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| 1 | N-terminal truncated RHT-1 proteins generated by translational reinitiation cause semi-dwarfing of wheat Green Revolution alleles显示文摘The unprecedented wheat yield increases during the Green Revolution were achieved through the introduc-tion of the Reduced height(Rht)-B1b and Rht-D1b semi-dwarfing alleles.These Rht-1 alleles encode growth-repressing DELLA genes containing a stop codon within their open reading frame that confers gibberellin(GA)-insensitive semi-dwarfism.In this study,we successfully took the hurdle of detecting wild-type RHT-1 proteins in different wheat organs and confirmed their degradation in response to GAs.We further demonstrated that Rht-B1b and Rht-D1b produce N-terminal truncated proteins through trans-lational reinitiation.Expression of these N-terminal truncated proteins in transgenic lines and in Rht-D1c,an allele containing multiple Rht-D1b copies,demonstrated their ability to cause strong dwarfism,resulting from their insensitivity to GA-mediated degradation.N-terminal truncated proteins were detected in spikes and nodes,but not in the aleurone layers.Since Rht-B 1b and Rht-D1b alleles cause dwarfism but have wild-type dormancy,this finding suggests that tissue-specific differences in translational reinitiation may explain why the Rht-1 alleles reduce plant height without affecting dormancy.Taken together,our findings not only reveal the molecular mechanism underlying the Green Revolution but also demonstrate that trans-lational reinitiation in the main open reading frame occurs in plants. | Karel Van De Velde Stephen GThomas Floor Heyse Rim Kaspar Dominique Van Der Straeten Antje Rohde | 2021 | Molecular Plant2021，14，4： | 8 |
| 2 | 农药溶剂的评述显示文摘十九世纪末,烃类溶剂和石油产品已开始用于农药。早期,它们被用作杀虫剂;稍后二十世纪初,煤油和其他一些石油馏份开始用于对杂草防除的研究;1925年到1935年,石油产品不仅用作活性组份,也开始用作杀虫剂和杀菌剂的载体;大约在1940年,溶剂和石油制品广泛商业化地用作除草剂;二次世界大战后,溶剂和石油制品的使用得以迅猛发展。今天,溶剂选用范围已包括醇、酮及酯类等。 | M. R. Krenek W. H. Rohde 柳庆先 | 1991 | 农药译丛1991，13，5： | 4 |
| 3 | Antifibrogenic effects of vitamin D derivatives on mouse pancreatic stellate cells显示文摘AIM To study the molecular effects of three different D-vitamins, vitamin D2, vitamin D3 and calcipotriol, in pancreatic stellate cells(PSCs).METHODS Quiescent PSCs were isolated from mouse pancreas and activated in vitro by seeding on plastic surfaces. The cells were exposed to D-vitamins as primary cultures(early-activated PSCs) and upon re-culturing(fullyactivated cells). Exhibition of vitamin A-containing lipid droplets was visualized by oil-red staining. Expression of α-smooth muscle actin(α-SMA), a marker of PSC activation, was monitored by immunofluorescence and immunoblot analysis. The rate of DNA synthesis was quantified by 5-bromo-2'-deoxyuridine(Brd U) incorporation assays. Real-time PCR was employed to monitor gene expression, and protein levels of interleukin-6(IL-6) were measured by ELISA. Uptake of proline was determined using 18 F-proline.RESULTS Sustained culture of originally quiescent PSCs inducedcell proliferation, loss of lipid droplets and exhibition of stress fibers, indicating cell activation. When added to PSCs in primary culture, all three D-vitamins diminished expression of α-SMA(to 32%-39% of the level of control cells; P < 0.05) and increased the storage of lipids(scores from 1.97-2.15 on a scale from 0-3; controls: 1.49; P < 0.05). No such effects were observed when D-vitamins were added to fully-activated cells, while incorporation of Brd U remained unaffected under both experimental conditions. Treatment of re-cultured PSCs with D-vitamins was associated with lower expression of IL-6(-42% to-49%; P < 0.05; also confirmed at the protein level) and increased expression of the vitamin D receptor gene(209%-321% vs controls; P < 0.05). There was no effect of D-vitamins on the expression of transforming growth factor-β1 and collagen type 1(chain α1). The lowest uptake of proline, a main component of collagen, was observed in calcipotriol-treated PSCs.CONCLUSION The three D-vitamins inhibit, with similar efficiencies, activation of PSCs in vitro, but cannot reverse the phenotype once the cells are fully activated. | Peter Wallbaum Sarah Rohde Luise Ehlers Falko Lange Alexander Hohn Carina Bergner Sarah Marie Schwarzenbock Bernd Joachim Krause Robert Jaster | 2018 | World Journal of Gastroenterology2018，24，2： | 3 |
