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| 1 | 生物防治作用物风险评价的方法显示文摘本文针对生防作用物安全性常规测定方法的不足之处,提出了引进生防作用物的风险评价理论与方法,以正确评价引入天敌的安全性和可利用性,解决理论及实践上面临的新问题,为决策部门提供可靠的依据。风险评价包括风险分析与风险控制,对生防作用物的为害性识别、风险识别及风险定量研究是风险评价的主要内容。 | 万方浩 叶正楚 Peter Haris | 1997 | 中国生物防治1997，13，1： | 35 |
| 2 | Optimal Control of Nonlinear Inverted Pendulum System Using PID Controller and LQR: Performance Analysis Without and With Disturbance Input显示文摘Linear quadratic regulator(LQR) and proportional-integral-derivative(PID) control methods, which are generally used for control of linear dynamical systems, are used in this paper to control the nonlinear dynamical system. LQR is one of the optimal control techniques, which takes into account the states of the dynamical system and control input to make the optimal control decisions.The nonlinear system states are fed to LQR which is designed using a linear state-space model. This is simple as well as robust. The inverted pendulum, a highly nonlinear unstable system, is used as a benchmark for implementing the control methods. Here the control objective is to control the system such that the cart reaches a desired position and the inverted pendulum stabilizes in the upright position. In this paper, the modeling and simulation for optimal control design of nonlinear inverted pendulum-cart dynamic system using PID controller and LQR have been presented for both cases of without and with disturbance input. The Matlab-Simulink models have been developed for simulation and performance analysis of the control schemes. The simulation results justify the comparative advantage of LQR control method. | Lal Bahadur Prasad Barjeev Tyagi Hari Om Gupta | 2014 | International Journal of Automation and computing2014，11，6： | 32 |
| 3 | Recent advances based on the synergetic effect of adsorption for removal of dyes from waste water using photocatalytic process显示文摘The problem of textile dye pollution has been addressed by various methods,mainly physical,chemical,biological,and acoustical.These methods mainly separate and/or remove the dye present in water.Recently,advanced oxidation processes(AOP)have been focused for removal of dye from waste water due to their advantages such as ecofriendly,economic and capable to degrade many dyes or organic pollutant present in water.Photocatalysis is one of the advance oxidation processes,mainly carried out under irradiation of light and suitable photocatalytic materials.The photocatalytic activity of the photocatalytic materials mainly depends on the band gap,surface area,and generation of electron–hole pair for degradation dyes present in water.It has been observed that the surface area plays a major role in photocatalytic degradation of dyes,by providing higher surface area,which leads to the higher adsorption of dye molecule on the surface of photocatalyst and enhances the photocatalytic activity.This present review discusses the synergic effect of adsorption of dyes on the photocatalytic efficiency of various nanostructured high surface area photocatalysts.In addition,it also provides the properties of the water polluting dyes,their mechanism and various photocatalytic materials;and their morphology used for the dye degradation under irradiation of light along with the future prospects of highly adsorptive photocatalytic material and their application in photocatalytic removal of dye from waste water. | Subramanian Natarajan Hari C.Bajaj Rajesh J.Tayade | 2018 | Journal of Environmental Sciences2018，30，3： | 22 |
| 4 | 中国花生小核心种质与ICRISAT微核心种质的SSR遗传多样性比较显示文摘明确花生种质资源的遗传多样性和分布规律,对于发掘优良种质资源,选配优良亲本,拓宽育成品种的遗传基础具有重要意义。核心种质为种质资源的研究、评价和鉴定带来了方便。本研究从206对SSR引物中筛选26对引物对我国花生小核心种质和ICRISAT微核心种质共466份资源进行了遗传多样性分析,相似系数为0.49~0.99,鉴定出遗传差异最大的种质L2刚果(中国花生资源)与ICG12625(ICRISAT资源),相似系数为0.49。分析结果表明,多粒型花生的多态性信息量(0.761)和遗传多样性指数(0.97~1.11)均最大(平均相似系数最小,0.73~0.76),其次是普通型花生。中国花生种质资源与ICRISAT资源存在较大差异,尤其是ICRISAT的赤道型材料ICG12625,与中国花生资源的差异最大。相似系数和遗传多样性指数的分析结果均表明,我国花生种质资源的遗传多样性比ICRISAT资源丰富。 | 姜慧芳 任小平 张晓杰 黄家权 雷永 晏立英 廖伯寿 Hari D UPADHYAYA Corley C HOLBROOK | 2010 | 作物学报2010，36，7： | 19 |
