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| 1 | Preliminary study on the production of transgenic mice harboring hepatitis B virus X gene显示文摘INTRODUCTIONDespiteoverwhelmingepidemiologicalevidencelinkingpersistentHepatitisBVirus(HBV)infectionandthedevelopmentofhepato... | ZHU Huan Zhang 1, CHENG Guo Xiang 2, CHEN Jian Qu 2, KUANG Shu Yuan 3, CHENG Yong 2, ZHANG Xin Li 1, Ll Hou Da 2, XU Shao Fu 2, SHI Jing Quan 1, QIAN Geng Sun 3 and GU Jian Ren 3 | 1998 | World Journal of Gastroenterology1998，4，6： | 14 |
| 2 | Laser direct writing and characterizations of flexible piezoresistive sensors with microstructures显示文摘Functional materials with high viscosity and solid materials have received more and more attentions in flexible pressure sensors,which are inadequate in the most used molding method.Herein,laser direct writing(LDW)method is proposed to fabricate flexible piezoresistive sensors with microstructures on PDMS/MWCNTs composites with an 8%MWCNTs mass fraction.By controlling laser energy,microstructures with different geometries can be obtained,which significantly impacts the performances of the sensors.Subsequently,curved microcones with excellent performance are fabricated under parameters of f=40 kHz and v=150 mm·s^(-1).The sensor exhibits continuous multi-linear sensitivity,ultrahigh original sensitivity of 21.80%kPa^(-1),wide detection range of over 20 kPa,response/recovery time of~100 ms and good cycle stability for more than 1000 times.Besides,obvious resistance variation can be observed when tiny pressure(a peanut of 30 Pa)is applied.Finally,the flexible piezoresistive sensor can be applied for LED brightness controlling,pulse detection and voice recognition. | Chenying Zhang Wei Zhou Da Geng Cheng Bai Weida Li Songyue Chen Tao Luo Lifeng Qin Yu Xie | 2021 | Opto-Electronic Advances2021，4，4： | 7 |
| 3 | Development of Chinese hybrid radiation adult phantoms and their application to external dosimetry显示文摘This paper presents the construction of Chinese hybrid radiation adult phantoms,which are compatible with anatomical parameters for the Chinese reference population.The phantoms were designed using polygonal mesh surface,which makes the phantom more flexible and realistic than previous generations.Voxelization of hybrid phantoms was performed to adopt Monte Carlo methods.External dose coefficients were calculated by Geant4 and compared to the ICRP reference phantom.The results show that the organ dose is different from ICRP116 with the low energy photons,which can be ascribed to the anatomy and topology difference of each organ.The effective dose of CHRAP is 19%higher than ICRP 116 in the energy range from10 to 100 keV and is almost the same in the energy range from 100 keV to 10 MeV.These phantoms can be used as the basic phantom to adjust the posture or organ volume to estimate dosimetry in medical and space explorations. | GENG ChangRan TANG XiaoBin HOU XiaoXiao SHU DiYun CHEN Da | 2014 | Science China(Technological Sciences)2014，57，4： | 4 |
| 4 | Application of phase-field method in rechargeable batteries显示文摘Rechargeable batteries have a profound impact on our daily life so that it is urgent to capture the physical and chemical fundamentals affecting the operation and lifetime.The phase-field method is a powerful computational approach to describe and predict the evolution of mesoscale microstructures,which can help to understand the dynamic behavior of the material systems.In this review,we briefly introduce the theoretical framework of the phase-field model and its application in electrochemical systems,summarize the existing phase-field simulations in rechargeable batteries,and provide improvement,development,and problems to be considered of the future phase-field simulation in rechargeable batteries. | Qiao Wang Geng Zhang Yajie Li Zijian Hong Da Wang Siqi Shi | 2020 | npj Computational Materials2020，，1： | 3 |
| 5 | A new diterpenoid from Euphorbia helioscopia显示文摘A new jatrophane-type diterpenoid,7β,14β,15β-triacetoxy-3β-benzoyloxy-9-oxojatropha-5E,11E-diene,named euphornin N was isolated from Euphorbia helioscopia L.The structure and relative stereochemistry of the new compound was elucidated by spectroscopic methods. | Geng, Di Shi, Yao Min, Zhi Da Liang, Jing Yu | 2010 | Chinese Chemical Letters2010，21，1： | 2 |
| 6 | Perspectives of SLIT/ROBO signaling in placental angiogenesis显示文摘 | Liao WX Wing DA Geng JG | | 0，，： | 1 |
| 7 | Perspectives of SLIT/ROBO signaling in placental anglogenesis 显示文摘 | Liao WX Wing DA Geng JG | 2010 | Histol Histopatbol2010，25，： | 1 |
| 8 | Perspectives of SLIT/ ROBO signaling in placental angiogenesis 显示文摘 | Liao WX Wing DA Geng J | 2010 | Histol His- topatho12010，25，9： | 1 |
