|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 1990—2017年中国伤害负担:2017年全球疾病负担研究结果(摘译)显示文摘伤害是全球性的公共卫生挑战,涉及各年龄组和不同性别的人群。过去三十年来,中国经济快速发展,人口老龄化趋势加重,社会呈现出城镇化、机动化和老龄化等特征。随着人们生活环境和生活方式的改变,伤害已跃居人群致死原因第五位,仅排在恶性肿瘤、心脑血管疾病、呼吸系统疾病和心肌梗死之后。据估计,中国每年在伤害方面消耗的直接医疗费用约为650亿元人民币. | 林泽婷(译) 吕来文(译) 黄晓晴(译) 李丽萍(审校) Duan Leilei Ye Pengpeng Juanita A Haagsma Jin Ye Wang Yuan Er Yuliang Deng Xiao Gao Xin Ji Cuirong Wang Linhong Marlena S Bannick W Cli Mountjoy-Venning Caitlin N Hawley Zichen Liu Mari Smith Spencer L James Theo Vos Christopher J L Murray | 2020 | 伤害医学(电子版)2020，9，2： | 15 |
| 2 | Coupling effects of tungsten and molybdenum on microstructure and stress-rupture properties of a nickel-base cast superalloy显示文摘In order to comprehensively understand the forming mechanism of abnormal phases solidified in a nickel-base cast superalloy with additives of tungsten and molybdenum, the coupling effects of W and Mo on the microstructure and stress-rupture properties were investigated in this paper. The results indicated that the precipitation of primary α-(W, Mo) phase depended tremendously on the amount of W and Mo addition. When the total amount of W and Mo was greater than 5.79 at%, α-(W, Mo) phase became easily precipitated in the alloy.With increasing of Mo/W ratio, the dendrite-like α-(W, Mo) phases were apt to convert into small bars or blockylike phases at the vicinities of γ′/γ eutectic. The morphological changes of α-(W, Mo) phase can be interpreted as the non-equilibrium solidification of W and Mo in the alloy. Since the large sized α-(W, Mo) phase has detrimental effects on stress-rupture properties in as-cast conditions, secondary cracks may mainly initiate at and then propagate along the interfaces of brittle phases and soft matrix. During exposing at 1100 ℃ for 1000 h, the α-(W, Mo) phases transformed gradually into bigger and harder M_6C carbide, which results in decreasing of stress-rupture properties of the alloy. Finally, the alloy with an addition of 14W-1Mo(wt%) maintained the longest stress lives at high temperatures and therefore it revealed the best microstructure stability after 1100 ℃/1000 h thermal exposure. | Tongjin Zhou Wei Feng Huibin Zhao Yu Meng Huaxia Zhang Hongsheng Ding Zichen Wang | 2018 | Progress in Natural Science:Materials International2018，28，1： | 7 |
| 3 | First-generation EGFR tyrosine kinase inhibitor therapy in 106 patients with compound EGFR-mutated lung cancer: a single institution’s clinical practice experience显示文摘Background:The antitumour efficacy of tyrosine kinase inhibitors(TKIs)in lung cancer patients with compound epidermal growth factor receptor(EGFR)mutations has not been resolved.Our study summarizes a single institutional experience of first-generation TKI therapy for lung cancers with compound EGFR mutations.Methods:A total of 106 consecutive patients with tumours bearing compound EGFR mutations were identified between January 2012 and May 2016;all patients received first-generation TKI therapy.Deletions in exon 19 and the L858R point mutation in exon 21 were considered common mutations;T790M was considered separately because of its association with TKIs resistances.Any other mutation was defined as a rare mutation.Patients were divided as follows:double common mutations(group A);common plus T790M mutations(group B);common plus rare muta-tions(group C);double rare mutations(group D);and rare plus T790M mutations(group E).A separate group of 115 consecutive patients with a single common mutation was created for comparative analysis(group F).Results:The frequency of patients with compound EGFR was 2.9%(114/3925)and their response rate to first-genera-tion TKIs was 50.9%,which was not significantly different from group F(67.0%,P=0.088).The progression-free survival(PFS)of the 106 patients receiving TKI therapy was worse than that of group F(median,9.1 vs.13.0 months,respec-tively;P<0.001).The PFS of the compound mutation group was shorter than that of the single common mutation group(median,10.1 months in group A,P=0.240;9.1 months in group B,P<0.001;9.6 months in group C,P=0.010;6.5 months in group D,P=0.048;5.4 months in group E,P=0.017).Patients with a co-occurring mutation in exon 20(excluding T790M)exhibited significantly worse PFS than the patients with other compound mutations or with a single common mutation(median,6.5 vs.9.1 vs.13.0 months,respectively,P=0.002).Conclusions:There was significant heterogeneity among the compound EGFR mutations and their response to first-generation TKIs.Individualized treatment in clinical practice should be considered for each case. | Xiangyang Yu Xuewen Zhang Zichen Zhang Yongbin Lin Yingsheng Wen Yongqiang Chen Weidong Wang Lanjun Zhang | 2018 | Cancer Communications2018，38，1： | 5 |
