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1High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6.Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders 2016Horticulture Research2016,3,1:6
2显示文摘Godlewski P Mazurkiweicz T Weg~owski R 2004Neurol Neuroehir Pol2004,38,5:1
3The bauplan of the Urmetazoa:the basis of the genetic complexity of Metazoa-using the siliceous sponges(Porifera) as living fossils显示文摘Müller WEG Wiens M Adell T 2004Int Rev Cytol2004,235,:1
4Fitting the Stillinger-Weber potential to amorphous silicon显示文摘 BARKEMA G T van der WEG W F 2001Journal of Non-crystalline Solids2001,282,23:1
5Genome-Wide SNP detection,validation,and development of an 8K SNP array for apple显示文摘Chagne D Crowhurst R N Troggio M Davey M W Gilmore B Lawley C Vanderzande S Hellens R P Kumar S CestaroA Velasco R Main D Rees J D Iezzoni A Mockler T Wilhelm L Van de Weg E Gardiner S E Bassil N Peace C 0,,:1
6Genetic analysis of metabolites in apple fruits indicates an mQTL hotspot for phenolic compounds on linkage group 16显示文摘Khan S A Chibon P Y de Vos R C H Schipper B A Walraven E Beekwilder J van Dijk T Finkers R Visser R G van de Weg E W Bovy A Cestaro A Velasco R Jacobsen E Schouten H J 0,,:1
7Antithrombotic therapy for venous thromboembolic disease显示文摘Hyers T M Hull R D Weg J G 1992Chest1992,102,5:1
8Genetic linkage maps of Japanese and European pear aligned to the apple consensus map显示文摘YAMAMOTO T KIMURA T SAITO T KOTOBUKI K MATSUTA N LIEBHARD R GESSLER C VAN DE WEG W E HAYASHI T 2004Acta Horticuhurae2004,663,:1
9Genetic linkage maps of Japanese and European pear aligned to the apple consensas map显示文摘YAMAMATO T KIMURA T SAITO T KOTOBUKI K MATSUATA N LIEBHARD R GESSLER C VAN DE WEG W E HAYASGI T 2004Acta Hort2004,663,:1
10Genetic linkage maps of Japanese and European pear aligned to the apple consensus map显示文摘YAMAMOTO T KIMURA T SAITO T KOTOBUKI K MATSUTA N LIEBHARD R GESSLER C VAN DE WEG W E HAYASHI T 2004Acta Horti2004,663,1:1
11Ramanspectra and structure of amorphous Si显示文摘Vink R L C Barkema C T W F van der Weg 2001Physical Review B2001,63,11:1
12Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guineapig skin 显示文摘SANZ M J WEG V B WALSH D T 1994Br J Pharmacol1994,113,2:1
13Genetic linkage maps of Japanese and European pears aligned to the apple consensus map显示文摘YAMAMOTO T KIMURA T SAITO T KOTOBUKI K MATSUTA N LIEBHARD R GESSLER C WEG W E VAN DE HAYASHI T 2004Acta Hort2004,663,:1
14Genetic linkage maps of Japanese and European pears aligned to the apple consensus map显示文摘YAMAMOTO T KIMURA T SAITO T KOTOBUKI K MATSUTA N LIEBHARD R GESSLER C VAN DE WEG W E HAYASHI T 2004Acta Hort2004,663,1:1
15Resolution of Crohn's disease and complex regional pain syndrome following treatment of paratuberculosis显示文摘A cohort of family members with various chronic diseases including Crohn's disease, asthma, complex regional pain syndrome, hypothyroidism, type 1 diabetes mellitus, and lymphangiomatosis and/or evidence of infection by Mycobacterium avium subsp. paratuberculosis(MAP) are described in this series of case reports. MAP was cultured from the blood of three members affected by the first five diseases and there was accompanying elevated anti-MAP Ig G in two members. The patient affected by the sixth disease has a markedly elevated anti-MAP titer. The two patients affected by the first four diseases have been treated with a combination of anti-MAP antibiotics and ultraviolet blood irradiation therapy with resolution of the disease symptomatology and inability to culture MAP in post treatment blood samples. These case reports of patients with MAP infections provide supportive evidence of a pathogenic role of MAP in humans.J Todd Kuenstner William Chamberlin Saleh A Naser Michael T Collins Coad Thomas Dow John M Aitken Stuart Weg Grzegorz Telega Kuruvilla John David Haas Torsten M Eckstein Maher Kali Christine Welch Thomas Petrie 2015World Journal of Gastroenterology2015,21,13:0
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