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| 1 | Oral microbiota:A new view of body health显示文摘Oral microbiota is an important part of the human microbiota.Oral microbes can be colonized into the intestine in various ways.Oral microbiota is associated with a variety of oral diseases.Recently,increasing evidence has shown that the oral microbiota is closely related to the physical state of humans,such as diabetes,obesity,and cancer.In the future,oral microbiota will become a new target for improving the physical state of humans. | Maoyang Lu Songyu Xuan Zhao Wang | 2019 | Food Science and Human Wellness2019，8，1： | 7 |
| 2 | Laser direct writing and characterizations of flexible piezoresistive sensors with microstructures显示文摘Functional materials with high viscosity and solid materials have received more and more attentions in flexible pressure sensors,which are inadequate in the most used molding method.Herein,laser direct writing(LDW)method is proposed to fabricate flexible piezoresistive sensors with microstructures on PDMS/MWCNTs composites with an 8%MWCNTs mass fraction.By controlling laser energy,microstructures with different geometries can be obtained,which significantly impacts the performances of the sensors.Subsequently,curved microcones with excellent performance are fabricated under parameters of f=40 kHz and v=150 mm·s^(-1).The sensor exhibits continuous multi-linear sensitivity,ultrahigh original sensitivity of 21.80%kPa^(-1),wide detection range of over 20 kPa,response/recovery time of~100 ms and good cycle stability for more than 1000 times.Besides,obvious resistance variation can be observed when tiny pressure(a peanut of 30 Pa)is applied.Finally,the flexible piezoresistive sensor can be applied for LED brightness controlling,pulse detection and voice recognition. | Chenying Zhang Wei Zhou Da Geng Cheng Bai Weida Li Songyue Chen Tao Luo Lifeng Qin Yu Xie | 2021 | Opto-Electronic Advances2021，4，4： | 7 |
| 3 | Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese显示文摘Apoptosis plays a key role in inhibiting tumor growth, progression and resistance to anti-tumor therapy. We hypothesized that genetic variants in apoptotic genes may affect the prognosis of lung cancer. To test this hypothesis, we selected 38 potentially functional single nucleotide polymorphisms (SNPs) from 12 genes (BAX, BCL2, BID, CASP3, CASP6, CASP7, CASP8, CASP9, CASP10, FAS, FASLG and MCL1) involved in apoptosis to assess their prognostic significance in lung cancer in a Chinese case cohort with 568 non-small cell lung cancer (NSCLC) patients. Thirty-five SNPs passing quality control underwent association analyses, 11 of which were shown to be significantly associated with NSCLC survival (P<0.05). After Cox stepwise regression analyses, 3 SNPs were independently associated with the outcome of NSCLC (BID rs8190315: P=0.003; CASP9 rs4645981: P=0.007 and FAS rs1800682: P=0.016). A favorable survival of NSCLC was significantly associated with the genotypes of BID rs8190315 AG/GG (adjusted HR=0.65, 95% CI: 0.49-0.88), CASP9 rs4645981 AA (HR=0.22, 95% CI: 0.07-0.69) and FAS rs1800682 GG (adjusted HR=0.67, 95% CI: 0.46-0.97). Time-dependent receptor operation curve (ROC) analysis revealed that the area under curve (AUC) at year 5 was significantly increased from 0.762 to 0.819 after adding the risk score of these 3 SNPs to the clinical risk score. The remaining 32 SNPs were not significantly associated with NSCLC prognosis after adjustment for these 3 SNPs. These findings indicate that BID rs8190315, CASP9 rs4645981 and FAS rs1800682 polymorphisms in the apoptotic pathway may be involved in the prognosis of NSCLC in the Chinese population. | Songyu Cao Cheng Wang Xinen Huang Juncheng Dai Lingmin Hu Yao Liu Jiaping Chen Hongxia Ma Guangfu Jin Zhibin Hu Lin Xu Hongbing Shen | 2013 | The Journal of Biomedical Research2013，27，3： | 6 |
