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| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013，16，7： | 70 |
| 2 | MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration显示文摘 | Arora S Ranade AR Tran NL Nasser S Sridhar S Korn RL Ross JT Dhruv H Foss KM Sibenaller Z Ryken T Gotway MB Kim S Weiss GJ | 2011 | 中国神经肿瘤杂志2011，9，1： | 30 |
| 3 | Eosinophilic ascites,an unusual presentation of eosinophilic gastroenteritis:A case report and review显示文摘Eosinophilic ascites(EA)is a rare disorder of unknown etiology that has been reported in both adult and pediatric patients.It is a part of the syndrome of eosinophilic gastroenteritis,which is characterized by eosinophilic infiltration of any or all layers of the gut wall and may involve any segment of the gastrointestinal tract.Peripheral eosinophilia may or may not be present.We report a case of EA that developed post partum. | Iryna S Hepburn Subbaramiah Sridhar Robert R Schade | 2010 | World Journal of Gastrointestinal Pathophysiology2010，1，5： | 22 |
| 4 | Genetic epidemiology of irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS) is the most common functional gastrointestinal disorder characterized by presence of abdominal pain or discomfort associated with altered bowel habits. It has three main subtypes- constipation predominant IBS(C-IBS),diarrhea predominant IBS(D-IBS) and IBS with mixed featuresof both diarrhea as well as constipation(M-IBS). Its pathophysiology and underlying mechanisms remain elusive. It is traditionally believed that IBS is a result of multiple factors including hypersensitivity of the bowel,altered bowel motility,inflammation and stress. Initial studies have shown familial aggregation of IBS suggesting shared genetic or environmental factors. Twin studies of IBS from different parts of world have shown higher concordance rates among monozygotic twins than dizygotic twins,and thus suggesting a genetic component to this disorder. Multiple studies have tried to link single-nucleotide polymorphisms(SNPs) to IBS but there is little evidence that these SNPs are functional. Various molecules have been studied and investigated by the researchers. Serotonin,a known neurotransmitter and a local hormone in the enteric nervous system,has been most extensively explored. At this time,the underlying gene pathways,genes and functional variants linked with IBS remain unknown and the promise of genetically-determined risk prediction and personalize medicine remain unfulfilled. However,molecular biological technologies continue to evolve rapidly and genetic investigations offer much promise in the intervention,treatment and prevention of IBS. | Jasbir Makker Sridhar Chilimuri Jonathan N Bella | 2015 | World Journal of Gastroenterology2015，21，40： | 20 |
| 5 | 基于多特征融合的SVM声学场景分类算法研究显示文摘针对DCASE2017挑战赛的声场环境数据集,提取梅尔频率倒谱系数(MFCC)、短时能量(SE)、声学事件似然特征(AELF)、静音时间(MT)特征,组成多特征融合矩阵,通过对比多种核函数和寻优算法,最终选取高斯径向基核函数(RK)建立支持向量机(SVM)模型,采用交叉验证(CV)方法进行SVM参数寻优,对15种声学场景进行分类.实验结果表明,杂货店、办公室的分类准确性达到了90%以上,平均分类准确性达到71.11%,远高于挑战赛的基线系统61%的平均分类准确性. | 赵薇 靳聪 涂中文 SRIDHAR Krishnan 刘杉 | 2020 | 北京理工大学学报2020，40，1： | 13 |
| 6 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 7 | Emerging links between type 2 diabetes and Alzheimer's disease显示文摘Type 2 diabetes mellitus and Alzheimer's disease are both associated with increasing age,and each increases the risk of development of the other.Epidemiological,clinical,biochemical and imaging studies have shown that elevated glucose levels and diabetes are associated with cognitive dysfunction,the most prevalent cause of which is Alzheimer's disease.Cross sectional studies have clearly shown such an association,whereas longitudinal studies are equivocal,reflecting the many complex ways in which the two interact.Despite the dichotomy,common risk and etiological factors(obesity,dyslipidemia,insulin resistance,and sedentary habits) are recognized;correction of these by lifestyle changes and pharmacological agents can be expected to prevent or retard the progression of both diseases.Common pathogenic factors in both conditions span a broad sweep including chronic hyperglycemia per se,hyperinsulinemia,insulin