| 4 | In situ synthesis and modification of calcium carbonate nanoparticles via a bobbling method显示文摘Modified calcium carbonate (CaCO3) nanoparticles with cubic- and spindle-like configuration were synthesized in situ by the typical bobbling (gas-liquid-solid) method. The modifiers, such as sodium stearate, octadecyl dihydrogen phosphate (ODP) and oleic acid (OA), were used to obtain hydrophobic nanoparticles. The different modification effects of the modifiers were investigated by measuring the active ratio, whiteness and the contact angle. Moreover, transmission electron microscopy (TEM), X-ray diffraction (XRD) and thermogravimetry analysis (TGA analysis) were employed to characterize the obtained products. A preliminary reaction mechanism was discussed. According to the results, the active ratio of CaCO3 modified by ODP was ca. 99.9% and the value of whiteness was 97.3% when the dosage of modifiers reached 2%. The contact angle was 122.25° for the CaCO3 modified in the presence of sodium stearate, ODP and OA. When modified CaCO3 was filled into PVC, the mechanical properties of products were improved greatly such as rupture intensity, pull intensity and fuse temperature. The compatibility and affinity between the modified CaCO3 nanoparticles and the organic matrixes were greatly improved. | ZHAO LiNa FENG JingDong WANG ZiChen | 2009 | Science China Chemistry2009，52，7： | 5 |
| 5 | Epstein-Barr virus-encoded RNAs as a survival predictor in nasopharyngeal carcinoma显示文摘 | Ke Kengjian Wang Haiyun Fu Sha Zhang Zichen Duan Liping Liu Dabo Ye Jin | 2014 | Chinese Medical Journal2014，，2： | 5 |
| 6 | NON-CONTACT MEASUREMENT SYSTEM OF FREEFORM SURFACE AND NURBS RECONSTRUCTION OF MEASUREMENT POINTS显示文摘Based on the development of the non-contact measurement system of free-form surface, NURBS reconstruc-tion of measurement points of freeform surface is effectively realized by modifying the objective function and recursiveprocedure and calculating the optimum number of control points. The reconstruction precision is evaluated through Ja-cobi's transformation method. The feasibility of the measurement system and effectiveness of the reconstruction algo-rithm above are proved by experiment. | Li Jian Wang Wen Chen Zichen Institute of Advanced Manufacturing Engineering, Zhejiang University, Hangzhou 310027, China | 2002 | Chinese Journal of Mechanical Engineering2002，15，4： | 4 |
| 7 | Inhibition of in-stent restenosis after graphene oxide double-layer drug coating with good biocompatibility显示文摘In this study,we designed a double layer-coated vascular stent of 316L stainless steel using an ultrasonic spray system to achieve both antiproliferation and antithrombosis.The coating included an inner layer of graphene oxide(GO)loaded with docetaxel(DTX)and an outer layer of carboxymethyl chitosan(CMC)loaded with heparin(Hep).The coated surface was uniform without aggregation and shedding phenomena before and after stent expanded.The coating treatment was able to inhibit the adhesion and activation of platelets and the proliferation and migration of smooth muscle cells,indicating the excellent biocompatibility and antiproliferation ability.The toxicity tests showed that the GO/DTX and CMC/Hep coating did not cause deformity and organ abnormalities in zebrafish under stereomicroscope.The stents with GO double-layer coating were safe and could effectively prevent thrombosis and in-stent restenosis after the implantation into rabbit carotid arteries for 4–12 weeks. | Shuang Ge Yadong Xi Ruolin Du Yuzhen Ren Zichen Xu Youhua Tan Yazhou Wang Tieying Yin Guixue Wang | 2019 | Regenerative Biomaterials2019，6，5： | 4 |
