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| 1 | Cardiac rehabilitation and exercise therapy in the elderly: Should we invest in the aged?显示文摘冠的心疾病(CHD ) 是世界范围的死亡的领先的原因并且在病人之中变得逐渐地流行 65 岁以上。老病人在为复杂并发症的更高的风险并且在一个心血管的事件以后加速物理 deconditioning,特别与他们的更年轻的对应物相比。最后几十年是到与 CHD 在病人之中在死亡,锻练能力,心理风险因素,发炎,和肥胖上表明了心脏的康复(CR ) 和锻练治疗的有益的效果的多重研究的厕所。不幸地,这个领域里的可得到的数据的重要部分与更年轻的病人相关。可行解释是更老的病人在为以病人开始并且延长到医生的多重原因的这些节目是非常未被充分代表的。在这篇文章,我们将考察 CR 节目的好处在之中老,以及一些妨碍他们的参予的障碍。 | Arthur R Menezes Carl J Lavie Richard V Milani Ross A Arena Timothy S Church | 2012 | Journal of Geriatric Cardiology2012，9，1： | 25 |
| 2 | Primary phacoemulsification for uncontrolled angle-closure glaucoma 1 1 None of the authors has a financial or proprietary interest in any material or method mentioned.显示文摘 | Timothy V Roberts Ian C Francis Sam Lertusumitkul Medduma B Kappagoda Minas T Coroneo | 2000 | Journal of Cataract & Refractive Surgery2000，，7： | 3 |
| 3 | MicroRNA profile in neosquamous esophageal mucosa following ablation of Barrett's esophagus显示文摘AIM To investigate the micro RNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus.METHODS High throughput screening using Taq Man~ Array Human Micro RNA quantitative PCR was used to determine expression levels of 754 micro RNAs in distal esophageal mucosa(1 cm above the gastro-esophageal junction) from 16 patients who had undergone ablation of non-dysplastic Barrett's esophagus using argon plasma coagulation vs pretreatment mucosa, posttreatment proximal normal non-treated esophageal mucosa, and esophageal mucosal biopsies from 10 controls without Barrett's esophagus. Biopsies of squamous mucosa were also taken from 5 cm above the pre-ablation squamo-columnar junction. Predicted m RNA target pathway analysis was used to investigate the functional involvement of differentially expressed micro RNAs.RESULTS Forty-four micro RNAs were differentially expressed between control squamous mucosa vs post-ablation neosquamous mucosa. Nineteen micro RNAs were differentially expressed between post-ablation neosquamous and post-ablation squamous mucosa obtained from the more proximal non-treated esophageal segment. Twelve microRNAs were differentially expressed in both neosquamous vs matched proximal squamous mucosa and neosquamous vs squamous mucosa from healthy patients. Nine micro RNAs(mi R-424-5p, mi R-127-3p, mi R-98-5p, mi R-187-3p, mi R-495-3p, mi R-34c-5p, mi R-223-5p, mi R-539-5p, mi R-376a-3p, mi R-409-3p) were expressed at higher levels in post-ablation neosquamous mucosa than in matched proximal squamous and healthy squamous mucosa. These micro RNAs were also more highly expressed in Barrett's esophagus mucosa than matched proximal squamous and squamous mucosa from controls. Target prediction and pathway analysis suggests that these micro RNAs may be involved in the regulation of cell survival signalling pathways. Three micro RNAs(mi R-187-3p, mi R-135b-5p and mi R-31-5p) were expressed at higher levels in postablation neosquamous mucosa than in matched proximal squamous and healthy squamous mucosa. These mi RNAs were expressed at similar levels in preablation Barrett's esophagus mucosa, matched proximal squamous and squamous mucosa from controls. Target prediction and pathway analysis suggests that these micro RNAs may be involved in regulating the expression of proteins that contribute to barrier function.CONCLUSION Neosquamous mucosa arising after ablation of Barrett's esophagus expresses micro RNAs that may contribute to decreased barrier function and micro RNAs that may be involved in the regulation of survival signaling pathways. | Loveena Sreedharan George C Mayne David I Watson Timothy Bright Reginald V Lord Alfiya Ansar Tingting Wang Jakob Kist David StJ Astill Damian J Hussey | 2017 | World Journal of Gastroenterology2017，23，30： | 3 |