resistance,acute hypoglycemic episodes,especially in the elderly,microvascular disease,fibrillar deposits(in brain in Alzheimer's disease and in pancreas in type 2 diabetes),altered insulin processing,inflammation,obesity,dyslipidemia,altered levels of insulin like growth factor and occurrence of variant forms of the protein butyrylcholinesterase.Of interest not only do lifestyle measures have a protective effect against the development of cognitive impairment due to Alzheimer's disease,but so do some of the pharmacological agents used in the treatment of diabetes such as insulin(especially when delivered intranasally),metformin,peroxisome proliferator-activated receptors γ agonists,glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors.Diabetes must be recognized as a risk for development of Alzheimer's disease;clinicians must ensure preventive care be given to control and postpone both conditions,and to identify cognitive impairment early to manage it appropriately. | Gumpeny R Sridhar Gumpeny Lakshmi Gumpeny Nagamani | 2015 | World Journal of Diabetes2015，6，5： | 10 |
| 8 | 共享服务在中国渐行其道显示文摘随着市场的日益成熟。竞争促使各家公司采用更为有效和更具持续性的共享服务战略,但要成功实施这一做法,需要细致的规划、高层管理者的支持以及整个组织的转型。 | Nick Rossiter Sridhar Vedala | 2006 | IT时代周刊2006，，13： | 9 |
| 9 | 弹靶尺寸对陶瓷/金属复合装甲防护性能的影响显示文摘利用Autodyn软件开展数值模拟工作,对陶瓷/金属复合装甲的防护性能与弹靶尺寸的关系进行研究。首先,建立二维轴对称SPH-Lagrange模型,并利用实验数据验证模型有效性;在此基础上对不同几何参数的弹靶撞击进行数值模拟,分析靶板厚度、靶板平面尺寸、子弹长度等对氧化铝陶瓷/铝合金复合装甲弹道极限速度的影响规律。然后,通过量纲分析,提出装甲弹道极限速度与弹靶几何参数的量纲一关系式,并在数值模拟结果的基础上建立一个装甲弹道极限速度的经验公式。 | 迟润强 Ahmad Serjouei 范峰 Idapalapati Sridhar | 2014 | 爆炸与冲击2014，34，5： | 6 |
| 10 | Petrological Characteristics and Genesis of the Central Indian Ocean Basin Basalts显示文摘The Central Indian Ocean Basin (CIOB) basalts are plagioclase-rich, while olivine and pyroxene are very few. The analyses of 41 samples reveal high FeOT (~10-18 wt%) and TiO 2 (~1.4-2.7 wt%) indicating a ferrobasaltic composition. The basalts have high incompatible elements (Zr 63-228 ppm; Nb ~1-5 ppm; Ba ~15-78 ppm; La ~3-16 ppm), a similar U/Pb (0.02-0.4) ratio as the normal mid -oceanic basalt (0.16±0.07) but the Ba/Nb (12.5-53) ratio is much larger than that of the normal midoceanic ridge basalt (~5.7) and Primitive Mantle (9.56). Interestingly almost all of the basalts have a significant negative Eu anomaly (Eu/Eu*=0.78-1.00) that may have been a result of the removal of feldspar and pyroxene during crystal fractionation. These compositional variations suggest that the basalts were derived through fractional crystallization together with low partial melting of a shallow seated magma. | Pranab DAS Sridhar D.IYER Sugata HAZRA | 2012 | Acta Geologica Sinica(English Edition)2012，86，5： | 6 |
| 11 | What every gastroenterologist needs to know about common anorectal disorders显示文摘Anorectal complaints are very common and are caused by a variety of mostly benign anorectal disorders.Many anorectal conditions may be successfully treated by primary care physicians in the outpatient setting,but patients tend not to seek medical attention due to embarrassment or fear of cancer.As a result,patients frequently present with advanced disease after experiencing significant decreases in quality of life.A number of patients with anorectal complaints are referred to gastroenterologists.However,gastroenterologists' knowledge and experience in approaching these conditions may not be sufficient.This article can serve as a guide to gastroenterologists to recognize,evaluate,and manage medically or non-surgically common benign anorectal disorders,and to identify when surgical referrals are most prudent.A review of the current literature is performed to evaluate comprehensive clinical pearls and management guidelines for each topic.Topics reviewed include hemorrhoids,anal fissures,anorectal fistulas and abscesses,and pruritus ani. | Moonkyung Cho Schubert Subbaramiah Sridhar Robert R Schade Steven D Wexner | 2009 | World Journal of Gastroenterology2009，15，26： | 5 |