| 8 | Aberrant seed development in Litchi chinensis is associated with the impaired expression of cell wall invertase genes显示文摘Cell wall invertase(CWIN)are known to play important roles in seed development.However,most reports to date have focused on a single gene family member,and have mainly investigated CWIN functions during the filling stage of seed development.In this study,we found significant lower levels of CWIN protein and activity associated with seed abortion in the Litchi chinensis cultivar“Nuomici.”We identified five litchi CWIN genes and observed that the expression of LcCWIN5 was limited to the flower tissues and decreased sharply with fruit development.Silencing of LcCWIN5 expression before 28 DAA(cell division stage)resulted in perturbed liquid endosperm development,smaller seeds,and higher seed abortion rate,while silencing after 28 DAA(filling stage)had no effect on seed development.In contrast,LcCWIN2 was mostly expressed in the funicle and seed coat,and increased with fruit development.Decreased LcCWIN2 expression and CWIN activity during early seed filling coincided with smaller seeds in the cultivar“Feizixiao.”Silencing of LcCWIN2 caused a reduction in the seed size without inducing seed abortion.We propose that CWIN activity in seed maternal tissues during cell division stage is likely due to LcCWIN5 expression,which regulates early seed development.On the other hand,CWIN activity during the filling stage is due to the expression of LcCWIN2,which may promote carbon import by creating a sucrose gradient.Comparable LcCWIN5 expression,but much lower CWIN activity,detected in the funicle of“Nuomici”is consistent with post-translational regulation. | Jieqiong Zhang Zichen Wu Fuchu Hu Lian Liu Xuming Huang Jietang Zhao Huicong Wang | 2018 | Horticulture Research2018，5，1： | 4 |
| 9 | Regulating Mechanical Properties of Polymer-Supramolecular Double-Network Hydrogel by Supramolecular Self-assembling Structures显示文摘Main observation and conclusion Polymer-supramolecular double-network hydrogels(PS-DN hydrogels)often show much improved recovery rates than conventional double-network hydrogels because of the fast self-assembling properties,making them attractive candidates for tissue engineering and flexible electronics.However,as the supramolecular network is dynamic and susceptible to break under low strains,the overall mechanical properties of PS-DN hydrogels are still limited.Here,we report the mechanical properties for PS-DN hydrogels can be significantly improved by tuning the supramolecular network structures.A single amino acid change of the self-assembling peptide can tune the assembled structures from nanofiber to nanoribbon.Such a microscopic structural change can greatly increase the Young's modulus(107.4 kPa),fracture stress(0.48 MPa),and toughness(0.38 MJ·m^(–3))of the PS-DN hydrogels.Moreover,the structural change also leads to slightly faster recovery rates(<1 s).We propose that such dramatically different mechanical properties can be understood by the impact of individual peptide rupture events on the overall network connectivity in the two scenarios.Our study may provide new inspirations for combining high mechanical strength and fast recovery in double network hydrogels by tuning the supramolecular network structures. | Tiankuo Wang Yu Zhang Zichen Gu Wei Cheng Hai Lei Meng Qin Bin Xue Wei Wang Yi Cao | 2021 | Chinese Journal of Chemistry2021，39，10： | 4 |
| 10 | GENERATE TRIANGUUTED SURFACES FROM MASSIVE UNORGANIZED POINTS显示文摘triangulated 从巨大的未组织起来的点出现的为重建的一个成长区域的方法被介绍。节省记忆空间,戒指数据结构被采用造在点和 triangulated 表面之间的连接。数据结构允许所有附近的顶点的有效检索和给定的绿色冰的三角形。为了缩小搜索,邻近的点变化并且避免 trinangle 交叉,一个影响区域为 eachactive 边被定义。在 triangulated 表面的成长区域的过程, minimum-edge-angle-productalgorithm 被提出选择一个适当的点为一个活跃的边形成一个新三角形。结果显示介绍方法有高效率并且需要更少的存储器空格,有可靠拓扑的质量的优化 triangulated 表面能在三角测量以后被获得。 | WU Shixiong WANG Chengyong CHEN Zichen | 2006 | Chinese Journal of Mechanical Engineering2006，19，1： | 3 |
| 11 | NeuroBiometric:An Eye Blink Based Biometric Authentication System Using an Event-Based Neuromorphic Vision Sensor显示文摘The rise of the Internet and identity authentication systems has brought convenience to people's lives but has also introduced the potential risk of privacy leaks.Existing biometric authentication systems based on explicit and static features bear the risk of being attacked by mimicked data.This work proposes a highly efficient biometric authentication system based on transient eye blink signals that are precisely captured by a neuromorphic vision sensor with microsecond-level temporal resolution.The neuromorphic vision sensor only transmits the local pixel-level changes induced by the eye blinks when they occur,which leads to advantageous characteristics such as an ultra-low latency response.We first propose a set of effective biometric features describing the motion,speed,energy and frequency signal of eye blinks based on the microsecond temporal resolution of event densities.We then train the ensemble model and non-ensemble model with our Neuro Biometric dataset for biometrics authentication.The experiments show that our system is able to identify and verify the subjects with the ensemble model at an accuracy of 0.948 and with the non-ensemble model at an accuracy of 0.925.The low false positive rates(about 0.002)and the highly dynamic features are not only hard to reproduce but also avoid recording visible characteristics of a user's appearance.The proposed system sheds light on a new path towards safer authentication using neuromorphic vision sensors. | Guang Chen Fa Wang Xiaoding Yuan Zhijun Li Zichen Liang Alois Knoll | 2021 | IEEE/CAA Journal of Automatica Sinica2021，8，1： | 3 |
