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| 1 | Marginal revenue of land and total factor productivity in Chinese agriculture: Evidence from spatial analysis显示文摘这份报纸试图探索土地,全部的因素生产率(TFP ) 变化和它的三个部件的边缘的收入的时间、空间的性质:技术变化(TC ) ,技术效率变化(侦探) 和规模效率变化(秒) 是从 1995 ~ 1999 在中国农业生产看。基于县级的数据,学习利用了随机的边疆和印射的分析方法。在最获得发生在东方沿海的地区的地方,结果证明在土地的边缘的收入的生长越过各种各样的区域是多样的,当损失在西北和诺思中国时。中国与可观的地区性的变化在年度 TFP 变化(0.26%) 经历了中等减少。明确地,在谷物生产的行政干预和农业技术散开系统的恶化在年度 TFP 变化导致了中等落下。县级的印射分析在 TFP 和它的部件考虑了 interregional 变化。关于 TFP 的部件,侦探差别在 TFP 解释地区性的分散的多数。作为在中国的发达区域, Huang-Huai-Hai 区域和 Beijing-Tianjin-Tangshan 经济地区在都市化的过程中面对陆地变换和谷物安全的挑战。 | HOU Linke ZHANG Yanjie ZHAN Jinyan Thomas GLAUBEN | 2012 | Journal of Geographical Sciences2012，22，1： | 12 |
| 2 | Helicobacter pylori vac A genotype is a predominant determinant of immune response to Helicobacter pylori CagA显示文摘AIM To evaluate the frequency of Helicobacter pylori(H. pylori) Cag A antibodies in H. pylori infected subjects and to identify potential histopathological and bacterial factors related to H. pylori Cag A-immune response.METHODS Systematic data to H. pylori isolates, blood samples, gastric biopsies for histological and molecular analyses were available from 99 prospectively recruited subjects. Serological profile(anti-H. pylori, anti-Cag A) was correlated with H. pylori isolates(cag A, EPIYA, vac A s/m genotype), histology(Sydney classification) and mucosal interleukin-8(IL-8) m RNA and protein expression. Selected H. pylori strains were assessed for H. pylori Cag A protein expression and IL-8 induction in co-cultivation model with AGS cells.RESULTS Thirty point three percent of microbiologically confirmed H. pylori infected patients were seropositive for Cag A. Majority of H. pylori isolates were cag A gene positive(93.9%) with following vac A polymorphisms: 42.4% vac A s1m1, 23.2% s1m2 and 34.3% s2m2. Anti-Cag AIg G seropositivity was strongly associated with atrophic gastritis, increased mucosal inflammation according to the Sydney score, IL-8 and cag A m RNA expression. V a c A s a n d m p o l y m o r p h i s m s w e r e t h e m a j o r determinants for positive(vac A s1m1) or negative(vac A s2m2) anti-Cag A serological immune response, which also correlated with the in vitro inflammatory potential in AGS cells. In vitro co-cultivation of representative H. pylori strains with AGS cells confirmed functional Cag A translocation, which showed only partial correlation with Cag A seropositivity in patients, supporting vac A as major co-determinant of the immune response.CONCLUSION Serological immune response to H. pylori cag A + strain in H. pylori infected patients is strongly associated with vac A polymorphism, suggesting the crucial role of bacterial factors in immune and clinical phenotype of the infection. | Alexander Link Cosima Langner Wiebke Schirrmeister Wiebke Habendorf Jochen Weigt Marino Venerito Ina Tammer Dirk Schlüter Philipp Schlaermann Thomas F Meyer Thomas Wex Peter Malfertheiner | 2017 | World Journal of Gastroenterology2017，23，26： | 12 |
| 3 | LONG-TERM SURVIVAL ANALYSIS AFTER LAPAROSCOPIC RADICAL NEPHRECTOMY显示文摘 | SOMPOL PERMPONGKOSOL DAVID Y. CHAN RICHARD E. LINK MYRNA SROKA MOHAMAD ALLAF IOANNIS VARKARAKIS GUILHERME LIMA THOMAS W. JARRETT LOUIS R. KAVOUSSI | 2005 | The Journal of Urology2005，，4： | 2 |
| 4 | Polymorphisms of micro RNA target genes IL12B, INSR, CCND1 and IL10 in gastric cancer显示文摘AIM To evaluate associations between mi RNA target genes IL12B,INSR,CCND1 and IL10 polymorphisms and gastric cancer(GC)in European population.METHODS Gene polymorphisms were analyzed in 508 controls and474 GC patients from 3 tertiary centers in Germany,Lithuania and Latvia.Controls were patients from the out-patient departments,who were referred for upper endoscopy because of dyspeptic symptoms and had no history of previous malignancy.Gastric cancer(GC)patients had histopathological verification of gastric adenocarcinoma.Genomic DNA was extracted using salting out method from peripheral blood mononuclear cells.IL12B T>G(rs1368439),INSR T>C(rs1051690),CCND1 A>C(rs7177)and IL10 T>C(rs3024498)SNPs were genotyped by the real-time polymerase chain reaction.Associations between gene polymorphism and GC were evaluated using multiple logistic regression analysis with adjustment for sex,age and country of birth.RESULTS We observed similar distribution of genotypes and allelic frequencies of all polymorphisms between GC patients and controls except of INSR rs1051690.The frequency of the T allele of INSR gene was significantly higher in GC patients than in controls(23.26%and 19.19%respectively,P=0.028).CT genotype was also more prevalent in patients