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| 1 | Application of artificial neural networks and multivariate statistics to estimate UCS using textural characteristics显示文摘Before any rock engineering project,mechanical parameters of rocks such as uniaxial compressive strength and young modulus of intact rock get measured using laboratory or in-situ tests,but in some situations preparing the required specimens is impossible.By this time,several models have been established to evaluate UCS and E from rock substantial properties.Artificial neural networks are powerful tools which are employed to establish predictive models and results have shown the priority of this technique compared to classic statistical techniques.In this paper,ANN and multivariate statistical models considering rock textural characteristics have been established to estimate UCS of rock and to validate the responses of the established models,they were compared with laboratory results.For this purpose a data set for 44 samples of sandstone was prepared and for each sample some textural characteristics such as void,mineral content and grain size as well as UCS were determined.To select the best predictors as inputs of the UCS models,this data set was subjected to statistical analyses comprising basic descriptive statistics,bivariate correlation,curve fitting and principal component analyses.Results of such analyses have shown that void,ferroan calcitic cement,argillaceous cement and mica percentage have the most effect on USC.Two predictive models for UCS were developed using these variables by ANN and linear multivariate regression.Results have shown that by using simple textural characteristics such as mineral content,cement type and void,strength of studied sandstone can be estimated with acceptable accuracy.ANN and multivariate statistical UCS models,revealed responses with 0.87 and 0.76 regressions,respectively which proves higher potential of ANN model for predicting UCS compared to classic statistical models. | Amin Manouchehrian Mostafa Sharifzadeh Rasoul Hamidzadeh Moghadam | 2012 | International Journal of Mining Science and Technology2012，22，2： | 13 |
| 2 | Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response显示文摘AIM: To investigate the co-incidence of apoptosis, autophagy, and unfolded protein response(UPR) in hepatitis B(HBV) and C(HCV) infected hepatocytes.METHODS: We performed immunofluorescence confocal microscopy on 10 liver biopsies from HBV and HCV patients and tissue microarrays of HBV positive liver samples. We used specific antibodies for LC3β, cleaved caspase-3, BIP(GRP78), and XBP1 to detect autophagy, apoptosis and UPR, respectively. AntiHCV NS3 and anti-HBs antibodies were also used to confirm infection. We performed triple blind counting of events to determine the co-incidence of autophagy(LC3β punctuate), apoptosis(cleaved caspase-3), and unfolded protein response(GRP78) with HBV and HCV infection in hepatocytes. All statistical analyses were performed using SPSS software for Windows(Version 16 SPSS Inc, Chicago, IL, United States). P-values < 0.05 were considered statistically significant. Statistical analyses were performed with Mann-Whitney test to compare incidence rates for autophagy, apoptosis, and UPR in HBV- and HCV-infected cells and adjacent noninfected cells.RESULTS: Our results showed that infection of hepatocytes with either HBV and HCV induces significant increase(P < 0.001) in apoptosis(cleavage of caspase-3), autophagy(LC3β punctate), and UPR(increase in GRP78 expression) in the HCV- and HBVinfected cells, as compared to non-infected cells of the same biopsy sections. Our tissue microarray immunohistochemical expression analysis of LC3β in HBV^(Neg) and HBV^(Pos) revealed that majority of HBVinfected hepatocytes display strong positive stainingfor LC3β. Interestingly, although XBP splicing in HBVinfected cells was significantly higher(P < 0.05), our analyses show a slight increase of XBP splicing was in HCV-infected cells(P > 0.05). Furthermore, our evaluation of patients with HBV and HCV infection based on stage and grade of the liver diseases revealed no correlation between these