| 12 | CNC NON-CONTACT MEASURING SYSTEM FOR FREEFORM SURFACE显示文摘Developing CNC measuring method on the base of coordinate machine can make the best of the hardware resource of CNC system and realize the integration of CAD/CAM/CAT. Based on the evenly spaced parallel planes scanning, a new adaptive digitizing approach for freeform surface namely arc length extrapolation is put forward. By this way, the digitizing approach can be added to the CNC system, while the system's hardware and software are not changed. | JuHua Wang Wen Chen Zichen Li Jian Wang Hengkui Institute of Production Engineering, Zhejiang University, Hangzhou 310027, China | 2002 | Chinese Journal of Mechanical Engineering2002，15，2： | 3 |
| 13 | Particle swarm optimization-based algorithm of a symplectic method for robotic dynamics and control显示文摘Multibody system dynamics provides a strong tool for the estimation of dynamic performances and the optimization of multisystem robot design. It can be described with differential algebraic equations(DAEs). In this paper, a particle swarm optimization(PSO) method is introduced to solve and control a symplectic multibody system for the first time. It is first combined with the symplectic method to solve problems in uncontrolled and controlled robotic arm systems. It is shown that the results conserve the energy and keep the constraints of the chaotic motion, which demonstrates the efficiency, accuracy, and time-saving ability of the method. To make the system move along the pre-planned path, which is a functional extremum problem, a double-PSO-based instantaneous optimal control is introduced. Examples are performed to test the effectiveness of the double-PSO-based instantaneous optimal control. The results show that the method has high accuracy, a fast convergence speed, and a wide range of applications.All the above verify the immense potential applications of the PSO method in multibody system dynamics. | Zhaoyue XU Lin DU Haopeng WANG Zichen DENG | 2019 | Applied Mathematics and Mechanics(English Edition)2019，40，1： | 3 |
| 14 | High-Performance Photo-Modulated Thin-Film Transistor Based on Quantum dots/Reduced Graphene Oxide Fragment-Decorated ZnO Nanowires显示文摘In this paper, a photo-modulated transistor based on the thin-film transistor structure was fabricated on the flexible substrate by spin-coating and magnetron sputtering. A novel hybrid material that composed of Cd Se quantum dots and reduced graphene oxide(RGO) fragment-decorated ZnO nanowires was synthesized to overcome the narrow optical sensitive waveband and enhance the photo-responsivity. Due to the enrichment of the interface and heterostructure by RGO fragments being utilized, the photo-responsivity of the transistor was improved to 2000 AW^(-1) and the photo-sensitive wavelength was extended from ultraviolet to visible. In addition, a positive back-gate voltage was employed to reduce the Schottky barrier width of RGO fragments and ZnO nanowires. As a result, the amount of carriers was increased by 10 folds via the modulation of back-gate voltage. With these inherent properties, such as integrated circuit capability and wide optical sensitive waveband, the transistor will manifest great potential in the future applications in photodetectors. | Zhi Tao Yi-an Huang Xiang Liu Jing Chen Wei Lei Xiaofeng Wang Lingfeng Pan Jiangyong Pan Qianqian Huang Zichen Zhang | 2016 | Nano-Micro Letters2016，8，3： | 2 |
