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| 1 | Unusual presentations of eosinophilic gastroenteritis:Case series and review of literature显示文摘Eosinophilic gastroenteritis (EG) is an uncommon disease characterized by focal or diffuse eosinophilic infiltration of the gastrointestinal tract, and is usually associated with dyspepsia, diarrhea and peripheral eosinophilia. Diffuse gastrointestinal tract and colonic involvement are uncommon. The endoscopic appearance may vary from normal to mucosal nodularity and ulceration. Gastrointestinal obstruction is unusual and is associated with predominantly muscular disease. We present five unusual cases of EG associated with gastric outlet and duodenal obstruction. Two cases presented with acute pancreatitis and one had a history of pancreatitis. Four cases responded well to medical therapy and one had recurrent gastric outlet obstruction that required surgery. Four out of the five cases had endoscopic and histological evidence of esophagitis and two had colitis. Two patients had ascites. These cases reaffirm that EG is a disorder with protean manifestations and may involve the entire gastrointestinal tract. Gastric outlet and/or small bowel obstruction is an important though uncommon presentation of EG. It may also present as esophagitis, gastritis with polypoid lesions, ulcers or erosions, colitis and pancreatitis and may mimic malignancy. | Rafiq A Sheikh Thomas P Prindiville R Erick Pecha Boris H Ruebner | 2009 | World Journal of Gastroenterology2009，15，17： | 43 |
| 2 | Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer显示文摘AIM: To assess the proteome of normal versus tumor tissue in squamous cell carcinoma of the esophagus (SCCE) in Iranian patients and compare our results with former reports by using proteomics. METHODS: Protein was extracted from normal and tumor tissues. Two dimensional electrophoresis was carried out and spots with differential expression were identified with mass spectrometry. RNA extraction and RT-PCR along with immunodetection were performed. RESULTS: Fourteen proteins were found whose expression levels differed in tumor compared to normal tissues. Mass spectrometric analysis resulted in the identification of β-tropomyosin (TMβ), myosin light chain 2 (and its isoform), myosin regulatory light chain 2, peroxyredoxin 2, annexinⅠand an unknown polypeptide as the down regulated polypeptides in tumor tissue. Heat shock protein 70 (HSP70), TPM4-ALK fusion oncoprotein 2, myosin light polypeptide 6, keratinⅠ, GH16431p and calreticulin were the up-regulated polypeptides found in tumor tissue. Several of these proteins, such as TMβ,HSP70, annexinⅠ, calreticulin, TPM4-ALK and isoforms of myosins, have been well recognized in tumorigenesis of esophageal or other types of cancers. CONCLUSION: Our study not only supports the involve- ment of some of the formerly reported proteins in SCCE but also introduces additional proteins found to be lost in SCCE, including TMβ. | Ferdous Rastgar Jazii Zahra Najafi Reza Malekzadeh Thomas P Conrads Abed Ali Ziaee Christian Abnet Mansour Yazdznbod Ali Asghar Karkhane Ghasem H Salekdeh | 2006 | World Journal of Gastroenterology2006，12，44： | 14 |
| 3 | Faecalibacterium prausnitzii and human intestinal health显示文摘 | S Miquel R Martín O Rossi LG Bermúdez-Humarán JM Chatel H Sokol M Thomas JM Wells P Langella | 2013 | Current Opinion in Microbiology2013，，： | 3 |
