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| 1 | Reduced antioxidant level and increased oxidative damage in intact liver lobes during ischaemia-reperfusion显示文摘瞄准:为了决定是否增加了,并且详细描述对在老鼠模型上在肝的外科期间测量抗氧化剂防卫合适的方法,肝的血流能引起氧化应力和 hepatocyte 损坏。方法:在戊巴比妥钠昏迷状态,侧面的左和肝的中间的脑叶被抓紧让 45 min 让全部的血供给通过另外的脑叶流动。全部的抗氧化剂地位,谷胱甘肽过氧化物酶和超级氧化物 dysmutase 活动,以及 diene 的集中结合,免费 sulphydril 组织,捐赠 H 能力和肝样品的减少的力量被决定。肝的 Chemiluminescent 紧张也被测量。金属离子(艾尔, Ca, Cu, Fe, Mg, Mn, Zn ) 并且肝的 P 和 S 集中与诱导地联合的血浆被决定光排放分光计和 Se 内容被阴极的的脱衣的 voltammetry 测量。结果:谷胱甘肽过氧化物酶和肝的超级氧化物 dysmutase 活动与在假冒的操作的组观察的那些相比在充血组显著地减少了。全部的抗氧化剂地位的水平在充血组也是显著地更低的。捐赠 H 能力,减少的力量和免费 sulphydril 组集中显示出一样的趋势。重要关联(P<0.05 ) 在非特定的抗氧化剂活动在变化之间被发现。这指向了抗氧化剂防卫系统的同时的活动。当 Ca, Fe, Mg, Se 和 P 离子的层次在充血期间是更高的时,艾尔, Cu, Mn, Zn,和 S 比在假冒的操作的组在充血组是更低的。结论:氧化应力在 ischaemia-reperfusion 期间是为未经触动的肝脑叶的损害的主要因素之一。 | LászlóVáli Gabriella Taba KláraSzentmihályi HedvigFébel TímeaKurucz Zsolt Pallai PéterKupcsulik AnnaBlázovics | 2006 | World Journal of Gastroenterology2006，12，7： | 6 |
| 2 | Expression of Angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumor, leiomyoma and schwannoma显示文摘AIM: To investigate the role of angiopoietin (Ang) -1, -2 and -4 and its receptors, Tie-1 and -2, in the growth and differentiation of gastrointestinal stromal tumors (GISTs).METHODS: Thirty GISTs, seventeen leiomyomas and six schwannomas were examined by immunohistochemistry in this study.RESULTS: Ang-1, -2 and -4 proteins were expressed in the cytoplasm of tumor cells, and Tie-1 and -2 were expressed both in the cytoplasm and on the membrane of all tumors. Immunohistochemical staining revealed that 66.7% of GISTs (20 of 30), 76.5% of leiomyomas (13 of 17) and 83.3% of schwannomas (5 of 6) were positive for Ang-1. 83.3% of GISTs (25 of 30), 82.4% of leiomyomas (14 of 17) and 100% of schwannomas (6 of 6) were positive for Ang-2. 36.7% of GISTs (11 of 30), 58.8% of leiomyomas (10 of 17) and 83.3% of schwannomas (5 of 6) were positive for Ang-4. 60.0% of GISTs (18 of 30), 82.4% of leiomyomas and 100% of schwannomas (6 of 6) were positive for Tie-1. 10.0% of GISTs (3 of 30), 94.1% of leiomyomas (16 of 17) and 33.3% of schwannomas (2 of 6) were positive for Tie-2. Tie-2 expression was statistically different between GISTs and leiomyomas (P < 0.001). However, there was no correlation between expression of angiopoietin pathway components and clinical risk categories.CONCLUSION: Our results suggest that the angiopoietin pathway plays an important role in the differentiation of GISTs, leiomyomas and schwannomas. | Toshiyuki Nakayama Maki Inaba Shinji Naito Yumi Mihara Shiro Miura Mitsuru Taba Ayumi Yoshizaki Chun-Yang Wen Ichiro Sekine | 2007 | World Journal of Gastroenterology2007，13，33： | 6 |
| 3 | Macrophages in the Pathogenesis of Atherosclerosis显示文摘 | Kathryn J. Moore Ira Tabas | 2011 | Cell2011，，3： | 3 |
| 4 | Antimicrobial Agents from Selected Medicinal Plants in Libya显示文摘Objective:To test the in vitro antimicrobial efficacy of water and methanol extracts of 23 plan species that are commonly used in Libyan folk medicine.Methods:The antimicrobial activity was determinec using the well-diffusion method.Four test microorganisms were used namely,Escherichia coli,Salmonella species,Staphylococcus aureus and Bacillus subtilis.The minimum inhibitory concentration(MIC) was determined for the high biologically active crude plant extracts.Results:Among 23 medicinal plants used in the study,only 5 methanolic extracts[Rosmarinus offcinalis L,Carduus marianium L.,Lantana camara L.,Rhus tripartite(ueria) Grande,and Thymus capitatus(L.) Hoffm(link)]showed the highest antimicrobial activity