| 12 | Effect of dietary incorporation of n-3 polyunsaturated fatty acids rich oil sources on fatty acid profile, keeping quality and sensory attributes of broiler chicken meat显示文摘The present study was undertaken to investigate the effect of dietary replacement of commonly used vegetable oil(sunflower oil, SFO) with n-3 polyunsaturated fatty acids(PUFA) rich oil sources on broiler chicken performance, carcass yield, meat fatty acid composition, keeping quality and sensory attributes of meat. In the current experiment, 300 day-old Krishibro broiler chicks were randomly distributed to 5 dietary groups(50 replicates with 6 chicks in each) prepared by replacing SFO(2% and 3% of diet during starter and finisher periods, respectively) with n-3 PUFA rich soybean oil(SO), mustard oil(MO), linseed oil(LO) or fish oil(FO) on weight basis. Variation in oil sources had no influence(P > 0.05) on performance and carcass yield. Supplementation of MO, LO or FO significantly(P < 0.01) increased the n-3 PUFA, lowered the n-6 PUFA deposition and n-6:n-3 ratio in breast and thigh without affecting the organoleptic characters(appearance, flavour, juiciness, tenderness and overall acceptability) of meat.However, thiobarbituric acid reacting substances concentration in meat was increased(P < 0.01) with LO and FO supplementation compared with SFO. It is concluded that, dietary incorporation of MO, LO or FO at 2% and 3% levels during starter and finisher phase can enrich broiler chicken meat with n-3 PUFA without affecting the bird's performance and sensory characters of meat. | Sridhar Kalakuntla Nalini K.Nagireddy Arun K.Panda Narasimha Jatoth Raghunandan Thirunahari Ravinder R.Vangoor | 2017 | Animal Nutrition2017，，4： | 5 |
| 13 | Characterization of Microstructure, Strength, and Toughness of Dissimilar Weldments of Inconel 625 and Duplex Stainless Steel SAF 2205显示文摘The dissimilar combinations of Inconel 625 and duplex stainless steel SAF 2205 obtained from manual GTA welding process employing ER2209 and ERNi CrMo-3 filler metals have been investigated. Formation of secondary phases at the HAZ of Inconel 625 and grain coarsening at the HAZ of SAF 2205 were witnessed while using these filler wires. The average hardness of ER2209 weldments was found to be greater than ERNi CrMo-3 weld. Tensile fracture was observed at the weld zones for both the fillers. Impact test trials showed brittle mode of fracture on employing ER2209 filler and mixed(ductile–brittle) mode of fracture while using ERNi CrMo-3 filler. Further optical microscopy and SEM/EDS analysis were carried out across the weldments to investigate the structure–property relationships. | R. Sridhar K. Devendranath Ramkumar N. Arivazhagan | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，6： | 5 |
| 14 | Impact of poly chlorinated biphenyl (Aroclor 1254) and vitamin C on antioxidant system of rat ventral prostate显示文摘Aim:To evaluate the effect of polychlorinated biphenyls (PCB) and vitamin C on ventral prostatic antioxidant system in adult male rats.Methods:A group of 20 adult male rats were administered ip Aroclor 1254 in corn oil at a dose of 2 mg.kg^-1·day^-1 for 30 days.Ten control rats were administered only the vehicle.After 30 days the treated rats were divided at random into 2 sub-groups of 10 animals each.One sub-group received vitamin C at a dose of 500 mg.kg^-1·day^-1 for 10 days.The other group was maintained as Aroclor 1254 control.Twenty-four hours after the last treatment the rats were killed by decapitation.Ventral prostatic homogenate was prepared and used for the estimation of enzymatic antioxidants,including superoxide dismutase (SOD),catalase (CAT) and glutathione-S-transferase (GST) and hydrogen peroxide (H2O2),lipid peroxidation (LPO) and prostatic acid phosphatase.The serum levels of total T3,total T4,TSH,testosterone and estradiol were also assayed.Results:The body weight and ventral prostatic weight were reduced in PCB treated rats.The activities of SOD,CAT,GST and acid phosphatase were decreased while the levels of H2O2 and lipid peroxidation were increased in the ventral prostate of PCB treated rats.Administration of vitamin C restored these parameters.Serum levels of thyroid hormones,estradiol and testosteron ewere decreased in PCB treated animals.Administration of vitamin C restored the thyroid hormone levels.Conclusion:PCB induces oxidative stress and decreases the antioxidant enzymes in the ventral prostate of adult male rats;the effects could be reversed by the administration of vitamin C.(Asian J Androl 2004 Mar;6:19-22) | M. Sridhar P. Venkataraman S. Dhanammal A. Arunkumar M.M. Aruldhas N. Srinivasan J. Arunakaran | 2004 | Asian Journal of Andrology2004，6，1： | 5 |
