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| 1 | 从白屈菜乙醇提取物中分离出的白屈菜碱通过p38-p53和PI3K/AKT信号转导通路促进 HeLa细胞凋亡(英文)显示文摘目的:研究从白屈菜乙醇提取物中分离出的白屈菜碱在诱导 HeLa细胞凋亡中的作用及参与其作用的主要信号转导通路。方法:细胞先以不同浓度白屈菜碱处理48h,用噻唑蓝法分析确定半数致死量(median lethal dose,LD50)。用4′,6-二脒基-2-苯基吲哚染色,追踪分析核浓染以及 DNA 损伤和碎片的形态学变化,并用流式细胞术分析检测活性氧(reactive oxygen species,ROS)的产生以及细胞周期阻滞和线粒体膜电位的变化。用圆二色光谱分析寻找白屈菜碱和小牛胸腺 DNA可能的相互作用。用逆转录聚合酶链反应和蛋白免疫印迹法测定p38、p53、蛋白激酶B(protein kinase B,AKT)、磷脂酰肌醇3-激酶(phosphatidylinositol 3-kinases,PI3K)、Janus激酶3(Janus kinase 3,JAK3)、信号转导及转录激活因子3(signal transducer and activator oftranscription 3,STAT3)等的mRNA和蛋白表达,以及E6、E7癌基因和促凋亡基因、抗凋亡基因的mRNA和蛋白表达。结果:根据白屈菜碱的LD50(30μg/mL),选定3种实验剂量,即22.5、30和37.5μg/mL。结果显示,白屈菜碱抑制了 HeLa细胞增殖,诱发其细胞凋亡,表现为 ROS的产生,细胞亚 G1和 G0/G1周期阻滞,线粒体膜电位变化和 DNA 碎片产生。圆二色光谱分析结果显示白屈菜碱和小牛胸腺 DNA 间存在有效的相互作用。信号通路的研究显示白屈菜碱通过上调p38、p53和其他促凋亡基因的表达,以及下调 AKT、PI3K、JAK3、STAT3、E6、E7和其他抗凋亡基因的表达,有效诱发细胞凋亡。结论:从白屈菜中分离出的白屈菜碱能通过改变p38-p53及 AKT/PI3激酶信号转导通路有效地诱发 HeLa细胞凋亡。 | Avijit Paul Kausik Bishayee Samrat Ghosh Avinaba Mukherjee Sourav Sikdar Debrup Chakraborty Naoual Boujedaini Anisur Rahman Khuda-Bukhsh | 2012 | 中西医结合学报2012,10,9: | 10 |
| 2 | Light signaling and UV-B-mediated plant growth regulation^FA显示文摘Light plays an important role in plants' growth and development throughout their life cycle. Plants alter their morphological features in response to light cues of varying intensity and quality. Dedicated photoreceptors help plants to perceive light signals of different wave-lengths. Activated photoreceptors stimulate the down-stream signaling cascades that lead to extensive gene expression changes responsible for physiological and developmental responses. Proteins such as ELONGATED HYPOCOTYL5 (HY5) and CONSTITUTIVELY PHOTO-MORPHOGENIC 1 (COP1) act as important factors which modulate light-regulated gene expression, especially during seedling development. These factors function as central regulatory intermediates not only in red, far-red, and blue light pathways but also in the UV-B signaling pathway. UV-B radiation makes up only a minor fraction of sunlight, yet it imparts many positive and negative effects on plant growth. Studies on UV-B perception, signaling, and response in plants has considerably surged in recent times. Plants have developed different strat-egies to use UV-B as a developmental cue as well as to withstand high doses of UV-B radiation. Plants' re-sponses to UV-B are an integration of its cross-talks with both environmental factors and phytohormones. This review outlines the current developments in light sig-naling with a major focus on UV-B-mediated plant growth regulation. | Arpita Yadav Deeksha Singh Maneesh Lingwan Premachandran Yadukrishnan Shyam Kumar Masakapalli Sourav Datta | 2020 | Journal of Integrative Plant Biology2020,62,9: | 6 |
| 3 | Properties of boron doped ZnO films prepared by reactive sputtering method: Application to amorphous silicon thin film solar cells显示文摘Reactive sputtered boron-doped zinc oxide(BZO) film was deposited from argon,hydrogen and boron gas mixture.The reactive sputtering technique provides us the flexibility of changing the boron concentration in the produced films by using the same intrinsic zinc oxide target.Textured surface was obtained in the as-deposited films.The surface morphology and the opto-electronic properties of the films can be controlled by simply varying the gas concentration ratio.By varying the gas concentration ratio,the best obtained resistivity ~6.51×10^-4Ω-cm,mobility ~19.05 cm^2 V^-1 s^-1 and sheet resistance ~7.23Ω/□ were obtained.At lower wavelength of light,the response of the deposited films improves with the increase of boron in the gas mixture and the overall transmission in the wavelength region 350-1100 nm of all the films are>85 %.We also fabricated amorphous silicon(a-Si) thin film solar cell on the best obtained BZO layers.The overall efficiency of the a-Si solar cell is 8.14 %,found on optimized BZO layer. | Sukanta Bose Sourav Mandal Asok K.Barua Sumita Mukhopadhyay | 2020 | Journal of Materials Science & Technology2020,52,20: | 6 |
