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| 1 | Hypoxla inducible factor 1 (HIF-1) and cardioprotection显示文摘 | Demet TEKIN Ali D DURSUN Lei XI | 2010 | Acta Pharmacologica Sinica2010，31，9： | 62 |
| 2 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 3 | Research on Product Information Integrating and Sharing for Dynamic Colla boration显示文摘Dynamic Collaboration emerges as the new trend of n et working and collaborating work in manufacturing industry, in which product infor mation sharing among allied enterprises plays very important roles in collaborat ing product development. This thesis aims at studying the integrating, contr olling and sharing mode of product information among the heterogeneous and dispe rsed environments through Internet, and proposes the information integrating/sha ring architecture based on the Product Master Model (PMM). The following are the main contents of this thesis: 1) Research on the XML based PMM model for integration and sharing of product in formation After analyzing the requirement of the allied Enterprise for the product infor mation, the XML based product master model (XPMM) is proposed as the integrating mechanism of heterogeneous and dispersed product information. The XPMM is divid ed into some sub-models: whole-life controlling model, product defining model, conception model, design model, product structure model, machining model, q uality model, evaluating model. The character and accessing approach of XPMM is discussed in detail. 2) Research on the mapping pattern and mapping rule of STEP/XML According to feature of XML Schema and STEP EXPRESS, the memory-constructing-t ree model is put forward as STEP/XML mapping pattern, which is constructed dynam ically according to the bottom-to-top reference relationship. Based on mapping pattern, the multi-layer XML/STEP mapping rule is discussed detailed including relation mapping, entity mapping, data type mapping, reference mapping and func tion mapping. 3) Research on the Product Information Integration and Sharing (PIIS) Architectu re Based on the XPMM, the PIIS architecture is proposed. The PIIS support the local and dispersed product information to be integrated and shared on the contro l of the XPMM. The architecture is divided into three layers :Applying-Obj ect-LayerData-Integration-Layer and STEP-Data-Layer. The kernel of the PI IS Architecture is this Data-Integration-Layer, which control the whole proces s of XPMM creating, the data approaching. The function and structure of every la yer is discussed too. | HE Wen-rui, QIN Zhong-bao, Qin Ji-feng, HE Wei-ping (Education Ministry Key Laboratory of Contemporary Design and Integrate d Manufacturing Technology, Northwestern Polytechnical University, Xi’an 710072, China) | 2002 | 厦门大学学报(自然科学版)2002，41，S1： | 4 |
| 4 | Surface characterization of steel/steel contact lubricated by PA06 with novel black phosphorus nanocomposites显示文摘In the present work,two types of novel nano additives,titanium sulfonate ligand/black phosphorus(TiLi/BP)and titanium dioxide/black phosphorus(TiCVBP)nanocomposites,were prepared.The tribological behavior of the steel/steel friction pairs lubricated by polyalphaolefins type 6(PA06)containing the nanocomposites under boundary lubrication was studied.The worn surfaces were analyzed using modem surface techniques.The experimental results show that the rubbed surfaces became smooth and showed little wear with the addition of the nanocomposites.TiO_(2)/BP nanocomposites can significantly improve the lubricity of BP nanosheets under high contact stress.The synergistic roles of the load-bearing abilities and rolling effect of TiO_(2) nanoparticles,the slip induced by the BP with its layered structure,and the establishment of a tribofilm on the sliding interface are the basis of the tribological mechanisms. | Zhiheng LUO Jingyuan YU Yufu XU He XI Gang CHENG Lulu YAO Ruhong SONG Karl D DEARN | 2021 | Friction2021，9，4： | 2 |
| 5 | Impact of virus genotype on interferon treatment of patients with chronic hepatitis C: a multicenter controlled study显示文摘BACKGROUND: Some factors have been reported to besassociated with a greater likelihood of sustained viral re-sponse ( SVR) in the interferon (IFN) treatment of chronichepatitis C. The factors include HCV genotype, HCVRNA level in serum, state of liver disease, baseline bodyweight, age, sex, and race. The aim of this trial was to in-vestigate the influence of HCV genotype on the IFN treat-ment of patients with chronic hepatitis C.METHODS: The genotypes of HCV virus were determinedin the patients with chronic hepatitis C from several hospi-tals of China enrolled into the randomized, opened andcontrolled trial of Peg-IFN alpha-2a (pegasys) treatment,controlled with IFN-α-2a (roferon-A). The serum ALTlevels and HCV RNA concentrations of the patients weredetected before and at the end of treatment and during thefollow-up. The influence of HCV genotype on the IFNtreatment of patients with chronic hepatitis C was analyzedin intention-to-treat (ITT) population.RESULTS: The HCV genotypes of 202 patients were deter-mined. Of these patients, 158(78.22%) were infected withgenotype 1 HCV and 44(21.78%) with genotype non-1.The viral response at the end of treatment (ETVR) andsustained viral response (SVR) rates were 53.80% and25.32% respectively in patients with genotype 1 HCV, butthey were 61.36% and 43.18% in patients with genotypenon-1. The difference of SVR between patients with geno-type 1 HCV and those with genotype non-1 was significant(P =0.021). After being grouped by the used drugs, theETVR rates of patients infected with genotype 1 and non-1HCV were 76.83% and 80.95% in the patients treated withpegasys (P =0.686); but their SVR rates were 35.37% and66.67% (P =0. 