| 4 | Fatal Outcome of Lung Transplantation in Cystic Fibrosis Patients due to Small-Colony Variants of the Burkholderia cepacia Complex显示文摘 | S. H?u?ler C. Lehmann C. Breselge M. Rohde M. Cla?en B. Tümmler P. Vandamme I. Steinmetz | 2003 | European Journal of Clinical Microbiology & Infectious Diseases2003，，4： | 2 |
| 5 | EVA弹性体在工业橡胶制品中的应用显示文摘1 前言乙烯醋酸乙烯酯橡胶由乙烯醋酸乙烯酯共聚物链段组成,其中醋酸乙烯酯含量在40%~80%(重量)之间。达到最佳工艺时其门尼粘度ML_(1+4)/100℃为20~35,这与易加工的丁腈类橡胶粘度水平相当。醋酸乙烯酯含量决定了它几乎或完全是非晶态的,玻璃化温度约为-35℃,中等耐油性。与此相反,低醋酸乙烯酯含量的共聚物是热塑性的,由于乙烯链段的存在具有一定的结晶度。醋酸乙烯酯含量高于80%的共聚物为非晶态,但有较高的玻璃化温度和一定的热塑性。 | Ernst Rohde Bayer AG 辜晓乐 | 1993 | 橡胶参考资料1993，23，11： | 2 |
| 6 | β-联碳酰基类衍生物有序自组装膜的STM研究显示文摘在大气条件下,利用扫描隧道显微镜研究了四个β-联碳酰基类衍生物在高定向裂解石墨(HOPG)表面的自组装结构.研究分子的结构中均包含π电子共轭体系和烷基链.实验研究了分子结构对自组装结构的影响,并利用分子结构的变化实现了自组装膜结构的调控.结果表明,在甲苯溶剂中制备的这些自组装结构均长程有序,分子间氢键和偶极相互作用是影响自组装膜结构变化的重要因素. | 刁玉霞 Dirk Rohde 万立骏 | 2006 | 物理化学学报2006，22，6： | 2 |
| 7 | Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague 显示文摘 | Airhart C L Rohde H N Bohach G A | 2008 | Microbiology2008，154，7： | 1 |
| 8 | Three-dimensional rotational angiography guidance for aneurysm surgery 显示文摘 | Raabe A Beck J Rohde S | 2006 | J Neurosurg2006，105，3： | 1 |
| 9 | Decrease in prostate cancer incidence and mortality in Germany-effects of opportunistic PSA screening or more显示文摘 | Rohde V Weidner W Katalinic A | 2009 | Urol lnt2009，83，2： | 1 |
| 10 | Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22:linkage analysis in German breast cancer families显示文摘 | Seitz S Rohde K Bender E | 1997 | Oncogene1997，14，6： | 1 |
| 11 | On the origin of the human influenza virus subtypes H2N2 and H3N2显示文摘 | Scholtissek C Rohde W Von Hoyningen V | 1978 | Virology1978，87，1： | 1 |
| 12 | Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution显示文摘 | Rohde CB Zeng F Gonzalez-Rubio R | 2007 | Proc Natl Acad Sei USA2007，104，13： | 1 |
| 13 | Complications of burr- hole craniostomy and closed-system drainage for chron- ic subdural hematomas: a retrospective analysis of 376 patients显示文摘 | Rohde V Graf G Hassler W | 2002 | Neurosurg Rev2002，25，12： | 1 |
| 14 | Type IIIsecretion effectors of the IpaH family are E3 ubiquitinligases 显示文摘 | Rohde J R Breitkreutz A Chenal A | 2007 | Cell Host Microbe2007，1，1： | 1 |
| 15 | Non-encapsulated strains reveal novel insights in invasion and survival of Streptococcus suis in epithelial cells显示文摘 | BENGA L GOETHE R ROHDE M | 2004 | Cellular Microbiology2004，9，： | 1 |
| 16 | Levosimendan in acute de- compensated heart failure: systematic review and meta-analysis显示文摘 | Ribeiro RA Rohde LE Polanczyk CA | 2010 | Arq Bras Cardiol2010，95，2： | 1 |
| 17 | Structural analysis of the Waxy lus from Hordeum vulgare显示文摘 | Rohde W Becker D Salamini F | 1988 | Nucleic Acids Research1988，，： | 1 |
| 18 | High-and low-level dissonance-based eating disorder prevention programs with young women with body image concerns:an experimental trial显示文摘 | McMil an W Sitce E Rohde P | | 0，，01： | 1 |
| 19 | Rapid metagenomic diagnostics for suspected outbreak of severe pneumonia 显示文摘 | Fischer N Rohde H Indenbirken D | 2014 | Emerg Infect Dis2014，20，6： | 1 |
| 20 | The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions显示文摘 | DAUGAARD M ROHDE M J))TTEL)M | 2007 | FEBS Lett2007，581，19： | 1 |
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