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| 1 | 全海水灌溉的作物——北美海蓬子(下)显示文摘 | 吕忠进 Edward P. Glenn Roy M. Hodges Carl Hodges | 2001 | 世界农业2001，，3： | 20 |
| 2 | 射血分数正常心力衰竭的患病率和临床结局的变化趋势显示文摘Background: The prevalence of heart failure with preserved ejection fraction may be changing as a result of changes in population demographics and in the prevalence and treatment of risk factors for heart failure. Changes in the prevalence of heart failure with preserved ejection fraction may contribute to changes in the natural history of heart failure. We performed a study to define secular trends in the prevalence of heart failure with preserved ejection fraction among patients at a single institution over a 15-year period. Methods: We studied all consecutive patients hospitalized with decompensated heart failure at Mayo Clinic Hospitals in Olmsted County, Minnesota, from 1987 through 2001. We classified patients as having either preserved or reduced ejection fraction. The patients were also classified as community patients(Olmsted County residents) or referral patients. Secular trends in the type of heart failure, associated cardiovascular disease, and survival were defined. Results: A total of 6076 patients with heart failure were discharged over the 15-year period; data on ejection fraction were available for 4596 of these patients(76 percent). Of these, 53 percent had a reduced ejection fraction and 47 percent had a preserved ejection fraction. The proportion of patients with the diagnosis of heart failure with preserved ejection fraction increased over time and was significantly higher among community patients than among referral patients(55 percent vs. 45 percent). The prevalence rates of hypertension, atrial fibrillation, and diabetes among patients with heart failure increased significantly over time. Survival was slightly better among patients with preserved ejection fraction(adjusted hazard ratio for death, 0.96; P=0.01). Survival improved over time for those with reduced ejection fraction but not for those with preserved ejection fraction. Conclusions: The prevalence of heart failure with preserved ejection fraction increased over a 15-year period, while the rate of death from this disorder remained unchanged. These trends underscore the importance of this growing public health problem. | Owan T.E. Hodge D.O. Herges R.M. M.M. Redfield 马超 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，，12： | 11 |
| 3 | 躯干运动和负重时对足底支撑面侧向横移的姿势控制显示文摘目的 :本研究假设自主运动命令和姿势控制信号间有冲突 ,因此设计在附加重物和不同自主任务的同时给予足底一个模拟受滑的干扰 (横移 )来观察姿势变化并分析其是否受冲突命令或者力学参数的影响。方法 :受试者在执行各种不同的自主任务时 ,随机给予足底支撑面一个左侧或右侧的横移干扰。这些不同的自主任务包括不负重静止站立、静止站立单手负重 5kg、负重 5kg站立并躯干静止侧屈 15°、负重 5kg动态地提重物和放重物 5项任务。测量和分析下列参数 :中心压力的侧位移(COP)、躯干和股部在冠状面上的角位移和腹内压 (IAP)。结果 :干扰离开质量 (向右 )、始反应超射的幅度、达到终平衡的时间和达到平衡前COP位移的次数都增加 ,这种情况可以看作是为了再获得平衡的姿势反应效率降低 ,因此 ,如果质量的重力效果能对抗干扰 ,则再获得平衡的反应效率甚至可以被增进。结论 :提重和负重是危害姿势反应效率的因素 ,因为提重和负重改变了重力效果 ,加大了对躯干的干扰。在动态条件下躯干的运动不是被横移干扰增强就是被横移干扰抵消 ,并没有显著地影响改变最终平衡位置姿势校正的效应。因此附加任务的同时给一个支持面上的横移干扰 ,姿势控制的效应可以被抵消。 | 黄强民 Panl Hodges Alf Thorstensson | 2004 | 中国运动医学杂志2004，23，2： | 6 |
