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37篇 您的检索式：作者名="Wrede CE"

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	题名	作者	年代	出处	被引量
1	Outcome of patients with acute, necrotizing pancreatitis requiring drainage-does drainage size matter?显示文摘AIM:To assess the outcome of patients with acute necrotizing pancreatitis treated by percutaneous drainage with special focus on the influence of drainage size and number. METHODS:We performed a retrospective analysis of 80 patients with acute pancreatitis requiring percutaneous drainage therapy for infected necroses. Endpoints were mortality and length of hospital stay. The influence of drainage characteristics such as the median drainage size, the largest drainage size per patient and the total drainage plane per patient on patient outcome was evaluated. RESULTS:Total hospital survival was 66%. Thirty-four patients out of all 80 patients (43%) survived acute necrotizing pancreatitis with percutaneous drainage therapy only. Eighteen patients out of all 80 patients needed additional percutaneous necrosectomy (23%). Ten out of these patients required surgical necrosectomy in addition, 6 patients received open necrosectomy without prior percutaneous necrosectomy. Elective surgery was performed in 3 patients receiving cholecystectomy and one patient receiving resection of the parathyroid gland. The number of drainages ranged from one to fourteen per patient. The drainage diameter ranged from 8 French catheters to 24 French catheters. The median drainage size as well as the largest drainage size used per patient and the total drainage area used per patient did not show statistically significant influence on mortality. CONCLUSION:Percutaneous drainage therapy is an effective tool for treatment of necrotizing pancreatitis.Large bore drainages did not prove to be more effective in controlling the septic focus.	T Bruennler J Langgartner S Lang CE Wrede F Klebl S Zierhut S Siebig F Mandraka F Rockmann B Salzberger S Feuerbach J Schoelmerich OW Hamer	2008	World Journal of Gastroenterology2008，14，5：	23
2	Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic ac id synthesis in the pancreatic β cell line INS-1显示文摘	Cousin SP Nugl SR Wrede CE		0，，01：	1
3	Free fatty acid-in-duced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic β-cells line INS-1 显示文摘	Cosion SP Hugl SR Wrede CE	2001	Endocrinology2001，142，1：	1
4	Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis,which can be compensated for by introduction of IRS-4 expression显示文摘	Lingohr MK Dickson LM Wrede CE	2003	Mol Cell Endocrinol2003，209，12：	1
5	Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta -cells (INS-1)显示文摘	Wrede CE Dickson LM Lingohr MK	2002	J Biol Chem2002，277，49：	1
6	Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta cell line INS-I显示文摘	Cousin SP Hagl 8R Wrede CE	2001	Fndocrinol oKy2001，142，：	1
7	Endocrine regulation in critically ill patients显示文摘	Wrede CE	2010	Dtsch Med Wochenschr2010，135，14：	1
8	Free fatty acid-induced inhibition of glucose and insulin-like growth factor Ⅰ-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1显示文摘	Cousin SP Hugl SR Wrede CE	2001	Endocrinology2001，142，1：	1
9	Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1)显示文摘	Wrede CE Dickson LM Lingohr MK	2002	J Biol Chem2002，277，49：	1
10	Fatty acid and phorbolester- mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta- cells (INS - 1 ) 显示文摘	Wrede CE Dickson LM Lingohr MK	2003	J Mol Endocrinol2003，30，3：	1
11	Free fatty acid-induced inhibition of glucb-se and insulin-like growth factor Ⅰ- induced danxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1 显示文摘	Cousin SP Hugl SR Wrede CE	2001	Endocrinology2001，，142：	1
12	Free fatty acid induced inhi-bition of glueose and insulin-like growth factor-1 induced deoxyri-bonucleic acid synthesis in the pancreatic beta-cell line INS-1显示文摘	Cousin SP Hugl SR Wrede CE	2001	Endoerinology2001，142，1：	1
13	Endocrine regulation in critically ill patients显示文摘	Wrede CE	2010	Dtsch Med Wochenschr2010，135，14：	1
14	Association between serum/erritin and the insulin resistance syndrome in a representative population显示文摘	Wrede CE Buettner R Bollheimer LC	2006	Eur J Endocrinol2006，154，2：	1
15	Protein kinase B/Akt prevents fat- ty acid-induced apoptosis in pancreatic beta-cells(INS-l)显示文摘	Wrede CE Dickson LM	2002	J Biol Chem2002，277，49：	1
16	Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isforms in pancreatic beta-cells(INS-1)显示文摘	Wrede CE Dickson LM Lingohr MK	2003	J Mol Endocrinol2003，30，3：	1
17	Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells ( INS-1 ) 显示文摘	Wrede CE Dickson LM Lingohr MK	2002	J Biol Chem2002，277，49：	1
18	Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1)显示文摘	Wrede CE Dickson LM Lingohr MK		0，，51：	1
19	Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1显示文摘	Cousin SP Hugl SR Wrede CE	2001	Endocrinology2001，142，1：	1
20	Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1)显示文摘	Wrede CE Dickson LM Lingohr MK	2003	J Mol Endocrinol2003，30，：	1

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