband region from the UV to Vis wavelength.To the best of our knowledge,this is the first time to combine inorganicⅢ-ⅤGaAs nanomaterials with organic perovskite materials,which verifies the effective combination of inorganic and organic materials in a mixed dimension.The excellent photoelectric performance of the perovskite/GaAs-nanowire hybrid structure photodetector makes it a potential candidate material for a wide range of photoelectric applications such as multiband photodetection. | XIAOBING HOU XITONG HONG FENGYUAN LIN JINZHI CUI QIAN DAI QIANLEI TIAN BINGHENG MENG YANJUN LIU JILONG TANG KEXUE LI LEI LIAO ZHIPENG WEI | 2023 | Photonics Research2023，11，4： | 0 |
| 11 | Kinetically accelerated and high-mass loaded lithium storage enabled by atomic iron embedded carbon nanofibers显示文摘Carbonaceous materials represent the dominant choice of materials for anodic lithium storage in many energy storage devices.Nevertheless,the nonpolar carbonaceous materials offer weak adsorption toward Li+that largely denies the high-rate Li+storage.Herein,the atomic Fe sites decorated carbon nanofibers(AICNFs)facilely produced by electrospinning are reported for kinetically accelerated Li+storage.Theoretical calculation reveals that the atomic Fe sites possess coordination unsaturated electronic configuration,enabling suitable bonding energy and facilitated diffusion path of Li+.As a result,the optimal structure displays a high capacitive contribution up to 95.9%at a scan rate of 2.0 mV·s^(−1).In addition,ultrahigh capacity retention of 97%is afforded after 5,000 cycles at a current density of 3 A·g^(−1).Moreover,the interlaced fiber structure enabled by electrospinning benefits structural stability and improved conductivity even at thick electrodes,thus allowing a high areal capacity of 1.76 mAh·cm−2 at a loading of 8 mg·cm−2.Because of these structure and performance merits,the lithium-ion capacitor containing the AICNF-based anode delivers a high energy density and large power density. | Qian Xu Yanan Li Chenghao Wu Xitong Sun Qiang Li Huabin Zhang Le Yu Yuanyuan Pan Yujuan Wang Shiwei Guo Mengdi Zhang Han Hu Mingbo Wu | 2022 | Nano Research2022，15，7： | 0 |
| 12 | Flexible Diodes/Transistors Based on Tunable p-n-Type Semiconductivity in Graphene/Mn-Co-Ni-O Nanocomposites显示文摘We report a novel Mn-Co-Ni-O(MCN)nanocomposite in which the p-type semiconductivity of Mn-Co-Ni-O can be manipulated by addition of graphene.With an increase of graphene content,the semiconductivity of the nanocomposite can be tuned from p-type through electrically neutral to n-type.The very low effective mass of electrons in graphene facilitates electron tunneling into the MCN,neutralizing holes in the MCN nanoparticles.XPS analysis shows that the multivalent manganese ions in the MCN nanoparticles are chemically reduced by the graphene electrons to lower-valent states.Unlike traditional semiconductor devices,electrons are excited from the filled graphite band into the empty band at the Dirac points from where they move freely in the graphene and tunnel into the MCN.The new composite film demonstrates inherent flexibility,high mobility,short carrier lifetime,and high carrier concentration.This work is useful not only in manufacturing flexible transistors,FETs,and thermosensitive and thermoelectric devices with unique properties but also in providing a new method for future development of 2D-based semiconductors. | Lihong Su Zhou Yang Xitong Wang Ziao Zou Bo Wang Gary Hodes Ninghui Chang Yongyong Suo Zhibo Ma Haoxu Wang Yucheng Liu Junping Zhang Shuanhu Wang Yuefei Li Fengxia Yang Jixin Zhu Fei Gao Wei Huang Shengzhong Liu | 2022 | Research2022，，1： | 0 |
| 13 | PDA-BPs integrated mussel-inspired multifunctional hydrogel coating on PPENK implants for anti-tumor therapy,antibacterial infection and bone regeneration显示文摘Currently,many cancer patients with bone defects are still threatened by tumor recurrence,postoperative bacterial infection,and massive bone loss.Many methods have been studied to endow bone implants with biocompatibility,but it is difficult to find an implant material that can simultaneously solve the problems of anticancer,antibacterial and bone promotion.Here,a multifunctional gelatin methacrylate/dopamine methacrylate adhesive hydrogel coating containing 2D black phosphorus(BP)nanoparticle protected by polydopamine(pBP)is prepared by photocrosslinking to modify the surface of poly(aryl ether nitrile ketone)containing phthalazinone(PPENK)implant.The multifunctional