pathological findings and induction of apoptosis, autophagy, and UPR.CONCLUSION: The results of this study indicate that HCV and HBV infection activates apoptosis, autophagy and UPR, but slightly differently by each virus. Further studies are warranted to elucidate the interconnections between these pathways in relation to pathology of HCV and HBV in the liver tissue. | Behzad Yeganeh Adel Rezaei Moghadam Javad Alizadeh Emilia Wiechec Seyed Moayed Alavian Mohammad Hashemi Bita Geramizadeh Afshin Samali Kamran Bagheri Lankarani Martin Post Payam Peymani Kevin M Coombs Saeid Ghavami | 2015 | World Journal of Gastroenterology2015，21，47： | 13 |
| 3 | 丝胶茧蚕品种选育初报显示文摘利用家蚕资源库中的突变基因,初步育成了丝胶茧蚕品种。导入了与活性物质黄酮类产生有关的基因,使丝胶中含有特殊的功能性活性物质。为丝胶的保健食用和高档化妆品利用提供原料。 | 李军 费建明 李玉峰 Hosseiny Moghadam S.H 金卫明 徐孟奎 陈玉银 | 2006 | 蚕桑通报2006，37，3： | 12 |
| 4 | Selection of regression models for predicting strength and deformability properties of rocks using GA显示文摘Recently,many regression models have been presented for prediction of mechanical parameters of rocks regarding to rock index properties.Although statistical analysis is a common method for developing regression models,but still selection of suitable transformation of the independent variables in a regression model is diffcult.In this paper,a genetic algorithm(GA)has been employed as a heuristic search method for selection of best transformation of the independent variables(some index properties of rocks)in regression models for prediction of uniaxial compressive strength(UCS)and modulus of elasticity(E).Firstly,multiple linear regression(MLR)analysis was performed on a data set to establish predictive models.Then,two GA models were developed in which root mean squared error(RMSE)was defned as ftness function.Results have shown that GA models are more precise than MLR models and are able to explain the relation between the intrinsic strength/elasticity properties and index properties of rocks by simple formulation and accepted accuracy. | Manouchehrian Amin Sharifzadeh Mostafa Hamidzadeh Moghadam Rasoul Nouri Tohid | 2013 | International Journal of Mining Science and Technology2013，23，4： | 9 |
| 5 | 蚕品种选育多用途化发展趋势显示文摘为了满足蚕桑生产发展多元化和提升改造传统蚕桑业发展需要开展的特殊用途蚕品种选育进展迅速,本文就以蚕丝生产为目的如雄蚕品种、细纤度蚕品种、粗纤度蚕品种、人工饲料育品种及广食性蚕品种、天然彩色茧蚕品种等的选育,以及非蚕丝生产为目的如吐平面丝蚕品种、吐丝胶茧蚕品种、生物反应器专用蚕品种、药食专用蚕品种等育种研究进展进行概述。 | 杜鑫 费建明 李军 S.H.Hosseini Moghadam 陈玉银 | 2007 | 蚕桑通报2007，38，1： | 8 |
| 6 | Antibacterial activity of eight Iranian plant extracts against methicillin and cefixime restistant Staphylococcous aureus strains显示文摘Objective:To assess the antibacterial activity of eight Iranian plant extracts against Staphylococcus aureus(S.aureus) strains which were isolated from infected patients.Methods: The studied strains were isolated from urine,stool,blood and wound of infected patients and identified by biochemical tests.In further,the antibacterial activity of 8 ethanolic local plant extracts including Querqus brantii(Q.brantii),Ziziphus spina-christi(Z.spina-christi),Peganum harmala(P.harmala),Oliveira decumbens(O.decumbens),Galium tricornutum(G.tricornutum), Vitex pseudo negundo(Vi.pseudo negundo),Salvia officinalis(S.officinalis),Vaccaria pyramidata (V.pyramidata) were then evaluated using agar disc diffusion method.Results:A total of 9 isolates were isolated and identified as S.aureus.Antibacterial profile of the strains showed that the strains were resistant to methicillin and cefixime.The highest antibacterial activity against the studied strains were belong to Q.brantii,P.harmala,Z.spina-christi and O.decumbens vent extracts with 11-40 mm,15-28 mm,8-26 mm and 10-20 mm of diameters,respectively. Intermediate antibacterial activity was exhibited by G.tricornutum and Vi.pseudo negundo against some of the studied strains with 7-20 mm and 7-13 mm of diameters,respectively. Noteworthy,out of 9 studied strains;6 and 2 of them were resistant to the G.tricornutum and Vi. pseudo negundo extracts,respectively.The S.officinalis and Va.pyramidata,however,showed no antibacterial activity against the studied strains.Conclusions:The Q.brantii,P.harmala,Z. spina-christi and O.decumbens extracts were shown to possess strong antibacterial activity against methicillin and cefixime resistant S.aureus strains and can be considered as the promising natural antibiotics for treating the studied strains. | Morteza Shojaei Moghadam Susan Maleki Esmaeil Darabpour Hossein Motamedi Seyyed Mansour Seyyed Nejad | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，4： | 7 |
