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| 1 | Transjugular intrahepatic portosystemic shunts and portal hypertension-related complications显示文摘Portal hypertension(PH)plays an important role in the natural history of cirrhosis,and is associated with several clinical consequences.The introduction of transjugular intrahepatic portosystemic shunts(TIPS)in the 1980s has been regarded as a major technical advance in the management of the PH-related complications.At present,polytetrafluoroethylene-covered stents are the preferred option over traditional bare metal stents.TIPS is currently indicated as a salvage therapy in patients with bleeding esophageal varices who fail standard treatment.Recently,applying TIPS early(within 72 h after admission)has been shown to be an effective and life-saving treatment in those with high-risk variceal bleeding.In addition,TIPS is recommended as the second-line treatment for secondary prophylaxis.For bleeding gastric varices,applying TIPS was able to achieve hemostasis in more than 90%of patients.More trials are needed to clarify the efficacy of TIPS compared with other treatment modalities,including cyanoacrylate injection and balloon retrograde transvenous obliteration of gastric varices.TIPS should also be considered in bleeding ectopic varices and refractory portal hypertensive gastropathy.In patients with refractory ascites,there is growing evidence that TIPS not only results in better control of ascites,but also improves long-term survivalin appropriately selected candidates.In addition,TIPS is a promising treatment for refractory hepatic hydrothorax.However,the role of TIPS in the treatment of hepatorenal and hepatopulmonary syndrome is not well defined.The advantage of TIPS is offset by a risk of developing hepatic encephalopathy,the most relevant postprocedural complication.Emerging data are addressing the determination the optimal time and patient selection for TIPS placement aiming at improving long-term treatment outcome.This review is aimed at summarizing the published data regarding the application of TIPS in the management of complications related to PH. | Sith Siramolpiwat | 2014 | World Journal of Gastroenterology2014，20，45： | 41 |