| 5 | Mesozoic-Cenozoic extension of the Bohai Sea: contribution to the destruction of North China Craton显示文摘Bohai 海是位于东方诺思中国 Craton (NCC ) 的盆山脉系统的一个迟了的中生代新生代特征。岩石圈变瘦的迟了的中生代表明 NCC 的早破坏。破坏的发作由于 craton 的厚岩石圈的分层,在 Tanlu 差错地区以内向西在在军队飞机安排由趋势 NW grabens,并且由趋势 NNE grabens 代表了到 Tanlu 差错。迟了的中生代趋势 NW grabens 被与新生代趋势 NE 拉开盆有关的结构在东方 NCC 与很厚的中生代新生代沉积套印。生长差错和延期因素的 C 频率图([贝它]) 四,越过盆的节建议延期从边缘移居了到 Bohai 海的中心,并且为 Bohai 海的中生代和新生代延期因素比边缘的高。这些证据建议最大的延期发生在 Bohai 海的中心,它与在海的中心被发现的最薄的外壳一致。延期比率和 Bohai 海的构造进化建议它是为 NCC 的破坏的关键区域,由地形学证实了。然而, NCC 与与东北亚洲的构造政体有关的迟了的阶段经历了破坏的二个阶段[出版摘要] | Guiting HOU K. R. HARI | 2014 | Frontiers of Earth Science2014，8，2： | 14 |
| 6 | A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C显示文摘 | Chun-Tao Wai Joel K. Greenson Robert J. Fontana John D. Kalbfleisch Jorge A. Marrero Hari S. Conjeevaram Anna S.-F. Lok | 2003 | Hepatology2003，，2： | 11 |
| 7 | Glucosamine and chondroitin for the treatment of osteoarthritis显示文摘The prevalence of primary or idiopathic osteoarthritis(OA) of knee and hip joints has substantially increased in general population during the last decades. Analgesics and non-steroidal anti-inflammatory drugs are currently extensively used as non-surgical treatmentoptions. However, they act as symptomatic treatments, not offering a cure of OA and they are accused for an increased risk of adverse events. Glucosamine(GL) and chondroitin(CH) are nutritional supplements that have recently gained widespread use as treatment options for OA. They potentially or theoretically act as chondroprotectors or/and as 'disease-modifying OA drugs' offering not only symptomatic relief but also alteration of the natural history of OA. However, although many studies have showed a significant treatment effect, accompanied with remarkable safety, there is still controversy regarding their relative effectiveness compared with placebo or other treatments. The scope of this review is to present and critically evaluate the current evidence-based information regarding the administration of GL and CH for the treatment of knee or hip OA. Our focus is to investigate the clinical efficacy and safety after the use of these supplements. An effect of GL and CH on both clinical and radiological findings has been shown. However, only a few high-quality level I trials exist in the literature, especially on the assessment of radiological progression of OA. The effect sizes are generally small and probably not clinically relevant. Even the validity of these results is limited by the high risk of bias introduced in the studies. Both GL and CH seem to be safe with no serious adverse events reported. There is currently no convincing information for the efficacy of GL and CH on OA. | Haris S Vasiliadis Konstantinos Tsikopoulos | 2017 | World Journal of Orthopedics2017，8，1： | 10 |
| 8 | Diversity and trait-specific sources for productivity and nutritional traits in the global proso millet(Panicum miliaceum L.) germplasm collection显示文摘Proso millet is an important short-duration crop that adapts well to varied climatic conditions and is grown worldwide for food,feed and fodder purposes.Owing to a lack of genetic improvement,the crop has experienced no yield improvement and provides low income to farmers.In this study,200 accessions of proso millet originating in 30 countries were evaluated in two rainy seasons to assess phenotypic diversity for morpho-agronomic and grain nutritional traits and to identify high grain-yielding and grain nutrient-rich accessions.Proso millet diversity was structured by geographical region,by country within region,and by racial group.Race patentissimum showed high diversity and ovatum low diversity,and diverged widely from each other.The