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| 1 | Outcome of patients with acute, necrotizing pancreatitis requiring drainage-does drainage size matter?显示文摘AIM:To assess the outcome of patients with acute necrotizing pancreatitis treated by percutaneous drainage with special focus on the influence of drainage size and number. METHODS:We performed a retrospective analysis of 80 patients with acute pancreatitis requiring percutaneous drainage therapy for infected necroses. Endpoints were mortality and length of hospital stay. The influence of drainage characteristics such as the median drainage size, the largest drainage size per patient and the total drainage plane per patient on patient outcome was evaluated. RESULTS:Total hospital survival was 66%. Thirty-four patients out of all 80 patients (43%) survived acute necrotizing pancreatitis with percutaneous drainage therapy only. Eighteen patients out of all 80 patients needed additional percutaneous necrosectomy (23%). Ten out of these patients required surgical necrosectomy in addition, 6 patients received open necrosectomy without prior percutaneous necrosectomy. Elective surgery was performed in 3 patients receiving cholecystectomy and one patient receiving resection of the parathyroid gland. The number of drainages ranged from one to fourteen per patient. The drainage diameter ranged from 8 French catheters to 24 French catheters. The median drainage size as well as the largest drainage size used per patient and the total drainage area used per patient did not show statistically significant influence on mortality. CONCLUSION:Percutaneous drainage therapy is an effective tool for treatment of necrotizing pancreatitis.Large bore drainages did not prove to be more effective in controlling the septic focus. | T Bruennler J Langgartner S Lang CE Wrede F Klebl S Zierhut S Siebig F Mandraka F Rockmann B Salzberger S Feuerbach J Schoelmerich OW Hamer | 2008 | World Journal of Gastroenterology2008，14，5： | 23 |
| 2 | Recovery from respiratory failure after decompression laparotomy for severe acute pancreatitis显示文摘We present three cases of patients (at the age of 56 years, 49 years and 74 years respectively) with severe acute pancreatitis (SAP), complicated by intra-abdominal compartment syndrome (ACS) and respiratory insufficiency with limitations of mechanical ventilation. The respiratory situation of the patients was significantly improved after decompression laparotomy (DL) and lung protective ventilation was re-achieved. ACS was discussed followed by a short review of the literature. Our cases show that DL may help patients with SAP to recover from severe respiratory failure. | Sylvia Siebig Igors Iesalnieks Tanja Bruennler Christine Dierkes Julia Langgartner Juergen Schoelmerich Christian E Wrede | 2008 | World Journal of Gastroenterology2008，14，35： | 7 |
| 3 | Local hypothermia and optimal temperature for stroke therapy in rats显示文摘冷盐溶液的 intravascular 注入有效地导致的背景本地降低体温在中风减少大脑损坏。我们进一步在我们的学习决定了本地降低体温的最佳的温度。78 只成年男 Sprague Dawley 老鼠(260-300 g ) 随机被划分成 3 个组的方法:组 A,没有冷盐的注入(n=-26 )( 控制组) 的 ischemia/reperfusion;组 B,注入与 20 在灌注(n=26 ) 前盐;组织 C:有在灌注(n=26 ) 前盐的 10 ~ C 的注入。在每个组,我们选择了 15 只老鼠因为监视物理索引和大脑(外皮和 striatum ) 和身体(肛门) 的温度,大脑梗塞体积的测量,对神经病学的赤字的评价和幸存在 48 个小时灌注评价。从各个的 8 只老鼠组织的另外一个为在灌注以后在 48 个小时检验大脑浮肿, 3 由电子显微镜学(他们) 为组织学的观察从各个组织的另外一个和轻显微镜学(LM ) 被选择。在那里的结果不在考试期间是在为物理索引的 3 个组之中的重要差别(F (2,45 )=0.577, P=0.568;F (2, 45 )= 0.42,为血压的 P=0.78 和血气体分析,分别地) 。大脑温度显著地与另外的组相比在组 C 被减少(F (2, 45 )=37.074, P=0.000;F (2, 45 )=32.983, P=0.000 外皮和 striatum 温度分别地) 当在在在灌注以后的组 A 和 B 或 C 之间的直肠的温度的差别不是重要的时(F (2, 45 )= 0.17115, P=0.637 ) 。并且大脑梗塞体积显著地在组 C 被减少(从 40%?? 獲有 ?? ″ ?栠灡潬祴数 | WU Hao JIANG Li-dan Karsten H. Wrede JI Xun-ming ZHAO Xi-qing TIAN Xin GAO Yu-fei LING Feng | 2009 | Chinese Medical Journal2009，，13： | 5 |