| 2 | 彩色多普勒超声对经颈静脉肝内门体分流术后支架功能障碍的诊断价值显示文摘目的探讨彩色多普勒超声诊断经颈静脉肝内门体静脉分流术(TIPS)后支架功能障碍的临床价值。方法 33例门静脉高压患者,接受TIPS治疗,术后临床怀疑支架功能障碍35例次。超声检测其门静脉主干内径、血流速度以及支架内血流速度,计算充血指数,并与DSA诊断结果对比。结果与DSA比较,超声诊断支架功能障碍符合率为100%,诊断支架狭窄和闭塞符合率为89.5%、93.8%。门静脉左支矢状部内血流方向,支架通畅时,60.0%出现离肝血流,而支架功能障碍时出现离肝血流为5.7%。支架功能障碍时,门静脉流速(26.02±8.49)cm/s,内径(1.49±0.10)cm,血流量(1563.38±529.82)ml/min,充血指数0.14±0.08;与支架通畅时比较,其上述指标均上升(P<0.05)。结论彩色多普勒超声诊断TIPS支架功能障碍具有较高的准确性,可作为TIPS术后随访的首选方法。 | 韩浩 杨建 诸葛宇征 金志斌 吴敏 | 2015 | 临床超声医学杂志2015，17，8： | 16 |
| 3 | TIPS术后分流道失效影响因素的多因素回归分析显示文摘目的分析肝硬化患者行经颈静脉肝内门体分流术(TIPS)术后分流道失效的影响因素。方法搜集2008年3月至2014年12月在本院行TIPS术(采用Fluency覆膜支架)的肝硬化患者,术后3年内发生分流道失效的30例为病例组,术后3年未发生分流道失效的30例为对照组(通过门静脉彩色多普勒超声检查及门静脉造影确定分流道是否失效),对两组病例资料进行回顾性对照研究。先对肝功能Child-Pugh评分、支架形态、术后抗凝药物使用情况等20项术前、术中及术后相关因素进行单因素分析,再将单因素分析中具有统计学差异的相关因素进行Logistic多因素回归分析。结果对20项相关因素进行单因素分析后发现两组患者在否合并门静脉血栓(癌栓)、支架形态及术中是否行曲张静脉栓塞等3项之间的差异有统计学意义(P<0.05),再将上述3项相关因素进行Logistic多因素回归分析,显示支架放置后的支架形态及术中是否进行曲张静脉栓塞与TIPS术后分流道失效有关(P<0.05)。结论支架形态不良(包括扭曲折角、支架两端盖帽)为TIPS术后分流道失效的独立危险因素(OR值为4.244),而术中曲张静脉栓塞是TIPS术后分流道失效的保护因素(OR值为0.131)。 | 马富权 李培杰 李伟之 刘梦莹 米琛 薛挥 | 2016 | 临床放射学杂志2016，35，9： | 13 |
| 4 | 彩色多普勒超声在经颈静脉肝内门体分流术联合食管胃底曲张静脉栓塞术后随访中的应用显示文摘目的探讨彩色多普勒超声在经颈静脉肝内门体分流术(TIPS)联合食管胃底曲张静脉栓塞术(SEVE)术后随访中的应用价值。方法选择2012年5月至2016年6月收治的20例肝硬化门静脉高压患者,均行TIPS联合SEVE,超声于术前及术后1周,1、6和12个月测量门静脉内径、最大流速及脾静脉流速,于术后测量支架内血流速度,术后随访时间为12个月。结果 20例患者术后随访期间无一例死亡,生存率为100%;发生肝性脑病1例;支架狭窄及闭塞各1例。术后各时间点门静脉内径无明显变化(P均>0.05),门静脉血流速度较术前显著增加(P均<0.05),6个月以后各时间点门静脉血流速度较之前呈下降改变(P均<0.05),并维持相对稳定。术分流道支架血流速度术后1周及3、6个月相互比较无明显差异(P均>0.05),6个月以后各时间点血流速度较之前呈下降改变(P均<0.05),并维持相对稳定。结论彩色多普勒超声可以有效方便地检测术后支架和门静脉内血流速度,是TIPS术前检查及术后随访的重要方法。 | 王艳华 王涌臻 | 2017 | 中国临床研究2017，30，9： | 12 |
| 5 | Transjugular intrahepatic portosystemic shunt with covered stents for hepatocellular carcinoma with portal vein tumor thrombosis显示文摘AIM: To evaluate transjugular intrahepatic portosystemic shunt(TIPS) with covered stents for hepatocellular carcinoma(HCC) with main portal vein tumor thrombus(PVTT). METHODS: Eleven advanced HCC patients(all male, aged 37-78 years, mean: 54.3 ± 12.7 years) presented with