| 15 | Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality显示文摘AIM: To assess the additive effect of lubiprostone on the quality of colon preparation in diabetics given single-dosed polyethylene glycol electrolyte(PEG)for colonoscopy.METHODS:This was an investigator-initiated,singlecenter,single-blinded prospective trial comparing the efficacy of L+PEG to PEG alone on colon preparation quality in diabetics undergoing screening colonoscopy.The study was approved by our institution’s IRB.The PEG was given as a single-dose to address patientcompliance concerns voiced by our IRB with splitdosing.All patients received only clear liquids the day prior to colonoscopy.Experimental group(Grp L)received PEG+1 dose L 2 h prior to and 2 h after PEG completion.Control group(Grp C)received only PEG the evening prior to the colonoscopy.Patients were randomly assigned to one of the 2 groups.The endoscopist was blinded to which colon prep was given and all colonoscopies were complete.Upon colonoscopy completion,the endoscopist rated the colon prep-quality by a validated 5-point Likert scale(1-excellent to 5-inadequate).RESULTS:Sixty patients were enrolled in the study;30 Grp L and 30 Grp C.Overall,patients were excluded due to study non-completion in 12(41%)Grp L and 5(17%) Grp C,P=0.04.Average colon preparation score Grp L =2.47 and Grp C=3.00,P=0.09.Although this was not statistically significant,there was a trend towards improved colon prep in Grp L.Statistical significance may have been achieved if completion rates had been similar between both study groups.CONCLUSION:Use of 2-L capsules with PEG resulted in a trend towards improved colon prep over PEG alone in diabetic patients when given as a single-dose regimen. | Erika Grigg Moonkyung C Schubert Joshua Hall Fadi Rahhal Dimple Raina Subbaramiah Sridhar Sherman M Chamberlain | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，7： | 5 |
| 16 | Nerve-sparing robot-assisted radical prostatectomy:Current perspectives显示文摘Robotic-assisted radical prostatectomy(RARP)is the current standard of care with long term cure in organ-confined disease.The introduction of nerve-sparing(NS)to standard RARP has shown positive results in terms of functional outcomes in addition to the oncological outcomes.This article reviews the current perspectives of NS-RARP in terms of applied anatomy of the prostatic fascial planes,the neurovascular bundle(NVB),various NS techniques and postoperative functional outcomes.A non-systematic review was done using PubMed,Embase and Medline databases to retrieve and analyse articles in English,with following keywords“prostate cancer”,“robotic radical prostatectomy”,“nerve-sparing”.The Delphi method was used with an expert panel of robotic surgeons in urology to analyse the potency outcomes of various published comparative and non-comparative studies.The literature has shown that NS-RARP involves various techniques and approaches while there is a lack of randomized studies to suggest the superiority of one over the other.Variables such as preoperative risk assessments,baseline potency,surgical anatomy of individual patients and surgeons’expertise play a major role in the outcomes.A tailored approach for each patient is required for applying the NS approach during RARP. | Anup Kumar Vipul RPatel Sridhar Panaiyadiyan Kulthe Ramesh Seetharam Bhat Marcio Covas Moschovas Brusabhanu Nayak | 2021 | Asian Journal of Urology2021，8，1： | 4 |
