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| 1 | PlantcircBase: A Database for Plant Circular RNAs显示文摘 | Qinjie Chu Xingchen Zhang Xintian Zhu Chen Liu Lingfeng Mao Chuyu Ye Qian-Hao Zhu Longjiang Fan | 2017 | Molecular Plant2017，10，8： | 15 |
| 2 | Deposition of FeCoNiCrMn high entropy alloy(HEA) coating via cold spraying显示文摘High entropy alloys(HEAs) are of great interest in the community of materials science and engineering due to their unique phase structure. They are constructed with five or more principal alloying elements in equimolar or near-equimolar ratio. Therefore, HEAs can derive their performance from multiple principal elements rather than a single element. In this work, solid-state cold spraying(CS) was applied for the first time to produce FeCoNiCrMn HEA coating. The experimental results confirm that CS can be used to produce a thick HEA coating with low porosity. As a low-temperature deposition process, CS completely retained the HEA phase structure in the coating without any phase transformation. The characterization also reveals that the grains in the CSed HEA coating had experienced significant refinement as compared to those in the as-received HEA powder due the occurrence of dynamic recrystallization at the highly deformed interparticle region. Due to the increased dislocation density and grain boundaries,CSed HEA coating was much harder than the as-received powder. The tribological study shows that the CSed FeCoNiCrMn HEA coating resulted in lower wear rate than laser cladded HEA coatings. | Shuo Yin Wenya Li Bo Song Xingchen Yan Min Kuang Yaxin Xu Kui Wen Rocco Lupoi | 2019 | Journal of Materials Science & Technology2019，35，6： | 13 |
| 3 | Effects of metabolizable energy and crude protein levels on laying performance,egg quality and serum biochemical indices of Fengda-1 layers显示文摘This study was conducted to investigate the effects of dietary ME and CP levels on laying performance, egg quality and serum biochemical indices of Fengda-1 layers. In a 2 × 3 factorial arrangement, 2,400 Fengda-1 layers(32 wk of age) were randomly assigned to 6 experimental diets with 2,650 and 2,750 kcal of ME/kg of diet, each containing 14.50%, 15.00% and 15.50% CP, respectively. Each dietary treatment was replicated 5 times, and feed and water were provided ad libitum. The trial lasted for 10 wk, including a2-week acclimation period and an 8-week experimental period. Our results showed that ADFI decreased as the ME level of diet increased from 2,650 to 2,750 kcal/kg(P< 0.05). Layers fed diets with 2,750 kcal/kg ME exhibited higher mortality than those fed with 2,650 kcal/kg ME(P < 0.05). Birds fed with 14.50% and15.00% CP had higher egg production(EP) and egg mass(EM) than those fed with 15.50% CP(P < 0.05).Yolk color increased as the ME level of the diet increased from 2,650 to 2,750 kcal/kg, however, the eggshell thickness decreased(P < 0.05). Serum concentrations of uric acid and triglyceride in layers fed diets with 2,750 kcal/kg ME were higher than those fed diets with 2,650 kcal/kg ME(P < 0.05). There was no significant interaction between ME and CP on laying performance, egg quality, or serum biochemical indices(P > 0.05). Based on the data under the experimental conditions, the optimal dietary ME and CP levels of Fengda-1 layers are 2,650 kcal/kg and 15.00%(33 to 41 wk of age). | Yang Ding Xingchen Bu Nannan Zhang Lanlan Li Xiaoting Zou | 2016 | Animal Nutrition2016，，2： | 11 |
| 4 | Selective laser melting(SLM)of CX stainless steel:Theoretical calculation,process optimization and strengthening mechanism显示文摘In the present work,selective laser melting(SLM)technology was utilized for manufacturing CX stainless steel samples under a series of laser parameters.The effect of laser linear energy density on the microstructure characteristics,phase distribution,crystallographic orientation and mechanical properties of these CX stainless steel samples were investigated theoretically and experimentally via scanning electron microscope(SEM),X-ray diffraction(XRD),electron backscatter diffraction(EBSD)and transmission electron microscope(TEM).Based on the systematic study,the SLM CX stainless steel sample with best surface roughness(Ra=4.05±1.8μm)and relative density(Rd=99.72%±0.22%)under the optimal linear density(η=245 J/m)can be obtained.SLM CX stainless steel was primarily constituted by a large number of fine martensite(α’phase)structures(i.e.,cell structures,cellular dendrites and blocky grains)and a small quantity of austenite(γphase)structures.The pre ferred crystallographic orientation(i.e.,<111>direction)can be determined in the XZ plane of the SLM CX sample.Furthermore,under the optimal linear energy density,the good combinations with the highest ultimate tensile strength(UTS=1068.0%±5.9%)and the best total elongation(TE=15.70%±0.26%)of the SLM CX sample can be attained.Dislocation strengthening dominates the strengthening mechanism of the SLM CX sample in as-built state. | Dongdong Dong Cheng Chang Hao Wang Xingchen Yan Wenyou Ma Min Liu Sihao Deng Julien Gardan Rodolphe Bolot Hanlin Liao | 2021 | Journal of Materials Science & Technology2021，，14： | 11 |