lowest divergence was observed between races compactum and ovatum.Eighteen high grain-yielding,10 large-seeded,and 26 two or more grain nutrients-rich accessions were identified,and highly diverse pairs of accessions within and between trait groups were identified.They included IPm 9 and IPm2661 for high grain yield and large seed size;and IPm 2069,IPm 2076,and IPm 2537 for high Fe,Zn,Ca,and protein contents.IPm 2875 had a seed coat that is readily removed by threshing.This study provides valuable information to proso millet researchers about agronomic and nutritional traits in accessions that could be tested for regional adaption and yield for direct release as cultivars,and could be used in breeding for developing high grain-yielding and nutrient-rich cultivars. | Mani Vetriventhan Hari D.Upadhyaya | 2018 | The Crop Journal2018，6，5： | 9 |
| 9 | Enhanced recovery after surgery protocol enhances early postoperative recovery after pancreaticoduodenectomy显示文摘Background: Enhanced recovery after surgery(ERAS) protocol is a multimodal, multidisciplinary and evidence-based approach to reduce surgical stress and enhance recovery in the postoperative period. This study aimed to analyze the outcome of ERAS protocol in patients after pancreaticoduodenectomy(PD). Methods: A total of 50 consecutive patients with pancreatic/periampullary cancer who underwent PD between January 2016 to August 2017 were included in the study. As per the institute ERAS protocol, nasogastric tube(NGT) was removed on postoperative day(POD) 1 if output was less than 200 mL and oral sips were allowed; oral liquids were allowed on POD2; semisolid diet by POD3; abdominal drain was removed on POD 4 if output was less than 100 mL with no evidence of postoperative pancreatic fistula(POPF); normal diet was allowed on POD5. Discharge criteria on POD6 were afebrile, tolerating oral normal diet, pain free and no surgery related complications(defined as per the ISGPS definitions). Results: NGT was removed on POD1 in 45(90%) patients, abdominal drain removed by POD4 in 41(82%) and 43(86%) patients were discharged on POD6. There was no 30-day postoperative mortality. Three(6%) patients had delayed gastric emptying(DGE). None had postoperative hemorrhage and POPF. Readmission rate was 8%. A significant relation was found between the length of hospital stay(LOS) with age( P < 0.05) and a marginal relation between LOS and postoperative albumin( P = 0.05). Conclusions: ERAS protocol can be safely followed in the perioperative care of patients who undergo PD. Early removal of NGT and allowing oral diet restore bowel function early. ERAS decreases the LOS and postoperative complications. | Ramasamy Mahendran Mallika Tewari Vinod Kumar Dixit Hari Shankar Shukla | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，2： | 9 |
| 10 | Numerical simulation to evaluate gas diffusion of turbulent flow in mine ventilation system显示文摘Tracer gas technique is a method to analyze the airflow path, measure the airflow quantity, and detect any recirculation or leakages in underground mine. In addition, it is also possible to evaluate the axial gas diffusion of gas in turbulent bulk flow by utilizing the tracer gas data. This paper discussed about the measurement using tracer gas technique in Cibaliung Underground Mine, Indonesia and the evaluation of effective axial diffusion coefficient, E, by numerical simulation. In addition, a scheme to treat network flow in mine ventilation system was also proposed. The effective axial diffusion coefficient for each airway was evaluated based on Taylor's theoretical equation. It is found that the evaluated diffusion coefficient agrees well with Taylor's equation by considering that the wall friction factor, f, is higher than those for smooth pipe flow. It also shows that the value of effective diffusion coefficient can be inherently determined and the value is constant when matching with other measurements. Furthermore, there are possibilities to utilize the tracer gas measurement data to evaluate the airway friction factors. | Arif Widiatmojo Kyuro Sasaki Nuhindro Priagung Widodo Yuichi Sugai Johannes Sinaga Haris Yusuf | 2013 | International Journal of Mining Science and Technology2013，23，3： | 8 |