| 4 | An experimental investigation into the icing and melting process of a water droplet impinging onto a superhydrophobic surface显示文摘The freezing and melting process of a small water droplet on a superhydrophobic cold surface was investigated using the Laser Induced Fluorescence(LIF)technique.The superhydrophobic surface was prepared using a sol-gel method on a red copper test plate.From the obtained fluorescence images,the phase transition characteristics during the freezing and melting process of a water droplet were clearly observed.It was found that,at the beginning of the droplet freezing process,liquid water turned into ice at a very fast rate.Such phase transition process decreased gradually with time and the volume of frozen ice approached a constant value at the end of the icing process.In addition,the freezing time was found to reduce with the decrease of the test plate temperature.Besides,when the test plate temperature is relatively high,the effect of droplet volume on the freezing time is very significant.Over all,we provide some tentative insights into the microphysical process related to the icing and melting process of water droplets. | JIN ZheYan JIN SongYue YANG ZhiGang | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，11： | 5 |
| 5 | Tomato DCL2b is required for the biosynthesis of 22-nt small RNAs, the resulting secondary siRNAs, and the host defense against ToMV显示文摘The tomato encode four functional DCL families,of which DCL2 is poorly studied.Here,we generated loss-of-function mutants for a tomato DCL2 gene,dcl2b,and we identified its major role in defending against tomato mosaic virus in relation to both natural and manual infections.Genome-wide small RNA expression profiling revealed that DCL2b was required for the processing 22-nt small RNAs,including a few species of miRNAs.Interestingly,these DCL2b-dependent 22-nt miRNAs functioned similarly to the DCL1-produced 22-nt miRNAs in Arabidopsis and could serve as triggers to generate a class of secondary siRNAs.In particular,the majority of secondary siRNAs were derived from plant defense genes when the plants were challenged with viruses.We also examined differentially expressed genes in dcl2b through RNA-seq and observed that numerous genes were associated with mitochondrial metabolism and hormone signaling under virus-free conditions.Notably,when the loss-of-function dcl2b mutant was challenged with tomato mosaic virus,a group of defense response genes was activated,whereas the genes related to lipid metabolism were suppressed.Together,our findings provided new insights into the roles of tomato DCL2b in small RNA biogenesis and in antiviral defense. | Tian Wang Zhiqi Deng Xi Zhang Hongzheng Wang Yu Wang Xiuying Liu Songyu Liu Feng Xu Tao Li Daqi Fu Benzhong Zhu Yunbo Luo Hongliang Zhu | 2018 | Horticulture Research2018，5，1： | 4 |
| 6 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang Yu Wenbing | 2002 | Cold Regions Science and Technology2002，，1： | 4 |
| 7 | Mechanical performances and microstructural characteristics of reactive MgO-carbonated silt subjected to freezing-thawing cycles显示文摘The characteristics of reactive magnesia(MgO)-carbonated silt in respect to long-term stability have not been well understood in severely cold climate despite the usage of reactive MgO in enhancing the engineering performances.Under the binder content of 15%and initial water content of 25%,MgO-admixed silt specimens were carbonized for 3 h and 6 h and then subjected to different numbers of freezingthawing(F-T)cycles.After different F-T cycles,the physico-mechanical properties of MgO-carbonated silt were analyzed in comparison with Portland cement(PC)-stabilized silt through physical and unconfined compression tests.Besides,a series of micro tests on MgO-carbonated specimens was performed including X-ray diffraction(XRD),scanning electron microscopy(SEM)and mercury intrusion porosimetry(MIP)tests.The results