| 15 | Dynamic modeling and simulation of deploying process for space solar power satellite receiver显示文摘To reveal some dynamic properties of the deploying process for the solar power satellite via an arbitrarily large phased array(SPS-ALPHA) solar receiver, the symplectic Runge-Kutta method is used to simulate the simplified model with the consideration of the Rayleigh damping effect. The system containing the Rayleigh damping can be separated and transformed into the equivalent nondamping system formally to insure the application condition of the symplectic Runge-Kutta method First, the Lagrange equation with the Rayleigh damping governing the motion of the system is derived via the variational principle. Then, with some reasonable assumptions on the relations among the damping,mass, and stiffness matrices, the Rayleigh damping system is equivalently converted into the nondamping system formally, so that the symplectic Runge-Kutta method can be used to simulate the deploying process for the solar receiver. Finally, some numerical results of the symplectic Runge-Kutta method for the dynamic properties of the solar receiver are reported. The numerical results show that the proposed simplified model is valid for the deploying process for the SPS-ALPHA solar receiver, and the symplectic Runge-Kutta method can preserve the displacement constraints of the system well with excellent long-time numerical stability. | Tingting YIN Zichen DENG Weipeng HU Xindong WANG | 2018 | Applied Mathematics and Mechanics(English Edition)2018，39，2： | 2 |
| 16 | AED-Net:An Abnormal Event Detection Network显示文摘It has long been a challenging task to detect an anomaly in a crowded scene.In this paper,a selfsupervised framework called the abnormal event detection network(AED-Net),which is composed of a principal component analysis network(PCAnet)and kernel principal component analysis(kPCA),is proposed to address this problem.Using surveillance video sequences of different scenes as raw data,the PCAnet is trained to extract high-level semantics of the crowd’s situation.Next,kPCA,a one-class classifier,is trained to identify anomalies within the scene.In contrast to some prevailing deep learning methods,this framework is completely self-supervised because it utilizes only video sequences of a normal situation.Experiments in global and local abnormal event detection are carried out on Monitoring Human Activity dataset from University of Minnesota(UMN dataset)and Anomaly Detection dataset from University of California,San Diego(UCSD dataset),and competitive results that yield a better equal error rate(EER)and area under curve(AUC)than other state-of-the-art methods are observed.Furthermore,by adding a local response normalization(LRN)layer,we propose an improvement to the original AED-Net.The results demonstrate that this proposed version performs better by promoting the framework’s generalization capacity. | Tian Wang Zichen Miao Yuxin Chen Yi Zhou Guangcun Shan Hichem Snoussi | 2019 | Engineering2019，5，5： | 2 |
| 17 | RESEARCH ON ADAPTIVE DATA COMPRESSION METHOD FOR TRIANGULATED SURFACES显示文摘NC code or STL file can be generated directly from measuring data in a fast reverse-engineering mode.Compressing the massive data from laser scanner is the key of the new mode.An adaptive compression method based on triangulated-surfaces model is put forward.Normal-vector angles between triangles are computed to find prime vertices for removal.Ring data structure is adopted to save massive data effectively.It allows the efficient retrieval of all neighboring vertices and triangles of a given vertices.To avoid long and thin triangles,a new re-triangulation approach based on normalized minimum-vertex-distance is proposed,in which the vertex distance and interior angle of triangle are considered.Results indicate that the compression method has high efficiency and can get reliable precision.The method can be applied in fast reverse engineering to acquire an optimal subset of the original massive data. | Wang Wen Wu Shixiong Chen Zichen Department of Mechanical Engineering,Zhejiang University,Hangzhou 310027, China | 2004 | Chinese Journal of Mechanical Engineering2004，17，2： | 2 |
| 18 | Synthe-sis of ordered arrays of magnesium hydroxide nanoparti-cles via a simple method显示文摘 | An Dongmin Ding Xuefeng Wang Zichen | | 0，，356： | 1 |
| 19 | A novel mesoporous lignin/silica hybrid from rice husk produced by a sol–gel method显示文摘 | Yuning Qu Yumei Tian Bo Zou Jian Zhang Yunhui Zheng Lili Wang Ying Li Chunguang Rong Zichen Wang | 2010 | Bioresource Technology2010，，21： | 1 |
| 20 | A study on the consecutive preparation of silica powders and active carbon from rice husk ash显示文摘 | Dongmin An Yupeng Guo Bo Zou Yanchao Zhu Zichen Wang | 2011 | Biomass and Bioenergy2011，，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员