| 5 | Improving fatigue performance of Ti-6Al-4V alloy via ultrasonic surface rolling process显示文摘The effect of a gradient nanostructured(GNS) surface layer obtained by ultrasonic surface rolling process(USRP) on the fatigue behavior of Ti-6Al-4V alloy has been studied in this paper. Microstructure, surface topography, surface roughness and residual stress measurements were performed to characterize the surface under different conditions. Rotating bending fatigue tests were carried out to evaluate the fatigue behavior of different treatments. The results present a remarkable fatigue performance enhancement for the Ti-6Al-4V alloy with a GNS surface layer obtained by application of USRP with respect to the untreated condition, notwithstanding its considerable surface roughness due to severe ultrasonic impacts and extrusions. Mechanical surface polishing treatment further enhances the beneficial effects of USRP on the fatigue performance. The significantly improved fatigue performance can mainly be ascribed to the compressive residual stress. Simultaneously, the GNS surface layer and surface work hardening have a synergistic effect that accompanies the effect of compressive residual stress. | Chengsong Liu Daoxin Liu Xiaohua Zhang Dan Liu Amin Ma Ni Ao Xingchen Xu | 2019 | Journal of Materials Science & Technology2019，35，8： | 7 |
| 6 | Contribution of ultrasonic surface rolling process to the fatigue properties of TB8 alloy with body-centered cubic structure显示文摘The effect of ultrasonic surface rolling process(USRP) as a severe plastic deformation technology was investigated on the evolution of microstructure, residual stress and surface morphology of TB8 alloys with body-centered cubic structure. Stress-controlled rotating-bending fatigue tests indicated increased fatigue strength in USRP samples prepared using different number of passes compared to the base material, which was attributed to the presence of gradient structure surface layers. Five subsequent USRP passes resulted in the highest fatigue strength, due to the optimal surface properties including higher extent of grain refinement, larger compressive residual stresses, 'smoother' surface morphology and increased micro-hardness. However, the effect of USRP technology on improving fatigue strength of TB8 alloy was not significant in comparison with that of other titanium alloys(for example, Ti6 Al4 V), which was attributed to the notable surface residual stresses relaxation revealed from measurements on postfatigued USRP samples. Electron backscatter diffraction analysis confirmed that fatigue crack initiation occurred in the larger grains on the surface with high Schmid factor. Small cracks were found to propagate into the core material in a mixed transgranular and intergranular mode. Further analysis indicated that grain growth existed in post-fatigued USRP-treated TB8 samples and that the average geometrically necessary dislocations value reduced after fatigue loading. | Dan Liu Daoxin Liu Mario Guagliano Xingchen Xu Kaifa Fan Sara Bagherifard | 2021 | Journal of Materials Science & Technology2021，，2： | 5 |
| 7 | Wheat breeding history reveals synergistic selection of pleiotropic genomic sites for plant architecture and grain yield显示文摘Diversity surveys of crop germplasm are important for gaining insights into the genomic basis for plant architecture and grain yield improvement,which is still poorly understood in wheat.In this study,we exome sequenced 287 wheat accessions that were collected in the past 100 years.Population genetics analysis identified that 6.7%of the wheat genome falls within the selective sweeps between landraces and cultivars,which harbors the genes known for yield improvement.These regions were asymmetrically distributed on the A and B subgenomes with regulatory genes being favorably selected.Genome-wide