| 7 | Experimental evaluation of mechanically stabilized earth walls with recycled crumb rubbers显示文摘Traditional techniques for treatment of waste rubber, such as burning, generate some highly nondegradable synthetic materials that cause unrepairable environmental damages by releasing heavy metals, such as arsenic, chromium, lead, manganese and nickel. For this, scrap tires are used as lightweight alternative materials in many engineering applications, such as retaining wall backfilling. In the present study, 90 laboratory models were prepared to evaluate the stability of mechanically stabilized earth(MSE) walls with plate anchors. Then, the bearing capacity and horizontal displacements of the retaining walls were monitored by exerting a static loading to investigate the effects of adding different contents(5 wt%, 10 wt%, 15 wt% and 20 wt%) of recycled crumb rubber(RCR) to the fill of a mechanically stabilized retaining wall with plate anchors. To visualize the critical slip surface of the wall, the particle image velocimetry(PIV) technique was employed. Results showed that the circular anchor plates almost continually provided a higher bearing capacity and wall stability than the square plates. Moreover, the backfill with 15 wt% RCR provided the maximum bearing capacity of the wall. Increasing the weight percentage of RCR to 20 wt% resulted in a significant reduction in horizontal displacement of the wall,which occurred due to the decrease in lateral earth pressure against the whole walls. An increase in RCR content resulted in the decrease in the formation of failure wedge and the expansion of the wall slip surface, and the failure wedge did not form in the sand mixtures with 15 wt% and 20 wt% RCRs. | Matin Jalali Moghadam Amirali Zad Nima Mehrannia Nader Dastaran | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，5： | 6 |
| 8 | Fluid Flow and Heat Transfer Modeling of AC Arc in Ferrosilicon Submerged Arc Furnace显示文摘A two-dimensional mathematical model was developed to describe the heat transfer and fluid flow in an AC arc zone of a ferrosilicon submerged arc furnace.In this model,the time-dependent conservation equations of mass,momentum,and energy in the specified domain of plasma zone were numerically solved by coupling with the Maxwell and Laplace equations for magnetic filed and electric potential,respectively.A control volume-based finite difference method was used to solve the governing equations in cylindrical coordinates.The reliability of the developed model was checked by experimental data from the previous available literature.The results of present model were in good agreement with the given data comparing with other models,because of solving the Maxwell and Laplace equations simultaneously in order to calculate current density.In addition,parametric studies were carried out to evaluate the effects of electrical current and arc length on flow field and temperature distribution within the arc.According to the computed results,a lower power input led to a higher arc efficiency. | M Mohebi Moghadam S H Seyedein M Reza Aboutalebi | 2010 | Journal of Iron and Steel Research(International)2010，17，9： | 5 |
| 9 | Tunnel flexibility effect on the ground surface acceleration response显示文摘Flexibility of underground structures relative to the surrounding medium, referred to as the flexibility ratio, is an important factor that influences their dynamic interaction. This study investigates the flexibility effect of a box-shaped subway tunnel, resting directly on bedrock, on the ground surface acceleration response using a numerical model verified against dynamic centrifuge test results. A comparison of the ground surface acceleration response for tunnel models with different flexibility ratios revealed that the tunnels with different flexibility ratios influence the acceleration