demonstrate that both mass change ratio and moisture content of carbonated/stabilized silt decrease,and these values of MgO-carbonated silt are significantly lower while the density is higher compared to PC-stabilized silt.The strengths and moduli of MgO-carbonated silt are still two times higher than those of PC-stabilized specimens and the strength change ratio of keeps above0.8 after F-T cycles.There is no visible transformation between nesquehonite and dypingite/hydromagnesite,although the XRD peaks of nesquehonite decrease and the bonding and filling effects weaken slightly.After 6 and 10 F-T cycles,the pore-size characteristics changed from a unimodal distribution to a three-peak and bimodal distribution,respectively.The total,macro and large pore volumes increase obviously while the medium and small pore volumes decrease except for intra-aggregate pore.The findings show better F-T durability of MgO-carbonated silt,which would be helpful for facilitating the application of MgO carbonation in the soil treatment. | Guanghua Cai Songyu Liu Guangyin Du Zhen Chen Xu Zheng Jiangshan Li | 2021 | Journal of Rock Mechanics and Geotechnical Engineering2021，13，4： | 3 |
| 8 | Proteomic survey towards the tissue-specific proteins of mouse mitochondria显示文摘Mitochondrion plays the key functions in mammalian cells. It is believed that mitochondrion exerts the common biologic functions in many tissues, but also performs some specific functions correspondent with tissues where it is localized. To identify the tissue-specific mitochondrial proteins, we carried out a systematic survey towards mitochondrial proteins in the tissues of C57BL/6J mouse, such as liver, kidney and heart. The mitochondrial proteins were separated by 2DE and identified by MALDI-TOF/TOF MS. Total of 87 unique proteins were identified as the tissue-specific ones, and some representatives were further verified through ICPL quantification and Western blot. Because these issue-specific proteins are coded from nuclear genes, real-time PCR was employed to examine the mRNA status of six typical genes found in the tissues.With combining of the expression data and the co-localization images obtained from confocal microscope, we came to the conclusion that the tissue-specifically mitochondrial proteins were widely distributed among the mouse tissues. Our investigation, therefore, indeed provides a solid base to further explore the biological significance of the mitochondrial proteins with tissue-orientation. | WANG Yuan SUN HaiDan RU YaWei YIN SongYue YIN Liang LIU SiQi | 2011 | Science China(Life Sciences)2011，54，1： | 3 |
| 9 | Experimentai Research on Saturated-Gain for Soft X-Ray Laser from Neon-Like Germanium Plasma显示文摘AmpliHcation of spontaneous emissions at 19.6,23.2 and 23.6 nm have been observed by a “ultiple-Target Series Coupling”design in Ge plasma,.The combined length for four targets is up to 56mm.The gain length product(GL)of small signal is up to 18 for both lines at 23.2 and 23.6 nmt and the effective GL is 16.4 and 15.7 for these two lines respectively.This two lines are obviously tending to saturation.The divergence of x-ray laser beam is about 4 mrad. | WANG Shiji GU Yuan ZHOU GuanUn NI Yuanlong YU Songyu FU Sizu MAO Chusheng TAO Zucong CHEN Wannian LIN Zunqi FAN Dianyuan ZHANG Guoping SHENG Jiatian YANG Minglun ZHANG Tanxin SHAO Yunfeng PENG Huimin HE Xiantu YU Min | 1991 | Chinese Physics Letters1991，8，12： | 3 |