association study(GWAS)identified genomic loci associated with traits for yield potential,and two underlying genes,TaARF12 encoding an auxin response factor and TaDEP1 encoding the G-proteinγ-subunit,were located and characterized to pleiotropically regulate both plant height and grain weight.Elite single-nucleotide haplotypes with increased allele frequency in cultivars relative to the landraces were identified and found to have accumulated over the course of breeding.Interestingly,we found that TaARF12 and TaDEP1 function in epistasis with the classical plant height Rht-1 locus,leading to propose a“Green Revolution”-based working model for historical wheat breeding.Collectively,our study identifies selection signatures that fine-tune the gibberellin pathway during modern wheat breeding and provides a wealth of genomic diversity resources for the wheat research community. | Aili Li Chenyang Hao Zhenyu Wang Shuaifeng Geng Meiling Jia Fang Wang Xiang Han Xingchen Kong Lingjie Yin Shu Tao Zhongyin Deng Ruyi Liao Guoliang Sun Ke Wang Xingguo Ye Chengzhi Jiao Hongfeng Lu Yun Zhou Dengcai Liu Xiangdong Fu Xueyong Zhang Long Mao | 2022 | Molecular Plant2022，15，3： | 4 |
| 8 | Coherent structures and wavepackets in subsonic transitional turbulent jets显示文摘A large eddy simulation(LES) is performed for two subsonic jets with a Reynolds number of Re = 105,which have different core temperatures, i.e., the cold and hot jet. The far-field overall sound pressure levels(OASPL)and noise spectra are well validated against previous experimental results. It is found that the OASPL is raised by heating at shallow angles. The most energetic coherent structures are extracted with specified frequencies using the filter based on the frequency domain variant of the snapshot method of proper orthogonal decomposition(POD). The m = 0, 1 modes have high coherence of near-field pressure for both jets, while the coherence of m = 0 modes is enhanced greatly by heating. Based on the coherent structures, spatial wavepackets are educed and the characteristics of growth, saturation and decay are analyzed and compared between the two jets in detail. The results show that heating would enhance the linear growth rate for high frequency components, and nonlinear growth rates for low frequency components in general, which are responsible for higher OASPL in the hot jet. The far-field sound generated by wavepackets is computed using the Kirchhoff extrapolation,which matches well with that of LES at shallow angles.This indicates that the wavepackets associated with coherent structures are dominant sound sources in forced transitional turbulent jets. Additionally, the present POD method is proven to be a robust tool to extract the salient features of the wavepackets in turbulent flows. | Haihua Yang Xingchen Zhang Lingke Ran Dejun Sun Zhenhua Wan | 2017 | Acta Mechanica Sinica2017，33，1： | 4 |
| 9 | CRISPR/Cas9:A powerful tool for crop genome editing显示文摘The CRISPR/Cas9 technology is evolved from a type II bacterial immune system and represents a new generation of targeted genome editing technology that can be applied to nearly all organisms. Site-specific modification is achieved by a single guide RNA(usually about 20nucleotides) that is complementary to a target gene or locus and is anchored by a protospaceradjacent motif. Cas9 nuclease then cleaves the targeted DNA to generate double-strand breaks(DSBs), which are subsequently repaired by non-homologous end joining(NHEJ) or homology-directed repair(HDR) mechanisms. NHEJ may introduce indels that cause frame shift mutations and hence the disruption of gene functions. When combined with double or multiplex guide RNA design, NHEJ may also introduce targeted chromosome deletions,whereas HDR can be engineered for target gene correction, gene replacement, and gene knock-in. In this review, we briefly survey the history of the CRISPR/Cas9 system invention and its genome-editing mechanism. We also describe the most recent innovation of the CRISPR/Cas9 technology, particularly the broad applications of modified Cas9 variants, and discuss the potential of this system for targeted genome editing and modification for crop improvement. | Gaoyuan Song Meiling Jia Kai Chen Xingchen Kong Bushra Khattak Chuanxiao Xie Aili Li Long Mao | 2016 | The Crop Journal2016，4，2： | 4 |
| 10 | Ni-doped ZnCo2O4 atomic layers to boost the selectivity in solar-driven reduction of CO2显示文摘 | Katong Liu Xiaodong Li Liang Liang Ju Wu Xingchen Jiao Jiaqi Xu Yongfu Sun Yi Xie | 2018 | Nano Research2018，11，6： | 3 |