response at the ground surface in different ways. Tunnels with lower flexibility ratios have higher acceleration responses at short periods, whereas tunnels with higher flexibility ratios have higher acceleration responses at longer periods. The effect of the flexibility ratio on ground surface acceleration is more prominent in the high range of frequencies. Furthermore, as the flexibility ratio of the tunnel system increases, the acceleration response moves away from the free field response and shifts towards the longer periods. Therefore, the flexibility ratio of the underground tunnels influences the peak ground acceleration(PGA) at the ground surface, and may need to be considered in the seismic zonation of urban areas. | Mohammad Hassan Baziar asoud Rabeti Moghadam Yun Wook Choo Dong-Soo Kim | 2016 | Earthquake Engineering and Engineering Vibration2016，15，3： | 4 |
| 10 | Electro-spray of high viscous liquids for producing mono-sized spherical alginate beads显示文摘Alginate beads, often used for controlled release of enzymes and drugs, are usually produced by spraying sodium alginate liquid into a gelling agent using mechanical vibration nozzle or air jet. In this work an alternative method of electro-spray was employed to form droplets with desired size from a highly viscous sodium alginate solution using constant DC voltage. The droplets were then cured in a calcium chloride solution. The main objective was to produce mono-sized beads from such a highly viscous and non-Newtonian liquid (1000-5000 mPa s). The effects of nozzle diameter, flow rate and concentration of liquid on the size of the beads were investigated. Among the parameters studied, voltage had a pronounced effect on the size of beads as compared to flow rate, nozzle diameter and concentration of alginate liquid. The size of beads was reduced to a minimum value with increasing the voltage in the range of 0-10 kV. At the early stages of voltage increase (i.e. up to about 4 kV), the rate of size reduction was relatively low, while the dripping mode dominated. However, in the middle part of the range of applied voltage, where the rate of size reduction was high (i.e. about 4-7 kV), an unstable transition occurred between dripping and jetting. At the end part of the range (i.e. 7-10 kV) jet mode of spray was observed. Increasing the height of fall of the droplets was found to improve the sphericity of the beads, because of the increased time of flight for the droplets. This was especially identifiable at higher concentrations of the alginate liquid (i.e. 3 w/v%). | Hamid Moghadam Mohsen Samimi Abdolreza Samimi Mohamad Khorram | 2008 | Particuology2008，6，4： | 3 |
| 11 | Highly efficient and green synthesis of 14-aryl(alkyl)-14H-dibenzo[a,j]xanthene and 1,8-dioxooctahydroxanthene derivatives catalyzed by reusable zirconyl triflate[ZrO(OTf)_2]under solvent-free conditions显示文摘An efficient,convenient and green method has been introduced for the preparation of 14-aryl(alkyl)-14H-dibenzo[a,j]xanthene and 1,8-dioxooctahydroxanthene derivatives by the reaction of aldehydes with 2-naphthol and 5,5-dimethyl-1,3-cyclohexanedione, respectively,in the presence of ZrO(OTf)2 as a reusable catalyst under solvent-free conditions.In addition,very short reaction times, excellent yields,straightforward procedure,and relatively non-toxicity of the catalyst are other noteworthy advantages of the present method. | Iraj Mohammadpoor-Baltork Majid Moghadam Valiollah Mirkhani Shahram Tangestaninejad Hamid Reza Tavakoli | 2011 | Chinese Chemical Letters2011，22，1： | 3 |