| 4 | 几种常用诊断痴呆的认知筛查工具显示文摘认知功能的评估应成为对临床怀疑痴呆的患者临床评估的常规组成部分。认知功能的下降是痴呆的一个重要标志,但不是痴呆所特有的症状。一些其他临床情况.如抑郁或谵妄也都可出现认知功能障碍,这些情况会影响对患者存在痴呆的认识。引起痴呆的不同原因会产生不同方面的认知损害,认识到这一点,有助于临床准确诊断。 | Eneida Mioshi John R Hodges 潘小玲 王刚 Yue Huang 陈生弟 | 2009 | 内科理论与实践2009，，4： | 5 |
| 5 | 抗炎介质表达缺陷参与中性粒细胞型支气管哮喘发病机制:半乳糖凝集素-3和白细胞介素-1RA/白细胞介素-1beta比例显著下降显示文摘支气管哮喘(哮喘)是具有异质性的气道炎症性疾病,其主要特点表现为气道高反应和可变的气流受限。在哮喘的发病机制中,过敏原诱导的TH2淋巴细胞激活以及IL-5介导的嗜酸粒细胞渗出起到重要的作用。近年来发现超过50%的哮喘患者气道的嗜酸粒细胞水平并不增高,并将这种亚型定义为非嗜酸粒细胞型哮喘。其中部分患者表现为气道中性粒细胞明显增高,称为中性粒细胞型哮喘。 | 高鹏 Peter G Gibson Katherine J Baines Ian A Yang John W Upham Paul N Reynolds Sandra Hodge Alan L James Christine Jenkins Matthew J Peters 张捷 Jodie L Simpson | 2016 | 中华结核和呼吸杂志2016，39，11： | 5 |
| 6 | 不同转基因番茄GalUR的表达与Vc含量显示文摘为了得到高维生素C(Vc)含量新品种,克隆和构建了GalUR半乳糖醛酸还原酶基因,并转入了番茄.通过不同转基因突变体GalUR基因表达和Vc含量分析发现:GalUR基因在转GalUR基因番茄中得到了过量表达;在转FRO2-铁还原酶基因的番茄突变体中表达量增加了60%;在耐贮藏转基因番茄F3、F2、F1中也均高于对照,其中F3的表达量最高,是对照的2~3倍;在非转基因中蔬4号和6号的表达量高于丽春番茄1倍;所有供试GalUR基因表达量均为红果最多、粉红果次之,青果最少.转基因番茄果实Vc含量变化与上述GalUR基因的表达有相同规律.转GalUR3基因番茄果实和叶片Vc含量高于对照2倍以上.GalUR基因的表达还与乙烯合成酶基因ACS、CTR1和铁还原酶FRO2基因的表达有关. | 张伟玉 杨静慧 Gefu Wang-Pruski Mark Hodge 赵亚萍 梁国鲁 | 2008 | 西南大学学报(自然科学版)2008，30，2： | 5 |
| 7 | 中国头针治疗小儿脑瘫(英文)显示文摘目的:观察头针治疗脑性瘫痪的疗效。方法:笔者在美国对36位脑性瘫痪儿童进行了头针治疗。选穴以足运感区、平衡区为主,根据患者个体情况,配合选择言语Ⅰ区,言语Ⅱ区,视区等,针刺过程中行针捻转后留置头针30分钟。结果:在3到20次治疗后,治愈5例,14例取得了显著疗效,14例有效,3例无效。在治疗过程中无不良反应发生。结论:目前头皮针刺已成为脑瘫治疗的首选方法,通过观察纳入病例,发现头针缓解了脑瘫患儿的肢体痉挛、运动障碍、言语不能、认知障碍等,提高了病人的生活质量,改善了身体残疾症状,部分脑瘫患者可以完全康复。这些脑瘫的病例为美国神经针灸研究院与博瑞西医大学联合研究头针治疗小儿脑瘫的临床应用奠定了良好的基础。 | 吕晓琳 郝吉顺 孙忠人 David Riley 南志忠 Brian McKenna Thomas Hodge | 2017 | World Journal of Acupuncture-Moxibustion2017，27，2： | 5 |
| 8 | Improving the thiobarbituric acid-reactive-substances assay for estimating lipid peroxidation in plant tissues containing anthocyanin and other interfering compounds显示文摘 | D. Mark Hodges John M. DeLong Charles F. Forney Robert K. Prange | 1999 | Planta1999，，4： | 4 |
| 9 | 用聚合酶链反应和地高辛系统检测t(14;18)显示文摘目的探索聚合酶链反应(PCR)和地高辛系统检测 t(14;18)的特异性和敏感性。方法用该法检测了不同来源 DNA 标本中的 t(14;18)。结果 3株阳性对照细胞系、14例滤泡性非何杰金淋巴瘤(FNHL)中13例、4例弥漫性非何杰金淋巴瘤(DNHL)中2例的 DNA 内检出 bcl-2-JH 基因;阴性对照细胞系、正常人和其他肿瘤 DNA 中均未检出 t(14;18)。DNA 序列测定结果亦证实检出的阳性片段确实为 bcl-2-JH 基因。敏感性分析结果证实该法较单用 PCR 技术敏感1000~10000倍。结论 PCR 和地高辛系统确为敏感、特异、实用和对人体无害的检测 t(14;18)的方法。 | 唐恩洁 Hodges E. Smith L.J. | 1996 | 中华医学检验杂志1996，19，1： | 4 |
| 10 | 额颞叶痴呆显示文摘一、前言
额颞叶痴呆(frontotemporal dementia,FFD)是一组临床痴呆症候群,由前额叶和颞叶变性引起,其病理表现与阿尔茨海默病(AD)不同,病理上称之为额颞叶变性(frontotemporal lobe degeneration,FTLD)。以往临床上也称为皮克病(Pick disease)。 | 黄越 Glenda Halliday 陈生弟 John Hodges | 2008 | 中华神经科杂志2008，41，12： | 4 |
| 11 | Monitoring vegetation phenology using MODIS显示文摘 | Xiaoyang Zhang Mark A. Friedl Crystal B. Schaaf Alan H. Strahler John C.F. Hodges Feng Gao Bradley C. Reed Alfredo Huete | 2002 | Remote Sensing of Environment2002，，3： | 4 |