01). The viral relapse rate of genotype 1HCV (55.56%) was significantly higher than that of geno-type non-1 HCV (23.53%) (P=0.02). In roferon-A group,the ETVR and SVR rates of patients with genotype 1 HCVwere 28.95% and 14.47% respectively, which were lowerbut not more significant than those of patients with geno-type non-1 HCV (43.48% and 21.74%). Moreover, the vi-ral relapse rate of genotype 1 HCV (72.73%) was higherbut not more significant than that of genotype non-1 HCV(50.00%) (P=0.21).CONCLUSION: HCV genotype could affect the efficacies,mainly sustained responses, of IFN treatment in patientswith chronic hepatitis C, and the effects of IFN are relatedto drugs and therapeutic course. | Yao Xie, Dao-Zhen Xu, Zhi-Meng Lu, Kang-Xian Luo, Ji-Dong Jia, Yu-Ming Wang,Gui-Zhen Zhao, Shu-Lin Zhang and Da-Zhi Zhang Department of Infeetious Diseases , Beijing Ditan Hos-pital, Beijing 100011 , China Department of Infec-tious Diseases, Ruijin Hospital, Shanghai 200025, China De-partment of Infectious Diseases, Naifang Hospital, First Military Medical U-niversity, Guangzhou 510515, China (Luo KX) Center of Liver Disease,Beijing Friendship Hospital, Beijing 100050, China (Jia J D ) Institute ofInfectious Disease, Southwest Hospital, Third Military Medical University,Chongqing 410032, China Department of Infectious Disea-ses, Second Hospital, China Medical University, Shenyang 110004, China Department of Infectious Diseases, First Hospital, Xi’ an Jiao-tong University, Xi’ an 710061 , China ) Liver Disease Centerof Chongqing, Second Hospital, Chongqing Medical University,Chongqing 410010, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，3： | 2 |
| 6 | Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies显示文摘 | Lehmann Brian D Bauer Joshua A Chen Xi Sanders Melinda E Chakravarthy A Bapsi Shyr Yu Pietenpol Jennifer A | 2011 | Journal of Clinical Investigation2011，，7： | 2 |
| 7 | Contributing to local policymaking on GHG emission reduction through inventoryingand attribution: A case study of Shenyang, China 显示文摘 | Xi F M Geng Y Chen X D | 2011 | Energy Policy2011，39，2011： | 1 |
| 8 | Experimental investigation on the breakage of hard rock by the PDC cutters with combined action modes 显示文摘 | LI Xi -bing Summers D A Rupert G | 2001 | Tunnelling and Underground Space Technology2001，16，： | 1 |
| 9 | The condensin complexis essential for amitotic segregation of bulk chromosomes,but notnucleoli,in the ciliate Tetrahymena thermophila 显示文摘 | Cervantes M D Coyne R S Xi X | 2006 | Mol CellBiol2006，26，12： | 1 |
| 10 | 显示文摘 | CHENG L ZHANG X M XI X D | 1996 | J Electronanal Chem1996，407，： | 1 |
| 11 | Fluorescence excitation- emission matrix spectroscopy with regional integration analysis for characterizing composition and transformation of dissolved organic matter in landfill leachates 显示文摘 | HE X S XI B D WEI Z M | 2011 | Journal of Hazardous Materials2011，190，123： | 1 |
| 12 | Electron cyclotron wave current startup for ohmic discharges on the CT-6B tokamak 显示文摘 | Yao XI Jiang D Feng c | 2000 | Plasma Science IEEE Transactions on2000，28，1： | 1 |
| 13 | Investigation into the penetration and impact resistance of PDC cutters inclined at different attack angles显示文摘 | LI Xi - bing Summers D A Rupert G | 2001 | Transation of Nonferrous Metals Society of China2001，10，2： | 1 |
| 14 | Hypoxia inducible factor 1 ( HIF - 1 ) and cardioprotection 显示文摘 | Tekin D Dursun AD Xi L | 2010 | Acta Pharmacol Sin2010，31，9： | 1 |
| 15 | Prevalence of metabolic syndrome and its influencing factors among the Chinese adults:the China Health and Nutrition Survey in 2009 显示文摘 | Xi B He D Hu Y | 2013 | Prey Med2013，57，： | 1 |
| 16 | Wave propagation analysis of porous rocks with the thermal activated relaxation mechanism显示文摘 | XI D XU S DU Y | 2011 | Journal of Applied Geophysics2011，73，3： | 1 |
| 17 | Structure of organoclays-an X-ray diffraction and thermogravimetric analysis study 显示文摘 | Xi Y F Zhe D He H P | 2004 | J Colloid Interface Sci2004，277，： | 1 |
| 18 | The effects of neutron irradiation on the oxygen precipitation in Czochralski-silicon, 显示文摘 | LI Y XI GUO H Y LIU B D LIU T J HAO Q Y LIU C C YANG D R QUE D L | 2003 | J Cryst Growth2003，253，： | 1 |
| 19 | Spintronic memristor through spin-torque-induced magnetization motion 显示文摘 | Wang X Chen Y Xi H Dimitrov D | 2009 | IEEE Electron Device Letters (S0741-3106)2009，30，3： | 1 |
| 20 | Damage boundary of a packaging system under rectangular pulse excitation显示文摘 | Wang Z W Wu C F Xi D C | 1998 | Packaging Technology and Science1998，11，4： | 1 |
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