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| 1 | International Association of Diabetes and Pregnancy Study Group criteria is suitable for gestational diabetes mellitus diagnosis: further evidence from China显示文摘 | Wei Yumei Yang Huixia Zhu Weiwei Yang Hongyun Li Haixia Yan Jie Zhang Cuilin | 2014 | Chinese Medical Journal2014，，20： | 129 |
| 2 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 3 | Comparing the Diagnostic Criteria for Gestational Diabetes Mellitus of World Health Organization 2013 with 1999 in Chinese Population显示文摘INTRODUCTION Gestational diabetes mellitus (GDM) was earlier defined as 'hyperglycemia first recognized during pregnancy' and has more recently been described by American Diabetes Association (ADA) (2012) as diabetes diagnosed during pregnancy that is not clearly overt diabetes.[1] The hyperglycemia and adverse pregnancy outcomes study (HAPO) demonstrated that the risk of adverse maternal,fetal,and neonatal outcomes continuously increase as a function of maternal glycemia at 24-28 weeks,even within ranges previously considered normal for pregnancy.[2] After reviewing the results of the HAPO study,many international diabetes study groups,including the International Association of Diabetes and Pregnancy Study Groups and ADA have adopted the 75 g oral glucose tolerance test (OGTT) at 24-28 weeks as a screening and diagnostic test and defined new cut-off values for GDM diagnosis.The Ministry of Health of China published the criteria for GDM,that is the same as the ADA criteria on July 1,2011.World Health Organization (WHO) has recommended the 75 g OGTT with different cut-offvalues as a diagnostic test since 1999,changed its recommendation on 2013.In Hongkong and Yunnan province in China,most hospital adopted the WHO 1999 criteria,nevertheless,there is no evidence of multicenter and large sample to show that the GDM population within the same ethnic group diagnosed by the new WHO criteria matches those diagnosed by the old one and consistency between the two criteria has not been reported.Thus,we conducted this study to analyze the two criteria in Chinese pregnant women. | Weiwei Zhu Huixia Yang Yumei Wei Zilian Wang Xuelan Li Hairong Wu Nan Li Meihua Zhang Xinghui Liu Hua Zhang Yunhui Wang Jianmin Niu Yujie Gan Liruo Zhong Yunfeng Wang Anil Kapur | 2015 | Chinese Medical Journal2015，，1： | 42 |
| 4 | Microsatellite analysis of genetic diversity and population structure of Chinese mitten crab (Eriocheir sinensis)显示文摘中国露指手套螃蟹(Eriocheir sinensis ) 在中国比 Eriocheir 的任何另外的种类作为食物来源有更高商业的价值。为了评估细菌原生质资源并且在不同的水系统,二张股票和二张耕作人口描绘基因差异和螃蟹的人口结构,与在公共场合可得到的 25 多态的 microsallite loci 被估计 GenBank。基本统计证明一般水准观察了杂合现象(惊讶) 在人口之中从 0.5789 ~ 0.6824 。然而,使近交的显著存在和异质接合体缺乏被观察。到分析人口结构,配对系数从露指手套螃蟹人口的分向仅仅 10.3% 可变性解释了的明智的 FST,留下的可变性在潜水艇人口以内源自分。尽管四张人口有细微区别,不同突变而产生之遗传的频率导致了不同人口结构。二张股票和股票耕作人口一起被聚类到 Yangtze 螃蟹的种系发生的分支,与 95% 的一个近似会员。而,另一张耕作人口单身地被聚类到 Liaohe 螃蟹的种系发生的分支,与 97.1% 的一个会员。为单个混合的测试证明那只 Yangtze 螃蟹可能从另外的水系统与个人一起被污染了。在人口之间的基因关系也支持了尽管有一样的种类的起源,那只 Yangtze 螃蟹和 Liaohe 螃蟹有不同基因库的结论。 | Yumei Chang Liqun Liang Haitao Ma Jianguo He Xiaowen Sun | 2008 | Journal of Genetics and Genomics2008，35，3： | 29 |
| 5 | One-year clinical study of NeuroR egen scaffold implantation following scar resection in complete chronic spinal cord injury patients显示文摘The objective of this clinical study was to assess the safety and feasibility of the collagen scaffold, Neuro Regen scaffold, one year after scar tissue resection and implantation. Scar tissue is a physical and chemical barrier that prevents neural regeneration. However, identification of scar tissue is still a major challenge. In this study, the nerve electrophysiology method was used to distinguish scar tissue from normal neural tissue, and then different lengths of scars ranging from 0.5–4.5 cm were surgically resected in five complete chronic spinal cord injury(SCI) patients. The NeuroR egen scaffold along with autologous