| 4 | A theory of entrepreneurial opportunity identification and development显示文摘 | Alexander Ardichvili Richard Cardozo Sourav Ray | 2003 | Journal of Business Venturing2003,,1: | 5 |
| 5 | Homeopathic mother tincture of Phytolacca decandra induces apoptosis in skin melanoma cells by activating caspase-mediated signaling via reactive oxygen species elevation显示文摘OBJECTIVE: Preventive measures against skin melanoma like chemotherapy are useful but suffer from chronic side effects and drug resistance. Ethanolic extract of Phytolacca decandra (PD), used in homeopathy for the treatment of various ailments like chronic rheumatism, regular conjunctivitis, psoriasis, and in some skin diseases was tested for its possible anticancer potential. METHODS: Cytotoxicity of the drug was tested by conducting 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on both normal (peripheral blood mononuclear cells) and A375 cells. Fluorescence microscopic study of 4',6-diamidino-2-phenylindole dihydrochloride-stained cells was conducted for DNA fragmentation assay, and changes in cellular morphology, if any, were also recorded. Lactate dehydrogenase activity assay was done to evaluate the percentages of apoptosis and necrosis. Reactive oxygen species (ROS) accumulation, if any, and expression study of apoptotic genes also were evaluated to pin-point the actual events of apoptosis. RESULTS: Results showed that PD administration caused a remarkable reduction in proliferation of A375 cells, without showing much cytotoxicity on peripheral blood mononuclear cells. Generation of ROS and DNA damage, which made the cancer cells prone to apoptosis, were found to be enhanced in PD-treated cells. These results were duly supported by the analytical data on expression of different cellular and nuclear proteins, as for example, by down-regulation of Akt and Bcl-2, up-regulation of p53, Bax and caspase 3, and an increase in number of cell deaths by apoptosis in A375 cells. CONCLUSION: Overall results demonstrate anticancer potentials of PD on A375 cells through activation of caspase-mediated signaling and ROS generation. | Samrat Ghosh Kausik Bishayee Avijit Paul Avinaba Mukherjee Sourav Sikdar Debrup Chakraborty Naoual Boujedaini Anisur Rahman Khuda-Bukhsh | 2013 | Journal of Integrative Medicine2013,11,2: | 5 |
| 6 | Design of a Proportional-Integral-Derivative Controller for an Automatic Generation Control of Multi-area Power Thermal Systems Using Firefly Algorithm显示文摘Essentially, it is significant to supply the consumer with reliable and sufficient power. Since, power quality is measured by the consistency in frequency and power flow between control areas. Thus, in a power system operation and control,automatic generation control(AGC) plays a crucial role. In this paper, multi-area(Five areas: area 1, area 2, area 3, area 4 and area 5) reheat thermal power systems are considered with proportional-integral-derivative(PID) controller as a supplementary controller. Each area in the investigated power system is equipped with appropriate governor unit, turbine with reheater unit, generator and speed regulator unit. The PID controller parameters are optimized by considering nature bio-inspired firefly algorithm(FFA). The experimental results demonstrated