|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MiR-181b suppresses proliferation of and reduces chemoresistance to temozolomide in U87 glioma stem cells显示文摘MicroRNAs regulate self renewal and differentiation of cancer stem cells.There,we sought to identify the expression of miR-181b in glioma stem cells and investigate the biological effect of miR-181b on glioma stem cells in this study.MiR-181b expression was measured by real-time PCR in glioma stem cells isolated from U87 cells by FACS sorting.After miR-181b was overexpressed in U87 glioma stem cells by miR-181b lentiviral expression vector and/or treatment of temozolomide,secondary neurosphere assay,soft agar colony assay and MTT assay were performed.Compared with U87 cells,the expression of miR-181b was significantly decreased in U87 glioma stem cells.Overexpression of miR-181b decreased neurosphere formation by U87 glioma stem cells in vitro and suppressed colony formation in soft agar,and the cell growth inhibition rates increased in a time-dependent manner in U87 glioma stem cells infected with miR-181b lentivirus.Furthermore,miR-181b had a synergistic effect on temozolomide-induced inhibition of secondary neurosphere and soft agar colony,and on cell growth inhibition rates.MiR-181b functions as a tumor suppressor that suppresses proliferation and reduces chemoresistance to temozolomide in glioma stem cells. | Ping Li Xiaoming Lu Yingyi Wang Lihua Sun Chunfa Qian Wei Yan Ning Liu Yongping You Zhen Fu | 2010 | The Journal of Biomedical Research2010，24，6： | 14 |
| 2 | Study of Oxygen Vacancies on Different Facets of Anatase TiO2显示文摘Anatase TiO2 samples with different ratios of {101} to {001} facets were prepared with hydrothermal method and further treated under three specific calcination atmospheres (air,H2,N2).The characterization results indicate that {001} facets may generate more oxygen vacancies and more Ti3+ species than {101} facets. | Yanan Wu Yingyi Fu Li Zhang Yuanhang Ren Xueying Chen Bin Yue Heyong He | 2019 | Chinese Journal of Chemistry2019，37，9： | 4 |
| 3 | Growth monitoring of greenhouse lettuce based on a convolutional neural network显示文摘Growth-related traits,such as aboveground biomass and leaf area,are critical indicators to characterize the growth of greenhouse lettuce.Currently,nondestructive methods for estimating growth-related traits are subject to limitations in that the methods are susceptible to noise and heavily rely on manually designed features.In this study,a method for monitoring the growth of greenhouse lettuce was proposed by using digital images and a convolutional neural network(CNN).Taking lettuce images as the input,a CNN model was trained to learn the relationship between images and the corresponding growth-related traits,i.e.,leaf fresh weight(LFW),leaf dry weight(LDW),and leaf area(LA).To compare the results of the CNN model,widely adopted methods were also used.The results showed that the values estimated by CNN had good agreement with the actual measurements,with R^(2) values of 0.8938,0.8910,and 0.9156 and normalized root mean square error(NRMSE)values of 26.00,22.07,and 19.94%,outperforming the compared methods for all three growth-related traits.The obtained results showed that the CNN demonstrated superior estimation performance for the flat-type cultivars of Flandria and Tiberius compared with the curled-type cultivar of Locarno.Generalization tests were conducted by using images of Tiberius from another growing season.The results showed that the CNN was still capable of achieving accurate estimation of the growth-related traits,with R2 values of 0.9277,0.9126,and 0.9251 and NRMSE values of 22.96,37.29,and 27.60%.The results indicated that a CNN with digital images is a robust tool for the monitoring of the growth of greenhouse lettuce. | Lingxian Zhang Zanyu Xu Dan Xu Juncheng Ma Yingyi Chen Zetian Fu | 2020 | Horticulture Research2020，7，1： | 2 |
| 4 | Effects of Application of Cassava Alcohol Anaerobic Fermentation Liquid and Mulching of Film on Overwintering and Next Year's Growth and Yield of Banana显示文摘The effects of application of cassava alcohol anaerobic fermentation liquid and mulching of film on overwintering and next year's growth and yield of banana were investigated in this study.The results showed that the application of cassava alcohol anaerobic fermentation liquid with COD concentration of 1 200-2 000 mg/L(900 m^3/hm^2) and mulching of film significantly increased the soil organic matter and available potassium contents in banana orchard,improved the cold resistance of banana seedlings,increased the pseudostem height,pseudostem circumference,green leaf number and chlorophyll content of next year's banana seedlings,brought the flower bud emergence period and harvest period forward,and significantly increased the yield per plant. | Yunchuan MO Yingyi DENG Xu ZHENG Yixin YE Ganhui MO Minzheng WEI Weiliu LI Feng LI Jiechun PAN Chanchan QIN Meiling SU Yao FU | 2016 | Agricultural Science & Technology2016，17，7： | 2 |
| 5 | Influencing factors of colostrum exposure to low-level lead and their relationship with early neural development of infants显示文摘BACKGROUND: Exposure to low-level lead has a toxic effect on the development of neonates, which has attracted wide attention. Colostrum lead level can be used as the indication of lead exposure. OBJECTIVE: To observe the relationship of colostrum lead level and the neurobehavioral development of infants. DESIGN: A prospective control observation. SETTING: Center for Maternal and Child Health, Shanxi Provincial Children's Hospital. PARTICIPANTS: Totally 128 neonates of full-term normal delivery, 76 male and 52 female, from Shanxi Provincial Maternal and Child Health Center and Jiexiu Maternal and Child Health Center were involved in this study. All the involved neonates had no peripartal ischemic/hypoxic history or fetus intrauterine developmental lag. Pregnant women had no various acute and chronic diseases in pregnancy, family history of neurological disease or occupational lead exposure. 