| 10 | Adaptive Model Predictive Control for Yaw System of Variable-speed Wind Turbines显示文摘Due to varying characteristics of the wind condition, the performance of the wind turbines can be optimized by adapting the parameters of the control system. In this letter, an adaptive technique is proposed for the novel model predictive control(MPC) for the yaw system of the wind turbines. The control horizon is adapted to the one with the best predictive performance among multiple control horizons. The adaptive MPC is demonstrated by simulations using real wind data, and its performance is compared with the baseline MPC at fixed control horizon. Results show that the adaptive MPC provides better comprehensive performance than the baseline ones at different preview time of wind directions. Therefore, the proposed adaptive technique is potentially useful for the wind turbines in the future. | Dongran Song Qing Chang Songyue Zheng Sheng Yang Jian Yang Young Hoon Joo | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，1： | 2 |
| 11 | Comparison of CPT charts for soil classification using PCPT data: Example from clay deposits in Jiangsu Province, China显示文摘 | Guojun Cai Songyu Liu Anand J. Puppala | 2011 | Engineering Geology2011，，1： | 2 |
| 12 | Osteopontin splice variants expressed by breast tumors regulate monocyte activation via MCP-1 and TGF-β1显示文摘Osteopontin (OPN ) ,多功能的 glycoprotein,有在 vitro 在肿瘤有不同角色的三个抄本。OPN 抄本是否在 vivo 在肿瘤进程有不同函数,是不清楚的。有免疫力的导出房间的 OPN 能支持肿瘤形成,这被报导了。我们建议导出肿瘤的 OPN 可以便于的一个假设由影响有免疫力的房间区别和功能的肿瘤免疫者逃跑。在这研究,我们构造了 OPN 抄本和 transfected 的 lentiviral 表示向量他们进 MCF-7 房间线。有 OPN 抄本的 MCF-7 房间 transfected 被注入裸体老鼠的腋窝,并且肿瘤生长被监视。结果证明所有 OPN 抄本支持了本地肿瘤形成,而是那在抄本之中没有重要差别。我们也调查了 coculturing 单核白血球肿瘤房间与肿瘤上层清液在单核白血球区别上表示的 OPN 的效果。我们与 OPN 相比发现 OPN-c upregulated CD163 层次 --and OPN-b;然而,任何一个都没抄本影响 HLA 医生和 CD206 层次。所有 OPN 抄本显著地禁止了 TNF-α并且由单核白血球提高了 IL-10 生产。而且,我们发现了 OPN 抄本的 overexpression 显著地 upregulated TGF-β 1 并且由肿瘤房间的 MCP-1 生产。用抵销抗体和 recombinant cytokines,我们发现由肿瘤房间的 OPN overexpressed 调整 TNF-α 的生产;并且由单核白血球的 IL-10 部分经由 MCP-1 和 TGF-β 1 分别地。一起,我们的结果证明 OPN 抄本没在 vivo 在乳癌形成有不同角色。我们也证明 OPN 经由 TGF-β 调整单核白血球的其他的激活; 1 并且 MCP-1,它可以为肿瘤代表另外的机制免疫者逃跑。 | Jintang Sun Alei Feng Songyu Chen Yun Zhang Qi Xie Meixiang Yang Qianqian Shao Jia Liu Qifeng Yang Beihua Kong Xun Qu | 2013 | Cellular & Molecular Immunology2013，10，2： | 2 |
| 13 | 数字化地震记录分析软件PITSA简介及使用说明显示文摘“九五”期间我们将建立一批数字化地震台站,紧接着就是数字化记录的常规处理和数字化资料的开发利用问题。这两方面的工作都离不开数字化记录的常规处理软件。由国际地震学和地球内部物理学协会(IASPEI)和联合国科教文组织(UNESCO)以及美国地震学会(SSA)联合推荐的由F.ScherbaumandJ.Johnson完成的一套优秀的数字化分析处理软件PITSA(ProgrammableInteractiveToolboxforSeismologicalAnalysis)是一套比较适合我国广大地震工作者使用的软件。PITSA的特点是:①在普通微机(PC机)上安装使用,要求的微机和外部环境都很低,容易安装,占据的硬盘空间小(约2M)字节;②功能很强,如部分放大,震相拾取、求震级、定震中、分量旋转等常规分析工作它都能很好完成,进一步的分析处理工作如数值微分、积分、基线校正、谱分析、滤波、相关、Hilbert变换,旋转分量、偏振滤波、交义谱、相关谱、画质点运动图、各种模拟地震图的仿真等,它都能方便地实现;③它是菜单操作式软件,易学易用;④我们已有现成的软件,并已被一些地震工作者开发利用。鉴于以上优点,故我们特出版此专辑? | JIN Changtai,WANG Songyue and SHENG Mingtao Changchun Institute of Applied Chemistry,Academia Sinica,130022 Changchun | 1997 | 地震地磁观测与研究1997，18，4： | 2 |
| 14 | Research of soil-water characteristics and shear strength features of nanyang expansive soil显示文摘 | Miao Linchang Liu Songyu Lai Yuanming | 2002 | Engineering Geology2002，65，： | 1 |
| 15 | Approxinmate analutical solutiong for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang etc | 2002 | Cold Regions Science and Technology2002，34，： | 1 |
| 16 | Implementation of a New MPEG - 2 Transport Stream Processor for Digital Television Broadcasting 显示文摘 | Liang Longfei Yu Songyu Wang Xingdong | 2002 | IEEE Transations on Broadcasting2002，48，4： | 1 |
| 17 | Storage scheme of system information for digital television receiver显示文摘 | Sun Lei Zhang Wenjun Yu Songyu | 2003 | IEEE Transactions on Consumer Electronics2003，49，1： | 1 |
| 18 | Rate Control for Real-time Video Network Transmission on End-to-End Ratedistortion and Application-oriented QoS显示文摘 | Xiong Hongkai Sun Jun Yu Songyu | 2005 | IEEE Transactions on Broadcasting2005，51，1： | 1 |
| 19 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | Lai Yuanming Liu Songyu Wu Ziwang Yu Wenbing | 2002 | Cold Regions Science and Technology2002，，1： | 1 |
| 20 | Approximate analytical solution for temperature fields in cold regions circular tunnels显示文摘 | LAI Yuanming LIU Songyu WU Ziwang | 2002 | Cold Regions Science and Technology2002，34，： | 1 |
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