the comparison of the proposed system performance(FFA-PID)with optimized PID controller based genetic algorithm(GAPID) and particle swarm optimization(PSO) technique(PSOPID) for the same investigated power system. The results proved the efficiency of employing the integral time absolute error(ITAE) cost function with one percent step load perturbation(1 % SLP) in area 1. The proposed system based FFA achieved the least settling time compared to using the GA or the PSO algorithms, while, it attained good results with respect to the peak overshoot/undershoot. In addition, the FFA performance is improved with the increased number of iterations which outperformed the other optimization algorithms based controller. | K.Jagatheesan B.Anand Sourav Samanta Nilanjan Dey Amira S.Ashour Valentina E.Balas | 2019 | IEEE/CAA Journal of Automatica Sinica2019,6,2: | 4 |
| 7 | Nitric oxide mediated Staphylococcus aureus pathogenesis and protective role of nanoconjugated vancomycin显示文摘Objective:To investigate the relation between fruit seeds,plants residuals and appendicitis. Methods:Among cases that underwent appendectomy,the appendicitis cases having fruit seeds and undigested plant residuals in their etiology were examined retrospectively.Also, histopathological features,age,sex,and parameters of morbidity and mortality were used. Results:Fruit seed was found in one case(0.05%) with presence of pus in appendix lumen, undigested plant residuals in 7 cases(0.35%).It was determined that there were appendix inflammation in 2 of the plant residuals cases,while there were obstruction and lymphoid hyperplasia in the appendix lumen of 5 cases.No mortality was observed.Conclusions:The ratio of acute appendicitis caused by plants is minimal among all appendectomised patients, but avoidence of eating undigested fruit seeds and chewing plants well may help to prevent appendicitis. | Subhankari Prasad Chakraborty Santanu Kar Mahapatra Sumanta Kumar Sahu Sourav Chattopadhyay Panchanan Pramanik Somenath Roy | 2011 | Asian Pacific Journal of Tropical Biomedicine2011,1,2: | 4 |
| 8 | In vitro and in silico studies on fibrinolytic activity of nattokinase: A clot buster from Bacillus sp.显示文摘Nattokinase (NK ) 是 subtilisin 家庭的丝氨酸朊酶酶。它展出一项强壮的 fibrinolytic 活动。从杆菌 sp 的 fibrinolytic 酶。因为他们的效率,包括胞质素激活在 fibrinolytic 过程作为 thrombolytic 代理人吸引了兴趣。在礼品的方法学习, VIT 花园土壤对隔离过程镇定、使 NK 生产遭到以便为屏蔽。为 NK 酶屏蔽被光线的 caseinolytic 试金执行。NK 酶的生产在比较研究的二不同生产媒介被做。NK 酶被胶化浸透层析净化。净化的 NK 的活动被块细胞溶解和酷蛋白消化试金检查。为了调查 NK 和纤维蛋白原相互作用并且也的结构的基础识别,最好的有约束力的模式,分子的动力学和停靠研究被执行。基于词法、生物化学的描述的结果, isolate 作为杆菌 sp 被识别。NK 的全面纯化褶层与 664U/mg 的特定的活动是大约 3, 9.9% 让步。净化的酶的同质被在 SDS 页获得的单身的乐队分析并且证实。净化的朊酶的分子的重量作为 25 kDa 被估计。净化的 NK 酶展出了 97% 有效的块细胞溶解活动。NK 被停靠在到在它用船坞服务者的有约束力的地点的纤维蛋白原的旋钮区域。纤维蛋白原的 26 残余和 NK 的 29 残余的一个总数组成接口区域。然而,纤维蛋白原(THR238, MET264, LYS266, ARG275, THR277, ALA279, ASN308, MET310,和 LYS321 ) 的 9 残余和 NK (GLY61 SER63 THR99, PHE189, LEU209, TYR217, ASN218,和 MET222 ) 的 8 残余涉及未经触动的绑定NK 酶的重要数量从杆菌 sp 被获得的结论。停靠分析表明 NK 和纤维蛋白原采用一个扩大有约束力的模式并且与关键残余交往展出他们的活动。 | V. Mohanasrinivasan. A. Mohanapriya Swaroop Potdar Sourav Chatterji Srinath Konne Sweta Kumari S. Merlyn Keziah. C. Subathra Devi | 2017 | Frontiers in Biology2017,12,3: | 4 |