| 11 | A comprehensive review on hybrid electric vehicles: architectures and components显示文摘The rapid consumption of fossil fuel and increased environmental damage caused by it have given a strong impetus to the growth and development of fuelefficient vehicles. Hybrid electric vehicles (HEVs) have evolved from their inchoate state and are proving to be a promising solution to the serious existential problem posed to the planet earth. Not only do HEVs provide better fuel economy and lower emissions satisfying environmental legislations, but also they dampen the effect of rising fuel prices on consumers. HEVs combine the drive powers of an internal combustion engine and an electrical machine. The main components of HEVs are energy storage system, motor, bidirectional converter and maximum power point trackers (MPPT, in case of solar-powered HEVs). The performance of HEVs greatly depends on these components and its architecture. This paper presents an extensive review on essential components used in HEVs such as their architectures with advantages and disadvantages, choice of bidirectional converter to obtain high efficiency, combining ultracapacitor with battery to extend the battery life, traction motors’ role and their suitability for a particular application. Inclusion of photovoltaic cell in HEVs is a fairly new concept and has been discussed in detail. Various MPPT techniques used for solar-driven HEVs are also discussed in this paper with their suitability. | Krishna Veer Singh Hari Om Bansal Dheerendra Singh | 2019 | Journal of Modern Transportation2019，27，2： | 8 |
| 12 | Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy显示文摘Colorectal cancer(CRC)is a predominant life-threatening cancer,with liver and peritoneal metastases as the primary causes of death.Intestinal inflammation,a known CRC risk factor,nurtures a local inflammatory environment enriched with tumor cells,endothelial cells,immune cells,cancer-associated fibroblasts,immunosuppressive cells,and secretory growth factors.The complex interactions of aberrantly expressed cytokines,chemokines,growth factors,and matrix-remodeling enzymes promote CRC pathogenesis and evoke systemic responses that affect disease outcomes.Mounting evidence suggests that these cytokines and chemokines play a role in the progression of CRC through immunosuppression and modulation of the tumor microenvironment,which is partly achieved by the recruitment of immunosuppressive cells.These cells impart features such as cancer stem cell-like properties,drug resistance,invasion,and formation of the premetastatic niche in distant organs,promoting metastasis and aggressive CRC growth.A deeper understanding of the cytokineand chemokine-mediated signaling networks that link tumor progression and metastasis will provide insights into the mechanistic details of disease aggressiveness and facilitate the development of novel therapeutics for CRC.Here,we summarized the current knowledge of cytokine-and chemokine-mediated crosstalk in the inflammatory tumor microenvironment,which drives immunosuppression,resistance to therapeutics,and metastasis during CRC progression.We also outlined the potential of this crosstalk as a novel therapeutic target for CRC.The major cytokine/chemokine pathways involved in cancer immunotherapy are also discussed in this review. | Ajaz A.Bhat Sabah Nisar Mayank Singh Bazella Ashraf Tariq Masoodi Chandra P.Prasad Atul Sharma Selma Maacha Thasni Karedath Sheema Hashem Syed Besina Yasin Puneet Bagga Ravinder Reddy Michael P.Frennaux Shahab Uddin Punita Dhawan Mohammad Haris Muzafar A.Macha | 2022 | Cancer Communications2022，42，8： | 8 |