| 9 | Perspectives of Slit/ROBO signaling in placental angiogenesis 显示文摘 | Liao WX Wing DA Geng JG | 2010 | Histol Histopathol2010，25，： | 1 |
| 10 | Numerical simulation on fluidization characteristics of tobacco particles in fluidized bed dryers 显示文摘 | Geng Fan Xu Da Yong Yuan Zhu Lin | 2009 | Chemical Engineering Journal2009，150，23： | 1 |
| 11 | Perspectives of SLiT/ROBO signaling in placental angiogenesis显示文摘 | Liao WX Wing DA Geng JG | 2010 | Histol Histopathol2010，25，9： | 1 |
| 12 | Intercellular adhesion molecule-1 gene K469E polymorphism and ischemic stroke: a case-control study in a Chinese population显示文摘 | Xiao Xia Li Jian Ping Liu Jin Quan Cheng Sheng Hong Han Yi Jie Geng Sheng Wei Shi Tong Gao Da Na Huang Shao Fa Nie | 2009 | Molecular Biology Reports2009，，6： | 1 |
| 13 | Co‑packaged optics(CPO):status,challenges,and solutions显示文摘Due to the rise of 5G,IoT,AI,and high-performance computing applications,datacenter trafc has grown at a compound annual growth rate of nearly 30%.Furthermore,nearly three-fourths of the datacenter trafc resides within datacenters.The conventional pluggable optics increases at a much slower rate than that of datacenter trafc.The gap between application requirements and the capability of conventional pluggable optics keeps increasing,a trend that is unsustainable.Copackaged optics(CPO)is a disruptive approach to increasing the interconnecting bandwidth density and energy efciency by dramatically shortening the electrical link length through advanced packaging and co-optimization of electronics and photonics.CPO is widely regarded as a promising solution for future datacenter interconnections,and silicon platform is the most promising platform for large-scale integration.Leading international companies(e.g.,Intel,Broadcom and IBM)have heavily investigated in CPO technology,an inter-disciplinary research feld that involves photonic devices,integrated circuits design,packaging,photonic device modeling,electronic-photonic co-simulation,applications,and standardization.This review aims to provide the readers a comprehensive overview of the state-of-the-art progress of CPO in silicon platform,identify the key challenges,and point out the potential solutions,hoping to encourage collaboration between diferent research felds to accelerate the development of CPO technology. | Min Tan Jiang Xu Siyang Liu Junbo Feng Hua Zhang Chaonan Yao Shixi Chen Hangyu Guo Gengshi Han Zhanhao Wen Bao Chen Yu He Xuqiang Zheng Da Ming Yaowen Tu Qiang Fu Nan Qi Dan Li Li Geng Song Wen Fenghe Yang Huimin He Fengman Liu Haiyun Xue Yuhang Wang Ciyuan Qiu Guangcan Mi Yanbo Li Tianhai Chang Mingche Lai Luo Zhang Qinfen Hao Mengyuan Qin | 2023 | Frontiers of Optoelectronics2023，16，1： | 1 |
| 14 | Transplantation of mesenchy- mal ceils rejuvenated by the overexpression of telomerase and myocar- din promotes revascularization and tissue repair in a murine model of hindlimb ischemia显示文摘 | Madonna R Taylor DA Geng YJ | 2013 | Circ Res2013，113，7： | 1 |
| 15 | Perspectives of SLIT/ROBO signaling in placental angiogenesis显示文摘 | Liao WX Wing DA Geng JG | | 0，，： | 1 |
| 16 | Perspectives of SLIT/ROBO signaling in placental angiogenesis 显示文摘 | Liao WX Wing DA Geng JG | 2010 | Histol Histopathol2010，25，9： | 1 |
| 17 | Impact of shock loading with mid-stage pulping wastewater on a magnetic micro-aerobic activated sludge system显示文摘The effect of mid-stage pulping wastewater(as shock load)on micro-aerobic magnetic activated sludge system was studied.Micro-aerobic activated sludge systems with and without magnetic particles were shocked with mid-stage wastewater for 16 days.“Recovery”experiments were conducted by using simulated wastewater for 12 days.Upon the addition of mid-stage wastewater,CODCr removal pertaining to the use of magnetic particles reached 71.57%and remained above 80%in the“recovery”experiment.However,the efficiency of the reactor in the absence of magnetic particles was only 37.29%,and reached about 40%in the“recovery”experiment.After the micro-aerobic activated sludge was shocked,the flocculation performance and surface properties of the sludge were analyzed,and the results showed that all indicators of the reactors in the presence of magnetic particles were superior to those of reactors without magnetic particles.After 12 days of“recovery”,the indicators of the sludge pertaining to the reactors containing magnetic particles“recovered”completely. | Huixia Lan Hao Zhang Da Yang Shiwen Geng Wei Wang Shanhong Lan | 2018 | Journal of Bioresources and Bioproducts2018，3，2： | 0 |