| 9 | Effect of pioglitazone on nerve conduction velocity of the median nerve in the carpal tunnel in type 2 diabetes patients显示文摘AIM To evaluate the impact of pioglitazone pharmacotherapy in median nerve electrophysiology in the carpal tunnel among type 2 diabetes patients.METHODS The study was executed in patients with type 2 diabetes, treated with oral drugs, categorized under pioglitazone or non-pioglitazone group(14 in each group), and who received electrophysiological evaluation by nerve conduction velocity at baseline and 3 mo.RESULTS At 3 mo, pioglitazone-category had inferior amplitude in sensory median nerve [8.5 interquartile range(IQR) = 6.5 to 11.5) vs non-pioglitazone 14.5(IQR 10.5 to 18.75)](P = 0.002). Non-pioglitazone category displayed amelioration in amplitude in the sensory median nerve [baseline 13(IQR = 9 to 16.25) vs 3 mo 8.5(IQR = 6.5 to 11.5)](P = 0.01) and amplitude in motor median nerve [baseline 9(IQR = 4.75 to 11) vs 3 mo 6.75(IQR = 4.75 to 10.25)](P = 0.049); and deterioration of terminal latency of in motor ulnar nerve [baseline 2.07(IQR = 1.92 to 2.25) vs 3 mo 2.16(IQR = 1.97 to 2.325)](P = 0.043). There was amelioration of terminal latency in sensory ulnar nerve [baseline 2.45(IQR = 2.315 to 2.88) vs 3 mo 2.37(IQR = 2.275 to 2.445) for pioglitazone group(P = 0.038).CONCLUSION Treatment with pioglitazone accentuates probability of compressive neuropathy. In spite of comparable glycemic control over 3 mo, patients treated with pioglitazone showed superior electrophysiological parameters for the ulnar nerve. Pioglitazone has favourable outcome in nerve electrophysiology which was repealed when the nerve was subjected to compressive neuropathy. | Sudip Chatterjee Debmalya Sanyal Sourav Das Choudhury Mili Bandyopadhyay Suraj Chakraborty Arabinda Mukherjee | 2016 | World Journal of Diabetes2016,7,19: | 3 |
| 10 | 北美香柏叶的乙醇提取物阻断A549细胞增殖并引起细胞凋亡的体外研究(英文)显示文摘目的:研究北美香柏叶的乙醇提取物对非小细胞肺癌A549细胞的抗肿瘤及抗增殖作用。方法:噻唑蓝法检验不同剂量北美香柏叶的乙醇提取物对细胞活性的影响。确定半数最大抑制浓度为282μg/mL,另外选择两个浓度188μg/mL和376μg/mL进行剂量依赖性检测。进行溴脱氧尿苷结合实验和细胞迁移实验检测药物的抗肿瘤细胞增殖活性。膜联蛋白V-异硫氰酸荧光黄-碘化丙啶双染色后采用荧光激活细胞分类分析仪对细胞早期凋亡进行检测。Hoechst 33258及吖啶橙-溴化乙啶荧光染色法进行DNA片段分析。间接酶联免疫吸附法分析Bax-Bcl2的调节和表达情况。逆转录聚合酶链反应检测caspase3基因表达情况,其活性和蛋白水平的表达则使用间接酶联免疫吸附法和蛋白印迹法进行检测。结果:A549的细胞活性在暴露于北美香柏叶的乙醇提取物24h后呈剂量依赖性下降。脱氧尿苷结合实验和细胞迁移实验表明细胞的增殖活性与暴露于药物的时间有时间依赖性关系。11.72%的细胞在双染色后呈阳性反应,表明药物引起了细胞的早期凋亡。药物作用24h后DNA片段彗星尾的出现以及Hoechst 33258荧光染色的增加提示显著的DNA缺口出现以及染色质凝聚。Bax的上调及Bcl2的下调表明了细胞凋亡的出现。逆转录聚合酶链反应、间接酶联免疫吸附法以及蛋白印迹法的检测结果表明caspase3的活性随着抗聚(腺苷二磷酸-核糖)聚合酶的表达的增加而增加。结论:北美香柏叶的乙醇提取物能够促进A549细胞凋亡并抑制其增殖活性。 | Avinaba Mukherjee Sourav Sikdar Kausik Bishayee Avijit Paul Samrat Ghosh Naoual Boujedaini Anisur Rahman Khuda-Bukhsh | 2012 | 中西医结合学报2012,10,12: | 2 |
| 11 | A crystal plasticity based approach to establish role of grain size and crystallographic texture in the Tension–Compression yield asymmetry and strain hardening behavior of a Magnesium–Silver–Rare Earth alloy显示文摘Existence of tension–compression yield asymmetry is a serious limitation to the load bearing capablities of Magnesium alloys in a number of light weight structural applications.The present work is aimed at nullifying the tension to compression asymmetry problem and strain hardening anomalies in a Magnesium–Silver–Rare Earth alloy by engineering different levels of microstructural conditions via friction stir processing and post process annealing.The existence and extent of yield asymmetry ratio in the range of microstructural conditions was experimentally obtained through quasistatic tensile and compression tests.The yield asymmetry problem was profoundly present in specimens of coarse grained microstructures when compared to their fine grained and ultra fine grained counterparts.The impact of the microstructure and associated mechanisms of plasticity on the macroscopic strain hardening behavior was established by Kock–Mecking’s analysis.Crystal plasticity simulations using Viscoplastic Self Consistency approach revealed the consequential role of extension twinning mechanism for the existence of yield asymmetry and anomalies in strain hardening behavior.This was especially dominant with coarsening of grain size.Electron Microscopy and characterization were conducted thoroughly in partially deformed specimens to confirm the predictions of the above simulations.The role of crystallographic texture for inducing the polarity to Tension–Compression yield asymmetry was corroborated.A critical grain size in Magnesium–Silver–Rare earth alloy was hereby established which could nullify influences of extension twinning in yield asymmetry ratio. | Sourav Mishra F.Khan S.K.Panigrahi | 2022 | Journal of Magnesium and Alloys2022,10,9: | 2 |