bone marrow mononuclear cells(BMMCs), which have been proven to promote neural regeneration and SCI recovery in animal models, were transplanted into the gap in the spinal cord following scar tissue resection. No obvious adverse effects related to scar resection or Neuro Regen scaffold transplantation were observed immediately after surgery or at the 12-month follow-up. In addition, patients showed partially autonomic nervous function improvement, and the recovery of somatosensory evoked potentials(SSEP) from the lower limbs was also detected. The results indicate that scar resection and Neuro Regen scaffold transplantation could be a promising clinical approach to treating SCI. | Zhifeng Xiao Fengwu Tang Jiaguang Tang Huilin Yang Yannan Zhao Bing Chen Sufang Han Nuo Wang Xing Li Shixiang Cheng Guang Han Changyu Zhao Xiaoxiong Yang Yumei Chen Qin Shi Shuxun Hou Sai Zhang Jianwu Dai | 2016 | Science China(Life Sciences)2016，59，7： | 18 |
| 6 | Breast milk macronutrient composition and the associated factors in urban Chinese mothers显示文摘 | Yang Titi Zhang Yumei Ning Yibing You Lili Ma Defu Zheng Yingdong Yang Xiaoguang Li Wenjun Wang Junkuan Wang Peiyu | 2014 | Chinese Medical Journal2014，，9： | 17 |
| 7 | On Improved DV-Hop Localization Algorithm for Accurate Node Localization in Wireless Sensor Networks显示文摘Node Localization is a fundamental issue for many critical applications in Wireless sensor networks(WSNs). Traditional DV-Hop localization algorithm and corresponding improved ones still cannot provide sufficient localization accuracy in such WSNs. To ensure accurate localization, this paper proposes an improved Distancevector-Hop(DV-Hop) localization algorithm. Under such an algorithm, we determine a corrected average hopdistance of beacon nodes by employing the differences between actual and estimated distance among beacon nodes in WSNs. We propose a probability information based selective strategy for the selection of beacon nodes.Based on these selected beacon nodes, we adopt a two dimensional hyperbolic function to predict the locations of unknown nodes. Simulation results are provided to illustrate the localization accuracy of our algorithm compared with traditional DV-Hop algorithm and its two improved algorithms in WSNs. | SHEN Shikai YANG Bin QIAN Kaiguo SHE Yumei WANG Wu | 2019 | Chinese Journal of Electronics2019，28，3： | 15 |
| 8 | Remediation of saline–sodic soil with flue gas desulfurization gypsum in a reclaimed tidal flat of southeast China显示文摘Salinization and sodicity are obstacles for vegetation reconstruction of coastal tidal flat soils. A study was conducted with flue gas desulfurization(FGD)-gypsum applied at rates of 0, 15, 30, 45 and 60 Mg/ha to remediate tidal flat soils of the Yangtze River estuary.Exchangeable sodium percentage(ESP), exchangeable sodium(ExNa), p H, soluble salt concentration, and composition of soluble salts were measured in 10 cm increments from the surface to 30 cm depth after 6 and 18 months. The results indicated that the effect of FGD-gypsum is greatest in the 0–10 cm mixing soil layer and 60 Mg/ha was the optimal rate that can reduce the ESP to below 6% and decrease soil p H to neutral(7.0). The improvement effect was reached after 6 months, and remained after 18 months. The composition of soluble salts was transformed from sodic salt ions mainly containing Na^+, HCO_3^-+ CO_3^(2-)and Cl-to neutral salt ions mainly containing Ca^(2+)and SO_4^(2-). Non-halophyte plants were survived at 90%. The study demonstrates that the use of FGD-gypsum for remediating tidal flat soils is promising. | Yumei Mao Xiaping Li Warren A.Dick Liming Chen | 2016 | Journal of Environmental Sciences2016，28，7： | 14 |