| 4 | Axitinib versus sorafenib as first-line therapy in patients with metastatic renal-cell carcinoma: a randomised open-label phase 3 trial显示文摘 | Thomas E Hutson Vladimir Lesovoy Salman Al-Shukri Viktor P Stus Oleg N Lipatov Angel H Bair Brad Rosbrook Connie Chen Sinil Kim Nicholas J Vogelzang | 2013 | Lancet Oncology2013，，13： | 2 |
| 5 | Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients显示文摘 | G Fattovich G Giustina F Degos F Tremolada G Diodati P Almasio F Nevens A Solinas D Mura JT Brouwer H Thomas C Njapoum C Casarin P Bonetti P Fuschi J Basho A Tocco A Bhalla R Galassini F Noventa SW Schalm G Realdi | 1997 | Gastroenterology1997，，2： | 2 |
| 6 | Hydroxyethyl Starch Reduces Coagulation Competence and Increases Blood Loss During Major Surgery: Results From a Randomized Controlled Trial显示文摘 | Kirsten C. Rasmussen P?r I. Johansson Michael H?jskov Irina Kridina Thomas Kistorp Peter Thind Henning B. Nielsen Birgitte Ruhnau Tom Pedersen Niels H. Secher | 2014 | Annals of Surgery2014，，2： | 2 |
| 7 | The size of flames from natural fires显示文摘 | Thomas P H | 1962 | Fire Research Note1962，，497： | 1 |
| 8 | Three dimensional transonic aeroelasticity using proper orthogonal decompo- sition-based reduced order models显示文摘 | Thomas J P Dowell E H Hall K C | 2003 | Journal of Aircraft2003，40，3： | 1 |
| 9 | Relationships between flow, self-concept, psychological skills, and performance 显示文摘 | JACKSON S A THOMAS P R MARSH H W | 2001 | Journal of Aoolied Soort Psvcholow2001，13，2： | 1 |
| 10 | Gold and trace element zonation in pyrite using a laser imaging technique: Implications for the timing of gold in orogenic and Carlin- style sediment- hosted deposits 显示文摘 | R R Large L Danyushevsky C Hollit V Maslennikov S Meffer S Gilbert S Bull R Scott P Emsbo H Thomas B Singh J Foster | 2009 | Economic Geology2009，104，5： | 1 |
| 11 | Multicell converters: basic concepts and industry applications显示文摘 | MEYNARD T A FOCH H THOMAS P | 2002 | IEEE Trans on Industrial Electronics2002，49，5： | 1 |
| 12 | Opposite clear corneal incisions on the steep meridian in phacoemulsification:early effects on the cornea显示文摘 | Tadros A Habib M Tejwani D von Lany H Thomas P | 2004 | J Cataract Refract Surg2004，30，2： | 1 |
| 13 | Gaussian random number generators显示文摘 | Thomas D B Luk W Leong P H W etal | 2007 | ACM Computing Surveys2007，39，4： | 1 |
| 14 | Chemical anal-ysis of contaminated soil strengthened by the addition of lime显示文摘 | Mckinley J D Thomas H R Williams K P | 2001 | Engineering Geology2001，60，： | 1 |
| 15 | Replicative competence of the T131I, K141E, and G145R surface variants of hepatitis B virus显示文摘 | JAMMEH S THOMAS H C KARAYIANNIS P | 2007 | J I D2007，196，1： | 1 |
| 16 | Movement of smoke in horizontal corridors against an air flow显示文摘 | Thomas P H | 1970 | Institute of Fire Engineers Quarterly1970，30，77： | 1 |
| 17 | Carboxymethyl xylan-control of properties by synthesis 显示文摘 | Thomas H Katrin P Katrin S | 2005 | Macromol Sympo2005，232，1： | 1 |
| 18 | Transonic limit cycle oscillation analysis using reduced order aerodynamic modds显示文摘 | Dowell E H Thomas J P Hall K C | 2004 | Journal of Fluids and Structures2004，，19： | 1 |
| 19 | Identification of polymorphic outer membrane protein of Chlamydia psittaic 6BC 显示文摘 | Regina J T David L Thomas P H | 2001 | Infect and Immun2001，69，： | 1 |
| 20 | Pan Evaporation Trends in Dry Hu- mid Regions of the United States显示文摘 | JAY H L THOMAS C P | 2000 | Journal of Hydrometeo- rology2000，1，6： | 1 |
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