| 12 | Ultra-highly diluted plant extracts of Hydrastis canadensis and Marsdenia condurango induce epigenetic modifications and alter gene expression profiles in HeLa cells in vitro显示文摘OBJECTIVE: Methylation-specifi c epigenetic process and gene expression profi les of He La cells treated with ultra-high dilutions(HDs) of two plant extracts, Hydrastis canadensis(HC-30) and Marsdenia condurango(Condu-30), diluted 1060 times, were analyzed against placebo 30C(Pl-30) for alterations in gene profi les linked to epigenetic modifi cations.METHODS: Separate groups of cells were subjected to treatment of Condu-30, HC-30, and Pl-30 prepared by serial dilutions and succussions. Global microarray data recorded on Affymetrix platform, using 25-mer probes were provided by i Life Discoveries, India. Slides were scanned with 3000 7G microarray scanner and raw data sets were extracted from Cel(raw intensity) fi les. Analyses of global microarray data profi le, differential gene expression, fold change and clusters were made using Gene Spring GX12.5 software and standard normalization procedure. Before microarray study, concentration of RNA(ng/μL), RIN value and r RNA ratio for all the samples were analysed by Agilant Bioanalyzer 2100. Reverse transcriptase polymerase chain reaction(RT-PCR) and quantitative RTPCR were done for analyzing SMAD-4 expression. Fluorescence-activated cell sorting study was further made to elucidate fate of cells at divisional stages. Methylation-specifi c restriction enzyme assay was conducted for ascertaining methylation status of DNA at specifi c sites.RESULTS: HDs of HC-30 and Condu-30 differentially altered methylation in specifi c regions of DNA and expression profi les of certain genes linked to carcinogenesis, as compared to Pl-30. Two separate cut sites were found in genomic DNA of untreated and placebo-treated He La cells when digested with McrB C, compared to a single cut observed in Condu-30-treated genomic DNA. SMAD-4 gene expression validated the expression pattern observed in microarray profi le. Methylation-specifi c restriction enzyme assay elucidated differential epigenetic modifi cations in drug-treated and control cells.CONCLUSION: HDs triggered epigenetic modifi cations and alterations in microarray gene expression profi les of many genes associated with carcinogenesis in HeLa cells in vitro. | Santu Kumar Saha Sourav Roy Anisur Rahman Khud a-Bukhsh | 2015 | Journal of Integrative Medicine2015,13,6: | 2 |
| 13 | Evaluation of chemopreventive potentials of ethanolic extract of Ruta graveolens against A375 skin melanoma cells in vitro and induced skin cancer in mice in vivo显示文摘OBJECTIVE: Chemopreventive approach with natural products, particularly plants and plant-derived ones, is receiving increasing attention for their effective role against cancer without any palpable side effects. In this study, efficacy of ethanolic extract of Ruta graveolens(RG) on skin melanoma cells(A375) in vitro and on 7,12-dimethylbenz(a)anthracene(DMBA)-induced skin cancer in vivo has been tested in Swiss albino mice.METHODS: Studies on cell viability, apoptosis and autophagy