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| 1 | 外源茉莉酸对大豆中异戊烯黄酮Glyceollins及其前体Glycinol累积的影响显示文摘以中黄13号大豆种子为材料,取生长8天的健康子叶,在其表面挖出约2×2mm的伤口,将50μl不同浓度的茉莉酸溶液和1mM的硝酸银溶液滴在伤口处,黑暗中(25℃)保温不同时间后取样,经甲醇提取,用高压液相色谱(HPLC)测定其中异戊烯化异黄酮glyceollins及其前体glycinol 的累积情况.结果显示,健康子叶中没有glyceollins和glycinol的累积,1mM硝酸银比茉莉酸具有更强的诱导glyceollins和glycinol累积的能力,glyceollins的累积与茉莉酸浓度呈负相关.在各种处理中,glyceollinⅠ、Ⅱ、Ⅲ所占比例分别为:50%~80%、10%~40%和10%~20%,但是glyceollin三种异构体的比例随保温时间的延长而有所变化,glyceollin Ⅰ比例逐渐下降,glyceollin Ⅱ所占比例逐渐升高,在1mM硝酸银处理的子叶中表现更为明显. | 乞永艳 Arnaud Bovy Ricde Vos 唐益雄 | 2005 | 大豆科学2005，24，4： | 7 |
| 2 | 异源表达细菌二氢喋呤合成酶基因提高拟南芥叶酸含量的研究显示文摘植物是人体叶酸的重要来源,人体缺乏叶酸会导致贫血、新生儿神经系统疾病,还与心血管病及某些癌症的发病有关,因此提高食用作物中叶酸的含量是代谢工程的研究目标之一。本研究将从细菌中分离到的编码二氢喋呤合成酶(DHPS)基因FolP,由35S启动子驱动在拟南芥线粒体中过量表达,获得了转基因植株。转基因植株叶酸总含量比野生型对照提高48%,表明DHPS酶对植物叶酸的合成起着调控作用。 | 梁业红 Arnaud Bovy 范云六 | 2006 | 作物学报2006，32，2： | 6 |
| 3 | Overlap syndrome consisting of PSC-AIH with concomitant presence of a membranous glomerulonephritis and ulcerative colitis显示文摘The association of primary sclerosing cholangitis(PSC)and autoimmune hepatitis(AIH)is known as an overlap syndrome(OS).OS can also be described in the setting of concomitant presence of AIH and PSC.These diseases can in some cases be associated with ulcerative colitis.In this case report we describe,to our knowledge,the first case in the literature of a young Caucasian male suffering from ulcerative colitis and an overlap syndrome consisting of an association betweenPSC-AIH,with the concomitant presence of a membranous glomerulonephritis. | Odile Warling Christophe Bovy Carla Combra Timothée Noterdaeme Jean Delwaide Edouard Louis | 2014 | World Journal of Gastroenterology2014，20，16： | 4 |
| 4 | CD 64 distinguishes macrophages from dendritic cells in the gut and reveals the T h1‐inducing role of mesenteric lymph node macrophages during colitis显示文摘 | Samira Tamoutounour Sandrine Henri Hugues Lelouard Béatrice de Bovis Colin de Haar C. Janneke van der Woude Andrea M. Woltman Yasmin Reyal Dominique Bonnet Dorine Sichien Calum C. Bain Allan McI. Mowat Caetano Reis e Sousa Lionel F. Poulin Bernard Malisse | 2012 | Eur J Immunol2012，，12： | 2 |
| 5 | 外源茉莉酸对大豆异黄酮的影响显示文摘摘下生长8天的大豆子叶,在不同浓度茉莉酸溶液中浸泡一定时间,用甲醇提取大豆异黄酮,经高压液相色谱(HPLC)测定,研究子叶表面伤口、浸泡时间以及茉莉酸浓度对大豆异黄酮的影响。结果显示:在对照组(0.1%乙醇),子叶表面的伤口不影响异黄酮的分配比例;而用茉莉酸浸泡组,健康子叶中几乎不存在游离型的大豆甙元和染料木黄酮;丙二酰大豆甙和丙二酰染料木甙所占比例随着浸泡时间的延长而下降,大豆甙元和染料木黄酮所占比例随浸泡时间的延长而增加,大豆甙和染料木甙所占比例不随浸泡时间而变化;20μM茉莉酸溶液浸泡的子叶中异黄酮总量最低。 | 乞永艳 Arnaud Bovy 唐益雄 | 2006 | 大豆科学2006，25，1： | 2 |
| 6 | The gut-liver axis as a target of liver disease management显示文摘The interplay between the gut and liver,the so called“gut-liver axis”(GLA),plays a significant role in health and disease.As shown in Figure 1,the GLA is regulated by a number of equally relevant interacting factors including gut microbiota,integrity and function of the intestinal wall,antigen trafficking,mucosal innate immune response,and oxidative stress(1,2).In addition to undigested or unabsorbed food and microorganisms,the gut lumen contains also their fermentation/metabolic products,bile,mucus,and epithelial cells spontaneously exfoliated from the gastrointestinal mucosa.The latter is composed of various cell types counting immune cells,goblet cells,and enterocytes strongly connected by tight junctions and covered with a mucus layer that acts as a dynamic barrier.Recent elucidation of a gut-vascular barrier(GVB)has revealed this structure to intervene to control gut bacteria and antigen translocation from the gut into the blood stream(3).Interestingly,diseases that are characterized or aggravated by impairment of the barrier function(so-called“leaky gut”)and/or particular patterns of the microbiome(e.g.,a lack of balance between Bacteroides and Firmicutes)are not restricted to the intestinal tract and liver.Some relevant examples are represented by diabetes type 1,familial Mediterranean fever,obesity,cardiovascular disease,decreased bone-mass density,autism,dysregulation of immune response and systemic allergic diseases(1). | Claudia Mandato Anna Pia Delli Bovi Pietro Vajro | 2021 | Hepatobiliary Surgery and Nutrition2021，10，1： | 2 |