| 18 | Synergetic roadmap of carbon neutrality and clean air for China显示文摘It is well recognized that carbon dioxide and air pollutants share similar emission sources so that synergetic policies on climate change mitigation and air pollution control can lead to remarkable co-benefits on greenhouse gas reduction,air quality improvement,and improved health.In the context of carbon peak,carbon neutrality,and clean air policies,this perspective tracks and analyzes the process of the synergetic governance of air pollution and climate change in China by developing and monitoring 18 indicators.The 18 indicators cover the following five aspects:air pollution and associated weather-climate conditions,progress in structural transition,sources,inks,and mitigation pathway of atmospheric composition,health impacts and benefits of coordinated control,and synergetic governance system and practices.By tracking the progress in each indicator,this perspective presents the major accomplishment of coordinated control,identifies the emerging challenges toward the synergetic governance,and provides policy recommendations for designing a synergetic roadmap of Carbon Neutrality and Clean Air for China. | Qiang Zhang Zhicong Yin Xi Lu Jicheng Gong Yu Lei Bofeng Cai Cilan Cai Qimin Chai Huopo Chen Hancheng Dai Zhanfeng Dong Guannan Geng Dabo Guan Jianlin Hu Cunrui Huang Jianing Kang Tiantian Li Wei Li Yongsheng Lin Jun Liu Xin Liu Zhu Liu Jinghui Ma Guofeng Shen Dan Tong Xuhui Wang Xuying Wang Zhili Wang Yang Xie Honglei Xu Tao Xue Bing Zhang Da Zhang Shaohui Zhang Shaojun Zhang Xian Zhang Bo Zheng Yixuan Zheng Tong Zhu Jinnan Wang Kebin He | 2023 | Environmental Science and Ecotechnology2023，，4： | 0 |
| 19 | Direct Synthesis of Bienzyme-like Carbide-derived Carbons via Mild Electrochemical Oxidation of Ti_(3)AlC_(2)MAX显示文摘Objective To develop effective alternatives to natural enzymes,it is crucial to develop nanozymes that are economical,resource efficient,and environmentally conscious.Carbon nanomaterials that have enzyme-like activities have been extensively developed as substitutes for traditional enzymes.Methods Carbide-derived carbons(CDCs)were directly synthesized via a one-step electrochemical method from a MAX precursor using an ammonium bifluoride electrolyte at ambient conditions.The CDCs were characterized by systematic techniques.Results CDCs showed bienzyme-like activities similar to that of peroxidase and superoxide dismutase.We systematically studied the dependence of CDC enzyme-like activity on different electrolytes and electrolysis times to confirm activity dependence on CDC content.Additionally,the synthesis mechanism and CDC applicability were elaborated and demonstrated,respectively.Conclusion The demonstrated synthesis strategy eliminates tedious intercalation and delamination centrifugation steps and avoids using high concentrations of HF,high temperatures,and halogen gases.This study paves the way for designing two-dimensional material-based nanocatalysts for nanoenzyme and other applications. | FANG Yan Feng DING Xiao Teng XU Geng Fang GONG Shi Da NIU Yu Sheng YAO Zi Yu JIN Zhao Yong WANG Yao XU Yuan Hong | 2022 | Biomedical and Environmental Sciences2022，35，3： | 0 |
| 20 | GTPase-activating protein TBC1D5 coordinates with retromer to constrain synaptic growth by inhibiting BMP signaling显示文摘Formation and plasticity of neural circuits rely on precise regulation of synaptic growth.At Drosophila neuromuscular junction(NMJ),Bone Morphogenetic Protein(BMP)signaling is critical for many aspects of synapse formation and function.The evolutionarily conserved retromer complex and its associated GTPase-activating protein TBC1D5 are critical regulators of membrane trafficking and cellular signaling.However,their functions in regulating the formation of NMJ are less understood.Here,we report that TBC1D5 is required for inhibition of synaptic growth,and loss of TBC1D5 leads to abnormal presynaptic terminal development,including excessive satellite boutons and branch formation.Ultrastructure analysis reveals that the size of synaptic vesicles and the density of subsynaptic reticulum are increased in TBC1D5mutant boutons.Disruption of interactions of TBC1D5 with Rab7 and retromer phenocopies the loss of TBC1D5.Unexpectedly,we find that TBC1D5 is functionally linked to Rab6,in addition to Rab7,to regulate synaptic growth.Mechanistically,we show that loss of TBC1D5 leads to upregulated BMP signaling by increasing the protein level of BMP type Ⅱ receptor Wishful Thinking(Wit)at NMJ.Overall,our data establish that TBC1D5 in coordination with retromer constrains synaptic growth by regulating Rab7 activity,which negatively regulates BMP signaling through inhibiting Wit level. | Xiu Zhou Guangming Gan Yichen Sun Mengzhu Ou Junhua Geng Jing Wang Xi Yang Shu Huang Da Jia Wei Xie Haihuai He | 2023 | Journal of Genetics and Genomics2023，50，3： | 0 |
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