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| 1 | Association of p53/p21 expression with cigarette smoking and prognosis in esophageal squamous cell carcinoma patients显示文摘factors,such as cigarette smoking,in esophageal squamous cell carcinoma(ESCC)in northeastern Iran,a region with a high incidence of ESCC.METHODS:The expression of p53 and p21 proteins was investigated immunohistochemically in tumor tissue from 80 ESCC patients and in 60 available paraffinembedded blocks of adjacent normal specimens from the cases,along with normal esophageal tissue from 80 healthy subjects.RESULTS:Positive expression of p53 protein was detected in 56.2%(45/80)of ESCC cases,and in none of the normal esophageal tissue of the control group(P<0.001).Furthermore,73.8%(59/80)of ESCC cases and 43.8%(35/80)of controls had positive expression of p21 protein(P<0.001).Cigarette smoking was significantly associated with p53 over-expression in ESCC cases(P=0.010,OR=3.64;95%CI:1.32-10.02).p21 over-expression was associated with poorer clinical outcome among the ESCC patients(P=0.009).CONCLUSION:Over-expression of p53 in association with cigarette smoking may play a critical role in ESCC carcinogenesis among this high-risk population of northeastern Iran.Furthermore,p21 over-expression was found to be associated with poor prognosis,specifically in the operable ESCC patients. | Noushin Taghavi Firouzeh Biramijamal Masoud Sotoudeh Omeed Moaven Hooman Khademi Mohammad Reza Abbaszadegan Reza Malekzadeh | 2010 | World Journal of Gastroenterology2010，16，39： | 10 |
| 2 | A review on dural tail sign显示文摘'Dural tail sign' (DTS) which is a thickening of the dura adjacent to an intracranial pathology on contrast-enhanced T1 MR Images, was first thought to be pathognomonic of meningioma, however, many subsequent studies demonstrated this sign adjacent to various intra and extra-cranial pathologies and in spinal lesions. In this paper we outline the history, accompanying pathologies and the differentiation and probable pathophysiology of DTS. We also discuss whether we can predict tumoral involvement of the dural tail before surgery and whether the dural tail adjacent to a tumor should be resected. | Houman Sotoudeh Hadi Rokni Yazdi | 2010 | World Journal of Radiology2010，2，5： | 4 |
| 3 | Evaluation of fitness of design in urban historical context: From the perspectives of residents显示文摘 | Hesamaddin Sotoudeh Wan Mohd Zakri Wan Abdullah | 2013 | Frontiers of Architectural Research2013，2，1： | 4 |
| 4 | A new framework for evaluation of rock fragmentation in open pit mines显示文摘The main purpose of blasting in open pit mines is to produce the feed for crushing stage with the optimum dimensions from in situ rocks. The size distribution of muck pile indicates the efficiency of blasting pattern to reach the required optimum sizes. Nevertheless, there is no mature model to predict fragmentation distribution to date that can be used in various open pit mines. Therefore, a new framework to evaluate and predict fragmentation distribution is presented based on the image analysis approach. For this purpose, the data collected from Jajarm bauxite mine in Iran were used as the sources in this study. The image analysis process was performed by Split-Desktop software to find out fragmentation distribution, uniformity index and average size of the fragmented rocks. Then, two different approaches including the multivariate regression method and the decision-making trial and evaluation laboratory(DEMATEL) technique were incorporated to develop new models of the uniformity index and the average size to improve the Rosin-Rammler function. The performances of the proposed models were evaluated in four blasting operation sites. The results obtained indicate that the regression model possesses a better performance in prediction of the uniformity index and the average size and subsequently the fragmentation distribution in comparison with DEMATEL and conventional Rosin-Rammler models. | Mohammad Babaeian Mohammad Ataei Farhang Sereshki Farzad Sotoudeh Sadjad Mohammadi | 2019 | Journal of Rock Mechanics and Geotechnical Engineering2019，11，2： | 2 |