| 11 | An elevated preoperative serum calcium level is a significant predictor for positive peritoneal cytology in endometrial carcinoma显示文摘Objective:To evaluate preoperative serum calcium concentration and investigate the association between calcium level and positive peritoneal cytology in endometrial carcinoma(EC).Methods:A total of 510 patients who were diagnosed with EC and had surgery were initially enrolled in this study at Peking University People's Hospital between January 2012 and December 2016.Clinical characteristics and preoperative serum calcium,albumin,carbohydrate antigen(CA)125,CA19-9,carcinoembryonic antigen(CEA)were extracted from patient records and evaluated according to postoperative peritoneal cytology.Predictive factors were assessed with Cox univariate and multivariate analyses.Factors selected from multivariate analysis results were used to build a predictive model.Results:A total of 510 patients are identified in our database and 444 patients who fulfilled inclusion and exclusion criteria are included in this study.Univariate analysis revealed that ionized calcium concentration was closely related to positive peritoneal cytology,tumor grade and lymph-vascular space invasion(LVSI).Moreover,peritoneal cytology was significantly associated with hypertension,tubal ligation,serum CA125,CA19-9,CEA and ionized calcium level.Multivariate analysis revealed that albumin-adjusted calcium level,CA125 and tubal ligation were independent predictive factors of positive peritoneal cytology(P<0.05).A combination of ionized calcium level with the other two indexes yielded significantly great area under the curve(AUC=0.824).Conclusions:This study enhanced the value of preoperative ionized calcium level.We also identified several potential biomarkers to predict positive peritoneal cytology in EC patients before surgery. | Xingchen Li Yuan Cheng Yangyang Dong Boqiang Shen Xiao Yang Jiaqi Wang Jingyi Zhou Jianliu Wang | 2019 | Chinese Journal of Cancer Research2019，31，6： | 3 |
| 12 | Storage capacity allocation strategy for distribution network with distributed photovoltaic generators显示文摘Distributed photovoltaic generators(DPGs) have been integrated into the medium/low voltage distribution network widely. Due to the randomness and fluctuation of DPG, however, the distribution and direction of power flow changed frequently some days. Therefore, more attention is needed to ensure the safe operation of the distribution network. The installation of energy storage systems(ESSs) can help the network withstand thefluctuations caused by DPG. Based on the discrete Fourier transform method, this paper presents an ESS capacity allocation strategy for the medium/low voltage distribution network with DPG. The reliability scenario models are created via Latin hypercube sampling with Cholesky decomposition and scenario reduction. Numerical results show that the proposed strategy can reduce the power flow fluctuation with less ESS capacity, and increase the penetration capacity of DPG in the distribution network while maintaining the quality of the power supply. | Bin LI Xingchen LI Xiaoqing BAI Zhineng LI | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，6： | 2 |
| 13 | New insights into eutrophication management:Importance of temperature and water residence time显示文摘Eutrophication and harmful cyanobacterial blooms threaten water resources all over the world.There is a great controversy about controlling only phosphorus or controlling both nitrogen and phosphorus in the management of lake eutrophication.The primary argument against the dual nutrients control of eutrophication is that nitrogen fixation can compensate the nitrogen deficits.Thus,it is of great necessary to study the factors that can significantly affect the nitrogen fixation.Due to the difference of climate and human influence,the water quality of different lakes(such as water temperature,N:P ratio and water residence time)is also quite different.Numerous studies have reported that the low N:P ratio can intensify the nitrogen fixation capacities.However,the effects of temperature and water residence time on the nitrogen fixation remain unclear.Thus,30 shallows freshwater lakes in the eastern plain of China were selected to measure dissolved N_(2) and Ar concentrations through N_(2):Ar method using a membrane inlet mass spectrometer to quantify the nitrogen fixation capacities and investigate whether the temperature and water