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| 1 | The role of chemokines in acute and chronic hepatitis C infection显示文摘丙肝在全球保健上强加重要负担。长期的感染与典型地在肝硬化,机关失败和癌症表明的肝的进步发炎被联系。由精致的避免策略的优点,丙肝病毒(HCV ) 作为一个坚持的人的病毒成功。它有一个非凡的能力破坏使它能建立长期的感染和联系的肝疾病的有免疫力的反应。Chemokines 是低分子的重量调停的趋化性的肽进纸巾的煽动性的房间和进 lymphatics 和外部血的背的招募。因此,他们对受动器和规章的有免疫力的房间的时间、空间的分发中央。在 chemokines 和他们的血缘的受体帮助之间的相互作用塑造有免疫力的反应因此,在感染的结果上有主要影响。然而, chemokines 包括 HCV 由病毒为调整代表一个目标。HCV 被知道并且可以因此由通过改变的白血球在 vivo 破坏有免疫力的反应启用它的幸存趋化性导致损害病毒的清理和长期的低档发炎的建立在 vitro 调制 chemokine 表示。在这评论,在尖锐、长期的 HCV 感染的 chemokines 的角色被描述,一个特别重音作为有免疫力的颠覆的一个工具放了在 chemokine 调整上。我们提供一在里面部分的深度讨论在调停由 chemokines 玩了肝的纤维变性当在预示的药为这些 chemoattractants 探讨潜在的应用时。 | Stephen Fahey Eugene Dempsey Aideen Long | 2014 | Cellular & Molecular Immunology2014,11,1: | 9 |
| 2 | 应收款项类投资加大中资银行系统性风险显示文摘2012年以来,中资银行的应收款项类投资,包括非金融机构设立的信托和资产管理计划、银行理财产品和债券增长迅速。此类投资的迅速增长与监管机构对银行信贷行为的严格监管有关。由于收益高、拨备成本低、资本消耗小,此类投资可以在信贷成本上升且净息差下降的环境下支持银行盈利增长,并促进银行资产多元化,但也会增加银行的信贷、流动性和利率等风险,尤其对中小银行的影响更大。银行及监管等部门有必要未雨绸缪,对此予以重视。 | 尹劲桦 刘旻雁 Stephen long | 2016 | 新金融2016,,10: | 8 |
| 3 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010,7,3: | 3 |
| 4 | Managing airport stormwater containing deicers: challenges and opportunities显示文摘在机场的 Stormwater 流量是一个重要、昂贵的问题,特别为高生物化学的氧的沾染物要求的载满除去的 stormwater (BOD ) 和水的毒性。减少装载除去在 stormwater 并且到的成分管理紧缩规定,识别命运和运输并且评估 stormwater 具有批评重要性的除去的环境风险的增加的压力。在这评论,机场除去的规章的开发 stormwater 管理首先被讨论,与里程碑机场合作研究程序(ACRP ) 一起报导 14 出版。deicer 用法和逃亡者损失能被减少,收集的 deicer 的数量能被有命运的更好的理解增加并且在 stormwater 除去搬运成分。因此,在 deicers 的担心的成分的概述和评估被提供支持对环境影响和缓解建议的评价。stormwater 管理当时是的机场除去的知识的国家考察了,它需要被综合进一个国家指导文件。当对运作的限制在环境、经济、社会的价值平衡他们的优先级时,为机场的一个旅游指南和一个决定工具被建议采用特定的实际 stormwater 管理策略。改进机场除去的当前的惯例的这些挑战姿势伟人机会 stormwater 管理。 | Xianming SHI Stephen M. QUILTY Thomas LONG Anand JAYAKARAN Laura FAY Gang XU | 2017 | Frontiers of Structural and Civil Engineering2017,11,1: | 1 |
| 5 | The accurate determination of potassium and calcium using isotope dilution inductively coupled 'cold' plasma mass spectrometry显示文摘 | Karen E Murphy Stephen E Long Michael S Rearick | 2002 | J Anal2002,17,46: | 1 |
| 6 | Optimal Tariffs on Exhaustible Resources in the Presence of Cartel Behavior 显示文摘 | Stephen Jui Hsien Chou Ngo Van Long | 2009 | Asia-Pacific Journal of Accounting & Economics 16(2009)239-2542009,16,: | 1 |
| 7 | Miscanthus for Renewable Energy Generation: European Union Experience and Projections for Illinois显示文摘 | Emily A. Heaton Stephen P. Long Thomas B. Voigt Michael B. Jones John Clifton-Brown | 2004 | Mitigation and Adaptation Strategies for Global Change2004,,4: | 1 |
| 8 | Noise Estimation in Long-Range Matched-Filter Envelope Sonar Data显示文摘 | Robert Bares Dafydd Evans Stephen Long | 2010 | JOURNAL OFOCEANIC ENGINEERING2010,,5: | 1 |