| 9 | Characteristics of change in water quality along reclaimed water intake area of the Chaobai River in Beijing, China显示文摘To reveal the basic characteristics and controlling factors of water quality change in the project Wenyu to Chaobai reclaimed water diversion, the water quality in the study area was monitored for one year at seven monitoring sites. Inverse geochemical models of the statistical groups were developed using PHREEQC to elucidate the hydrochemistry characteristics of reclaimed water and the factors. The monitoring results indicated that nitrogen and phosphorus contents were significantly reduced along the river mainly caused by seasonal and location variation. The pH ranged from 7.44 to 9.81. Photosynthesis of algae and denitrification in anaerobic microenvironment ultimately led to a sudden p H increase after the Jian River and the Chaobai River confluence. Mg^(2+)and SO_4^(2-) levels dropped obviously in the summer and increased in winter seasons after intersection. Na+and Cl-are relatively stable, and marked drop in the concentration only after the two rivers meet. And there is a decrease of Ca^(2+) and HCO^(3-) and increase in CO_3^(2-) during monitoring period. As a whole, the primary ions and nutrient components, including nitrogen and phosphorus, had high levels in winter. Algae's photosynthesis and respiration were observed to have an impact on the river water quality; there was precipitation–dissolution of minerals and denitrification from upstream to downstream. Inverse geochemical PHREEQC modeling confirmed that there was precipitation of aragonite or calcite, and gypsum or anhydrite in summer, and dissolution in winter; as well as precipitation of dolomite in winter, and cationic exchange and denitrification along the river. | Lei Yang Jiangtao He Yumei Liu Jian Wang Lie Jiang Guangcai Wang | 2016 | Journal of Environmental Sciences2016，28，12： | 14 |
| 10 | Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide显示文摘 | Sun Ling Sun Shuo Li Yufen Pan Wei Xie Yumei Wang Shushui Zhang Zhiwei | 2014 | Chinese Medical Journal2014，，5： | 13 |
| 11 | Microcalorimetric investigation of effect of berberine alkaloids from Coptis chinensis Franch on intestinal diagnostic flora growth显示文摘The inhibitory effect of three berberine alkaloids (BAs) from Coptis chinensis Franch, a traditional Chinese medicinal (TCM) herb, on Bifidobacterium adolescentis growth was investigated by micro- calorimetry. The power-time curves of B. adolescentis with and without BAs were acquired, meanwhile the extent and duration of inhibitory effect on the metabolism were evaluated by the growth rate con- stant (k), half inhibitory ratio (IC50), maximum heat-output power (Pmax), peak time of maximum heat-output power (tp) and total heat production (Qt). k, Pmax and Qt decreased, and tp was prolonged with the increase of BAs concentration. The IC50 of BAs is 806 μg/mL for berberine, 341 μg/mL for cop- tisine and 236 μg/mL for palmatine. The sequence of antimicrobial activity of BAs is berberine < cop- tisine < palmatine. Combined with previous studies, it could be shown that the sequences of antim- icrobial activity of BAs on both Bacillus shigae and Escherichia coli are berberine > coptisine > pal- matine. The structure-function relationship of BAs indicates that the functional group methylenedioxy or methoxyl at C2 and C3 might be the major group inducing the activities of BAs on E. coli and B. adolescentis. Meanwhile, the substituent groups at C2, C3, C9 and C10 almost have equal effect on B. shigae. | YAN Dan WEI Li XIAO XiaoHe ZHOU DanLei HAN YuMei | 2009 | Chinese Science Bulletin2009，54，3： | 12 |
