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| 1 | Extracorporeal shock wave lithotripsy for pancreatic and large common bile duct stones显示文摘Extraction of large pancreatic and common bile duct(CBD)calculi has always challenged the therapeutic endoscopist.Extracorporeal shockwave lithotripsy(ESWL)is an excellent tool for patients with large pancreatic and CBD calculi that are not amenable to routine endotherapy.Pancreatic calculi in the head and body are targeted by ESWL,with an aim to fragment them to<3 mm diameter so that they can be extracted by subsequent endoscopic retrograde cholangio-pancreatography(ERCP).In our experience,complete clearance of the pancreatic duct was achieved in 76% and partial clearance in 17%of 1006 patients.Short-term pain relief with reduction in the number of analgesics ingested was seen in 84%of these patients.For large CBD calculi,a nasobiliary tube is placed to help target the calculi,as well as bathe the calculi in salinea simple maneuver which helps to facilitate fragmenta-tion.The aim is to fragment calculi to<5 mm size and clear the same during ERCP.Complete clearance of the CBD was achieved in 84.4%of and partial clearance in 12.3%of 283 patients.More than 90%of the patients with pancreatic and biliary calculi needed three or fewer sessions of ESWL with 5000 shocks being de-livered at each session.The use of epidural anesthesia helped in reducing patient movement.This,together with the better focus achieved with newer third-gen-eration lithotripters,prevents collateral tissue damage and minimizes the complications.Complications in our experience with nearly 1300 patients were minimal,and no extension of hospital stay was required.Similar rates of clearance of pancreatic and biliary calculi with minimal adverse effects have been reported from the centers where ESWL is performed regularly.In view of its high efficiency,non-invasive nature and low complication rates,ESWL can be offered as the first-line therapy for selected patients with large pancreatic and CBD calculi. | Manu Tandan D Nageshwar Reddy | 2011 | World Journal of Gastroenterology2011，17，39： | 36 |
| 2 | Epidural anesthesia is effective for extracorporeal shock wave lithotripsy of pancreatic and biliary calculi显示文摘AIM: To evaluate the efficacy of thoracic epidural analgesia for extracorporeal shock wave lithotripsy (ESWL). METHODS: ESWL is an effective, non-invasive technique for the treatment of difficult pancreatic and large bile duct calculi. The procedure is often painful and requires large doses of analgesics. Many different anesthetic techniques have been used. Patients with either large bile duct calculi or pancreatic duct calculi which could not be extracted by routine endoscopic methods were selected. Thoracic epidural anesthesia (TEA) was routinely used in all the subjects unless contraindicated. Bupivacaine 0.25% with or without clonidine was used to block the segments D6 to D12. The dose was calculated depending on the age, height and weight of the patient. It was usually 1-2 mL per segment blocked.RESULTS: Ninety eight percent of the 1509 patients underwent ESWL under TEA. The subjects selected were within American Society of Anesthesiologists grade Ⅰ to Ⅲ. ESWL using EA permitted successful elimination of bile duct or pancreatic calculi with minimal morbidity. The procedure time was shorter in patients with TEA than in those who underwent ESWL under total intravenous anesthesia. CONCLUSION: Almost all patients undergoing ESWL with EA had effective blocks with a single catheter insertion and local anesthetic injection. | Santosh Darisetty Manu Tandan Duvvuru Nageshwar Reddy Rama Kotla Rajesh Gupta Mohan Ramchandani Sandeep Lakhtakia Guduru Venkat Rao Rupa Banerjee | 2010 | World Journal of Gastrointestinal Surgery2010，2，5： | 13 |
