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| 1 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021，29，5： | 15 |
| 2 | The mRNA Expression Profiles of Five Heat Shock Protein Genes from Frankliniella occidentalis at Different Stages and Their Responses to Temperatures and Insecticides显示文摘The western flower thrips, Frankliniella occidentalis(Pergande) is a highly invasive pest that is able to exploit many crops across a wide range of environmental conditions. Five full-length cDNAs of heat shock protein(HSP) genes(Fo-HSP90, Fo-HSP70, Fo-HSP60, Fo-HSP40 and Fo-HSP28.9) were cloned from F. occidentalis, and their expression profiles were investigated under conditions of thermal stress and insecticide exposure, and at different stages during development, using real-time quantitative PCR. All five gene sequences showed high similarity to homologs in other species, indicating the conserved function of this gene family. HSP60 represents an informative phylogenetic marker at the ordinal taxonomic level within Insecta, but HSP90, which has two homologous copies in Hymenoptera, was not informative. T he expression of Fo-HSPs under thermal stress suggests that Fo-HSP90, Fo-HSP70, and Fo-HSP28.9 are inducible by both cold and heat stress, Fo-HSP40 is only heat-inducible, and Fo-HSP60 is thermally insensitive. There were two patterns of cold induction of Fo-HSPs: one is from 0 to 4°C and the other is around-8°C. All five Fo-HSPs genes were induced by exposure to sublethal concentrations of the insecticide avermectin. The expression of the five Fo-HSPs during different developmental stages suggests that they all play a role in development of F. occidentalis. | WANG Hai-hong Stuart R Reitz WANG Li-xia WANG Shuai-yu LI Xue LEI Zhong-ren | 2014 | Journal of Integrative Agriculture2014，13，10： | 10 |
| 3 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 4 | Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells显示文摘 | Saiyong Zhu Raiesh Ambasudhan Woong Sun Hyun Jung Kim Maria Talantova Xiaojing Wang Mingliang Zhang Yu Zhang Timothy Laurent James Parker Han-Seop Kim Jeffrey D Zaremba Sofiyan Saleem Sara Sanz-Blasco Eliezer Masliah Scott R McKercher Yee Sook Cho Stuart A Lipton Janghwan Kim Sheng Ding | 2014 | Cell Research2014，24，1： | 6 |
| 5 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 6 | Complications and monitoring of OKT3 therapy 显示文摘 | Thistlethwaite J R Stuart J K Mayes J T | 1998 | AM J Kidney Dis1998，11，2： | 2 |
| 7 | Tensile Testing of EP-823 and HT-9 After Irradiation in STIP Ⅱ 显示文摘 | Maloy Stuart A Romero T James M R | 2006 | Journal of Nuclear Materials2006，356，123： | 1 |
| 8 | NEMO Satellite Sensor Imaging Payload 显示文摘 | Myers W A Smith R D Stuart J L | 1998 | Proceeding of SPIE1998，3437，： | 1 |
| 9 | X-ray diffraction estimation of the microfibril angle variation in eucalypt wood显示文摘 | Stuart S Evans R | 1994 | Appita1994，48，3： | 1 |
| 10 | Impact of Entrepreneurial Management Experience on Early Performance 显示文摘 | STUART R W ABETTI P A | 1990 | Journal of Business Venturing1990，5，3： | 1 |
| 11 | Embrittlement of Irradiated Ferritic/Martensitic Steels in the Absence of Irra diation Hardening 显示文摘 | Maloy Stuart A Romero T James M R | 2008 | Journal of Nuclear Materials2008，377，3： | 1 |
| 12 | The competence of top team members: A frame-work for successful performance 显示文摘 | Thompson J E Stuart R Lindsay P R | 1996 | Journal of Managerial Psychology1996，11，3： | 1 |
| 13 | Effectual Versus Predictive Logics in Entrepreneur-ial Decision-making:Differences between Expertsand Novices显示文摘 | NICHOLAS D STUART R SARAS D S | 2008 | Journal of Business Venturing2008，26，3： | 1 |
| 14 | Changes in global gene expression patterns during development and maturation of the rat kidney显示文摘 | Stuart R O Bush K T Nigam S K | 2001 | Proc Natl Acad Sci U S A2001，98，10： | 1 |
| 15 | Diagonally Scaled Permutations and Circulant Matrices 显示文摘 | STUART J L WEAVER J R | 1994 | Linear Algebra Appl1994，212，15： | 1 |
| 16 | Using wind anomalies to forecast east coast winter storms显示文摘 | STUART N A GRUMM R H | | 0，，06： | 1 |
| 17 | Targeted Resequencing Reveals ALK Fusions in Non-Small Cell Lung Carcinomas Detected by FISH, Immunohistochemistry, and Real-Time RT-PCR: A Comparison of Four Methods显示文摘 | Katja Tuononen Virinder Kaur Sarhadi Aino Wirtanen Mikko R?nty Kaisa Salmenkivi Aija Knuuttila Satu Remes Aino I. Telaranta-Keerie Stuart Bloor Pekka Ellonen Sakari Knuutila Akanchha Kesari | 2013 | BioMed Research International2013，，： | 1 |
| 18 | Exponential mean- square stability of numerical solutions to stochastic differ- ential equations 显示文摘 | Higham D J Mao X R Stuart A M | 2003 | LMS Journal of Computation and Mathematics2003，6，： | 1 |
| 19 | Maleated Coupling Agents for Natural Fiber Composites 显示文摘 | T J Keener R K Stuart T K Brown | 2004 | Cmnposites Part A: Applied Science and Manufacturing2004，35，3： | 1 |
| 20 | Temperature dependence of the rate of reaction of OH with some aromatic compounds in aqueous solution 显示文摘 | Ashton L Buxtion G V Stuart C R | 1995 | J Chem Soe Faraday Trans1995，91，11： | 1 |
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