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| 1 | Apoptosis commitment- translating survival signals into decisions on mitochondria显示文摘最有缺点、讨厌的房间由 apoptosis 死,为没有损坏包围织物,移开如此的房间的一个精致地控制的基因计划。一旦一个房间承诺了 apoptosis,这个过程是显著地有效的,并且在开始的一些分钟以内被完成。为一个 apoptotic 房间的没有回来的这个点通常被坚持是外部 mitochondrial 膜是 permeabilised 的在点,一个过程由蛋白质的 Bcl-2 家庭调整了。这些蛋白质怎么调整这个决定点,对象 apoptotic 控制被失去的癌症那样的疾病中央。在这评论,我们将讨论 apoptotic 发信号并且一个房间怎么做不可逆的决定死。我们将集中于幸存信号,对细胞外的矩阵(ECM ) 的房间粘附导出的那些,和使用的一个集合这些加亮 apoptotic 发信号的复杂性。特别地,我们将说明多重发信号小径怎么收敛决定批评房间命运决定。 | James A Keeble Andrew P Gilmore | 2007 | Cell Research2007，17，12： | 4 |
| 2 | Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes显示文摘Fas/CD95 表面受体调停各种各样的房间的快速的死亡打字,包括有为触发 autoimmunity 的潜力的 autoreactive T 房间。这里,我们表明那的船边交货的现在的新奇方面定义一种“社会”的尺寸到导致受体的 apoptosis。船边交货刺激很快导致在附近的 T 房间之间的广泛的膜 nanotube 形成。这极其依赖于 Rho GTPases 然而并非在 caspase 激活上。包括活跃 caspases 的膜和 cytosolic 元素的双向转移能被观察经由这些 nanotubes 发生。Nanotube 形成和死亡信号的细胞间的交换在从有在船边交货受体的自体免疫的 lymphoproliferative 症候群 harbouring 变化的病人的 T 淋巴细胞是有缺点的。我们断定调停 nanotube 的交换组成扩充在附近的 T 房间之间发信号的死亡的繁殖的细胞间的通讯的一种新奇形式。 | Peter D Arkwright Francesca Luchetti Julien Tour Charlotte Roberts Rahna Ayub Ana P Morales Jose J Rodriguez Andrew Gilmore Barbara Canonico Stefano Papa Mauro Degli Esposti | 2010 | Cell Research2010，20，1： | 4 |
| 3 | Transparent conducting aluminum- doped zinc oxide thin films for organic light- emitting devices 显示文摘 | Kim H Gilmore C M Horwitz J S | 2000 | Appl Phys Lett2000，76，3： | 2 |
| 4 | A linear programming approach to the cutting-stock problem 显示文摘 | Gilmore P C Gomory R E | 1961 | Operations Research1961，，9： | 2 |
| 5 | Paediatric retinal detachment:aetiology,characteristics and outcomes显示文摘AIM: To provide contemporary data on the aetiology, clinical features and outcomes of paediatric retinal detachment.METHODS: A retrospective review of all those under 16 y who underwent surgical repair for retinal detachment at a single centre between the years 2008 and 2015 inclusive was performed. In each case the cause of retinal detachment, the type of detachment, the presence or absence of macular involvement, the number and form of reparative surgeries undertaken, and the surgical outcome achieved was recorded.RESULTS: Twenty-eight eyes of 24 patients, 15(62.5%) of whom were male and 9(37.5%) of whom were female, their mean age being 11.6 y and range 2-16y developed retinal detachment over the eight year period studied. Trauma featured in the development of retinal detachment in 14(50.0%) cases. Retinal detachment was associated with other ocular and/or systemic conditions in 11(39.3%) cases. A mean of 3.0 procedures with a range of 1-9 procedures per patient were undertaken in the management of retinal detachment. Complex vitrectomy combined with scleral buckling or complex vitrectomy alone were those most frequently performed. Mean postoperative visual acuity was 1.2 log MAR with range 0.0-3.0 log MAR. In 22 of 26(84.6%) cases which underwent surgical repair the retina was attached at last follow-up.CONCLUSION: Aggressive management of paediatric retinal detachment including re-operation increases the likelihood of anatomical success. In cases where the retinal detachment can be repaired by an external approach alone there is a more favourable visual outcome. | Elizabeth McElnea Kirk Stephenson Sarah Gilmore Michael O'Keefe David Keegan | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 2 |
| 6 | The role of hyperglycemia in acute ischemic stroke 显示文摘 | GILMORE R M STEAD L G | 2006 | Neurocrit Care2006，5，2： | 1 |
| 7 | Introduction to NF-KB: players, pathways, perspectives 显示文摘 | Gilmore T D | 2006 | Oncogene2006，25，： | 1 |
| 8 | Towards Arabidopsis genome analysisz monitoring expression profiles of 1400 genes using cDNA microarrays显示文摘 | Ruan Y J Gilmore J Conner T | 1998 | The Plant Journal1998，，6： | 1 |
| 9 | Topological analysis and synthesis of chaotic time series显示文摘 | Mindlin GB Gilmore R | 1992 | Physica D1992，，58： | 1 |
| 10 | Quantitative AES Ⅶ-the ionization cross-section in AES显示文摘 | Seah M P Gilmore I S | 1998 | Surf Interface Anal1998，26，： | 1 |
| 11 | Crown architecture of Abies balsamea from four canopy positions显示文摘 | GILMORE D W SEYMOUR R S | 1997 | Tree Physiol1997，17，： | 1 |
| 12 | Optimal and suboptimal algorithms for the quadratic assignment problem显示文摘 | Gilmore P C | 1962 | SIAM Journal on Applied Mathematics1962，10，： | 1 |
| 13 | Developmental expression of Bcl-2 protein in human cortex显示文摘 | JARSKOG L F GILMORE J H | 2000 | Brain Res Dev Brain Res2000，119，2： | 1 |
| 14 | DNA polymorphism in the conserved 190 kDa antigen gene repeat region among spotted fever group Rickettsiae 显示文摘 | Gilmore R D Jr Hackstadt T | 1991 | Biochim Biophys Acta1991，1097，1： | 1 |
| 15 | Transcription factor cross-talk:the estrogen receptor and NF-kappaB显示文摘 | Kalaitzidis D Gilmore T D | | 0，，02： | 1 |
| 16 | Best practices in diagnostic immunohistochemistry: myoepithelial markers in breast pathology显示文摘 | Dewar R Fadare O Gilmore H | 2011 | Arch Pathoi Lab Med2011，135，4： | 1 |
| 17 | Autotrophic nitrogenremoval in a membrane-aerated biofilm reactor under continuousaeration : a demonstration 显示文摘 | Gilmore K R Terada A Smets B F ef al | 2013 | Environmental EngineeringScience2013，30，1： | 1 |
| 18 | Somatic cell counts in DHI samples显示文摘 | Eberhart R J Gilmore H C Hutchinson L J | 1979 | Proc Natl Mastitis Counc1979，68，： | 1 |
| 19 | Trauma scoring systems显示文摘 | DEBRA ANN GILMORE | 1999 | Trauma Secrets1999，2，： | 1 |
| 20 | Direct electron crystallographic determination of zeolite zonal structures显示文摘 | Dorset D L Gilmore C J Jorda J L Nicolopoulos S | 2007 | Ultramicroscopy2007，107，： | 1 |
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