| 4 | Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic ac id synthesis in the pancreatic β cell line INS-1显示文摘 | Cousin SP Nugl SR Wrede CE | | 0，，01： | 1 |
| 5 | A saliency map based on sampling an image into random rectangular regions of interest 显示文摘 | Vikram T N Tscherepanow M Wrede B | 2012 | Pattern Recognition2012，45，9： | 1 |
| 6 | Free fatty acid-in-duced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic β-cells line INS-1 显示文摘 | Cosion SP Hugl SR Wrede CE | 2001 | Endocrinology2001，142，1： | 1 |
| 7 | Transcranial direct current stimulation induces polarity-specific changes of cortical blood perfusion in the rat显示文摘 | Dorothee Wachter Arne Wrede Walter Schulz-Schaeffer Ali Taghizadeh-Waghefi Michael A. Nitsche Anna Kutschenko Veit Rohde David Liebetanz | 2010 | Experimental Neurology2010，，2： | 1 |
| 8 | A saliency map based on sampling an image into random rectangular regions of interest显示文摘 | VIKRAM T N TSCHEREPANOW M WREDE B | 2012 | Pattern Recognition2012，45，9： | 1 |
| 9 | Enhanced fault ride-through method for wind farms connected to the grid through VSC-based HVDC transmission显示文摘 | FeltesC Wrede H Friedrich WK | 2009 | IEEE Trans on Power Systems2009，24，3： | 1 |
| 10 | Enhanced fault ride through method for wind farms connected to the grid through VSC-based HVDC transmission 显示文摘 | FELTES C WREDE H KOCH F W | 2009 | IEEE Trans on Power Systems2009，24，3： | 1 |
| 11 | Reducing the excess burden of subsidizing the stork: joint taxation, individual taxation, and family tax splitting显示文摘 | Volker Meier Matthias Wrede | 2013 | Journal of Population Economics2013，，3： | 1 |
| 12 | A randomized clinical trialcomparing the impact of different oral hygiene protocols andsealant applications on plaque, gingival, and caries index scores显示文摘 | Zingler S Pritsch M Wrede DJ | 2014 | Eur J Orthod2014，36，2： | 1 |
| 13 | Free fatty acid-in-duced inhibition of glucose and insulin-like growth factor Iinduced deoxyribonucleic acid synthesis in the pancreatic β-cell line INS-1 显示文摘 | Cousin S P Hugl S R Wrede C E | 2001 | Endocrinology2001，142，： | 1 |
| 14 | Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis,which can be compensated for by introduction of IRS-4 expression显示文摘 | Lingohr MK Dickson LM Wrede CE | 2003 | Mol Cell Endocrinol2003，209，12： | 1 |
| 15 | Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta -cells (INS-1)显示文摘 | Wrede CE Dickson LM Lingohr MK | 2002 | J Biol Chem2002，277，49： | 1 |
| 16 | Enhanced fault ride-through method for wind farms connected to the grid through VSC-based HVDC transmission显示文摘 | Felts C Wrede H Koch F W | 2009 | IEEE Trans on Power Systems2009，24，3： | 1 |
| 17 | Commuting subsidies with two transport modes显示文摘 | Rainald Borck Matthias Wrede | | 0，，63： | 1 |
| 18 | Fluorescence in situ hybridization investigation of cutaneous lesions in acute promyelocytic leukemia显示文摘 | Wrede JE Sundram U Kohler S | 2005 | Mod Pathol2005，18，12： | 1 |
| 19 | Direct posterior reduction and fixa- tion for the treatment of basilar invagination with atlantoaxial dislocation 显示文摘 | Jian FZ Chen Z Wrede KH | 2010 | Neurosurgery2010，66，4： | 1 |
| 20 | Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta cell line INS-I显示文摘 | Cousin SP Hagl 8R Wrede CE | 2001 | Fndocrinol oKy2001，142，： | 1 |
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