| 17 | Equivalent protection factor of bi-layer ceramic metal structures显示文摘With increasing ballistic threat levels,there is ever more demand on developing ceramic armor designs with improved performance.This paper presents finite element simulations that investigate the performance of silicon carbide ceramic with steel 4340 backing material and titanium alloy,graphite as buffer layers when subjected to normal and oblique impacts by a tungsten alloy long rod projectile(LRP).Depth of penetration from experimental measurements is compared with simulations to confirm the validity of constitutive,failure model parameters.Titanium alloy cover plate and graphite interface weak layer laterally spread the impact shock away from the SiC tile and reduces the amplification of the stress accumulation at the front surface of the SiC tile.The dwelling time increases before it penetrates into ceramic armor.Further,using AUTODYN®numerical simulations detailed parametric study is carried out to identify the minimum areal density armor for a given ballistic limit velocity.The equivalent protection factor for the bi-layer armor is a simple function of the cosine of the angle of impact. | Govind Gour Sridhar Idapalapati Wei Liang Goh Xiao-peng Shi | 2022 | Defence Technology(防务技术)2022，18，3： | 4 |
| 18 | Evidences for Incipient Hydrothermal Event(s) in the Central Indian Basin: A Review显示文摘The Central Indian Basin (CIB, 10°-19°S) encompasses morphotectonic features such as seamounts, abyssal hills, faults, fracture zones and lineations and basic to silicic volcanics that were derived from different sources. Instances of incipient hydrothermal event (s) occurred as evident from: (1) spilites that probably formed due to low-temperature hydrothermal action on the precursory basalts, (2) slabs and fragments of zeolitites which are the consequent products of palagonitization of the basaltic glasses, (3) chemical variations in the ferromanganese crusts, and (4) abundance of volcanogenic-hydrothermal material (vhm) that includes ochrous sediments and magnetite spherules. The vhm suggests its origin by interaction of Fe-rich hydrothermal solutions with surrounding sediments. The CIB spherules occur in sediments of^10 ka and ~425 to 650 ka age and are orders of magnitude younger than the 50 to 60 Ma age of the basin. Incidentally, to the north of the basin at ODP Site 717-719(1 °S/81 °E) hydrothermal precipitates of inorganic calcite and deposition of sulphide minerals (~7.5 to 9 Ma and 0.5 Ma) occur as a result of the on-going intraplate deformation. This paper reviews the above evidences that possibly indicate episodes of localized hydrothermal events in the CIB. | Sridhar D. IYER | 2005 | Acta Geologica Sinica(English Edition)2005，79，1： | 4 |
| 19 | Codon bias and heterologous protein expression显示文摘 | Claes Gustafsson Sridhar Govindarajan Jeremy Minshull | 2004 | Trends in Biotechnology2004，，7： | 4 |
| 20 | Distribution of Pill Millipedes (Arthrosphaera) and Associated Soil Fauna in the Western Ghats and West Coast of India显示文摘Seven sampling sites in each of three biomes (Western Ghats, foothills of Western Ghats and west coast) of south- western India were investigated to study the distribution, abundance and ecology of pill millipedes (Arthrosphaera) and associated fauna in relation to edaphic features. Abundance and biomass of Arthrosphaera and other millipedes were the highest in Western Ghats, while earthworms were in foothills. Arthrosphaera magna and Arthrosphaera spp. were common in Western Ghats and foothills respectively, while no Arthrosphaera were found in the west coast. None of the sampling sites consisted of more than one species of Arthrosphaera. Biomass of Arthrosphaera, other millipedes and earthworms significantly differed in Western Ghats (P = 9.48 × 10-7) and foothills (P = 1.35 × 10-8), as did the biomass of species of Arthrosphaera (P = 2.76 × 10-7) between Western Ghats and foothills. Correlation analysis revealed that biomass of Arthrosphaera was significantly (P = 0.01, r = 0.45) correlated with soil organic carbon rather than other edaphic fea- tures (pH, phosphate, calcium and magnesium). Distribution pattern, abundance, biomass and ecology of Arthrosphaera of Western Ghats in relation to soil qualities were compared with millipedes of other regions of the world. | K. M. ASHWINI K. R. SRIDHAR | 2008 | Pedosphere2008，18，6： | 4 |
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