| 12 | Peaked abundance of Calanus sinicus earlier shifted in the Changjiang River (Yangtze River) Estuary:a comparable study between 1959,2002 and 2005显示文摘The sea surface temperature (SST) of the East China Sea (ECS) increased in the past decades,which may have a great impact on the ecosystem of the ECS,including the changes in plankton-population structure.In this paper,the changes in peaked abundance of Calanus sinicus in the Changjiang River (Yangtze River) Estuary were compared between 1959 and 2002,based on the data collected from the seasonally oceanographic cruises and those performed in spring of 2005.It was much higher in spring compared with that in other seasons both in 1959 and 2002.Furthermore,in spring 2005,the time for occurrence and decrease of the peaked C.sinicus abundance advanced about one month, accompanying the increase in the sea surface water temperature (SST).It peaked in June and decreased in July in 1959,however,in 2005,it peaked in May and attenuated sharply in early June.The earlier decrease of peaked C.sinicus abundance may further deteriorate the ecosystem in the Changjiang River Estuary and north nearshore of the ECS. | XU Zhaoli MA Zengling WU Yumei | 2011 | Acta Oceanologica Sinica2011，30，3： | 11 |
| 13 | Heterotic Group Classification of 63 Inbred Lines and Hybrid Purity Identification by Using SSR Markers in Winter Cabbage(Brassica Oleracea L. var. capitata)显示文摘Winter cabbage is an important crop cultivated through winter in the region near the Yangtze River, enabling the supply of fresh cabbage there at that time of year. However, a problem has emerged regarding the newly developed parents of winter cabbage, which is completely different from spring and autumn cabbage, namely, how to combine these parents to breed an elite hybrid. To classify the heterotic groups and improve the efficiency of parent selection in winter cabbage breeding, 20 polymorphic SSR markers were selected to screen 63 winter cabbage inbred lines. Seventeen pairs among the 20 SSR markers amplified polymorphic bands. These primers amplified two to six bands,with an average of 2.8 bands per primer, and a total of 47 polymorphic bands were generated in the 63 inbred lines. These lines included flatheaded morphotype and round-headed morphotype, thus they were separately classified into heterotic groups based on the SSR markers. The flat-headed morphotype contained 21 inbred lines and was classified into three heterotic groups, named Hanchun 4, Jiali, and Dongsheng, in accordance with the representative germplasm contained in each group. The round-headed morphotype contained 42 inbred lines and was classified into five heterotic groups, named Parte, Bejo1039, YK-143, SCA002, and Golden B90. Meanwhile, parent analysis of 20 developed elite combinations showed that their parents were all distributed in different heterotic groups, indicating that the group classification was reasonable,which can provide a basis for further parent selection in winter cabbage breeding. Furthermore, polymorphic SSR primers were successfully used to identify the hybrid purity of three elite varieties. | LI Xing YU Hailong LI Zhiyuan LIU Xiaoping FANG Zhiyuan LIU Yumei YANG Limei ZHUANG Mu LV Honghao ZHANG Yangyong | 2018 | Horticultural Plant Journal2018，4，4： | 11 |
| 14 | Identification of a senescence-related protease in coriander leaves显示文摘Senescence-related protease may play an important role in leaf senescence. By improved SDS-Gela-tin-PAGE assay, a 63 ku senescence-related protease (63 SRP) in coriander leaves was identified. Activity of 63 SRP was increased in parallel to the advance of coriander leaf senescence, and inhibited by treating the leaf with gibberellic acid, and enhanced by ethylene treatment. The 63 SRP was suggested to be a serine protease based on the fact that its activity was inhibited by the protease inhibitor PMSF. The optimal temperature for the activity of the 70 ku protease was 50°C. The maximal activity was observed at pH 6-9, some activity could be observed on the gel slices incubated at pH 5 or 11. The 63 SRP was partly purified by the way of ammonium sulfate precipitation and then gel slicing after gel elec-trophoresis. | Weibo Jiang Xiangjuan Zhou Yumei Zhao Pengcheng Liu | 2002 | Chinese Science Bulletin2002，47，13： | 10 |
