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| 1 | 恶意的腹水: 预示的因素, pathophysiology 和治疗学的措施的评论显示文摘 Malignant ascites indicates the presence of malignant cells in the peritoneal cavity and is a grave prognostic sign. While survival in this patient population is poor, averaging about 20 wk from time of diagnosis, quality of life can be improved through palliative procedures. Selecting the appropriate treatment modality remains a careful process, which should take into account potential risks and benefits and the life expectancy of the patient. Traditional therapies, including paracentesis, peritoneovenous shunt placement and diuretics, are successful and effective in varying degrees. After careful review of the patient’s primary tumor origin, tumor biology, tumor stage, patient performance status and comorbidities, surgical debulking and intraperitoneal chemotherapy should be considered if the benefit of therapy outweighs the risk of operation because survival curves can be extended and palliation of symptomatic malignant ascites can be achieved in select patients. In patients with peritoneal carcinomatosis who do not qualify for surgical cytoreduction but suffer from the effects of malignant ascites, intraperitoneal chemotherapy can be safely and effectively administered via laparoscopic techniques. Short operative times, short hospital stays, low complication rates and ultimately symptomatic relief are the advantages of laparoscopically administering heated intraperitoneal chemotherapy, making it not only a valuable treatment modality but also the most successful treatment modality for achieving palliative cure of malignant ascites. | Suma L Sangisetty Thomas J Miner | 2012 | World Journal of Gastrointestinal Surgery2012，4，4： | 45 |
| 2 | Studies on thermoresponsive polymers:Phase behaviour,drug delivery and biomedical applications显示文摘The present review aims to highlight the applications of thermoresponsive polymers.Thermo-responsive polymers show a sharp change in properties upon a small or modest change in temperature.This behaviour can be utilized for the preparation of so-called‘smart’drug delivery systems,which mimic biological response behaviour to a certain extent.Such materials are used in the development of several applications,such as drug delivery systems,tissue engineering scaffolds and gene delivery.Advances in this field are particularly relevant to applications in the areas of regenerative medicine and drug delivery.This review addresses summary of the main applications of thermoresponsive polymers which are categorized based on their 3-dimensional structure;hydrogels,interpenetrating networks,micelles,films and particles.The physico-chemical behaviour underlying the phase transition is also discussed in brief. | Arijit Gandhi Abhijit Paul Suma Oommen Sen Kalyan Kumar Sen | 2015 | Asian Journal of Pharmaceutical Sciences2015，10，2： | 9 |
| 3 | Factors affecting residual exotropia after two muscle surgery for intermittent exotropia显示文摘AIM: To study the factors affecting residual exotropia(>10 PD) at 4-6wk postoperative visit following two rectus muscle surgery for intermittent exotropia [bilateral lateral rectus(LR) recession or unilateral recess resect procedure].METHODS: A retrospective chart review of patients with intermittent exotropia ≤50 PD who underwent two rectus muscle surgery in between Jan. 2011 to Dec. 2013 was performed. Possible factors were compared between patients with residual exotropia(>10 PD) and successful outcome(within 10 PD of orthotropia) at the 4-6wk postoperative visit. Effect/dose ratio was calculated by dividing the effect of surgery by the total amount(mm) of muscle surgery done.RESULTS: One hundred and fifty-seven patients with mean age of 14y(range 3-53y) were included. Twentyseven patients(17.2%) had residual exotropia at 4-6wk postoperative follow up. Age at surgery(P=0.009) and preoperative deviation for distance(P≤0.001) and near(P=0.001) were identified as important predictors of unsuccessful outcome. The occurrence of residual exotropia was not affected by amblyopia, anisometropia, lateral incomitance, pattern deviation, vertical deviation, type of exotropia or type of surgery done(recess-resect or bilateral LR recession). The effect/dose ratio was more in deviations >40 PD in the both recess-resect and bilateral LR recession type of surgery. The effect/dose ratio was less in patients with residual exotropia as compared to the successful outcome group(1.36 PD/mm vs 2.05 PD/mm in the bilateral LR recession surgery and 1.93 PD/mm vs 2.63 PD/mm in the unilateral recess-resect surgery).CONCLUSION: Residual exotropia is seen in 17% of patients after two muscle surgery for intermittent exotropia. Patients with older age and larger preoperative deviation have greater chances of developing failure of two muscle strabismus surgery for intermittent exotropia. | Shailja Tibrewal Nishtha Singh Marazul Islam Bhuiyan Suma Ganesh | 2017 | International Journal of Ophthalmology(English edition)2017，10，7： | 3 |