| 13 | Anti-HBc screening in Indian blood donors:Still an unresolved issue显示文摘AIM:To study the seroprevalence of antibody to hepatitis B core antigen (anti-HBc) in healthy blood donors negative for HBsAg and to evaluate whether anti-HBc detection could be adopted in India as a screening assay for HBV in addition to HBsAg. METHODS: A total of 1700 serum samples collected from HBsAg-negative healthy blood donors were tested for the presence of anti-HBc antibody (IgM + IgG). All samples reactive for anti-HBc antibody were then investigated for presence of anti-HBs and for liver function tests (LFTs). One hundred serum samples reactive for anti-HBc were tested for HBV DNA by PCR method. RESULTS: Out of 1700 samples tested, 142 (8.4%) blood samples were found to be reactive for anti-HBc. It was signif icantly lower in voluntary (6.9%) as compared to replacement donors (10.4%, P = 0.011). Seventy- two (50.7%) anti-HBc reactive samples were also reactive for anti-HBs with levels > 10 mIU/mL and 70 (49.3%) samples were non-reactive for anti-HBs, these units were labeled as anti-HBc-only. These 142 anti-HBc reactive units were also tested for liver function test. HBV DNA was detected in only 1 of 100 samples tested. CONCLUSION: Keeping in view that 8%-18% of donor population in India is anti-HBc reactive, inclusion of anti- HBc testing will lead to high discard rate. Anti-HBs as proposed previously does not seem to predict clearance of the virus. Cost effectiveness of introducing universalanti-HBc screening and discarding large number of blood units versus considering ID NAT (Individual donor nuclic acid testing) needs to be assessed. | Hari Krishan Dhawan Neelam Marwaha Ratti Ram Sharma Yogesh Chawla Beenu Thakral Karan Saluja Sanjeev Kumar Sharma Manish K Thakur Ashish Jain | 2008 | World Journal of Gastroenterology2008，14，34： | 8 |
| 14 | Expression profile of cholecystokinin type-A receptor in gallbladder cancer and gallstone disease显示文摘BACKGROUND:Regulatory peptide receptors have attracted the interest of oncologists as a new promising approach for cancer pathology,imaging and therapy.Although cholecystokinin (CCK) is a potent modulator of gallbladder contractility and plays a potential role in pancreatic carcinogenesis through CCK type-A receptor (CCKAR),its role in gallbladder cancer (GBC) is still unknown and immunohistochemical detection of CCKAR in the gallbladder has not yet been reported.This novel case-control study aimed to investigate the expression profile of CCKAR in GBC and gallstone disease (GSD).METHODS:This study included 162 samples of gallbladder:94 from GBC and 68 from GSD.Expression of CCKAR was analyzed by immunohistochemistry and immunoblotting.The results were statistically correlated with disease history including age,sex,presence of gallstone,stage and differentiation.RESULTS:CCKAR was positive in 30/68 (44.1%) of GSD and 72/94 (76.6%) of GBC samples.Fifty-one of the 72 (70.8%) CCKAR-positive GBC samples showed over-expression.Interestingly,consistent results also appeared in the immunoblotting study.CONCLUSIONS:CCKAR expression was significantly increased in GBC compared to GSD.Moreover,CCKAR expression was associated with the degree of tumor differentiation,i.e.,less expression in poorly-differentiated tumors.Thus,it has future prognostic and therapeutic implications in the management of GBC. | Rajani Rai Mallika Tewari Mohan Kumar Tej Bali Singh Hari S Shukla | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，4： | 7 |