| 3 | Efficacy of low dose peginterferon alpha-2b with ribavirin on chronic hepatitis C显示文摘AIM: To assess the effi cacy of peginterferon alpha 2b at doses of 50 μg weekly and 80 μg weekly (based on body weight) plus ribavirin in HCV genotype 2 and genotype 3 chronic hepatitis C patients. METHODS: During the study period of Jan 2002 to Dec 2003, all patients diagnosed as chronic hepatitis C or HCV related compensated cirrhosis were treated with peginterferon alpha 2b 50 μg S/C weekly (body weight < 60 kg) or 80 μg S/C weekly (body weight > 60 kg) plus ribavirin 800 mg/d for 24 wk. RESULTS: Overall 28 patients, 14 patients in each group (based on body weight) were treated during the period. Out of 28 patients, 75% were genotype 3, 18% were genotype 2 and 7% were genotype 1. The mean dose of peginterferon alpha 2b was 0.91 μg/kg in group 1 and 1.23 μg/kg in group 2 respectively. The end of treatment and sustained virologic response rates were 82% and 78% respectively. Serious adverse effects were seen in 3.5% patients. CONCLUSION: Low dose peginterferon alpha 2b in combination with ribavirin for 24 wk is effective in HCV genotype 2 and 3 chronic hepatitis C patients. | Rajesh Gupta CH Ramakrishna Sandeep Lakhtakia Manu Tandan Rupa Banerjee D Nageshwar Reddy | 2006 | World Journal of Gastroenterology2006，12，34： | 10 |
| 4 | Per oral cholangiopancreatoscopy in pancreatico biliary diseases- Expert consensus statements显示文摘AIM: To provide consensus statements on the use of per-oral cholangiopancreatoscopy(POCPS).METHODS: A workgroup of experts in endoscopic retrograde cholangiopancreatography(ERCP), endosonography, and POCPS generated consensus statements summarizing the utility of POCPS in pancreaticobiliary disease. Recommendation grades used validated evidence ratings of publications from an extensive literature review.RESULTS: Six consensus statements were generated:(1) POCPS is now an important additional tool during ERCP;(2) in patients with indeterminate biliary strictures, POCS and POCS-guided targeted biopsy are useful for establishing a definitive diagnosis;(3) POCS and POCS-guided lithotripsy are recommended for treatment of difficult common bile duct stones when standard techniques fail;(4) in patients with main duct intraductal papillary mucinous neoplasms(IPMN) POPS may be used to assess extent of tumor to assist surgicalresection;(5) in difficult pancreatic ductal stones,POPS-guided lithotripsy may be useful in fragmentation and extraction of stones; and(6) additional indications for POCPS include selective guidewire placement,unexplained hemobilia, assessing intraductal biliary ablation therapy, and extracting migrated stents. CONCLUSION: POCPS is important in association with ERCP, particularly for diagnosis of indeterminate biliary strictures and for intra-ductal lithotripsy when other techniques failed, and may be useful for preoperative assessment of extent of main duct IPMN, for extraction of difficult pancreatic stones, and for unusua indications involving selective guidewire placement,assessing unexplained hemobilia or intraductal biliary ablation therapy, and extracting migrated stents. | Mohan Ramchandani Duvvur Nageshwar Reddy Sundeep Lakhtakia Manu Tandan Amit Maydeo Thoguluva Seshadri Chandrashekhar Ajay Kumar Randhir Sud Rungsun Rerknimitr Dadang Makmun Christopher Khor | 2015 | World Journal of Gastroenterology2015，21，15： | 8 |