hydrogel coating works in conjunction with pBP,which can deliver drug through photothermal mediation and kill bacteria through photodynamic therapy at the initial phase followed by promotion of osteointegration.In this design,photothermal effect of pBP control the release of doxorubicin hydrochloride loaded via electrostatic attraction.Meanwhile,pBP can generate reactive oxygen species(ROS)to eliminate bacterial infection under 808 nm laser.In the slow degradation process,pBP not only effectively consumes excess ROS and avoid apoptosis induced by ROS in normal cells,but also degrade into PO43to promote osteogenesis.In summary,nanocomposite hydrogel coatings provide a promising strategy for treatment of cancer patients with bone defects. | Yizheng Li Chengde Liu Xitong Cheng Jinyan Wang Yue Pan Cheng Liu Shouhai Zhang Xigao Jian | 2023 | Bioactive Materials2023，，9： | 0 |
| 14 | Experimental test and theoretical calculation of the fracture height limit of gas pipe flow to Darcy flow显示文摘Low-speed flow experiments in which ultra-fine copper tubes are used to simulate micro-fractures in carbonate strata are conducted to analyze the variations of gas flow state in fractures of different fracture heights,determine flow state transition limit and transition interval,and establish the calculation method of flow state transition limit.The results show that the ideal Hagen-Poiseuille flow is the main form of gas flow in large fractures.Due to the decrease of fracture height,the gas flow in the fracture changes from Hagen-Poiseuille flow with ideal smooth seam surface to non-Hagen-Poiseuille flow,and the critical point of the transition is the boundary of flow state transition.After the fracture height continues to decrease to a certain extent below the boundary of the flow state transition fracture height,the form of gas flow gradually changes to the ideal Darcy flow,thus the transition interval of the gas flow state in the closing process of fracture can be determined.Based on the three-dimensional microconvex body scanning of the fracture surface,the material properties of fracture and properties of fluid in the fracture,a method for calculating the boundary of flow state transition is established.The experimental test and theoretical calculation show that the limit of the fracture height for the transition from pipe flow to Darcy flow is about twice the sum of the maximum height of the microconvex bodies on the upper and lower sides of the fracture. | XIONG Yu FU Xitong LI Qian SUN Zewei ZHANG Chun ZHANG Fei | 2022 | Petroleum Exploration and Development2022，49，3： | 0 |
| 15 | Gas-assisted magnetic separation for the purification of proteins in batch systems显示文摘 | Zhini Liu Liangrong Yang Tingting Dong Wensong Li Xitong Sun Menghao Zhu Zhengkang Duan Qingfen Liu Huizhou Liu | 2016 | Particuology2016，14，1： | 0 |
| 16 | Flexible Diodes/Transistors Based on Tunable p-n-Type Semiconductivity in Graphene/Mn-Co-Ni-O Nanocomposites显示文摘We report a novel Mn-Co-Ni-O(MCN)nanocomposite in which the p-type semiconductivity of Mn-Co-Ni-O can be manipulated by addition of graphene.With an increase of graphene content,the semiconductivity of the nanocomposite can be tuned from p-type through electrically neutral to n-type.The very low effective mass of electrons in graphene facilitates electron tunneling into the MCN,neutralizing holes in the MCN nanoparticles.XPS analysis shows that the multivalent manganese ions in the MCN nanoparticles are chemically reduced by the graphene electrons to lower-valent states.Unlike traditional semiconductor devices,electrons are excited from the filled graphite band into the empty band at the Dirac points from where they move freely in the graphene and tunnel into the MCN.The new composite film demonstrates inherent flexibility,high mobility,short carrier lifetime,and high carrier concentration.This work is useful not only in manufacturing flexible transistors,FETs,and thermosensitive and thermoelectric devices with unique properties but also in providing a new method for future development of 2D-based semiconductors. | Lihong Su Zhou Yang Xitong Wang Ziao Zou Bo Wang Gary Hodes Ninghui Chang Yongyong Suo Zhibo Ma Haoxu Wang Yucheng Liu Junping Zhang Shuanhu Wang Yuefei Li Fengxia Yang Jixin Zhu Fei Gao Wei Huang Shengzhong Liu | 2021 | Research2021，，1： | 0 |