| 9 | Income Tax Effects on Donor Choice of Money and Time Contributions显示文摘 | Stephen | | National Tax Journal0,2,: | 1 |
| 10 | A Placebo-Controlled Trial of Prostacyclin in Acute Respiratory Failure in COPD显示文摘 | Stephen L. Archer Debra Mike James Crow Walker Long E. Kenneth Weir | 1996 | Chest1996,,: | 1 |
| 11 | Induction of gene expression in human pulmonary artery smooth muscle cells by bone morphogenetic proteins显示文摘 | Long L Scott L Stephens R | 2001 | Thorax2001,56,: | 1 |
| 12 | Biomechanical evaluation of lumbosacral reconstructure technique for spondylolisthesis显示文摘 | Bryan W Stephen J John Long | 2002 | Spine2002,27,: | 1 |
| 13 | Large construction projects in developing countries : a case study from Vietnam 显示文摘 | Nguyen Duy Long Stephen Ogunlana Truong Quang Ka Chi Lain | 2004 | International Journal of Project Management2004,22,: | 1 |
| 14 | Seasonal dynamics of above‐ and below‐ground biomass and nitrogen partitioning in M iscanthus ?×? giganteus and P anicum virgatum across three growing seasons显示文摘 | Frank G. Dohleman Emily A. Heaton Rebecca A. Arundale Stephen P. Long | 2012 | Glob Change Biol Bioenergy2012,,5: | 1 |
| 15 | Design of Class E Power Amplifier with Nonlinear Parasitic Output Capacitance显示文摘 | Petteri Alinikula Kevin Choi Stephen I Long | 1999 | IEEE Transactions on Circuits and System-Ⅱ:Analog and Digital Signal Processing1999,46,2: | 1 |
| 16 | Large construction projects in developing countries: a case study from Vietnam显示文摘 | Nguyen Duy Long Stephen Ogunlana Truong Quang Ka Chi Lam | 2004 | International Journal of Project Management2004,,55: | 1 |
| 17 | Urinary iodine and stable isotope analysis to examine habitat influences on thyroid hormones among coastal dwelling American alligators显示文摘 | Ashley S.P. Boggs Heather J. Hamlin James C. Nifong Brittany L. Kassim Russell H. Lowers Thomas M. Galligan Stephen E. Long Louis J. Guillette | 2016 | General and Comparative Endocrinology2016,,: | 1 |
| 18 | Docosahexaenoic Acid and Amino Acid Contents in Pasteurized Donor Milk are Low for Preterm Infants显示文摘 | Christina J. Valentine Georgia Morrow Soledad Fernandez Parul Gulati Dennis Bartholomew Don Long Stephen E. Welty Ardythe L. Morrow Lynette K. Rogers | 2010 | The Journal of Pediatrics2010,,6: | 1 |
| 19 | Laparoscopic nephrectomy显示文摘 | Ralph V. Clayman Louis R. Kavoussi Nathaniel J. Soper Stephen M. Dierks Shimon Meretyk Michael D. Darcy Stephanie R. Long | 2002 | The Journal of Urology2002,,2: | 1 |
| 20 | Cardiovascular Disease in Pregnancy: (Women’s Health Series)显示文摘 | Myrna Alexander Nickens Robert Craig Long Stephen A. Geraci | 2013 | Southern Medical Journal2013,,11: | 1 |