| 15 | Hepatocellular Carcinoma and the Role of Liver Transplantation:A Review显示文摘Hepatocellular carcinoma(HCC)is one of the leading causes of cancer deaths worldwide and liver transplantation(LT)is the only potentially curative treatment.Over the years,Milan criteria has been used for patient selection.There is ongoing research in this field with introduction of new biomarkers for HCC that can help guide future treatment.Furthermore,newer therapies for downstaging of the tumor are being implemented to prevent dropout from the transplant list.In addition,combination therapies for better outcome are under investigation.Interestingly,the concept of living-donor LT and possible use of hepatitis C virus-positive donors has been implemented as an attempt to expand the organ pool.However,there is a conflict of opinion between different centers regarding its efficacy and data is scarce.The aim of this review article is to outline the various selection criteria for LT,discuss the outcomes of LT in HCC patients,and explore future directions of LT for HCC.Therefore,a comprehensive PubMed/MEDLINE review was conducted.To expand our search,references of the retrieved articles were also screened for additional data.After selecting the studies,the authors independently reviewed them to identify the relevant studies.After careful evaluation 120 studies relevant to out topic are cited in the manuscript.Three tables and two figures are also included.In conclusion LT for HCC has evolved over the years.With the introduction of several expanded criteria beyond Milan,the introduction of bridging therapies,such as transcatheter arterial chemoembolization and radiofrequency ablation,and the approval of newer systemic therapies,it is evident that there will be more LT recipients in the future.It is promising to see ongoing trials and the continuous evolution of protocols.Prospective studies are needed to guide the development of a pre-LT criteria that can ensure low HCC recurrence risk and is not overly stringent,clarify the role of LDLT,and determine the optimal bridging therapies to LT. | Haris Muhammad Aniqa Tehreem Peng-Sheng Ting Merve Gurakar Sean Young Li Cem Simsek Saleh A.Alqahtani Amy K.Kim Ruhail Kohli Ahmet Gurakar | 2021 | Journal of Clinical and Translational Hepatology2021，9，5： | 7 |
| 16 | 利用核心种质发掘及评价花生抗黄曲霉资源显示文摘黄曲霉菌极大地限制全世界的花生生产和产业发展,且生产上抗性品种较少,我国花生育种和生产中的抗性资源缺乏,迫切需要发掘抗黄曲霉种质。本研究以中国花生核心种质561份和ICRISAT微核心种质155份为材料,鉴定了黄曲霉侵染和产毒抗性,发掘出抗黄曲霉侵染和产毒种质各8份,包括具优良农艺性状的抗黄曲霉产毒种质51002-6。鉴定结果表明,ICRISAT花生微核心种质中抗黄曲霉侵染和产毒种质的频率高于中国花生核心种质;普通型花生资源中抗黄曲霉侵染种质的频率较高,龙生型资源中抗黄曲霉产毒种质的频率较高。根据SSR分析,鉴定出与生产上推广应用的优良品种中花5号、中花6号、中花12和远杂9102遗传距离较远的抗黄曲霉产毒种质ICG12625和抗侵染种质ICG4750,拓宽了我国花生品种改良的遗传基础。根据抗病基因产物的NBS类型保守域设计简并引物对抗黄曲霉种质的DNA进行PCR扩增、克隆、测序和分析,获得了1条RGA片段。 | 姜慧芳 任小平 王圣玉 张晓杰 黄家权 廖伯寿 Corley C HOLBROOKA Hari D UPADHYAYA | 2010 | 作物学报2010，36，3： | 6 |
| 17 | Practical approaches to effective management of intestinal radiation injury:Benefit of resectional surgery显示文摘AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management.METHODS:During a 7-year period we operated on 17 cases (5 male,12 female) admitted to our surgical department with intestinal radiation injury (IRI).They were originally treated for a pelvic malignancy by surgical resection followed by postoperative radiotherapy.During follow-up,they developed radiation enteritis requiring surgical treatment due to failure of conservative management.RESULTS:IRI was located in the terminal ileum in 12 patients,in the rectum in 2 patients,in the descending colon in 2 patients,and in the cecum in one patient.All patients had resection of the affected region(s).There were no postoperative deaths,while 3 cases presented with postoperative complications (17.7%).All patients remained free of symptoms without evidence of recurrence of IRI for a median follow-up period of 42 mo (range,6-96 mo).CONCLUSION:We report a favorable outcome without IRI recurrence of 17 patients treated by resection of the diseased bowel segment. | Nikolaos Perrakis Evangelos Athanassiou Dimitra Vamvakopoulou Maria Kyriazi Haris Kappos Nikolaos C Vamvakopoulos Iakovos Nomikos | 2011 | World Journal of Gastroenterology2011，17，35： | 6 |
