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| 1 | Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration显示文摘房间通过 secreting 和释放蛋白质和泡与对方一起交流。许多房间能移居。在这研究,我们报导 migracytosis,为释放细胞的内容的房间迁居依赖者机制,和 migrasomes 的发现,调停的小囊的结构 migracytosis。当移居的房间移动,他们离开长管状的海滨,叫的收回纤维,在他们后面。大泡,包含众多的更小的泡,在收回纤维的尖端和交叉上成长。这些纤维,与主要房间身体连接泡,最后,裂缝,和泡被释放直到细胞外的空间或直接由包围房间收起。因为这些泡的形成是迁居依赖者,我们把他们称为 “ migrasomes”。我们也发现 cytosolic 内容能被搬运进 migrasomes 并且通过 migrasomes 免除了房间。我们把这迁居依赖者版本机制称为 “ migracytosis”。 | Liang Ma Ying Li Junya Peng Danni Wu Xiaoxin Zhao Yitong Cui Lilian Chen Xiaojun Yan Yanan Du Li Yu | 2015 | Cell Research2015,25,1: | 21 |
| 2 | A DC Grid Benchmark Model for Studies of Interconnection of Power Systems显示文摘Reducing carbon emissions in the power sector is critical for transitioning to a sustainable and low-carbon future.Estimating carbon efficiency of demand side response(DSR)in the power system is an important step towards realizing potential environmental benefits.Marginal emission factor(MEF)is an effective tool for estimating incremental changes in carbon emissions as a result of a change in demand.However,estimation methods currently used for evaluating MEF can be improved upon,specifically,by factoring in the ramp-rate constraint of generators in the fuel cost based merit order dispatch.In this paper is described a new method for MEF assessment under ramp-rate constraints;the method is then compared with two conventional estimations in a British power system.Three fuel price scenarios are used to conduct a sensitivity analysis of MEFs to fuel prices.Conclusions are drawn that can pave the way for future improvements in estimating MEF in power systems. | Ting An Xiaoxin Zhou Congda Han Yanan Wu Zhiyuan He Hui Pang Guangfu Tang | 2015 | CSEE Journal of Power and Energy Systems2015,1,4: | 17 |
| 3 | Study on gastric cancer blood plasma based on surface-enhanced Raman spectroscopy combined with multivariate analysis显示文摘A surface-enhanced Raman spectroscopy (SERS) method combined with multivariate analysis was developed for non-invasive gastric cancer detection. SERS measurements were performed on two groups of blood plasma samples: one group from 32 gastric patients and the other group from 33 healthy volunteers. Tentative assignments of the Raman bands in the measured SERS spectra suggest interesting cancer-specific biomolecular changes, including an increase in the relative amounts of nucleic acid, collagen, phospholipids and phenylalanine and a decrease in the percentage of amino acids and saccharide in the blood plasma of gastric cancer patients as compared with those of healthy subjects. Principal components analysis (PCA) and linear discriminant analysis (LDA) were employed to develop effective diagnostic algorithms for classification of SERS spectra between normal and cancer plasma with high sensitivity (79.5%) and specificity (91%). A receiver operating characteristic (ROC) curve was employed to assess the accuracy of diagnostic algorithms based on PCA-LDA. The results from this exploratory study demonstrate that SERS plasma analysis combined with PCA-LDA has tremendous potential for the non-invasive detection of gastric cancers. | FENG ShangYuan PAN JianJi WU YanAn LIN Duo CHEN YanPing XI GangQin LIN JuQiang CHEN Rong | 2011 | Science China(Life Sciences)2011,54,9: | 15 |
| 4 | An Operational Test Method for VSC-HVDC Valves Based on Modular Multi-level Converters显示文摘为给基于模块化多电平换流器(modular multi-levelconverter,MMC)的电压源换流器高压直流输电(voltagesourced converter HVDC,VSC-HVDC)换流阀提供有效的检验手段,以验证其设计的正确性及其运行可靠性,对换流阀的运行特性和关键应力进行分析,提出基于原理等效的MMC阀运行试验方法,设计试验电路并阐明其运行机理。搭建的PSCAD电磁暂态仿真模型和实际的试验验证证明了试验方法的正确性和有效性。 | WU Yanan LU Tianguang TANG Guangfu ZHA Kunpeng GAO Chong | 2012 | 中国电机工程学报2012,32,30: | 12 |