| 12 | 两轮多重反转录巢式PCR方法扩增全长GalUR基因(英文)显示文摘研究了两轮多重反转录巢式PCR扩增全长基因的方法。先用多重巢式引物和cDNA进行第1轮PCR扩增;再用纯化的第1轮PCR产物和相同的引物进行第2轮扩增;最后通过改变Mg2+浓度、退火时间和退火温度进行PCR条件的优化,以增加PCR扩增的产量,用于克隆。结果显示该方法方便和快速地扩增出了草莓(Fragariaananassacv.SweatCharlie)高产量和高质量的全长GalUR基因,也非常快速地扩增出了用于基因构建的带有酶切位点的全长GalUR基因。该方法也可以用于其它全长基因的克隆。 | 杨静慧 Gefu Wang-Pruski Mark Hodges | 2005 | 农业生物技术学报2005，13，6： | 3 |
| 13 | Comparison of a Manual and an Automated Tracking Method for Tibetan Plateau Vortices显示文摘Tibetan Plateau vortices(TPVs) are mesoscale cyclones originating over the Tibetan Plateau(TP) during the extended summer season(April–September).Most TPVs stay on the TP,but a small number can move off the TP to the east.TPVs are known to be one of the main precipitation-bearing systems on the TP and moving-off TPVs have been associated with heavy precipitation and flooding downstream of the TP(e.g.,in Sichuan province or over the Yangtze River Valley).Identifying and tracking TPVs is difficult because of their comparatively small horizontal extent(400–800 km) and the limited availability of soundings over the TP,which in turn constitutes a challenge for short-term predictions of TPV-related impacts and for the climatological study of TPVs.In this study,(i) manual tracking(MT) results using radiosonde data from a network over and downstream of the TP are compared with(ii) results obtained by an automated tracking(AT) algorithm applied to ERA-Interim data.Ten MT-TPV cases are selected based on method(i) and matched to and compared with the corresponding AT-TPVs identified with method(ii).Conversely,ten AT-TPVs are selected and compared with the corresponding MT-TPVs.In general,the comparison shows good results in cases where the underlying data are in good agreement,but considerable differences are also seen in some cases and explained in terms of differences in the tracking methods,data availability/coverage and disagreement between sounding and ERA-Interim data.Recommendations are given for future efforts in TPV detection and tracking,including in an operational weather forecasting context. | Julia CURIO Yongren CHEN Reinhard SCHIEMANN Andrew G. TURNER Kai Chi WONG Kevin HODGES Yueqing LI | 2018 | Advances in Atmospheric Sciences2018，35，8： | 3 |
| 14 | The role of IL-6 and STAT3 in inflammation and cancer显示文摘 | David R. Hodge Elaine M. Hurt William L. Farrar | 2005 | European Journal of Cancer2005，，16： | 3 |
| 15 | Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer's disease显示文摘Background:There is an urgent need to understand the pathways and processes underlying Alzheimer's disease(AD)for early diagnosis and development of effective treatments.This study was aimed to investigate Alzheimer's dementia using an unsupervised lipid,protein and gene multi-omics integrative approach.Methods:A lipidomics dataset comprising 185 AD patients,40 mild cognitive impairment(MCI)individuals and 185 controls,and two proteomics datasets(295 AD,159 MCI and 197 controls)were used for weighted gene CO-expression network analyses(WGCNA).Correlations of modules created within each modality