| 17 | Pomegranate peel polyphenols alleviate insulin resistance through the promotion of insulin signaling pathway in skeletal muscle of metabolic syndrome rats显示文摘Insulin resistance(IR) has been considered to be an important causative factor of metabolic syndrome(Met S). The present study investigated whether pomegranate peel polyphenols(PPPs) could prevent the development of Met S by improving IR in rats. Male Sprague-Dawley(SD) rats were fed high fat diet(HFD) to induce Met S and supplemented with different dosages of PPPs for 12 weeks. The results showed that HFD-induced insulin resistant rats had disordered metabolism of blood glucose, blood lipid, and terrible muscle fiber morphology when compared with normal diet-fed rats, but PPPs treatment at a dosage of 300 mg/kg·day significantly reversed these negative effects. Moreover, in skeletal muscle tissue of insulin resistant rats, PPPs treatments significantly increased the protein expressions of insulin receptor(Ins R) and phosphorylated insulin receptor substrate 1(IRS-1), stimulated peroxisome proliferator activated receptor gamma(PPARγ) and phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT/PKB) signaling pathway, and aggrandized the protein levels of phosphorylated glycogen synthase kinase-3β(GSK-3β) and glucose transporter 4(GLUT4). Our results suggest that PPPs possess of the beneficial effects on alleviating IR by enhancing insulin sensitivity and regulating glucose metabolism. | Xitong Zhang Lin Du Weimin Zhang Mi Yang Li Chen Chen Hou Jianke Li | 2022 | Food Science and Human Wellness2022，11，4： | 0 |
| 18 | Preparation of Iron-Pillared Bentonite/Oyster Shell Composite and Phosphate Adsorption in Water显示文摘Iron-pillared bentonite(FB)was prepared by Fe(III)modified bentonite,and then the composites(FB-OS)were prepared by iron-pillared bentonite and oyster shell powder.The composites were characterized by FTIR,SEM,TGA,and EDS,and the phosphorus removal test was carried out.The results showed that FB-OS contained a large amount of CaO.Its structure was compact,but there were gaps in it.The maximum bending stress and compressive strength were 43.7 N and 0.927 MPa,respectively.The phosphorus removal test showed that the phosphorus removal rate of FB-OS was more than 90%,and measured the maximum adsorption capacity was 48.31 mg/g.A large amount of spherical products were produced on the surface and inside of FB-OS after phos-phorus removal,it was speculated that spherical products were amorphous calcium phosphate in the paper.Ana-lysis indicated that there was chemical adsorption during phosphorus removal.The kinetic equation of phosphorus adsorption by FB-OS was qt=10:193t/1+2:574t (R^(2)=0.995).The adsorption rate was mainly controlled by outerfilm diffusion and intraparticle diffusion. | Zhijian Zhou Jie Yan Xinxiang Du Qiulin Xu Zijun Wu Jinlan Yang Xitong Fang Qiuling Zhong Qiaoguang Li | 2023 | Journal of Renewable Materials2023，11，9： | 0 |
| 19 | An overview of autophagy in the differentiation of dental stem cells显示文摘Dental stem cells(DSCs)have attracted significant interest as autologous stem cells since they are easily accessible and give a minimal immune response.These properties and their ability to both maintain self-renewal and undergo multi-lineage differentiation establish them as key players in regenerative medicine.While many regulatory factors determine the differentiation trajectory of DSCs,prior research has predominantly been based on genetic,epigenetic,and molecular aspects.Recent evidence suggests that DSC differentiation can also be influenced by autophagy,a highly conserved cellular process responsible for maintaining cellular and tissue homeostasis under various stress conditions.This comprehensive review endeavors to elucidate the intricate regulatory mechanism and relationship between autophagy and DSC differentiation.To achieve this goal,we dissect the intricacies of autophagy and its mechanisms.Subsequently,we elucidate its pivotal roles in impacting DSC differentiation,including osteo/odontogenic,neurogenic,and angiogenic trajectories.Furthermore,we reveal the regulatory factors that govern autophagy in DSC lineage commitment,including scaffold materials,pharmaceutical cues,and the extrinsic milieu.The implications of this review are far-reaching,underpinning the potential to wield autophagy as a regulatory tool to expedite DSC-directed differentiation and thereby promote the application of DSCs within the realm of regenerative medicine. | XITONG ZHAO TIANJUAN JU XINWEI LI CHANGFENG LIU LULU WANG LI-AN WU | 2024 | BIOCELL2024，48，1： | 0 |
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