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| 1 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021,29,5: | 15 |
| 2 | Multiphase computed tomography radiomics of pancreatic intraductal papillary mucinous neoplasms to predict malignancy显示文摘BACKGROUND Intraductal papillary mucinous neoplasms(IPMNs)are non-invasive pancreatic precursor lesions that can potentially develop into invasive pancreatic ductal adenocarcinoma.Currently,the International Consensus Guidelines(ICG)for IPMNs provides the basis for evaluating suspected IPMNs on computed tomography(CT)imaging.Despite using the ICG,it remains challenging to accurately predict whether IPMNs harbor high grade or invasive disease which would warrant surgical resection.A supplementary quantitative radiological tool,radiomics,may improve diagnostic accuracy of radiological evaluation of IPMNs.We hypothesized that using CT whole lesion radiomics features in conjunction with the ICG could improve the diagnostic accuracy of predicting IPMN histology.AIM To evaluate whole lesion CT radiomic analysis of IPMNs for predicting malignant histology compared to International Consensus Guidelines.METHODS Fifty-one subjects who had pancreatic surgical resection at our institution with histology demonstrating IPMN and available preoperative CT imaging were included in this retrospective cohort.Whole lesion semi-automated segmentation was performed on each preoperative CT using Healthmyne software(Healthmyne,Madison,WI).Thirty-nine relevant radiomic features were extracted from each lesion on each available contrast phase.Univariate analysis of the 39 radiomics features was performed for each contrast phase and values were compared between malignant and benign IPMN groups using logistic regression.Conventional quantitative and qualitative CT measurements were also compared between groups,viaχ2(categorical)and Mann Whitney U(continuous)variables.RESULTS Twenty-nine subjects(15 males,age 71±9 years)with high grade or invasive tumor histology comprised the'malignant'cohort,while 22 subjects(11 males,age 70±7 years)with low grade tumor histology were included in the'benign'cohort.Radiomic analysis showed 18/39 precontrast,19/39 arterial phase,and 21/39 venous phase features differentiated malignant from benign IPMNs(P<0.05).Multivariate analysis including only ICG criteria yielded two significant variables:thickened and enhancing cyst wall and enhancing mural nodule<5 mm with an AUC(95%CI)of 0.817(0.709-0.926).Multivariable post contrast radiomics achieved an AUC(95%CI)of 0.87(0.767-0.974)for a model including arterial phase radiomics features and 0.834(0.716-0.953)for a model including venous phase radiomics features.Combined multivariable model including conventional variables and arterial phase radiomics features achieved an AUC(95%CI)of 0.93(0.85-1.0)with a 5-fold cross validation AUC of 0.90.CONCLUSION Multi-phase CT radiomics evaluation could play a role in improving predictive capability in diagnosing malignancy in IPMNs.Future larger studies may help determine the clinical significance of our findings. | Stuart L Polk Jung W Choi Melissa J McGettigan Trevor Rose Abraham Ahmed Jongphil Kim Kun Jiang Yoganand Balagurunathan Jin Qi Paola T Farah Alisha Rathi Jennifer B Permuth Daniel Jeong | 2020 | World Journal of Gastroenterology2020,26,24: | 5 |
| 3 | Antioxidant activity and polyphenol and procyanidin contents of selected commercially available cocoa-containing and chocolate products in the United States 显示文摘 | Miller K B Stuart D A Smith N L | 2006 | J Agric Food Chem2006,54,: | 1 |
| 4 | Technical efficiency evaluation of logging contractors using a nonparametric model 显示文摘 | Lebel L G Stuart W B | 1998 | International Journal of Forest Engineering1998,9,2: | 1 |
| 5 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014,12,: | 1 |
| 6 | Femtosecond pulsed laser ablation of metal alloy and semiconductor largets显示文摘 | TRELENBERG T W DINH L N STUART B C | 2004 | Applied Surjace Science2004,229,: | 1 |
| 7 | A rapid indirect ELISA for the serigrouping of Australian orbiviruses 显示文摘 | Ross A L | 1994 | Journal of Virological Methods1994,49,: | 1 |
| 8 | Technical efficiency evaluation of logging contractors using a nonparametric mode 1 显示文摘 | LEBEL L G STUART W B | 1998 | Inter Journal of Forest Engineering1998,9,2: | 1 |
| 9 | EnaR: An R package for ecosystem network analysis 显示文摘 | STUART R B MATTHEW K L | 2014 | Methods in Ecology and Evolution2014,5,: | 1 |
| 10 | Technical efficiency evaluation of logging contractors using a nonparametric model 显示文摘 | LeBel L G and Stuart W B | 1998 | Inter J of Forest Engineering1998,9,2: | 1 |
| 11 | Varietal and envi- ronmental variations in ( 1 - 3,1 - 4) - 13 - gjucan lev- els and ( 1 - 3,1 - 4 ) - 13 - glucanase potential in bar- ley: relationships tomalting quality 显示文摘 | STUART I M LOI L FINCHER G B | 1988 | Journal of Cere- al Science1988,7,: | 1 |
| 12 | Alrerations in cellular proliferation and inflammatory mediators associated with chronic hyperoxia in neonatalmice显示文摘 | Warner B Stuart L Papes R | 1997 | Pediatr Res1997,41,2: | 1 |
| 13 | Quantitative analysis of over 20 years of golf course monitoring studies显示文摘 | Reuben D B Stuart Z C Barnes N L | | 0,,06: | 1 |
| 14 | Technical efficiency evaluation of logging contractors using a nonparametric model 显示文摘 | LEBEL L G STUART W B | 1998 | Inter J of Forest Engineering1998,9,2: | 1 |
| 15 | miRNA expression patterns of Triticum dicoccoides in response to shock drought stress 显示文摘 | Melda K Stuart J L Hikmet B | 2010 | Planta2010,35,12: | 1 |
| 16 | Alkylamide and cichoric acid levels in Echinacea purpurea grown in Australia 显示文摘 | Wills 1k B H Stuart D L | 1999 | Food Chemistry1999,67,4: | 1 |
| 17 | Returns to scale in the Eastern United States logging industry 显示文摘 | STUART W B GRACE L A GRALA R K | 2010 | Forest Poli- cy and Economics2010,12,6: | 1 |
| 18 | Redox regulation of manganese superoxide dismutase显示文摘 | WARNER B B STUART L GEBB S | 1996 | Am J Physiol1996,271,: | 1 |
| 19 | Effect of Drying Temperature on Alkylamide and Cichoric Acid 显示文摘 | Doug las L Stuart and Ron B H Willes | 2003 | Agric Food Chem2003,51,: | 1 |
| 20 | Carbonaceous Sedimentary Source - Rock Model for Carlin - Type and Orogenic Gold Depos- its显示文摘 | Ross R L Stuart W B Valeriy V M | 2011 | Economic Geology2011,,106: | 1 |