| 5 | Effect of cooling rates on the dendritic morphology transition of Mg–6Gd alloy by in situ X-ray radiography显示文摘The effect of cooling rate on the transition of dendrite morphology of a Mg-6 Gd(wt%) alloy was semiquantitatively analyzed under a constant temperature gradient by using synchrotron X-ray radiographic technique. Results show that equiaxed dendrites, including exotic 'butterfly-shaped' dendrite morphology, dominate at high cooling rate(>1 K/s). When the cooling rate decreases in the range of 0.5–1 K/s, the equiaxed-to-columnar transition takes place, and solute segregates at the center of two long dendrite arms(LDA) of the 'butterfly-shaped' dendrite. When the cooling rate is lower than 0.3 K/s, directional solidification occurs and the columnar dendritic growth direction gradually rotates from the crystalline axis to the thermal gradient direction with an increase in cooling rate. Meanwhile, interface moves faster but the dendrite arm spacing decreases. Floating, collision and rotation of dendrites under convection were also studied in this work. | Yongbiao Wang Liming Peng Yanzhou Ji Xiaoxing Cheng Cunlong Wang Yujuan Wu Yanan Fu Long-Qing Chen | 2018 | Journal of Materials Science & Technology2018,34,7: | 8 |
| 6 | Deep ultraviolet light-emitting diodes based on a well-ordered AlGaN nanorod array显示文摘The nanorod structure is an alternative scheme to develop high-efficiency deep ultraviolet light-emitting diodes(DUV LEDs). In this paper, we first report the electrically injected 274-nm AlGaN nanorod array DUV LEDs fabricated by the nanosphere lithography and dry-etching technique. Nanorod DUV LED devices with good electrical properties are successfully realized. Compared to planar DUV LEDs, nanorod DUV LEDs present>2.5 times improvement in light output power and external quantum efficiency. The internal quantum efficiency of nanorod LEDs increases by 1.2 times due to the transformation of carriers from the exciton to the free electron–hole, possibly driven by the interface state effect of the nanorod sidewall surface. In addition, the nanorod array significantly facilitates photons escaping from the interior of LEDs along the vertical direction, contributing to improved light extraction efficiency. A three-dimensional finite-different time-domain simulation is performed to analyze further in detail the TE-and TM-polarized photon extraction mechanisms of the nanostructure. Our results demonstrate the nanorod structure is a good candidate for high-efficiency DUV emitters. | LIANG ZHANG YANAN GUO JIANCHANG YAN QINGQING WU YI LU ZHUOHUI WU WEN GU XUECHENG WEI JUNXI WANG JINMIN LI | 2019 | Photonics Research2019,7,9: | 8 |
| 7 | Heterogeneous lamellar-edged Fe-Ni(OH)_(2)/Ni_(3)S_(2)nanoarray for efficient and stable seawater oxidation显示文摘Development of efficient non-precious catalysts for seawater electrolysis is of great significance but challenging due to the sluggish kinetics of oxygen evolution reaction(OER)and the impairment of chlorine electrochemistry at anode.Herein,we report a heterostructure of Ni_(3)S_(2)nanoarray with secondary Fe-Ni(OH)_(2)lamellar edges that exposes abundant active sites towards seawater oxidation.The resultant Fe-Ni(OH)_(2)/Ni_(3)S_(2)nanoarray works directly as a free-standing anodic electrode in alkaline artificial seawater.It only requires an overpotential of 269 mV to afford a current density of 10 mA·cm^(-2)and the Tafel slope is as low as 46 m V·dec^(-1).The 27-hour chronopotentiometry operated at high current density of 100 mA·cm^(-2)shows negligible deterioration,suggesting good stability of the Fe-Ni(OH)_(2)/Ni_(3)S_(2)@NF electrode.Faraday efficiency for oxygen evolution is up to〜95%,revealing decent selectivity of the catalyst in saline water.Such desirable catalytic performance could be benefitted from the introduction of Fe activator and the heterostructure that offers massive active and selective sites.The density functional theory(DFT)calculations indicate that the OER has lower theoretical overpotential than Cl_(2) evolution reaction in Fe sites,which is contrary to that of Ni sites.The experimental and theoretical study provides a strong support for the rational design of high-performance Fe-based electrodes for industrial seawater electrolysis. | Baihua Cui Zheng Hu Chang Liu Siliang Liu Fangshuai Chen Shi Hu Jinfeng Zhang Wei Zhou Yida Deng Zhenbo Qin Zhong Wu Yanan Chen Lifeng Cui Wenbin Hu | 2021 | Nano Research2021,14,4: | 7 |
| 8 | Novel hydrogen storage properties of palladium nanocrystals activated by a pentagonal cyclic twinned structure显示文摘研究人员们看起来忽视了雏晶的一种特殊形式,五角的周期的 twinning,明显的二维的格子扩大在存在导致新奇 physicalchemical 性质在几何、电子的结构与变化联系了。在 Pd nanocrystals 把氢的存储和版本用作一根探针,我们发现了五角的周期的孪生的 Pd nanocrystals 有的那 icosahedral 不同的氢存储性质由于二维的格子扩大,与那些相当不同八面的单个水晶的对应物。另外,在五角的周期的孪生的 Pd nanocrystals 的二维的格子扩大在电子结构引起一个变化,它导致在 PdH x 五角的周期的孪生的 nanocrystals。 | Huang Huang Shixiong Bao Qiaoli Chen Yanan Yang Zhiyuan Jiang Qin Kuang Xiaoyin Wu Zhaoxiong Xie Lansun Zheng | 2015 | Nano Research2015,8,8: | 7 |