compared to control group(38.48%and 30.12%respectively,P<0.021).Logistic regression analysis revealed that only one polymorphism(rs1051690 in INSR gene)was associated with increased risk of GC.Carriers of CT genotype had higher odds of GC when compared to CC genotype(OR=1.45,95%PI:1.08-1.95,P=0.01).Similar association was observed in a dominant model for INSR gene,where comparison of TT+CT vs CC genotypes showed an increased risk of GC(OR=1.44,95%PI:1.08-1.90,P=0.01).Other analyzed SNPs were not associated with the presence of GC.CONCLUSION INSR rs1051690 SNP is associated with increased risk of GC,while polymorphisms in IL12B,CCND1 and IL10genes are not linked with the presence of GC. | Vytenis Petkevicius Violeta Salteniene Simonas Juzenas Thomas Wex Alexander Link Marcis Leja Ruta Steponaitiene Jurgita Skieceviciene Limas Kupcinskas Laimas Jonaitis Gediminas Kiudelis Peter Malfertheiner Juozas Kupcinskas | 2017 | World Journal of Gastroenterology2017，23，19： | 2 |
| 5 | Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor显示文摘 | Thomas J Liu F Link DC | 2002 | Curr Opinion Hematol2002，9，3： | 1 |
| 6 | Iron-oxide-enhanced MR imaging of bone marrow in patients with non-Hodgkin’s lymphoma: differentiation between tumor infiltration and hypercellular bone marrow显示文摘 | Heike E. Daldrup-Link Ernst J. Rummeny Bettina Ihssen Joachim Kienast Thomas M. Link | 2001 | European Radiology2001，，： | 1 |
| 7 | Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor显示文摘 | Thomas J Liu F Link DC | 2002 | Curt Opin Hematol2002，9，3： | 1 |
| 8 | Computation of a Nonequilibrium Expansion Flow in a Single Expansion Ramp Nozzle 显示文摘 | Thomas Link Wolfgang W K | 2001 | Journal of Propulsion and Power2001，17，6： | 1 |
| 9 | Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor显示文摘 | Thomas J Liu F Link DC | 2002 | Curr Opinion Hematol2002，9，3： | 1 |
| 10 | Cartilage imaging: motivation, techniques, current and future significance显示文摘 | Thomas M. Link Robert Stahl Klaus Woertler | 2007 | European Radiology2007，，5： | 1 |
| 11 | Actions of the antiarrhythmic peptide AAP10 on intercellular coupling显示文摘 | A. Müller Thomas Schaefer Werner Linke Tatjana Tudyka Michaela Gottwald Wolfgang Klaus Stefan Dhein | 1997 | Naunyn - Schmiedeberg’s Archives of Pharmacology1997，，1： | 1 |
| 12 | Complications of 2,775 Urological Laparoscopic Procedures: 1993 to 2005显示文摘 | Sompol Permpongkosol Richard E. Link Li-Ming Su Frederico R. Romero Herman S. Bagga Christian P. Pavlovich Thomas W. Jarrett Louis R. Kavoussi | 2007 | The Journal of Urology2007，，2： | 1 |
| 13 | Mitochondrial effects on flower and pollen development显示文摘 | BA LINKE THOMAS BORNER | 2005 | Mitochondrion2005，5，： | 1 |
| 14 | MRI‐guided high‐intensity focused ultrasound ablation of bone: Evaluation of acute findings with MR and CT imaging in a swine model显示文摘 | Matthew D. Bucknor Viola Rieke Loi Do Sharmila Majumdar Thomas M. Link Maythem Saeed | 2014 | J. Magn. Reson. Imaging2014，，： | 1 |
| 15 | The influence of disuse on bone microstructure and mechanics assessed by HR-pQCT显示文摘 | Galateia J Kazakia Willy Tjong Jasmine A Nirody Andrew J Burghardt Julio Carballido-Gamio Janina M Patsch Thomas Link Brian T Feeley C Benjamin Ma | 2014 | Bone2014，63，： | 1 |
| 16 | FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings显示文摘 | Alexander Stahl Katja Ott Wolfgang Weber Karen Becker Thomas Link J?rg-Rüdiger Siewert Markus Schwaiger Ulrich Fink | 2003 | European Journal of Nuclear Medicine and Molecular Imaging2003，，2： | 1 |
| 17 | FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings显示文摘 | Alexander Stahl Katja Ott Wolfgang Weber Karen Becker Thomas Link J?rg-Rüdiger Siewert Markus Schwaiger Ulrich Fink | 2003 | European Journal of Nuclear Medicine and Molecular Imaging2003，，2： | 1 |
| 18 | Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor显示文摘 | Thomas J Liu F Link D C | 2002 | Curr Opin Hematol2002，9，3： | 1 |
| 19 | Prophylactic Implantable Defibrillator in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia and No Prior Ventricular Fibrillation or Sustained Ventricular Tachycardia显示文摘 | Domenico Corrado Hugh Calkins Mark S. Link Loira Leoni Stefano Favale Michela Bevilacqua Cristina Basso Deirdre Ward Giuseppe Boriani Renato Ricci Jonathan P. Piccini Darshan Dalal Massimo Santini Gianfranco Buja Sabino Iliceto N.A. Mark Estes Thomas Wich | 2010 | Circulation2010，，12： | 1 |
| 20 | Efficient Systemic and Mucosal Responses Against the HIV-1 Tat Protein by Prime/boost Vaccination Using the Lipopeptide MALP-2 as Adjuvant显示文摘 | Stefan Borsutzky Thomas Ebensen Claudia Link | 2006 | Vaccine2006，24，12： | 1 |
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