acute massive upper gastrointestinal bleeding(n = 9) or refractory ascites(n = 2) due to tumor thrombus in the main portal vein. The diagnosis of PVTT was based on contrast-enhanced computed tomography and color Doppler sonography. The patients underwent TIPS with covered stents. Clinical characteristics and average survival time of 11 patients were analyzed. Portal vein pressure was assessed before and after TIPS. The follow-up period was 2-18 mo. RESULTS: TIPS with covered stents was successfully completed in all 11 patients. The mean portal vein pressure was reduced from 32.0 to 11.8 mmHg(t = 10.756, P = 0.000). Gastrointestinal bleeding was stopped in nine patients. Refractory ascites completely disappeared in one patient and was alleviated in another. Hepatic encephalopathy was observed in six patients and was resolved with drug therapy. During the follow-up, ultrasound indicated the patency of the shunt and there was no recurrence of symptoms. Death occurred 2-14 mo(mean: 5.67 mo) after TIPS in nine cases, which were all due to multiple organ failure. In the remaining two cases, the patients were still alive at the 16- and 18-mo follow-up, respectively. CONCLUSION: TIPS with covered stents for HCC patients with tumor thrombus in the main portal vein is technically feasible, and short-term efficacy is favorable. | Jian-Bo Zhao Chao Feng Qiao-Hua Zhu Xiao-Feng He Yan-Hao Li Yong Chen | 2014 | World Journal of Gastroenterology2014，20，6： | 12 |
| 6 | 三维打印辅助TIPS治疗肝硬化食管胃底静脉曲张出血显示文摘目的探讨三维打印辅助经颈静脉肝内门体分流术(TIPS)治疗肝硬化食管胃底静脉曲张出血的临床价值。方法30例肝硬化伴食管胃底静脉曲张出血患者随机分为病例组(n=15)和对照组(n=15)。病例组患者术前接受肝脏CT薄层扫描和门静脉系统CT静脉造影(CTV),根据扫描数据按1∶1打印肝脏血管模型,进行体外模拟穿刺,并调整RUPS-100型经颈静脉肝内穿刺系统穿刺针角度,制定最佳穿刺路径后行TIPS;对照组患者术前接受肝脏CT薄层扫描和门静脉系统CTV检查,凭经验行TIPS。比较两组术中穿刺针数、时长、穿刺成功率和穿刺相关并发症发生率。结果两组穿刺成功率均为100%。病例组穿刺针数、时长、穿刺相关并发症发生率均低于对照组,差异均有统计学意义(P<0.05)。结论三维打印辅助TIPS可减少穿刺次数,缩短穿刺时间,降低穿刺相关并发症发生率。 | 李伟之 郑君仪 于颖 刘梦莹 李培杰 马富权 薛挥 | 2019 | 介入放射学杂志2019，28，8： | 9 |