| 9 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021,64,10: | 7 |
| 10 | Characterization of the soybean Gm ALMT family genes and the function of Gm ALMT5 in response to phosphate starvation显示文摘A potential mechanism to enhance utilization of sparingly soluble forms of phosphorus(P) is the root secretion of malate, which is mainly mediated by the ALMT gene family in plants. In this study, a total of 34 Gm ALMT genes were identified in the soybean genome. Expression patterns diverged considerably among Gm ALMTs in response to phosphate(Pi) starvation in leaves, roots and flowers, with expression altered by P availability in 26 of the 34 Gm ALMTs. One root-specific Gm ALMT whose expression was significantly enhanced by Pi-starvation,Gm ALMT_5, was studied in more detail to determine its possible role in soybean P nutrition. Analysis of Gm ALMT_5 tissue expression patterns, subcellular localization, and malate exudation from transgenic soybean hairy rootsoverexpressing Gm ALMT_5, demonstrated that Gm ALMT_5 is a plasma membrane protein that mediates malate efflux from roots. Furthermore, both growth and P content of transgenic Arabidopsis overexpressing Gm ALMT_5 were significantly increased when sparingly soluble Ca-P was used as the external P source. Taken together, these results indicate that members of the soybean Gm ALMT gene family exhibit diverse responses to Pi starvation. One member of this family, Gm ALMT_5, might contribute to soybean P efficiency by enhancing utilization of sparingly soluble P sources under P limited conditions. | Wenting Peng Weiwei Wu Junchu Peng Jiaojiao Li Yan Lin Yanan Wang Jiang Tian Lili Sun Cuiyue Liang Hong Liao | 2018 | Journal of Integrative Plant Biology2018,60,3: | 7 |
| 11 | Thermal Shock-Activated Spontaneous Growing of Nanosheets for Overall Water Splitting显示文摘Nanomaterials based on nickel foam(NF) have been widely applied in energy conversion and storage field.Traditional synthesis methods such as hydrothermal method which is dangerous and high cost limited the scalable developments.Herein,we report a fast,simple,and low-cost synthesis method of nanomaterials based on NF by Joule-heating and water soaking treatment.Thin carbon-coated CoS on NF(NF-C/CoS) was synthesized by Joule-heating for a few seconds with rapid cooling.And then,NF-C/CoS/NiOOH with core-shell heterostructure was fabricated by soaking treatment of NF-C/CoS in water on which NiOOH nanosheets grew spontaneously.The formation mechanism is proposed that the coordination complex precursor converts into C/CoS on NF driven by Joule-heating,and the nickel on the surface of NF is activated to form metastable nickel simultaneously.The metastable nickel reacting with water leads to the formation of NiOOH,and the induction of CoS makes NiOOH grow continuously.This synthesis technology provides a new route to manufacture NF-based nanostructures,and the as-fabricated NF-C/CoS/NiOOH exhibits great potential as electrocatalyst for oxygen evolution reaction and hydrogen evolution reaction. | Han Wu Qi Lu Jinfeng Zhang Jiajun Wang Xiaopeng Han Naiqin Zhao Wenbin Hu Jiajun Li Yanan Chen Yida Deng | 2020 | Nano-Micro Letters2020,12,11: | 6 |
| 12 | MnO_(2) cathode materials with the improved stability via nitrogen doping for aqueous zinc-ion batteries显示文摘The research and exploration of manganese-based aqueous zinc-ion batteries have been controversial of cycle stability and mechanism investigation,thus improving the stability and exploring storage mechanism are still the most main issue.Defect engineering has become an effective method to improve cycle stability.Herein,a nitrogen-doped ε-MnO_(2)(MnO_(2)@N)has been prepared using electrochemical deposition and heat treatment under nitrogen atmosphere.As the cathode for zinc-ion batteries,the capacity retention rate of MnO_(2)@N cathode is close to 100%after 500 cycles at 0.5 A g^(-1),while the capacity retention rate for the initial MnO_(2) cathode is 62%.At 5 A g^(-1),the capacity retention rate of MnO_(2)@N cathode is 83%after 1000 cycles,which is much higher than the 27%capacity retention rate for the original MnO_(2) cathode.And it can be found that