againsl Staphylococcus aureus,Bacillus subtilis and Salmonella species,while 22 methanolic and aqueous extracts showed moderate to weak antimicrobial activity on all tested organisms.However 19 of the extracts showed no activity at all against Gram-ve and Gram +ve microorganisms.MIC was found to be 1.25 mg/mL(Thymus capitatus),3 mg/mL(Rhus tripartite),4 mg/mL(Carduus marianium),5 mg/mL(Rosamarinus officinalis) and5 mg/mL(Lantana camara),respectively.Conclnsions:The present results revealed that,crude methanolic extracts of the investigated Libyan folk medicinal plants exhibited mild to high in vitro antibacterial activities against Gram-positive and Gram-negative microorganisms. | Hasan MH Muhaisen Miftah Mailoud Ab-Mous Fadel A Ddeeb Aboclaid All Rtemi Omer M Taba Mehtab Parveen | 2016 | Chinese Journal of Integrative Medicine2016，22，3： | 2 |
| 5 | Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis显示文摘 | Christopher M. Scull Ira Tabas | 2011 | Arteriosclerosis Thrombosis and Vascular Biology2011，，12： | 2 |
| 6 | Mechanisms of ER stress-induced apoptosis in atherosclerosis 显示文摘 | Scull C M Tabas I | 2011 | Arterioscler Thromb Vasc Biol2011，31，12： | 1 |
| 7 | The response-to-retention hypothesis of early atherogenesis显示文摘 | Williams K J Tabas I | 1995 | Arterioscler Thromb Vasc Biol1995，15，5： | 1 |
| 8 | The role of endoplasmic reticulum stress in the progression of atherosclerosis显示文摘 | TABAS I | 2010 | Circ Res2010，107，7： | 1 |
| 9 | Consequences and therapeutic implications of macro- phage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency显示文摘 | Tabas I | 2005 | Arterioseler Thromb Vasc Bio12005，25，11： | 1 |
| 10 | The response-to-retention hypothesis of atherogenesis reinforced显示文摘 | Williams KJ Tabas I | 1998 | Curr Opin Lipidol1998，9，5： | 1 |
| 11 | Integrating the mechanisms of apoptosis in- duced by endoplasmic reticulum stress 显示文摘 | Tabas I Ron D | 2011 | Nat Cell Biol2011，13，3： | 1 |
| 12 | Inflammation and its Resolution as Determinants of Acute Coronary Syndromes显示文摘 | Peter Libby Ira Tabas Gabrielle Fredman Edward A. Fisher | 2014 | Circulation Research2014，，12： | 1 |
| 13 | Free cholesterol loading of macrophages is as- sociated with wide spread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway显示文摘 | Yao P M Tabas I | 2001 | J Biol Chem2001，276，42： | 1 |
| 14 | Insulin resistance,hyperglycemi-a,and atherosclerosis显示文摘 | Bornfeldt KE Tabas I | 2011 | Cell Metab2011，14，5： | 1 |
| 15 | Subendothelial lipoprotein reten-tion as the initiating process in atherosclerosis : update and thera-peutic implications显示文摘 | Tabas I Williams KJ Bor6n J | 2007 | Circulation2007，116，16： | 1 |
| 16 | Plant genetic resources:What can they contribute toward increased crop productivity显示文摘 | Hoisington D Khairallah M Reeves T Ribaut J.M Skovmand B Taba S and Warburton M | | 0，，： | 1 |
| 17 | Mechanisms of ER stress-induced apoptosis in atherosclerosis显示文摘 | Scull CM Tabas I | 2011 | Arterioscler Thromb Vasc Biol2011，31，12： | 1 |
| 18 | Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis显示文摘 | Xianghai Liao Judith C. Sluimer Ying Wang Manikandan Subramanian Kristy Brown J. Scott Pattison Jeffrey Robbins Jennifer Martinez Ira Tabas | 2012 | Cell Metabolism2012，，4： | 1 |
| 19 | Effects of non-surgical periodontal therapy on glycemic control in patients with type2 diabetes mellitus显示文摘 | Rodrigues DC Taba MJ Novaes AB | 2003 | J Periodontol2003，74，9： | 1 |
| 20 | Fruit rot of Strawberry pear(pitaya) caused by Bipolaris cactivara显示文摘 | Taba S Miyahira N Nasu K | 2007 | J Gen Plant Pathol2007，73，： | 1 |
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