| 4 | Interaction of repaglinide with bovine serum albumin:Spectroscopic and molecular docking approaches显示文摘Repaglinide (RPG) regulates the amount of glucose by stimulating the pancreas to release insulin in the blood. In view of its biological importance, we have examined the interaction between RPG and a model protein, bovine serum albumin (BSA) employing various spectroscopic, electrochemical and molecular docking methods. Fluorescence spectra of BSA were recorded in the presence and absence of RPG in phosphate buffer of pH 7.4. Fluorescence intensity of BSA was decreased upon the addition of increased concentrations of RPG, indicating the interaction between RPG and BSA. Stern-Volmer quenching analysis results revealed that RPG quenched the intensity of BSA through dynamic quenching mechanism. This was further confirmed from the time-resolved fluorescence measurements. The binding constant as calculated from the spectroscopic and voltammetric results was observed to be in the order of 104M-1 at 298 K, suggesting the moderate binding affinity between RPG and BSA. Competitive experimental results revealed that the primary binding site for RPG on BSA was site II. Absorption and circular dichroism studies indicated the changes in the secondary structure of BSA upon its interaction with RPG. Molecular simulation studies pointed out that RPG was bound to BSA in the hydrophobic pocket of site II. | Suma K.Pawar Seetharamappa Jaldappagari | 2019 | Journal of Pharmaceutical Analysis2019，9，4： | 2 |
| 5 | Spent residue from cumin – a potential source of dietary fiber显示文摘 | H.B. Sowbhagya P. Florence Suma S. Mahadevamma R.N. Tharanathan | 2007 | Food Chemistry2007，，3： | 2 |
| 6 | Low dielectric loss PTFE/CeO2 ceramic composites for microwave substrate applications显示文摘 | ANJANA P S SEBASTIAN M T SUMA J | 2008 | Applied Ceramic Technology2008，5，2： | 1 |
| 7 | Color Doppler US in the evaluation of uterine vascular abnormalities显示文摘 | Polat P Suma S Kantarcy M | 2002 | Radiographics2002，22，1： | 1 |
| 8 | High resolution protein separations using affinity ultrafiltration with small charged Iigands显示文摘 | Suma Rao Andrew L Zydney | 2006 | Journal of Membrane Science2006，280，9： | 1 |
| 9 | Industry Associations and Technology-based Growth in India显示文摘 | Athreye Suma Chaturvedi Sachin | | 0，，01： | 1 |
| 10 | Identification of tropomyosins as major allergens in Antarctic krill and mantis shrimp and their amino acid sequence characteristics显示文摘 | Motoyama K Suma Y Ishizaki S | | 0，，06： | 1 |
| 11 | Nontransplant cardiac surgery for end-stage cardiomyopathy显示文摘 | Isomura T Horii T | 2000 | J Thorac Cardiovasc Surg2000，119，： | 1 |
| 12 | Induction of tumor necrosis factor by a camptothecin derivative,irinotecan,in mice and human mononuclear cells显示文摘 | Goto S Okutomi T Suma Y | | 0，，： | 1 |
| 13 | The efficacy of non-contrast helical computed tomography in the prediction of urinary stone composition in vivo显示文摘 | Demirel A Suma S | 2003 | J Int Med Res2003，31，1： | 1 |
| 14 | Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astrogliol reactions in rat bippocampus following traumatic brain injury显示文摘 | Suma T Koshinaga M Fukushima M | 2008 | Neurol Res2008，30，4： | 1 |
| 15 | Antibacterial potential of garlic - derived allicin and its cancellation by sulf-hydryl compounds 显示文摘 | Fujisawa H Watanabe K Suma K | 2009 | Biosci Biotechnol Biochem2009，739，： | 1 |
| 16 | Antibacterial potential of garlic-derived allicin and its cancellation by sulf- hydryl compounds 显示文摘 | FUJISAWA H WATANABE K SUMA K | 2009 | Biosci Biotechnol Biochem2009，73，9： | 1 |
| 17 | Posttransplant Administration of Donor Leukocytes Induces Long- Term Acceptance of Kidney or Liver Transplants by an Activation-Associated Immune Mechanism 显示文摘 | Yiqun Yan Suma Shastry Craig Richards | 2001 | The Journal of Immunology2001，166，： | 1 |
| 18 | Selected ventrieuloplasty for id- iopathic dilated eardiomyopathy with advanced congestive heart fail- ure: midterm results and risk analysis显示文摘 | Suma H Tanabe H Uejima T | 2007 | Eur J Cardiothorae Surg2007，32，6： | 1 |
| 19 | Isolation of endophytic bacteria producing the anti-cancer alkaloid camptothecine from Miquelia dentata Bedd. (Icacinaceae)显示文摘 | S. Shweta J. Hima Bindu J. Raghu H.K. Suma B.L. Manjunatha P. Mohana Kumara G. Ravikanth K.N. Nataraja K.N. Ganeshaiah R. Uma Shaanker | 2013 | Phytomedicine2013，，10： | 1 |
| 20 | Competition, Rivalry and Innovative Behavlout 显示文摘 | ATHREYE SUMA S | 2001 | Economics of Innovation & New Technology2001，10，1： | 1 |
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