the oxygen vacancies increase after nitrogen doping,which can improve the conductivity of the MnO_(2)@N cathode.Also,there is Mn-N bond in MnO_(2)@N,which can enhance the electrochemical stability of MnO_(2)@N cathode.In addition,the electrochemical mechanism of MnO_(2)@N cathode has been explored by the CV,GCD and GITT tests.It is found that nitrogen doping promotes the intercalation of H^(+) and the corresponding capacity contribution.Compared with the original MnO_(2) cathode,the diffusion coefficient of H^(+) and Zn^(2+) in MnO_(2)@N cathode increases.Also,the reactions during the charging and discharging process are explored through the ex-situ XRD test.And this work may provide some new ideas for improving the stability of manganese-based zinc-ion batteries. | Yanan Zhang Yanpeng Liu Zhenhua Liu Xiaogang Wu Yuxiang Wen Hangda Chen Xia Ni Guohan Liu Juanjuan Huang Shanglong Peng | 2022 | Journal of Energy Chemistry2022,31,1: | 6 |
| 13 | A New Species of the Genus Rhacophorus (Anura: Rhacophoridae) from Dabie Mountains in East China显示文摘A new species of rhacophorid of the genus Rhacophorus is described from the Dabie Mountains of west Anhui,east China.The new species,Rhacophorus zhoukaiyae sp.nov.is distinguished from its congeners by a combination of the following characters: 1) the ventral surface and front-and-rear of the femur is paler yellowish and decorated with irregular grayish blotching,and without obvious spots on the dorsum of the hand and foot webbing; 2) the outer metatarsal tubercle is small; 3) outer fingers are half-webbed and outer toes two third webbed; 4) the skin on the dorsum is smooth and without compressed warts; 5) the throat,chest and belly are pure paler yellowish; 6) the dorsal part of the fingers and toes are grayish-white; 7) the iris is golden-yellow.In addition,the phylogenetic tree showed that all the individuals of R.zhoukaiyae sp.nov.clustered into one distinct clade which suggested the validity of this species.This results could also be used to the support of species delimitation.Currently,this species is known only from mid-elevation montane evergreen forest in the Dabie Mountains of west Anhui,China. | Tao PAN Yanan ZHANG Hui WANG Jun WU Xing KANG Lifu QIAN Kai LI Yu ZHANG Jinyun CHEN Dingqi RAO Jianping JIANG Baowei ZHANG | 2017 | Asian Herpetological Research2017,18,1: | 5 |
| 14 | Rational design of phosphorus-doped cobalt sulfides electrocatalysts for hydrogen evolution显示文摘Moderate anionic doping is an effective approach to improve the performance of electrocatalysts toward hydrogen evolution reaction(HER)since it can adjust the electronic structure,activesite,and phase.The reported studies mainly focus on designing P doped C0S2,while otherphases of cobalt sulfide,such as Co1-xS and Co9S8 doped with P are rarely investigated for HER electrocatalysts.Herein,various cobalt sulfides(including CoSg/Co1-xS,Co1-xS,and Co9S8)doped with P are anchored on carbon cloth through a facile hydrothermal method.Among tested electrocatalysts,P doped Co1-xS exhibits excellent electrocatalytic performance with an overpotential of 110 and 165 mV(vs.RHE)for currentdensities of 10 and 100 mA·cm^-2,respectively.Density functional theory calculations reveal that P doped Co1-xS possesses a smaller bandgapand more optimal hydrogen adsorption sites than pristine Co1-xS.This work initially investigates various cobalt sulfides doped with P and furthergets in sight into the activity improvement mechanism of P dopi ng,which could guide the desig n of earth-abunda nt HER electrocatalysts for the'hydrogen economy'. | Guoxing Qu Tianli Wu Yanan Yu Zekang Wang Yang Zhou Zhendong Tang Qin Yue | 2019 | Nano Research2019,12,12: | 5 |