| 12 | Ebola viral disease: a review literature显示文摘Ebola virus is transmitted to people as a result of direct contact with body fluids containing virus of an infected patient. The incubation period usually lasts 5 to 7 d and approximately95% of the patients appear signs within 21 d after exposure. Typical features include fever,profound weakness, diarrhea, abdominal pain, cramping, nausea and vomiting for 3-5days and maybe persisting for up to a week. Laboratory complications including elevated aminotransferase levels, marked lymphocytopenia, and thrombocytopenia may have occurred.Hemorrhagic fever occurs in less than half of patients and it takes place most commonly in the gastrointestinal tract. The symptoms progress over the time and patients suffer from dehydration, stupor, confusion, hypotension, multi-organ failure, leading to fulminant shock and eventually death. The most general assays used for antibody detection are direct IgG and IgM ELISAs and IgM capture ELISA. An IgM or rising IgG titer(four-fold) contributes to strong presumptive diagnosis. Currently neither a licensed vaccine nor an approved treatment is available for human use. Passive transfer of serum collected from survivors of Junin virus or Lassa virus, equine IgG product from horses hypervaccinated with Ebola virus, a 'cocktail'of humanized-mouse antibodies(ZMapp), recombinant inhibitor of factor VIIa/tissue factor,activated protein C, RNA-polymerase inhibitors and small interfering RNA nano particles are among the therapies in development. Preclinical evaluation is also underway for various vaccine candidates. One is a chimpanzee adenovirus vector vaccine; other vaccines involve replication-defective adenovirus serotype 5 and recombinant vesicular stomatitis virus. | Saeed Reza Jamali Moghadam Negar Omidi Samaneh Bayrami Sepideh Jamali Moghadam SeyedAhmad SeyedAlinaghi | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，4： | 2 |
| 13 | 磁性纳米粒子负载木瓜蛋白酶的制备、表征及用于果汁澄清(英文)显示文摘The preparation,characterization,and application of silica-coated magnetic nanoparticles for papain immobilization is reported.Papain was covalently attached onto the(3-chloropropyl) trimethoxysilane-modified silica-coated magnetic nanoparticles. The enzyme-immobilized nanoparticles were characterized by Fourier transform infrared spectroscopy,X-ray powder diffraction,scanning electron microscopy,and vibrating sample magnetometry techniques.Response surface methodology combined with statistical analyses using Minitab were employed to evaluate optimum operating conditions to immobilize papain on the magnetic nanoparticles.The optimum conditions were: temperature = 27.3℃,pH of the enzyme solution = 7.1,concentration of papain = 3.3 mg/mL,and immobilization time = 10 h.Compared with the free papain,the immobilized papain displayed enhanced enzyme activity,better tolerance to variations in the medium pH and temperature,improved storage stability,and good reusability.Both the free and immobilized enzymes were effective for the clarification of pomegranate juice. | Leila Mosafa Majid Moghadam Mohammad Shahedi | 2013 | 催化学报2013，34，10： | 2 |
| 14 | Expeditious solvent-free synthesis of 1,3-thiazolanes via multicomponent reactions显示文摘A series of 1 3-thiazolane derivatives have been synthesized via multicomponent reactions of activated acetylenes,primary amines and isothiocyanates in the presence of a catalytic amount of Nmethylimidazole under solvent-free conditions. | Zinatossadat Hossaini Faramarz Rostami-Charati Mahboube Eslami Moghadam Fatemeh Moghaddasi-Kochaksaraee | 2014 | Chinese Chemical Letters2014，25，5： | 2 |
| 15 | Nanostructured food proteins as efficient systems for the encapsulation of bioactive compounds显示文摘Recently,nanoencapsulation was introduced as an efficient and promising approach for the protection,delivery,and site-specific liberation of the nutraceuticals and bioactive ingredients.Food proteins are attractive materials for developing nanocarriers to protect and deliver bioactives due to their unique functional and biological properties.Food proteins extracted from animals and plants have the ability to form different nanostructures including nanoparticles,hollow particles,nanogels,nanofibrillar aggregates,electrospun nanofibers,nanotubular structures,and nanocomplexes.These nanostructured food proteins have been widely used as nanocarriers for the biologically active compounds and drugs.The release of bioactive compounds from nanocarriers depends mainly on pH as well as swelling and the degradation behavior of nanostructure in the simulated physiological conditions.This review presents the applications of the nanostructured food proteins for the encapsulation of bioactive compounds.The major techniques for the fabrication of nanocarriers are described.The encapsulation,protection,and release of bioactive compounds in different nanostructured food proteins were also discussed. | Mehdi Mohammadian Mostafa I.Waly Maryam Moghadam Zahra Emam-Djomeh Maryam Salami Ali Akbar Moosavi-Movahedi | 2020 | Food Science and Human Wellness2020，9，3： | 2 |