| 7 | 肝硬化伴门静脉血栓经颈静脉肝内门体分流术后分流道失功能的影响因素分析显示文摘目的探讨肝硬化合并门静脉血栓(PVT)经颈静脉肝内门体分流术(TIPS)术后分流道的疗效。方法回顾性分析2015年1月至2018年5月收治的肝硬化伴PVT行TIPS术治疗患者44例,收集患者的临床基线资料,记录手术前后门静脉压力梯度(PVPG),术后随访3、6、12、18、24个月时分流道支架通畅情况,对影响因素进行单因素及多因素分析。结果44例均成功建立肝内门腔分流道,术后PVPG均较术前下降(P值均<0.01)。PVT行TIPS术后分流道狭窄率为18.2%(n=8),术后3、6、12、18、24个月累积分流道支架通畅率分别为95.5%、90.7%、90.7%、86.8%、74.4%。单因素分析显示糖尿病史、血小板水平及凝血酶原时间国际标准化比值与术后分流道失功能有关,多因素分析显示糖尿病史(P=0.007,OR=28.606)是术后分流道失功能的独立风险因素。结论肝硬化PVT行TIPS手术安全可行,可有效降低门静脉压力,糖尿病患者术后分流道失功能风险较高,临床上应加强对高危风险患者的防治干预。 | 李旭 王宏亮 周坦洋 陈圣群 聂春晖 张岳林 余子牛 周官辉 朱统寅 孙军辉 | 2020 | 中华肝脏病杂志2020，28，9： | 9 |
| 8 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 9 | CDFI与实时组织弹性成像联合监测在肝硬化经颈内静脉肝内门体静脉分流术术后疗效的临床价值显示文摘目的探讨CDFI和实时组织弹性成像(RTE)联合监测在肝硬化经颈内静脉肝内门体静脉分流术(TIPSS)术后疗效的临床价值。方法对临床46例肝硬化门脉高压经TIPSS术前、术后进行CDFI和RTE检查。观察门静脉、脾静脉内径和血流变化情况;通过组织弥散定量分析软件分析肝硬化弥散指标变化情况。结果 TIPSS术后门静脉内径变小,门静脉、脾静脉流速增快,与术前比较差异有统计学意义(P<0.05),脾静脉内径改变不明显,与术前比较差异无统计学意义。TIPSS术后蓝色领域百分比增高,复杂度、峰度、偏度减低,与术前比较差异均有统计学意义(均P<0.05),TIPSS术前、后应变均值、标准偏差、对比度、均等性、杂乱度、一致性及相关性改变不明显。结论 CDFI技术在观察TIPSS术前后血管内径、血流速方面改变比较明显;RTE能观察到肝硬化TIPSS术后肝硬度的改变情况。二者联合诊断肝硬化TIPSS术后价值更高。 | 方彦鹏 段庆红 陈霞 胡晓丽 焦俊 | 2015 | 临床超声医学杂志2015，17，6： | 6 |
| 10 | 经颈静脉肝内门体分流术中穿刺门静脉不同支对术后肝性脑病发生率影响的系统评价显示文摘目的 探究经颈静脉肝内门体分流术(TIPS)中穿刺门静脉左支或右支对术后肝性脑病发生率的影响.方法 计算机检索PubMed、Cochrane Library、CNKI数字图书馆、万方数据库,纳入有关TIPS术中穿刺门静脉左支或右支对术后肝性脑病发生率影响的随机对照试验及队列研究,按Cochrane系统评价方法提取资料、评价文献质量并进行统计学分析,数据采用RevMan 5.0软件进行分析.结果 最终纳入1篇随机对照试验、4篇队列研究,共552例行TIPS术的肝硬化患者.以随机效应模型进行Meta分析,结果显示:TIPS术中穿刺门静脉左支作为分流道路径,较穿刺门静脉右支术后肝性脑病的发生率更低,RR=0.51,95%可信区间为0.39-0.66,P〈0.01.结论 TIPS术中穿刺门静脉左支作为分流道路径,较穿刺右支能明显降低术后肝性脑病的发生率. | 马富权 李伟之 李培杰 刘梦莹 郑君仪 薛挥 | 2017 | 中华放射学杂志2017，51，3： | 6 |
| 11 | 15例无消化道出血史的肝硬化患者经颈静脉肝内门体静脉分流术后现状调查显示文摘目的了解无消化道出血史的肝硬化患者经颈静脉肝内门体静脉分流术(TIPS)术后生存现状。方法对于2004年至2013年间自愿行TIPS的15例无消化道出血史的肝硬化患者进行随访追踪,了解其手术成功率及手术难度、肝性脑病发生率、消化道出血发生率、脾功能亢进改善等情况。结果手术成功率为100%,手术平均时间约60min。术后随访期间无支架成角畸形者;15例患者TIPS术后均未发生消化道出血;亦无患者死亡。有4例于术后8周内发生肝性脑病;4例患者贫血较术前改善。结论TIPS对肝硬化合并重度食管胃静脉曲张患者预防消化道出血安全有效,或可成为肝硬化无出血患者的一级预防治疗方案。 | 袁佳 薛挥 和水祥 李伟之 李培杰 | 2014 | 中华消化杂志2014，34，1： | 5 |
| 12 | 覆膜支架经颈静脉肝内门体分流术治疗门静脉主干癌栓显示文摘目的探讨Fluency覆膜支架经颈静脉肝内门腔分流术(TIPS)治疗门静脉主干癌栓并门静脉高压症的临床应用价值。方法对11例原发性肝癌伴门静脉主干癌栓导致门静脉高压症患者行TIPS术。其中9例为食管胃底静脉曲张合并急性出血,另2例为顽固性腹腔积液。TIPS术中采用Fluency覆膜支架建立肝内门腔分流道。测量支架置入前后的门静脉压力。术后随访1~18个月,分析疗效。结果 11例TIPS术均获成功,共置入21枚覆膜支架,直径8mm支架20枚,7mm支架1枚,支架长度4~8cm。平均门静脉压力由术前(32.00±4.12)mmHg降至(11.82±3.09)mmHg(t=10.76,P〈0.001)。6例在术后1周出现不同程度肝性脑病,经口服乳果糖等内科处理后症状消失。9例急性出血患者术后出血停止,另2例顽固性腹腔积液患者术后腹腔积液明显减少。随访期间,超声提示支架血流通畅,无复发。9例因多器官衰竭于术后2~14个月死亡[平均(5.67±4.00)个月];另2例分别随访16及18个月仍存活。结论对门静脉主干癌栓并门静脉高压症患者,采用覆膜支架行TIPS术是可行的,可有效控制近期门静脉高压相关症状。 | 冯超 赵剑波 陈勇 曾庆乐 罗泽龙 何晓峰 梅雀林 李彦豪 | 2014 | 中国介入影像与治疗学2014，11，12： | 4 |