| 7 | Use of ketamine sedation for the management of displaced paediatric forearm fractures显示文摘AIM To determine if ketamine sedation is a safe and cost effective way of treating displaced paediatric radial and ulna fractures in the emergency department. METHODS Following an agreed interdepartmental protocol, fractures of the radius and ulna(moderately to severely displaced) in children between the age of 2 and 16 years old, presenting within a specified 4 mo period, were manipulated in our paediatric emergency department. Verbal and written consent was obtained prior to procedural sedation to ensure parents were informed and satisfied to have ketamine. A single attempt at manipulation was performed. Pre and postmanipulation radiographs were requested and assessed to ensure adequacy of reduction. Parental satisfaction surveys were collected after the procedure to assess the perceived quality of treatment. After closed reduction and cast immobilisation, patients were then followed-up in the paediatric outpatient fracture clinic and functional outcomes measured prospectively. A cost analysis compared to more formal manipulation under a general anaesthetic was also undertaken.RESULTS During the 4 mo period of study, 10 closed, moderate to severely displaced fractures were identified and treated in the paediatric emergency department using our ketamine sedation protocol. These included fractures of the growth plate(3), fractures of both radius and ulna(6) and a single isolated proximal radius fracture. The mean time from administration of ketamine until completion of the moulded plaster was 20 min. The mean time interval from sedation to full recovery was 74 min. We had no cases of unacceptable fracture reduction and no patients required any further manipulation, either in fracture clinic or under a more formal general anaesthetic. There were no serious adverse events in relation to the use of ketamine. Parents, patients and clinicians reported extremely favourable outcomes using this technique. Furthermore, compared to using a manipulation under general anaesthesia, each case performed under ketamine sedation was associated with a saving of ￡1470, the overall study saving being ￡14700. CONCLUSION Ketamine procedural sedation in the paediatric population is a safe and cost effective method for the treatment of displaced fractures of the radius and ulna, with high parent satisfaction rates. | Anatole Vilhelm Wiik Poonam Patel Joanna Bovis Adele Cowper Philip Socrates Pastides Alison Hulme Stuart Evans Charles Stewart | 2018 | World Journal of Orthopedics2018，9，3： | 2 |
| 8 | Modification of flavonoid biosynthesis in crop plants显示文摘 | Elio G.W.M. Schijlen C.H. Ric de Vos Arjen J. van Tunen Arnaud G. Bovy | 2004 | Phytochemistry2004，，19： | 2 |
| 9 | Increasing an tioxidant levels in tomatoes through modification of the flavonoid biosynthetic pathway 显示文摘 | Verhoeyen M E Bovy A Collins G | 2002 | J Exp Bot2002，53，： | 1 |
| 10 | Cloning and expressionanalysis of cDNAs corresponding to genes activated in cu- cumber showing systemic acquired resistance after BTH treatment显示文摘 | Bovie C Ongena M Thonart P | 2004 | BMC Plant Biology2004，4，： | 1 |
| 11 | Corticotomy-enhanced intrusion of an overerupted molar using skeletal anchorage and ultrasonic surgery显示文摘 | Grenga V Bovi M | 2013 | J Clin Orthod2013，47，1： | 1 |
| 12 | Reversing the selectivity of cyclodextrin bisimidazole ribonuclease mimics by changing the catalyst geometry 显示文摘 | Bovy P Hersh C L | 1980 | J Am Chem Soc1980，102，6： | 1 |
| 13 | Quantitative methyl- ation profiling in tumor and matched morphologically normal tissues from breast cancer patients显示文摘 | Van der Auwera I Bovie C Svensson C | 2010 | BMC Cancer2010，10，： | 1 |
| 14 | Increasing antioxidantlevels in tomatoes through modification of the flavonoidbiosynthetic pathway 显示文摘 | Verhoeyen M Bovy A Collins G | 2002 | Journal of Experimental Botany2002，53，377： | 1 |
| 15 | Identification of parameters for a prospect theory model for travel choice analysis显示文摘 | Avineri E Bovy P H L | | 0，，： | 1 |
| 16 | MicroRNA-21 exhibits antiangiogenic function by tar- geting RhoB expression in endothelial cells 显示文摘 | Sabatel C Malvaux L Bovy N Deroanne C Lambert V Gonzalez ML | 2011 | PLoS ONE2011，6，16： | 1 |
| 17 | Factors determining the percentage of hypochromic red blood cells in hemodialysis patients显示文摘 | TSOBO C CRAPANZANO L | 1999 | Kidney Int1999，56，： | 1 |
| 18 | The July 1998 debris flow and landslide dam at Capricorn Creek, Mount Meager Volcanic Complex, southern Coast Mountains,British Columbia显示文摘 | Bovis M Jakob M | 2000 | Can J Earth Sci2000，37，10： | 1 |
| 19 | External validationof the SEDAN score for prediction of intracerebral hemorrhagein stroke thrombolysis显示文摘 | MAZYA M V BOVI P CASTILLO J | 2013 | Stroke2013，44，6： | 1 |
| 20 | The dermis contains langerin+dendritic cells that develop and function independently of epidermal Langerhans cells 显示文摘 | Poulin LF Henri S de Bovis B Devilard E Kissenpfennig A Malissen B | 2007 | J Exp Med2007，204，13： | 1 |
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