| 16 | Human microbiome and prostate cancer development:current insights into the prevention and treatment显示文摘The huge communities of microorganisms that symbiotically colonize humans are recognized as significant players in health and disease.The human microbiome may influence prostate cancer development.To date,several studies have focused on the effect of prostate infections as well as the composition of the human microbiome in relation to prostate cancer risk.Current studies suggest that the microbiota of men with prostate cancer significantly differs from that of healthy men,demonstrating that certain bacteria could be associated with cancer development as well as altered responses to treatment.In healthy individuals,the microbiome plays a crucial role in the maintenance of homeostasis of body metabolism.Dysbiosis may contribute to the emergence of health problems,including malignancy through affecting systemic immune responses and creating systemic inflammation,and changing serum hormone levels.In this review,we discuss recent data about how the microbes colonizing different parts of the human body including urinary tract,gastrointestinal tract,oral cavity,and skin might affect the risk of developing prostate cancer.Furthermore,we discuss strategies to target the microbiome for risk assessment,prevention,and treatment of prostate cancer. | Solmaz Ohadian Moghadam Seyed Ali Momeni | 2021 | Frontiers of Medicine2021，15，1： | 2 |
| 17 | Polyacrylamide hydrogel application in sand control with compressive strength testing显示文摘Sand production is one of the major problems in sandstone reservoirs. Different mechanical and chemical methods have been proposed to control sand production. In this paper, we propose a chemical method based on using polyacrylamide/chromium triacetate hydrogel to investigate sand production in a synthetic sandpack system. To this end, a series of bulk experiments including the bottle test and rheological analysis along with compression tests were conducted. Experimental results indicated that the compressive strength of the sandpack was increased as much as 30 times by injecting 0.5 pore volume of hydrogel. Also, it was found that the increases in cross-linker and polymer concentrations exhibited a positive impact on the compressive strength of the sandpack, mostly by cross-linker concentration(48 psi). Hydrogel with a higher value of cross-linker could retain its viscoelastic properties against the strain which was a maximum of 122% for 0.5 weight ratio of cross-linker/polymer. The presence of salts, in particular divalent cations, has a detrimental effect on the hydrogel stability. The maximum strain value applied on hydrogel in the presence of CaCl_2 was only about 201% as compared to 1010% in the presence of distilled water. Finally, thermogravimetric analysis and its derivative showed that the hydrogel could retain its structure up to 300 °C. The results of this study revealed the potential application of the hydrogel to control sand production. | Mahsa Baghban Salehi Asefe Mousavi Moghadam Samira Zargari MarANDi | 2019 | Petroleum Science2019，16，1： | 2 |
| 18 | Fast vanishing point detection in unstructured environments 显示文摘 | Moghadam P Starzyk J Wijesoma W | 2012 | IEEE Transactions on Image Processing2012，21，1： | 1 |
| 19 | Cyclin D1 binding to the androgen receptor(AR) NH2-terminal domain inhibits activation function 2 association and reveals dual roles for AR corepression显示文摘 | Burd C J Petre C E Moghadam H | 2005 | Mol Endocrinol2005，19，3： | 1 |
| 20 | High prevalence of coeliac disease in apparently healthy Iranian blood donors显示文摘 | Bijan Shahbazkhani Reza Malekzadeh Masoud Sotoudeh Ketaion Fayaz Moghadam Mohammad Farhadi Reza Ansari Amin Elahyfar Kamran Rostami | 2003 | European Journal of Gastroenterology & Hepatology2003，，5： | 1 |
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