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| 1 | In vitro investigation of the effect of dairy propionibacteria on rumen pH,lactic acid and volatile fatty acids显示文摘Ruminal acidosis is a prevalent disorder in ruminants such as dairy cows and feedlot beef cattle, caused primarily by the inclusion of a high percentage of readily fermentable concentrates in the diet. The disorder presents as an accumulation of lactic acid, a decrease of p H in the rumen and a subsequent imbalance of the rumen fermentation process with detrimental impacts on the animal's health and productivity. Dairy propionibacteria, a group of bacteria characterised by utilization of lactic acid as the favoured carbon source, with propionic acid produced as a by-product, were evaluated in this study as potential direct-fed microbials for use in controlling ruminal acidosis. Acidosis was simulated by introduction of high concentrations of lactic acid into rumen fluid samples and a multi-strain in vitro analysis was conducted, whereby changes in p H and lactic acid metabolism were compared in identical acidified rumen samples, following inoculation with various propionibacteria. This was followed by a study to evaluate the effect of bacterial inoculation dosage on acid metabolism. The results indicated that lactic acid levels in the rumen fluid were significantly reduced, and propionic acid and acetic acid concentrations both significantly increased, following addition of propionibacteria. Significant ‘between strains' differences were observed, with Propionibacterium acidopropionici 341, Propionibacterium freudenreichii CSCC 2207, Propionibacterium jensenii NCFB 572 and P. jensenii 702 each producing more rapid reduction of lactic acid concentration than P. freudenreichii CSCC 2206, P. acidopropionici ATCC 25562 and Propionibacterium thoenii ATCC 4874. Furthermore, the efficacy of this application was dosage related, with the rates of reduction in lactic acid levels and production of propionic acid, both significantly greater for the higher(1010 cfu mL^(-1)) compared with lower(105 cfu mL^(-1)) dosage inoculation. The results confirmed that the introduction of propionibacteria could promote more rapid reduction of lactic acid levels than would occur without their addition, demonstrating their potential in controlling ruminal acidosis. | Jianbiao Luo Chaminda Senaka Ranadheera Stuart King Craig Evans Surinder Baines | 2017 | Journal of Integrative Agriculture2017，16，7： | 2 |
| 2 | Structure and receptor binding 显示文摘 | Jackson T King AM Stuart DI | 2003 | Virus Res2003，91，1： | 1 |
| 3 | Circulating insulin-like growth factor I levels in newborn premature and full-term infants followed longitudinally 显示文摘 | Lineham JD Smith RM Dahlenburg GW King RA Haslam RR Stuart MC | 1986 | Early Hum Dev1986，13，1： | 1 |
| 4 | Structure and receptor binding 显示文摘 | Jackson T King A M Stuart D I | 2003 | Virus Res2003，91，： | 1 |
| 5 | Structure and receptor binding 显示文摘 | Jackson T King A M Q Stuart D I | 2003 | Virus Res2003，91，： | 1 |
| 6 | Structure and receptor binding显示文摘 | JACKSON T KING A M STUART D I | 2003 | Virus Res2003，91，： | 1 |
| 7 | Structure and receptor binding显示文摘 | Jackson T King A M Q Stuart D I | 2003 | Virus Res2003，91，： | 1 |
| 8 | T follicular helper (TFH)cells in normal and dysregulated immune responses显示文摘 | CECILE KING STUART G TANG Y E | 2008 | Annu R ev Immunol2008，26，： | 1 |
| 9 | Growth and mortality are related to adult tree size in a Malaysian mixed dipterocarp forest显示文摘 | David A King Stuart J Davies Nur Supardi Md Noor | 2006 | Forest Ecology and Management2006，223，13： | 1 |
| 10 | Structure and receptor binding显示文摘 | Jackson T King A M Stuart D I | 2003 | Virus Res2003，91，： | 1 |
| 11 | Functional outcome of AO type C distal humeral fractures显示文摘 | Wade T. Gofton Joy C. MacDermid Stuart D. Patterson Ken J. Faber Graham J.W. King | 2003 | Journal of Hand Surgery2003，，2： | 1 |
| 12 | The Enterprise Ontology 显示文摘 | Mike Uschold Martin King Stuart Moralee Yannis Zorgios | 1998 | The Knowledge Engineering Review1998，13，1： | 1 |
| 13 | Structure and receptor binding 显示文摘 | Jackson T King A M Stuart D I | 2003 | Virus Res2003，91，： | 1 |
| 14 | Structure and receptor binding显示文摘 | Jackson T King A M Stuart D I | | 0，，01： | 1 |
| 15 | Structure and receptor binding显示文摘 | Jackson T King A M Stuart D I | 2003 | Virus2003，91，： | 1 |
| 16 | Structure and receptor binding显示文摘 | Jackson T King A M Stuart D I | 2003 | Virus Res2003，91，： | 1 |
| 17 | Acute Definitive Internal Fixation of Pelvic Ring Fractures in Polytrauma Patients: A Feasible Option显示文摘 | Natalie Enninghorst Laszlo Toth Kate L. King Debra McDougall Stuart Mackenzie Zsolt J. Balogh | 2010 | The Journal of Trauma: Injury, Infection, and Critical Care2010，，4： | 1 |
| 18 | Structure and receptor binding显示文摘 | Jackson T King AM Stuart D | 2003 | Virus Res2003，91，： | 1 |
| 19 | Effect of screw placement on fixation in the humeral head显示文摘 | Allan S.L. Liew James A. Johnson Stuart D. Patterson Graham J.W. King David G. Chess | 2000 | Journal of Shoulder and Elbow Surgery2000，，5： | 1 |
| 20 | Structure andreceptor binding 显示文摘 | JACKSON T KING AM STUART DI | 2003 | Virus Res2003，91，： | 1 |
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