128 portions of colostrum sample of full-term normal delivery were collected. Informed consents of detected items were obtained from the puerperants and their relatives. METHODS: ① Experimental grouping: Lead level in the colostrum was determined by atomic absorption spectrometry. According to lead level in the colostrum, the neonates were classified into two exposure groups of greater than or equal to 0.24 μmol/L in a high-level lead group and less than 0.24 μ mol/L in a low-level lead group. ② Experimental evaluation: Mental developmental index (MDI) and psychological developmental index (PDI) of 3-month-old infants were evaluated with Bayley Scales of Infant Development (BSID). The relationships of MDI, PDI and colostrum lead level were performed correlation regression analysis; The relationship of colostrum lead level and development was performed multi-factor analysis with family environment and health questionnaires. MAIN OUTCOME MEASURES: ① Evaluation results of MDI and PDI. ② Multi-factor analysis results. RESULTS: Totally 128 neonates were involved in the study. Ten and eleven neonates were lost due to emigration in the high-level lead group and low-level lead group respectively, and the other 107 neonates participated in the final analysis. ① MDI and PDI in the high-level lead group were significantly lower than those in the low-level lead group, respectively (P < 0.01); Regression analysis results showed that two developmental indexes were statistically negatively correlated with colostrum lead level (regression equation y = 1.9+0.01x1,-0.04x2,+0.04x3,+0.03x4). ② Four variables of the factors included by family environment and health questionnaires were taken into equation. Large maternal age, irrational dietary pattern in pregnancy and pollution degree of habitation environment in pregnancy were the risk factors of colostrum lead level (partial regression coefficien t =0.598 4,0.426 8,0.306 7,P < 0.05-0.01), and calcium supplementation in pregnancy was a protective factor (partial regression coefficien t =-0.455 8, P < 0.01). CONCLUSION: High colostrum lead level will have adverse effects on the early development of neonates; Large maternal age, irrational dietary pattern in pregnancy and pollution degree of habitation environment in pregnancy are the risk factors of colostrum lead level, and calcium supplementation in pregnancy was a protective factor. | Shiguang Li Guoping Wang Kui Fu Chunru Qi Xianguo Wu Qinghao Kong Yingyi Liang | 2007 | Neural Regeneration Research2007，2，9： | 1 |
| 6 | Privacy Preserving Serial Data Publishing By Role Composition显示文摘 | Yingyi Bu Ada Wai-Chee Fu Raymond Chi-Wing Wong Lei Chen Jiuyong Li | 2008 | Proceedings of the VLDB Endowment2008，1，1： | 1 |
| 7 | Porcine interleukin-2 gene encapsulated in chitosan nanoparticles enhances immune response of mice to piglet paratyphoid vaccine显示文摘 | Yi Yang Jianlin Chen Hui Li Yingyi Wang Zhao Xie Mei Wu Huan Zhang Zhongzhong Zhao Qian Chen Manliang Fu Kaiyuan Wu Cheng Chi Hongning Wang Rong Gao | 2006 | Comparative Immunology Microbiology and Infectious Diseases2006，，1： | 1 |
| 8 | Analysis of amino acid enantiomers in ambient aerosols:Effects and removal of coexistent aerosol matrix显示文摘Amino acids(AAs)including D-and L-enantiomers are a group of organic nitrogen species in ambient aerosol.Due to the low abundances of AAs(level of ng/m^(3))and the matrix effects by coexistent components,it is challenging to quantify AA enantiomers in ambient aerosols especially under pollution conditions.In this study,we present an optimized method for analyzing AA enantiomers in atmospheric aerosol samples including a pretreatment process and the detection by high performance liquid chromatography coupled to a fuorescence detector(HPLC-FLD).Matrix effects caused by coexistent chemicals on AA enantiomers analysis in ambient aerosol samples were investigated especially for those collected in pollution episodes.The results revealed that the determination of AA enantiomers is significantly affected by the coexistent organic carbon(as a proxy of organic matter)and water-soluble ion of NH_(4)^(+).To remove the matrix effects,we applied a pretreatment using the solid phase extraction column coupled with alkaline adjustment to sample extract.After pretreatment,18 AAs including 6 pairs of D-and L-enantiomers(i.e.,leucine,isoleucine,valine,alanine,serine,and aspartic acid)can be successfully separated and quantified in aerosol samples by HPLC-FLD.The recoveries are in the range of 67%-106%.This method was successfully applied to the urban aerosol samples from pollution and non-pollution periods for AA enantiomers determination.We suggest that the concentrations of D-AAs and the ratio of D-AA/L-AA are indicative of the contribution of bacterial sources and the infuence of biomass burning. | Ying Li Xiaoying Li Libin Wu Luhan Shi ShanWang Pingqing Fu Yingyi Zhang Senchao Lai | 2024 | Journal of Environmental Sciences2024，，3： | 0 |
| 9 | Promotional effect of cerium on nickel-containing mesoporous silica for carbon dioxide reforming of methane显示文摘A series of Ce-promoted 6.7%Ni-containing mesoporous silica(Ce-Ni-Si O2)with varying Ce content(0.5%–4.8%)was prepared using the evaporation-induced self-assembly method.The characterization results showed that Ce and Ni species were homogeneously incorporated into the mesoporous silica matrix.The catalytic properties of these samples in the dry reforming of methane reaction revealed that the catalysts(e.g.,1.2%Ce-Ni-Si O2)containing highly dispersed small Ni particles exhibited excellent catalytic activity and long-term stability,which is attributed to the anchoring effect of the Ce and its ability to increase surface oxygen species concentration. | Yingyi Fu Yanan Wu Wenjia Cai Bin Yue Heyong He | 2015 | Science China Chemistry2015，58，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员