| 5 | 欧洲胃肠内镜学会和美国胃肠内镜学会指南预测胆囊切除术患者可疑胆总管结石的临床效果显示文摘【据《Endoscopy》2020年2月在线报道】题:欧洲胃肠内镜学会和美国胃肠内镜学会指南预测胆囊切除术患者可疑胆总管结石的临床效果(作者Jagtap N等)最新版欧洲胃肠内镜学会(ESGE)和美国胃肠内镜学会(ASGE)指南推荐要根据肝功能和腹部超声检查对可疑胆总管结石患者进行风险分层。来自印度海得拉巴亚洲胃肠病研究所的Jagtap等进行了一项研究,评估和验证了ESGE和ASGE新的风险分层标准预测胆总管结石的临床效用。 | 李家速 刘枫 JAGTAP N YASHAVANTH HS TANDAN M | 2020 | 临床肝胆病杂志2020，36，5： | 3 |
| 6 | Factors that impact symptomatic diabetic peripheral neu- ropathy in placebo-administered patients from two 1 -year clinical trials 显示文摘 | Tesfaye S Tandan R Bastyr E J | 2007 | Diabetes Care2007，30，10： | 1 |
| 7 | Laparoscopic pancreatic surgery 显示文摘 | Park A Schwartz R Tandan V | 1999 | Am J Surg1999，17，7： | 1 |
| 8 | Narrow Band Imaging (NBI) Can Detect Minimal Changes in Non Erosive Reflux Disease (NERD) Which Resolve with PPI Therapy显示文摘 | Rupa Banerjee Nitesh Pratap Mohan Ramchandani Manu Tandan Guduru V. Rao D.N. Reddy | 2009 | Gastrointestinal Endoscopy2009，，5： | 1 |
| 9 | Nitric oxide and its modulators inchronic constriction injury-induced neuropathic pain in rats显示文摘 | Naik AK Tandan SK Kumar D | 2006 | Eur JPharmacol2006，530，12： | 1 |
| 10 | Multiple main pancreatic duct stones in tropical panereatitis:safe ctearance with extracorporeal shockwave l ithotripsy显示文摘 | On8 WO Tandan M Peddy V et aI | 2006 | Gastroenteml Hepatot2006，21，10： | 1 |
| 11 | Increased hyperalgesia by5-nitro-2,3-(phenylpropylamino)-benzoic acid(NPPB),a chlo-ride channel blocker in crush injury-induced neuropathic pain inrats显示文摘 | Ramteke V Tandan S Kumar D | 2009 | Pharmacol Biochem Behav2009，9，： | 1 |
| 12 | Influence of simultaneous inhibition of cyclooxygenase- 2 and inducible nitric oxide synthase in experimental colitis in rats 显示文摘 | Dudhgaonkar SP Tandan SK Kumar D | 2007 | Inflammopharmacology2007，15，5： | 1 |
| 13 | Safety and efficacy of ERCP in pregnancy显示文摘 | Gupta R Tandan M Lakhtakia S | 2004 | Gastrointest Endosc2004，60，2： | 1 |
| 14 | Metastasizing thymoma and myasthenia gravis显示文摘 | Tandan R Taylor R Dicostanzo DP | 1990 | Cancer1990，65，： | 1 |
| 15 | Comparative evaluation of fracture resistance of various post systems using different luting agents under tangential loading显示文摘 | Aggarwal R Gupta S Tandan A | 2013 | Journal of Oral Biology and Craniofacial Research2013，3，2： | 1 |
| 16 | Early-onset benign autosomal dominant limb-girdle myopathy with contractures ( Bethlem myopathy) 显示文摘 | Mohire MD Tandan R Fries TJ | 1988 | Neurology1988，38，4： | 1 |
| 17 | Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats显示文摘 | Naik AK Tandan SK Kumar D | 2006 | Eur J Pharmacol2006，530，12： | 1 |
| 18 | A?meliorative effect of combined administration of inducible nitric ox?ide synthase inhibitor with cyclooxygenase-2 inhibitors in neuro?pathic pain in rats显示文摘 | DUDHGAONKAR S p TANDAN S K KUMAR D er al | 2007 | EurJ Pain2007，11，5： | 1 |
| 19 | Extracorporeal shock wave lithotripsy and endotherapy for pancreatic calculi-a large single center experience显示文摘 | Tandan M Reddy DN Santosh D | 2010 | Indian J Gastroenterol2010，29，4： | 1 |
| 20 | Long-term clinical outcomes of extracorporeal shockwave lithotripsy in painful chronic calcific pancreatitis显示文摘 | Tandan M Reddy DN Talukdar R | | 0，，05： | 1 |
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