| 18 | 中国甘肃和青海省叶蜂类六新种记述(膜翅目:叶蜂科)(英文)显示文摘记述了叶蜂科采自甘肃的 3个新种:Tenthredo (Tenthredo) sinotemula sp. nov., Tenthredo (Tenthredella) labrangensis sp. nov.和 Tenthredo (Tenthredella) sinosimplex sp. nov.;采自青海的 3 个新种:Tenthredo (Tenthredella) rolleri sp. nov., Tenthredo (Tenthredella) qinghaiensis sp. nov.和 Tenthredo (Tenthredella) yunningsiensis sp. nov. | Attila Haris | 2009 | Zoological Research2009，30，3： | 6 |
| 19 | WJSC 6^(th) Anniversary Special Issues(1):Hematopoietic stem cell transplantation Allogeneic hematopoietic cell transplant for acute myeloid leukemia:Current state in 2013 and future directions显示文摘Acute myeloid leukemia(AML)represents a heterogeneous group of high-grade myeloid neoplasms of the elderly with variable outcomes.Though remissioninduction is an important first step in the management of AML,additional treatment strategies are essential to ensure long-term disease-free survival.Recent pivotal advances in understanding the genetics and molecular biology of AML have allowed for a risk-adapted approach in its management based on relapse-risk.Allogeneic hematopoietic cell transplantation(allo-HCT)represents an effective therapeutic strategy in AML providing the possibility of cure with potent graft-versus-leukemia reactions,with a demonstrable survival advantage in younger patients with intermediate-or poor-risk cytogenetics.Herein we review the published data regarding the role of allo-HCT in adults with AML.We searched MEDLINE/PubMed and EMBASE/Ovid.In addition,we searched reference lists of relevant articles,conference proceedings and ongoing trial databases.We discuss the role of allo-HCT in AML patients stratified by cytogenetic-and molecular-risk in first complete remission,as well as allo-HCT as an option in relapsed/refractory AML.Besides the conventional sibling and unrelated donor allografts,we review the available data and recent advances for alternative donor sources such as haploidentical grafts and umbilical cord blood.We also discuss conditioning regimens,including reduced intensity conditioning which has broadened the applicability of allo-HCT.Finally we explore recent advances and future possibilities and directions of allo-HCT in AML.Practical therapeutic recommendations have been made where possible based on available data and expert opinion. | Abraham S Kanate Marcelo C Pasquini Parameswaran N Hari Mehdi Hamadani | 2014 | World Journal of Stem Cells2014，6，2： | 6 |
| 20 | Differential Sensitivity of Macrocarpa and Microcarpa Types of Chickpea (Cicer arietinum L.) to Water Stress: Association of Contrasting Stress Response with Oxidative Injury显示文摘Chickpea (Cicer arietinum L.) 是特别地敏感的在它的繁殖阶段浇应力并且在水应力的条件下面,将放弃花和豆荚,因此减少收益潜力。有 chickpea 的二种类型:(i) Macrocarpa (Kabuli ) 它有大,击打塑造头的、轻棕色的种子;并且(ii ) Microcarpa (Desi ) 它有小、尖、黑暗褐的种子。相对说, Kabuli 被报导了更敏感比 Desi 浇应力。与对比敏感流水联系的内在的机制在新陈代谢的水平强调井没被理解。我们假设了一个原因因为在 chickpea 的二种类型的形成对照的水压力敏感可以是在氧化损害的一个变化。在现在的学习,两种类型的植物是为 14 d 在繁殖舞台强调的水。由于压力, Kabuli 类型与为 Desi 类型观察的 64% 减小相比在控制上在种子产量展出了 80% 减小。在叶水潜力(w) 的减少与 Desi 类型相比在 Kabuli 是更快的。在水压力时期的结束, w 被归结为 ? 2.9 并且 ? 分别地,没有他们之间的任何重要差别,在 Desi 和 Kabuli 的 3.1 MPa 打字。在应力的最后一天, Kabuli 比 Desi 经历了 20% 更多的膜损害。叶绿素内容和光合的率与 Kabuli 相比在 Desi 是显著地更大的。malondialdehyde 和 H2O2 内容与 Desi 相比在在 Kabuli 的水压力的结束是显著地更高的,显示在前者的更大的氧化应力。抗氧化剂的层次例如维生素酸和谷胱甘肽,比 Kabuli 在 Desi 是显著地更高的。, Superoxide dismutase 和过氧化氢酶活动没在第 10 天, ascorbate peroxidase 的活动, dehydroascorbate reductase,和谷胱甘肽 reductase 在 chickpea 的二种类型之间显著地不同在 Desi 是更高的。这些调查结果显示在 Desi 类型的更大的应力公差可以被归功于到它维持更好的水地位的优异能力,它导致更少的氧化损坏。另外,实验室研究由使 chickpea 的两种类型遭到到聚乙烯的类似的层次进行了导致乙二醇的水应力并且到 10 .mol/L abscisic,酸显示了 Desi 类型的一个更大的能力比 Kabuli 类型处理氧化应力。 | Harsh Nayyar Smita Singh Satwinder Kaur Sanjeev Kumar Hari D. Upadhyaya | 2006 | Journal of Integrative Plant Biology2006，48，11： | 6 |
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