| 13 | 经颈静脉肝内门体分流术术后抗血栓治疗的研究进展显示文摘目的 探讨经颈静脉肝内门体分流术(TIPS)术后抗血栓治疗的必要性及重要性。方法分别以“transjugularintrahepaticportosystemicshunt”、“门脉高压”为关键词在Pubmed及CNKI数据库检索1994年1月112014年6月关于TIPS治疗及术后评估的相关文献,分析TIPS术后血栓形成的原因、抗血栓治疗的意义及策略。结果TIPS术后分流道内血栓影响TIPS的疗效。抗血栓治疗可以提高支架通畅率,为保证TIPS手术疗效起关键作用。结论TIPS术后抗血栓治疗可以减少分流道血栓形成,对维持分流道通畅极为重要。 | 李洪翠 李肖 | 2016 | 中华解剖与临床杂志2016，21，1： | 3 |
| 14 | 早期应用经皮经肝穿刺肝内门体分流术治疗食管胃底静脉曲张破裂出血的近期疗效观察显示文摘目的观察经皮经肝穿刺肝内门体分流术(PTIPS)治疗肝硬化食管胃底静脉曲张出血近期疗效。方法对15例肝硬化食管胃底静脉曲张急性出血患者实施经皮经肝穿刺肝内门体分流术治疗,治疗后观察门静脉压力下降程度、肝性脑病发病率、再出血率、死亡率和食管胃底静脉曲张改变程度。结果患者行急诊PTIPS后门静脉压力由44.56±12.23 cm H2O降至18.21±5.35 cm H2O,门静脉压力下降明显(P〈0.05)。术后随访1~24月,随访期内,有1例患者术后6月再发出血;1例于术后第12月死亡;术后肝性脑病发生3例,肝性脑病发生率为20%。PTIPS治疗后食管胃底静脉曲张程度明显减轻(P〈0.05)。结论早期应用经皮经肝穿刺肝内门体分流术治疗肝硬化食管胃底静脉曲张出血手术成功率高、近期观察安全有效。 | 刘朝霞 刘浩雷 吴清 | 2015 | 中南医学科学杂志2015，43，4： | 3 |
| 15 | Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats显示文摘BACKGROUND: Prostacyclin has been shown to increase portal hypertension, but the mechanism is unclear. This study aimed to investigate whether the overproduction of prostacyclin(PGI2) in cirrhosis participates in the splanchnic vascular hyporesponsiveness to vasoconstrictors in cirrhotic rats.METHODS: Cirrhotic model was created by subcutaneous injection of 60% carbon tetrachloride(CCl4) corn oil solution combined with intermittent drinking of 5% alcohol, and agematched rats served as controls. The isolated third-generation mesenteric arterioles were used to examine the contractile response to norepinephrine. The changes in vascular diameter were observed under a microscope imaging device. The plasma concentration of 6-ketone-prostaglandin F1α(6-keto-PGF1α, a stable metabolite of PGI2) was tested via enzyme immunoassays and the expression of cyclooxygenase(COX) in mesenteric arteries was detected by Western blotting.RESULTS: In parallel with the increase of plasma 6-ketoPGF1α, the