residence time have a great impact on nitrogen fixation.The results have shown that the short lake water residence time can severely inhibit the nitrogen fixation capacities through inhibiting the growth of nitrogenfixing cyanobacteria,changing the N:P ratio and resuspending the solids from sediments.Similarly,lakes with low water temperature also have a low nitrogen fixation capacity,suggesting that controlling nitrogen in such lakes is feasible if the growth of cyanobacteria is limited by nitrogen. | Feng Zhao Xu Zhan Hai Xu Guangwei Zhu Wei Zou Mengyuan Zhu Lijuan Kang Yulong Guo Xingchen Zhao Zicong Wang Wei Tang | 2022 | Journal of Environmental Sciences2022，34，1： | 2 |
| 14 | Effect of hole arrangement patterns on the leakage and rotordynamic characteristics of the honeycomb seal显示文摘The honeycomb seal is a vital component to reduce the leakage flow and improvethe system stability for the turbomachines. In this work, a three-dimensional model is established for the interlaced hole honeycomb seal (IHHCS) and the non-interlaced hole honeycombseal (NIHHCS) to investigate its leakage and rotordynamic characteristics by adopting computational fluid dynamics (CFD). Results show that the hole arrangement patterns have littleimpact on the pressure drop and turbulence kinetic energy distribution for the seals, and theIHHCS possesses a slightly lower leakage flow rate than the NIHHCS. Moreover, the numericalresults also show that the NIHHCS possesses a better rotordynamic performance than theIHHCS at all investigated conditions. Both seals show a larger k and a lower Ceff with the increase of the positive preswirl ratios and rotational speeds, while the negative preswirl ratioswould reduce the k and improve the Ceff. The NIHHCS possesses a higher absolute value ofFt for all operating conditions, this could explain the distinction of Ceff for both seals atdifferent working conditions. | Wanfu Zhang Chengjing Gu Xingchen Yang Kexin Wu Chun Li | 2022 | Propulsion and Power Research2022，11，2： | 2 |
| 15 | Recent advances on the structural modification of parthenolide and its derivatives as anticancer agents显示文摘Parthenolide(PTL)is a sesquiterpene lactone derived from medicinal plant feverfew(Tanacetum parthenium).Recent studies have demonstrated that it has multiple pharmacological activities,especially in the treatment of various hematological and solid cancers.The superior anticancer activity of PTL suggests that it has the potential to be a first-line drug.However,due to the limited physical and chemical properties,as well as bioavailability,structural modification strategies are strongly recommended to improve the anticancer activity.This review describes representative PTL derivatives obtained by different modification strategies,which are reported to exert antiproliferative activities superior to the parent compound PTL.Furthermore,we also summarize their basic mechanisms on cancer-related signaling pathways,so as to explain the potential and characteristics of PTL and its derivatives in cancer therapy. | LIU Xingchen WANG Xiaobing | 2022 | Chinese Journal of Natural Medicines2022，20，11： | 2 |
| 16 | Luminescence properties and energy transfer mechanism of Er 3+ /Tm 3+ co-doped tellurite glasses显示文摘 | Xingchen Xu Yaxun Zhou Shichao Zheng Dandan Yin Xunsi Wang | 2012 | Journal of Alloys and Compounds2012，，： | 2 |
| 17 | Single-shot ultrafast multiplexed coherent diffraction imaging显示文摘Classic interferometry was commonly adopted to realize ultrafast phase imaging using pulsed lasers;however, the reference beam required makes the optical structure of the imaging system very complex, and high temporal resolution was reached by sacrificing spatial resolution. This study presents a type of single-shot ultrafast multiplexed coherent diffraction imaging technique to realize ultrafast phase imaging with both high spatial and temporal resolutions using a simple optical setup, and temporal resolution of nanosecond to femtosecond scale can be realized using lasers of different pulse durations. This technique applies a multiplexed algorithm to avoid the data division in space domain or frequency domain and greatly improves the spatial resolution. The advantages of this proposed technique on both the simple optical structure and high image quality were demonstrated by imaging the generation and evaluating the laser-induced damage and accompanying phenomenon of laser filament and shock wave at a spatial resolution better than 6.96 μm and a temporal resolution better than 10 ns. | YINGMING XU XINGCHEN PAN MINGYING SUN WENFENG LIU CHENG LIU JIANQIANG ZHU | 2022 | Photonics Research2022，10，8： | 2 |