| 4 | Workspace zonedifferentiation tool for visualization of seated postural com-fort显示文摘 | Yang J Z Uday V Timothy M | 2009 | International Journal of Industrial Ergonomics2009，，39： | 1 |
| 5 | Autoinduction of the trefoil factor 2 (TFF2) promoter requires an upstream cis -acting element显示文摘 | Clemens J Bulitta John V Fleming Raktima Raychowdhury Douglas Taupin Ian Rosenberg Timothy C Wang | 2002 | Biochemical and Biophysical Research Communications2002，，1： | 1 |
| 6 | Effect of organic amendments and slow-release nitrogen fertilizer on willow biomass production and soil chemical characteristics 显示文摘 | Hector G A Russell D B Timothy A V | 2003 | Biomass Bioenerg2003，25，： | 1 |
| 7 | Mechanisms underlying nonsteroidal anti-inflammatory drugmediated apoptosis显示文摘 | Timothy AC Patrice JM Bert V | 1998 | Proc Natl Acad Sci USA1998，95，7： | 1 |
| 8 | Femtosecond laser cataract surgery: technology and clinical practice显示文摘 | Timothy V Roberts Michael Lawless Colin CK Chan Mark Jacobs David Ng Shveta J Bali Chris Hodge Gerard Sutton | 2012 | Clinical & Experimental Ophthalmology2012，，2： | 1 |
| 9 | Impact of microwave blanching on the flavor of roasted peanuts 显示文摘 | Aanriana V S Maryanne D Timothy H S | 2006 | J Sensory Studies2006，21，4： | 1 |
| 10 | Diesel Emission Control in Review 显示文摘 | Timothy V J | 2009 | SAE Paper2009，，： | 1 |
| 11 | Low-Density lipoprotein apheresis for the treatment of refractory hyperlipidemia显示文摘 | Adrian V Alvaro AP Timothy OB | 2001 | Mayo Clin Proc2001，76，： | 1 |
| 12 | Mercury toxicity tue to use of a cosmetic cream 显示文摘 | Cheryl M Leslie V B Timothy J F | 2000 | Occup Environ Med2000，42，1： | 1 |
| 13 | Continuing bone expansion and increasing bone loss over a two-decade period in men and women from a total community sample显示文摘 | Sullivan Timothy V Decker sauy | 1992 | American Journal of Human Biology1992，，4： | 1 |
| 14 | Foodborne Campylobacter: Infections, Metabolism, Pathogenesis and Reservoirs显示文摘 | Epps Sharon V R Harvey Roger B Hume Michael E Phillips Timothy D Anderson Robin C Nisbet David J | 2013 | International Journal of Environmental Research and Public Health2013，，12： | 1 |
| 15 | Mercury toxicity due to use of a cosmetic cream 显示文摘 | Cheryl M Leslie V B Timothy J F | 2000 | J Occup Environ Med2000，42，1： | 1 |
| 16 | Neuromuscular Training Techniques to Target Deficits Before Return to Sport After Anterior Cruciate Ligament Reconstruction显示文摘 | Gregory D Myer Mark V Paterno Kevin R Ford Timothy E Hewett | 2008 | Journal of Strength and Conditioning Research2008，，3： | 1 |
| 17 | Efficacy of difloxacin in calves experimentally infected with Mannheimia haemolytica显示文摘 | Timothy W J Olchowy D V M phD | 2000 | American Journal of Veterinary Research2000，61，6： | 1 |
| 18 | Early psychological adjustment in breast cancer patients-A prospective study显示文摘 | Chiara N Jonathan V R Timothy C | 2002 | J Psycho Res2002，53，6： | 1 |
| 19 | Representation of skew in time-stepped two-dimensional finite-element models of electrical machines 显示文摘 | Stephen W Timothy J F Albertus F V | 1995 | IEEE Transactions on Industry Applications1995，31，5： | 1 |
| 20 | Customer Life Time Value Approaches and Best Practiee Applications显示文摘 | V Kumar Gifish Ranlani Timothy Bohling | 2004 | Journal of Interactive Marketing2004，18，3： | 1 |
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