contractile response of arterioles from cirrhotic rats to norepinephrine was significantly impaired compared with that from controls. Inhibition of PGI2 or protein kinase A with indomethacin or Rp-adenosine 3', 5'-cyclic monophosphothioate(Rp-cAMPS) partially reversed the vascular hypo-contractile response to norepinephrine in arterioles from cirrhotic rats.Indomethacin significantly decreased the plasma 6-keto-PGF1α.Furthermore, indomethacin significantly attenuated the effect of Rp-cAMPS on arterioles from cirrhotic rats. COX-1 expression was up-regulated in mesenteric arteries from cirrhotic rats,whereas COX-2 was not detectable in the mesenteric arteries from both cirrhotic and control rats.CONCLUSION: Enhanced COX-1 expression in cirrhotic rats resulted in elevated PGI2 production which partially contributedto the splanchnic vascular hyporesponsiveness to a vasoconstrictor via the protein kinase A pathway. | De-Jun Liu Wei Chen Yan-Miao Huo Wei Liu Jun-Feng Zhang Rong Hua Yong-Wei Sun | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，4： | 2 |
| 16 | 过氧化氢在肝硬化门静脉高压症内脏高动力循环中的作用显示文摘目的探讨过氧化氢(H2O2)在门静脉高压症内脏高动力循环形成中的作用。方法雄性SD大鼠皮下注射四氯化碳(CCl4)制备肝硬化门静脉高压症(PHT)模型。PHT组大鼠制备完成后随机分为2个亚组:聚乙二醇-过氧化氢酶(PEG-catalase)处理组(PHT+PEG组)和生理盐水(NS)处理组(PHT+NS组),分别用PEG或NS腹腔内注射10 U/(g·d),共14 d。测定大鼠门静脉压力(PP)、肠系膜微动脉对去甲肾上腺素(NE)的反应性、肠系膜动脉内H2O2含量。结果 (1)PHT组PP明显高于非PHT组,PEG对PHT组PP并无明显改善(P>0.05);(2)PHT组肠系膜微动脉对NE的反应性明显低于非PHT组,血管收缩率50%时NE的浓度EC50明显升高(P<0.01),PEG能部分改善这种低反应性(P<0.01);(3)PHT组肠系膜动脉内H2O2明显升高,PEG能使其减少。结论肝硬化PHT中过度生成的H2O2可通过降低肠系膜动脉对NE的反应性参与高动力循环的形成。 | 刘杰凡 刘巍 孙勇伟 | 2014 | 肝胆胰外科杂志2014，26，6： | 1 |
| 17 | 经颈静脉肝内门腔分流术中肝外门静脉穿刺致腹腔出血处理的初步经验显示文摘经颈静脉肝内门腔分流术(transjugular intrahepatic portosystemic shunt,TIPS)可有效控制因门静脉高压导致的急慢性食管胃底静脉曲张破裂出血、顽固性腹水等症状[1-6].肝外门静脉穿刺致腹腔出血是TIPS术中最危重的并发症之一,文献报道发生率为1% ~ 2%[7].以往采用裸支架行TIPS术,如果出现肝外门静脉穿刺引起出血,术中出血量巨大,患者可很快出现失血性休克表现,处理多以球囊压迫的同时转外科开腹修补.覆膜支架的出现则可以较好地处理此种情况.自2005年起,笔者尝试以覆膜材料支架(Fluency支架,Bard公司,德国)作为替代产品行TIPS术,取得了满意疗效[8],同时发现采用Fluency覆膜支架对于TIPS术中出现的肝外门静脉穿刺致腹腔的出血也可以获得满意的效果,现将初步经验整理报道如下. | 冯超 陈勇 李彦豪 何晓峰 曾庆乐 梅雀林 王江云 庞桦进 赵剑波 | 2015 | 中华放射学杂志2015，49，3： | 0 |
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