| 15 | Experimental research on hydrophilic characteristics of natural soft rock at high stress state显示文摘In order to study features of rock–water interaction, a self-developed experimental system called Intelligent Testing System for Water Absorption in Deep Soft Rocks(ITSWADSR) was utilized to analyze the hydrophilic behaviors of natural soft rock at high stress state. Combining X-ray diffraction and mercury injection test, main influencing factors on hydrophilic characteristics were studied. According to the results, it could be concluded as the following:(1) the effective porosity, and the content of illite, illite/smectite formation(S = 5%) and kaolinite have positive correlation with the water absorption capacity of rock; meanwhile, the initial moisture content, fractal dimension of effective pores, illite/smectite formation(S = 30%) and chlorite present negative correlation;(2) among the positive factors, the ascending order is kaolinite, illite/smectite formation(S = 5%) and illite;(3) the descending order among the negative factors are chlorite, illite/smectite formation(S = 30%) and fractal dimension of the effective pores;(4) influence of effective porosity on the pressurized water absorbing capacity of rock is minimal, while it is maximal in the process of no pressurized water absorption. | Guo Hongyun Lei Xiangyang Zhang Yumei Yang Guoxing Niu Zhang | 2015 | International Journal of Mining Science and Technology2015，25，3： | 10 |
| 16 | Effect of Reverse-threaded Pin on Mechanical Properties of Friction Stir Lap Welded Alclad 2024 Aluminum Alloy显示文摘In friction stir welding(FSW), tool geometry plays an important role in joint quality. In order to improve mechanical properties of friction stir lap welding(FSLW) joint, a tool with a reverse-threaded pin was designed in the present study. Using 2024-T4 aluminum alloy as the research object, tools with the fullthreaded pin and reverse-threaded pin were used in FSLW. Results showed that, when using the same parameter combination, FSLW joint using the reverse-threaded pin owned bigger effective sheet thickness(EST), bigger lap width and better lap shear failure strength. Compared with the full-threaded pin,fracture mode of the FSLW joint changed from shear fracture mode to tensile fracture mode when the reverse-threaded pin was used. Fracture morphologies presented ductile fracture. | Yumei Yue Zhengwei Li Shude Ji Yongxian Huang Zhenlu Zhou | 2016 | Journal of Materials Science & Technology2016，32，7： | 9 |
| 17 | Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model显示文摘Osteoarthritis(OA) is a degenerative joint disease and a major cause of pain and disability in older adults. We have previously identified epidermal growth factor receptor(EGFR) signaling as an important regulator of cartilage matrix degradation during epiphyseal cartilage development. To study its function in OA progression, we performed surgical destabilization of the medial meniscus(DMM) to induce OA in two mouse models with reduced EGFR activity, one with genetic modification(EgfrWa5/1mice) and the other one with pharmacological inhibition(gefitinib treatment). Histological analyses and scoring at 3 months post-surgery revealed increased cartilage destruction and accelerated OA progression in both mouse models. TUNEL staining demonstrated that EGFR signaling protects chondrocytes from OA-induced apoptosis, which was further confirmed in primary chondrocyte culture. Immunohistochemistry showed increased aggrecan degradation in these mouse models, which coincides with elevated amounts of ADAMTS5 and matrix metalloproteinase 13(MMP13), the principle proteinases responsible for aggrecan degradation, in the articular cartilage after DMM surgery. Furthermore, hypoxia-inducible factor 2a(HIF2a), a critical catabolic transcription factor stimulating MMP13 expression during OA, was also upregulated in mice with reduced EGFR signaling. Taken together, our findings demonstrate a primarily protective role of EGFR during OA progression by regulating chondrocyte survival and cartilage degradation. | Xianrong Zhang Ji Zhu Fei Liu Yumei Li Abhishek Chandra L Scott Levin Frank Beier Motomi Enomoto-Iwamoto Ling Qin | 2014 | Bone Research2014，2，3： | 9 |