induction were conducted in vitro. To check apoptosis, assays like alteration in mitochondrial membrane potential, annexin V-fluorescein isothiocyanate/propidium iodide assay and immunoblot were performed. Fluorescence microscopic and immunoblot assays were performed to confirm autophagy induction. The effects of RG were determined by evaluating body weight, tumor incidence, tumor volume and tumor burden in mice. Enzymatic and non-enzymatic antioxidant status was assessed. The role of some relevant signaling proteins was also analyzed.RESULTS: RG caused death of A375 cells through induction of caspase 3-mediated apoptosis and Beclin-1-associated autophagy. Moreover, RG administration(75 mg/kg body weight) which showed no acute or chronic toxicity, showed significant reduction in the skin tumor burden of DMBA-painted mice. RG also demonstrated potent anti-lipid peroxidative and antioxidant functions during the course of skin cancer induction by DMBA.CONCLUSION: Chemopreventive potential of RG was demonstrated from overall results of this study, indicating its possible use in therapeutic formulation of an effective drug to treat skin cancer. | Samrat Ghosh Sourav Sikdar Avinaba Mukherjee Anisur Rahman Khuda-Bukhsh | 2015 | Journal of Integrative Medicine2015,13,1: | 2 |
| 14 | Observation of Resistive Switching Memory by Reducing Device Size in a New Cr/CrO_x/TiO_x/TiN Structure显示文摘The resistive switching memory characteristics of 100 randomly measured devices were observed by reducing device size in a Cr/Cr Ox/Ti Ox/Ti N structure for the first time.Transmission electron microscope image confirmed a viahole size of 0.4 lm.A 3-nm-thick amorphous Ti Oxwith 4-nm-thick polycrystalline Cr Oxlayer was observed.A small 0.4-lm device shows reversible resistive switching at a current compliance of 300 l A as compared to other larger size devices(1–8 lm)owing to reduction of leakage current through the Ti Oxlayer.Good device-to-device uniformity with a yield of[85%has been clarified by weibull distribution owing to higher slope/shape factor.The switching mechanism is based on oxygen vacancy migration from the Cr Oxlayer and filament formation/rupture in the Ti Oxlayer.Long read pulse endurance of[105cycles,good data retention of 6 h,and a program/erase speed of 1 ls pulse width have been obtained. | Debanjan Jana Subhranu Samanta Sourav Roy Yu Feng Lin Siddheswar Maikap | 2015 | Nano-Micro Letters2015,7,4: | 2 |
| 15 | Do the modified uncertainty principle and polymer quantization predict same physics显示文摘 | Barun Majumder Sourav Sen | 2012 | Phys Lett B2012,717,: | 1 |
| 16 | Bio2X:A rule-based Approach for Semi-automatic Transformation of Sem-structured Biological Data to XML显示文摘 | Song Yang Sourav S | 2005 | Data & Knowledge Engineering2005,52,: | 1 |
| 17 | Self-assembled betulinic acid protects doxorubicin induced apoptosis followed by reduction of ROS TNF-αcaspase-3 activity显示文摘 | Sandeep K D Sourav C Totan G | 2015 | Biomed Pharmacother2015,72,: | 1 |
| 18 | A Survey of Web Metrics 显示文摘 | Devanshu Dhyani Wee Keong Ng Sourav S Bhowmick | 2002 | ACM Comput Survey2002,34,4: | 1 |
| 19 | Study of a possible S = + 1 dynamically generated baryonic resonance显示文摘 | Sourav Sarkar E. Oset M. J. Vicente Vacas | 2005 | The European Physical Journal A2005,,2: | 1 |
| 20 | Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication显示文摘 | Renate K?nig Yingyao Zhou Daniel Elleder Tracy L. Diamond Ghislain M.C. Bonamy Jeffrey T. Irelan Chih-yuan Chiang Buu P. Tu Paul D. De Jesus Caroline E. Lilley Shannon Seidel Amanda M. Opaluch Jeremy S. Caldwell Matthew D. Weitzman Kelli L. Kuhen Sourav B | 2008 | Cell2008,,1: | 1 |