| 18 | iRGD decorated liposomes:A novel actively penetrating topical ocular drug delivery strategy显示文摘Ocular drug delivery remains a significant challenge that is limited by poor corneal retention and permeation,resulting in low ocular bioavailability(<5%).Worse still,the most convenient and safe route of ocular drug administration,topical administration results in a drug bioavailability of less than 1%.iRGD modified drug delivery strategies have been developed for cancer therapy,however active targeting iRGD platforms for ocular drug delivery have yet to be explored.Herein,an iRGD modified liposomes was developed for ocular drug delivery via topical administration.The results indicated that iRGD modified liposomes could prolong the corneal retention time and enhance corneal permeability in an iRGD receptor mediated manner.These findings provided a novel strategy for topical ocular drug delivery for the treatment of posterior ocular diseases. | Hai Huang Xiaorong Yang Huili Li Hansi Lu James Oswald Yongmei Liu Jun Zeng Chaohui Jin Xingchen Peng Jiyan Liu Xiangrong Song | 2020 | Nano Research2020，13，11： | 2 |
| 19 | Numerical investigation on leakage and rotordynamic performance of the honeycomb seal with swirl-reverse rings显示文摘Honeycomb seals are a crucial component to restrict the leakage flow and improve system stability for the turbomachines and aero-engines.In this work,the leakage and rotordynamic performance of honeycomb seals with the Swirl-Reverse Ring(SRR)is predicted by employing the approach of Computational Fluid Dynamics(CFD)and the multifrequency whirling model theory.Numerical results show that the positive preswirl flow and circumferential velocity can be effectively weakened for the honeycomb seal as SRR is introduced.The obtained results also suggest that the direct stiffness,direct damping,and effective stiffness will not reduce,for the honeycomb seal is introduced to SRR.However,the honeycomb seal with SRR can significantly reduce the crosscoupled stiffness and remarkably enhance the effective damping.Meanwhile,the absolute value of negative tangential force acting on the rotor surface significantly increased for the honeycomb seal introduced SRR.Therefore,the whirling velocity of the rotor would be weakened.This phenomenon would be conducive to improve the stability of the rotor.Besides,the performance of SRR can be further enhanced when SRR possesses a smaller bending angle,and a higher arrangement density and height. | Chengjing GU Wanfu ZHANG Xingchen YANG Kexin WU Lu YIN | 2022 | Chinese Journal of Aeronautics2022，35，6： | 2 |
| 20 | Large-size niobium disulfide nanoflakes down to bilayers grown by sulfurization显示文摘Atomically thin layers of group VB transition metal dichalcogenides (TMDs)provide a unique platform for studying two-dimensional (2D) superconductivityand charge density waves. Thus far, the bottom-up synthesis of these 2D TMDshas often involved precursors that are corrosive or toxic, and their lateral sizesare typically only a few micrometers. In this paper, we report the growth ofNbS2 nanoflakes with a thickness down to bilayers and a lateral dimension upto tens of micrometers without using harsh chemical species. NbS2 nanoflakeseither standing or lying with respect to the sapphire substrate were obtained bysulfurization of niobium oxide films that were prepared via pulsed laser deposition.Standing nanoflakes are considered to grow epitaxiaUy on the sapphire substrateaccording to their ordered orientation, while lying nanoflakes with randomorientations were grown directly on top of the niobium oxide films. The Ramanspectra of the 3R-phase exhibit strong dependence on the layer thickness, wherethe A1 mode softens as the layer number decreases. In contrast to the stable bulkNbS2, the ultra-thin nanoflakes were oxidized on their top surfaces after prolongedexposure to air, as revealed by X-ray photoelectron spectroscopy. Our workexplores an important route to synthesize large-size NbS2 nanoflakes and studiesthe oxidation process, which is a critical factor to consider if practical applicationsshould be realized in the future. | Zhen Li Wencao Yang Yaroslav Losovyj Jun Chen Enzhi Xu Haoming Liu Madilynn Werbianskyj Herbert A. Fertig Xingchen Ye Shixiong Zhang | 2018 | Nano Research2018，11，11： | 2 |
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