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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 3 | Strengthening the Interna-tional Health Regulations:lessons from the H1N1 pandemic显示文摘 | Wilson K Brownstein JS Fidler DP | | Health Policy Plan0，25，6： | 1 |
| 4 | Development of adverse sequelae in children born with subclinicalcongenital Toxoplasma infection显示文摘 | Wilson CB Remington JS Stagno S Reynolds DW | 1980 | Pediatrics1980，66，： | 1 |
| 5 | Single injections of vascular endothelial growth factor trap block ovulation in the macaque and produce a prolonged,dose-related suppression of ovarian function显示文摘 | Fraser HM Wilson H Rudge JS | 2005 | Journal of Clinical Endocrinology & Metabolism2005，90，2： | 1 |
| 6 | Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system显示文摘 | Stumhofer JS Laurence A Wilson EH | 2006 | Nat Immunol2006，7，： | 1 |
| 7 | Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system显示文摘 | Stumhofer JS Laurence A Wilson EH | 2006 | Nat Immunol2006，7，9： | 1 |
| 8 | The wound healing response afar laser in situ keratomileusis and photorefractive keratectomy: elusive contral of biological variability and effect on custom laser vision correction显示文摘 | Wilson SE Mohan RR Hong JW Lee JS Choi R Mohan RR | 2001 | Arch Ophthalmol2001，119，6： | 1 |
| 9 | Muscle hernination: a complication at the anteroIateral thigh perforator flap donor site显示文摘 | Odili J Wilson E Chana JS | 2009 | J Plast Reconstr Aesther Surg2009，62，11： | 1 |
| 10 | Does additional support by nurses enhance the effect of a brief smoking cessation intervention in people with moderate to severe chronic obstructive pulmonary disease? A randomised controlled trial显示文摘 | Wilson JS Fitzsimons D Bradbury I | | 0，，04： | 1 |
| 11 | Pancreatic stellate ceils: a starring role in normal and diseased pancreas 显示文摘 | APTE MV PIROLA RC WILSON JS | 2012 | Frontiers in Physiology2012，，3： | 1 |
| 12 | Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system 显示文摘 | Stumhofer JS Laurence A Wilson EH Huang E Tato CM Johnson LM | 2006 | Nat Immunol2006，7，9： | 1 |
| 13 | Chronic pancreatitis:complications and management显示文摘 | Apte MV Keogh Gw Wilson JS | 1999 | JClin Gastroenterol1999，29，3： | 1 |
| 14 | Alcohol-induced pancreatic injury显示文摘 | Apte MV Wilson JS | 2008 | BestPratt Res Clin Gastroenterol2008，27，4： | 1 |
| 15 | A qualitative tool for critical think- ing skill development显示文摘 | Cise JS Wilson CS Thie MJ | 2004 | Nurse Educ2004，29，4： | 1 |
| 16 | The buih environment and location-based physical activity 显示文摘 | Troped PJ Wilson JS Matthews CE | 2010 | Am J Prey Med2010，38，4： | 1 |
| 17 | Macrophage ABCAIreduces MyD88-dependent Toll-like receptor trafficking to lipidrafts by reduction of lipid raft cholesterol 显示文摘 | Zhu X Owen JS Wilson MD | 2010 | J Lipid Res2010，51，： | 1 |
| 18 | Flexible dietchoice offsets protein costs of pathogen resistance in a caterpillar 显示文摘 | Lee KP Cory JS Wilson K | 2006 | Proceedingsof the Royal Society B: Biological Sci- ences2006，273，： | 1 |
| 19 | A qualitative tool for critical thinking skill development 显示文摘 | Cise JS Wilson CS Thie MJ | 2004 | Nurse Educ2004，29，4： | 1 |
| 20 | A comparison of renal damage induced by varying modes of shock wave generation 显示文摘 | Morris JS Husmann DA Wilson WT | 1991 | J Urol1991，145，4： | 1 |
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