| 18 | Optimized clinical practice for superaged patients with hip fracture:significance of damage control and enhanced recovery program显示文摘With the advent of global aging,the incidence,mortality,and medical costs of hip fracture among aged patients are increasing annually.The number of controlled clinical studies and health economics analyses that conform to evidence-based medicine principles is growing day by day.However,unfortunately,no specific recommendations regarding the procedures for the treatment of hip fracture are available.Meanwhile,the existence of both traditional treatment systems and new treatment theories means that most doctors confront difficult choices in their daily practice.These factors make the therapeutic approach for aged patients,especially among superaged patients with hip fracture,extremely challenging.This study focuses on superaged patients(>80 years as defined by the World Health Organization)with hip fracture and includes their preoperative pathological condition;therapeutic decision-making in terms of the benefit and risk ratio,damage control theory,and enhanced recovery after surgery were also investigated.These patients were discussed specifically by combining the current treatment strategies from several experts and the results of a meta-analysis published recently.The study presents some new ideas and approaches currently recognized in the field,such as preoperative assessment,surgical planning,safety consideration,complication intervention,and enhanced recovery implementation,and further presents some clear interpretations regarding misunderstandings in clinical practice.Finally,optimized treatment according to damage control principles and enhanced recovery after surgery during the perioperative period among superaged hip fracture patients is defined. | Zaiyang Liu Jun Zhang Kaiqi He Yumei Zhang Yuan Zhang | 2019 | Burns & Trauma2019，7，1： | 9 |
| 19 | Normal blood D-dimer concentrations: do they exclude pulmonary embolism?显示文摘 | Guo Zhiguo Ma Qingbian Zheng Yaan Zhang Yumei Ge Hongxia | 2014 | Chinese Medical Journal2014，，1： | 9 |
| 20 | LjCYC Genes Constitute Floral Dorsoventral Asymmetry in Lotus japonicus显示文摘Previous study shows that LjCYC2,a CYC-like TCP (TB1,CYC and PCFs) gene in the model legume,Lotus japonicus,is involved in dorsal petal development,which together with the other two homologous genes,LjCYC1 and LjCYC3,belongs to an LjCYC gene cluster.In this report,we modified the transformation system in L.japonicus,and constructed different RNAi transgenes to target different LjCYC genes.The expression of three endogenous LjCYC genes was specifically suppressed by different specific RNAi transgenes,and a chimerical RNAi transgene that contains the specific sequences from LjCYC1 and LjCYC2 was found to downregulate the expression of both endogenous genes simultaneously.Effects of silencing three LjCYC genes were mainly restricted on either dorsal or lateral petals,demonstrating their dorsalizing and lateralizing activities during the development of zygomorphic flower.Furthermore,abolishing the expression of three LjCYC genes could give rise to complete loss of dorsoventral (DV) differentiation in the flower whose petals all resembled the ventral one in the wild type and displayed intact organ internal (IN) asymmetry.Our data demonstrate that during zygomorphic flower development,the DV asymmetry is constituted by the LjCYC genes,while the floral organ IN asymmetry is independently determined by other genetic factors. | Jiechen Wang Yumei Wang Da Luo | 2010 | Journal of Integrative Plant Biology2010，52，11： | 8 |
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