| 15 | Paleomagnetic results from Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane, Tibet, China, and their tectonic implications显示文摘Results of a systematic paleomagnetic study are reported based on Late Carboniferous to Early Permian sedimentary rocks on the north slope of the Tanggula Mountains,in the northern Qiangtang terrane(NQT),Tibet,China.Data revealed that magnetic minerals in limestone samples from the Zarigen Formation(CP^z)are primarily composed of magnetite,while those in sandstone samples from the Nuoribagaribao Formation(Pnr)are dominated by hematite alone,or hematite and magnetite in combination.Progressive thermal,or alternating field,demagnetization allowed us to isolate a stable high temperature component(HTC)in 127 specimens from 16 sites which successfully passed the conglomerate test,consistent with primary remnance.The tilt-corrected mean direction for Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane is D_s=30.2°,I_s=-40.9°,k_s=269.0,a_(95)=2.3°,N=16,which yields a corresponding paleomagnetic pole at 25.7°N,241.5°E(dp/dm=2.8°/1.7°),and a paleolatitude of 23.4°S.Our results,together with previously reported paleomagnetic data,indicate that:(1)the NQT in Tibet,China,was located at a low latitude in the southern hemisphere,and may have belonged to the northern margin of Gondwana during the Late Carboniferous to Early Permian;(2)the Paleo-Tethys Ocean was large during the Late Carboniferous to Early Permian,and(3)the NQT subsequently moved rapidly northwards,perhaps related to the fact that the Paleo-Tethys Ocean was rapidly contracting from the Late Permian to Late Triassic while the Bangong Lake-Nujiang Ocean,the northern branch of the Neo-Tethys Ocean,expanded rapidly during this time. | YANG XingFeng CHENG Xin ZHOU YaNan MA Lun ZHANG XiaoDong YAN ZhaoSheng PENG XiMing SU HaiLun WU HanNing | 2017 | Science China Earth Sciences2017,60,1: | 5 |
| 16 | Serine metabolism orchestrates macrophage polarization by regulating the IGF1–p38 axis显示文摘Serine metabolism is reportedly involved in immune cell functions, but whether and how serine metabolism regulates macrophage polarization remain largely unknown. Here, we show that suppressing serine metabolism, either by inhibiting the activity of the key enzyme phosphoglycerate dehydrogenase in the serine biosynthesis pathway or by exogenous serine and glycine restriction, robustly enhances the polarization of interferon-γ-activated macrophages (M(IFN-γ)) but suppresses that of interleukin-4-activated macrophages (M(IL-4)) both in vitro and in vivo. Mechanistically, serine metabolism deficiency increases the expression of IGF1 by reducing the promoter abundance of S-adenosyl methionine-dependent histone H3 lysine 27 trimethylation. IGF1 then activates the p38-dependent JAK–STAT1 axis to promote M(IFN-γ) polarization and suppress STAT6-mediated M(IL-4) activation. This study reveals a new mechanism by which serine metabolism orchestrates macrophage polarization and suggests the manipulation of serine metabolism as a therapeutic strategy for macrophage-mediated immune diseases. | Xiao Shan Penghui Hu Lina Ni Long Shen Yanan Zhang Zemin Ji Yan Cui Meihua Guo Haoan Wang Liyuan Ran Kun Yang Ting Wang Lei Wang Bin Chen Zhi Yao Vingjie Wu Qiujing Yu | 2022 | Cellular & Molecular Immunology2022,19,11: | 5 |
| 17 | Kinetics and mechanism of hexavalent chromium removal by basic oxygen furnace slag显示文摘Basic oxygen furnace slag(BOFS) has the potential to remove hexavalent chromium(Cr(VI))from wastewater by a redox process due to the presence of minerals containing Fe2+. The effects of the solution p H, initial Cr(VI) concentration, BOFS dosage, BOFS particle size, and temperature on the removal of Cr(VI) was investigated in detail through batch tests. The chemical and mineral compositions of fresh and reacted BOFS were characterized using scanning electron microscope(SEM) equipped with an energy dispersive spectrometer(EDS)system and X-ray diffractometer(XRD). The results show that Cr(VI) in wastewater can be efficiently removed by Fe2+released from BOFS under appropriate acidic conditions. The removal of Cr(VI) by BOFS significantly depended on the parameters mentioned above. The reaction of Cr(VI) with BOFS followed the pseudo-second-order kinetic model. Fe2+responsible for Cr(VI) removal was primarily derived from the dissolution of Fe O and Fe3O4 in BOFS. When H2SO4 was used to adjust the solution acidity, gypsum(Ca SO4·2H2O)could be formed and become an armoring precipitate layer on the BOFS surface, hindering the release of Fe2+and the removal of Cr(VI). Finally, the main mechanism of Cr(VI) removal by BOFS was described using several consecutive reaction steps. | Chong Han Yanan Jiao Qianqian Wu Wangjin Yang He Yang Xiangxin Xue | 2016 | Journal of Environmental Sciences2016,28,8: | 4 |