| 5 | Ecologic study of serum selenium and upper gastrointestinal cancers in Iran显示文摘AIM: Both observational and experimental studies have shown that higher selenium status reduces the risk of upper gastrointestinal cancers in selenium deficient populations.Recent cancer registry data have shown very different rates of esophageal cancer (EC) and gastric cancer (GC) in four Provinces of Iran, namely Ardabil, Mazandaran, Golestan,and Kerman. The aim of this study was to have a preliminary assessment of the hypothesis that high rates of EC in Golestan and high rates of GC in Ardabil may be partly attributable to selenium deficiency.METHODS: We measured serum selenium in 300 healthy adults from ArdabU (n = 100), Mazandaran (n = 50), Golestan (n = 100), and Kerman (n = 50), using inductively coupled plasma, with dynamic reaction cell, mass spectrometry (ICP-DRC-MS) at the US Centers for Disease Control (Atlanta,Georgia).RESULTS: The median serum selenium concentrations were very different in the four Provinces. The medians (IQR) for selenium in Ardabil, Mazandarn, Golestan, and Kerman were 82 (75-94), 123 (111-132), 155 (141-173), and 119 (110-128) μg/L, respectively (P<0.001). The results of linear regression showed that the Province variable, by itself,explained 76% of the variance in log selenium (r^2 = 0.76).The proportion of the populations with a serum selenium more than 90μg/L (the concentration at which serum selenoproteins are saturated) was 100% in Golestan,Kerman, and Mazandaran but only 29% in ArdabU.CONCLUSION: Our findings suggest nat selenium defidency is not a major contributor to the high incidence of EC seen in northeastern Iran, but it may play a role in the high incidence of GC in Ardabil Province. | Mehdi Nouarie Akram Pourshams Farin Kamangar Masood Sotoudeh Mohammad Hossein Derakhshan Mobammad Reza Akbari Hafez Fakheri Mohammad Javad Zahedi Kathleen Caldwell Christian C.Abnet Philip R.Taylor Reza Malekzadeh Sanford M.Dawsey | 2004 | World Journal of Gastroenterology2004，10，17： | 2 |
| 6 | High prevalence of coeliac disease in apparently healthy Iranian blood donors显示文摘 | Bijan Shahbazkhani Reza Malekzadeh Masoud Sotoudeh Ketaion Fayaz Moghadam Mohammad Farhadi Reza Ansari Amin Elahyfar Kamran Rostami | 2003 | European Journal of Gastroenterology & Hepatology2003，，5： | 1 |
| 7 | A randomized clinical trial of prophylactic effects of vitamin D on differents indices of osteopehia of prematurity显示文摘 | Alizade P Naderi F Sotoudeh K | 2006 | Iranian J Publ Health2006，35，3： | 1 |
| 8 | Assessment and improvement of integrated HSE and macro-ergonomics factors by fuzzy cognitive maps:the case of a large gas refinery显示文摘 | Asadzadeh S M Azadeh A Negahban A Sotoudeh A | | 0，，4： | 1 |
| 9 | p16INK4a hypermethylation and p53, p16 and MDM2 protein expres- sion in Esophageal Squamous Cell Carcinoma 显示文摘 | Taghavi N Biramijamal F Sotoudeh M | 2010 | BMC Cancer2010，10，： | 1 |
| 10 | Lisinopril ameliorates paraquat-induced lung fibrosis 显示文摘 | Mohammadi-Karakani A Ghazi-Khansari M Sotoudeh M | 2006 | Clin Chim Acta2006，367，12： | 1 |
| 11 | Liver Histology Changes in Nonalcoholic Steatohepatitis after One Year of Treatment with Probucol显示文摘 | Shahin Merat Mohsen Aduli Rozana Kazemi Masoud Sotoudeh Nahid Sedighi Masoud Sohrabi Reza Malekzadeh | 2008 | Digestive Diseases and Sciences2008，，8： | 1 |
| 12 | Lisinopril ameliorates paraquat-induced lung fibrosis显示文摘 | Mohammadi-Karakani A Ghazi-Khansari M Sotoudeh M | 2006 | Clin ChimActa2006，367，9： | 1 |
| 13 | pl6INK4a hypermethylation and p53,p16 and MDM2 protein ex-pression in esophageal squamous cell carcinoma 显示文摘 | TAGHAVI N BIRAMIJAMAL F SOTOUDEH M | 2010 | BMC Can-cer2010，10，： | 1 |
| 14 | Potential of Electrospun CollagenfPVA Hybrid Nanofiber Scaffold without Cell Seeded in Cartilage Tissue Engineering 显示文摘 | Amir Sotoudeh Gholam Reza Abedi Masoud Soleimani | 2012 | Bio- medical Engineering2012，10，23： | 1 |
| 15 | Antifibrotic effect of captopril and enalaprilon paraquat-induced lung fibrosisin rats显示文摘 | Ghazi-Khansari M Mohammadi-Karakani A Sotoudeh M | 2007 | J Appl Toxicol2007，27，4： | 1 |
| 16 | Aceuracy and cut-off values of pepsinogens Ⅰ ,Ⅱ and gastrin 17 for diagnosis of gastric fundic atrophy : influence of gastritis显示文摘 | Nasrollahzadeh D Agheheli K Sotoudeh M | 2011 | PLoS One2011，6，26： | 1 |
| 17 | The role of insulin like growth factor (IGF)-1 and IGF-binding protein-S in diagnosis of Growth Hormone Deficiency in short stature children显示文摘 | Haghshenas Z Sotoudeh K Karamifar H Karamizadeh Z Amirhakimi G | 2009 | IndianJ Pediatr2009，76，7： | 1 |
| 18 | Liver Histology Changes in Nonalcoholic Steatohepatitis after One Year of Treatment with Probucol显示文摘 | Shahin Merat Mohsen Aduli Rozana Kazemi Masoud Sotoudeh Nahid Sedighi Masoud Sohrabi Reza Malekzadeh | 2008 | Digestive Diseases and Sciences2008，，8： | 1 |
| 19 | Lisinopril ameliorates paraquat-induced lung fibrosis显示文摘 | Mohammadi-Karakani A Ghazi-Khansari M Sotoudeh M | 2006 | Clin Chim Aeta2006，367，： | 1 |
| 20 | Prevalence of 'dural tail sign' in patients with different intracranial pathologies 显示文摘 | Rokni-Yazdi H Sotoudeh H | 2006 | Eur J Radiol2006，60，1： | 1 |
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