with clinical AD diagnosis,brain atrophy measures and disease progression,as well as their correlations with each other,were analyzed.Gene ontology enrichment analysis was employed to examine the biological processes and molecular and cellular functions of protein modules associated with AD phenotypes.Lipid species were annotated in the lipid modules associated with AD phenotypes.The associations between established AD risk loci and the lipid/protein modules that showed high correlation with AD phenotypes were also explored.Results:Five of the 20 identified lipid modules and five of the 17 identified protein modules were correlated with clinical AD diagnosis,brain atrophy measures and disease progression.The lipid modules comprising phospholipids,triglycerides,sphingolipids and cholesterol esters were correlated with AD risk loci involved in immune response and lipid metabolism.The five protein modules involved in positive regulation of cytokine production,neutrophil-mediated immunity,and humoral immune responses were correlated with AD risk loci involved in immune and complement systems and in lipid metabolism(the APOE ε4 genotype).Conclusions:Modules of tightly regulated lipids and proteins,drivers in lipid homeostasis and innate immunity,are strongly associated with AD phenotypes. | Jin Xu Giulia Bankov Min Kim Asger Wretlind Jodie Lord Rebecca Green Angela Hodges Abdul Hye Dag Aarsland Latha Velayudhan Richard J.B.Dobson Petroula Proitsi Cristina Legido-Quigley on behalf of the AddNeuroMed Consortium | 2020 | Translational Neurodegeneration2020，9，3： | 3 |
| 16 | Monitoring vegetation phenology using MODIS显示文摘 | Xiaoyang Zhang Mark A. Friedl Crystal B. Schaaf Alan H. Strahler John C.F. Hodges Feng Gao Bradley C. Reed Alfredo Huete | 2002 | Remote Sensing of Environment2002，，3： | 2 |
| 17 | Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis显示文摘 | Vanessa Stadlbauer Rajeshwar P. Mookerjee Stephen Hodges Gavin A.K. Wright Nathan A. Davies Rajiv Jalan | 2008 | Journal of Hepatology2008，，6： | 2 |
| 18 | Expression of the Chemokine Receptors CCR4, CCR5, and CXCR3 by Human Tissue-Infiltrating Lymphocytes显示文摘 | Eric J. Kunkel Judie Boisvert Kristine Murphy Mark A. Vierra Mark C. Genovese Andrew J. Wardlaw Harry B. Greenberg Martin R. Hodge Lijun Wu Eugene C. Butcher James J. Campbell | 2002 | The American Journal of Pathology2002，，1： | 2 |
| 19 | Global land cover mapping from MODIS: algorithms and early results显示文摘 | M.A Friedl D.K McIver J.C.F Hodges X.Y Zhang D Muchoney A.H Strahler C.E Woodcock S Gopal A Schneider A Cooper A Baccini F Gao C Schaaf | 2002 | Remote Sensing of Environment2002，，1： | 2 |
| 20 | Obstructive Sleep Apnea, Obesity, and the Risk of Incident Atrial Fibrillation显示文摘 | Apoor S. Gami Dave O. Hodge Regina M. Herges Eric J. Olson Jiri Nykodym Tomas Kara Virend K. Somers | 2007 | Journal of the American College of Cardiology2007，，5： | 2 |
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