| 18 | Balance between education and game-play— A case study of design and optimization of the mini-game book classification显示文摘Purpose: Based on our experience of designing and testing a computer-based game for teaching undergraduate students information literacy(IL) concepts and skills, this paper summarizes the basic strategies for striking a balance between education and entertainment for the designers of quality IL games.Design/methodology/approach: The project team recruited 10 college students to play the game and post-game group interviews revealed problems and optimization priorities. The optimized game was tested among 50 college students. Based on a comparison of testing results of the two versions of the game, basic strategies for designing quality IL games were summarized.Findings: The following 5 basic strategies can effectively promote combination of education and entertainment: 1) using adventure games to enhance gaming experience, 2) plotting an intriguing story to attract players, 3) motivating players to engage in game play with game components such as challenge, curiosity, fantasy and control, 4) presenting learning materials through game props, and 5) assigning players tasks to be completed with subject knowledge.Research limitations: The 5 basic strategies have been tested only in the development process of one game, and the book classification knowledge in the mini-game is limited to the22 major categories of the Chinese Library Classification.Practical implications: University libraries may refer to our experience to design and utilize educational games to promote the IL education for college students.Originality value: Few empirical studies tested and summarized strategies for combining learning and fun in the design of IL games for university students. The 5 strategies, which are summarized in the process of design and optimization of the mini-game book classification,are valuable for other designers of IL games. | Jianhua WU Yanan CHEN Xiangtao MA | 2015 | Chinese Journal of Library and Information Science2015,,1: | 4 |
| 19 | Study of Oxygen Vacancies on Different Facets of Anatase TiO2显示文摘Anatase TiO2 samples with different ratios of {101} to {001} facets were prepared with hydrothermal method and further treated under three specific calcination atmospheres (air,H2,N2).The characterization results indicate that {001} facets may generate more oxygen vacancies and more Ti3+ species than {101} facets. | Yanan Wu Yingyi Fu Li Zhang Yuanhang Ren Xueying Chen Bin Yue Heyong He | 2019 | Chinese Journal of Chemistry2019,37,9: | 4 |
| 20 | Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies显示文摘Social hierarchies emerged during evolution,and social rank influences behavior and health of individuals.However,the evolutionary mechanisms of social hierarchy are still unknown in amniotes.Here we developed a new method and performed a genome-wide screening for identifying regions with accelerated evolution in the ancestral lineage of placental mammals,where mammalian social hierarchies might have initially evolved.Then functional analyses were conducted for the most accelerated region designated as placental-accelerated sequence 1(PAS1,P=3.15 × 10^-18).Multiple pieces of evidence show that PAS1 is an enhancer of the transcription factor gene Lhx2 involved in brain development.PAS1s isolated from various amniotes showed different c/s-regulatory activity in vitro,and affected the expression of Lhx2 differently in the nervous system of mouse embryos.PAS1 knock-out mice lack social stratification.PAS1 knock-in mouse models demonstrate that PAS1s determine the social dominance and subordinate of adult mice,and that social ranks could even be turned over by mutated PAS1.All homozygous mutant mice had normal huddled sleeping behavior,motor coordination and strength.Therefore,PAS1-Lhx2 modulates social hierarchies and is essential for establishing social stratification in amniotes,and positive Darwinian selection on PAS1 plays pivotal roles in the occurrence of mammalian social hierarchies. | Yuting Wang Guangyi Dai Zhili Gu Guopeng Liu Ke Tang Yi-Hsuan Pan Yujie Chen Xin Lin Nan Wu Haoshan Chen Su Feng Shou Qiu Hongduo Sun Qian Li Chuan Xu Yanan Mao Yong Edward Zhang Philipp Khaitovich Yan-Ling Wang Qunxiu Liu Jing-Dong Jackie Han Zhen Shao Gang Wei Chun Xu Naihe Jing Haipeng Li | 2020 | Cell Research2020,30,5: | 4 |